G B Segel
Affiliation: University of Rochester
- Anticoagulant proteins in childhood venous and arterial thrombosis: a reviewG B Segel
Division of Pediatric Hematology Oncology, Box 777, University of Rochester Medical Center, Children s Hospital at Strong, 601 Elmwood Avenue, Rochester, New York 14642, USA
Blood Cells Mol Dis 26:540-60. 2000....
- Early gene activation in chronic leukemic B lymphocytes induced toward a plasma cell phenotypeGeorge B Segel
Department of Pediatrics, and Unity Health System, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA
Blood Cells Mol Dis 30:277-87. 2003..These findings suggest that the products of these three genes may be central to early steps in the TPA-induced evolution of CLL B cells to a plasmacytic phenotype...
- Controversies in the diagnosis and management of childhood acute immune thrombocytopenic purpuraGeorge B Segel
Department of Pediatrics, Golisano Children s Hospital, University of Rochester School of Medicine, Rochester, New York 14642, USA
Pediatr Blood Cancer 53:318-24. 2009..Therefore, careful observation may be the best management option for the patient with ITP, in the absence of severe bleeding. The data available relevant to these issues are discussed...
- The paradox of the neutrophil's role in tissue injuryGeorge B Segel
Department of Pediatrics, University of Rochester Medical Center, Rochester, New York, USA
J Leukoc Biol 89:359-72. 2011..In this review, we summarize the evidence for its role as a mediator of tissue injury in these seven conditions, making it or its products potential therapeutic targets...
- Cloning of rabbit Cct6 and the distribution of the Cct complex in mammalian tissuesG J Schwartz
Department of Pediatrics, University of Rochester School of Medicine, Rochester, NY 14642, USA
Exp Nephrol 8:152-60. 2000..These data characterize the rabbit Cct6 subunit and compare it to its homologues. The Western analyses support the concept that Cct complex is widely distributed among tissues and highly conserved among eukaryotes...
- Uncommon phenotypes of acute myelogenous leukemia: basophilic, mast cell, eosinophilic, and myeloid dendritic cell subtypes: a reviewMarshall A Lichtman
University of Rochester Medical Center, Rochester, NY 14642, USA
Blood Cells Mol Dis 35:370-83. 2005..We discuss the features of these uncommon phenotypes and review the criteria used for their diagnosis...
- The Na+/H+ exchanger in immature and mature granulocytic HL-60 cells. Property changes induced by intracellular acidification and cell maturationM R Costa-Casnellie
Department of Medicine, University of Rochester Medical Center, New York 14642
J Biol Chem 263:11851-5. 1988..At lower intracellular pH, 5.9, the inhibition was mixed in both types of cells. Thus, the properties of the exchanger in granulocytic cells are influenced by the cell maturation stage and the intracellular pH...
- Photoinhibition of 2-amino-2-carboxybicyclo[2,2,1]heptane transport by O-diazoacetyl-L-serine. An initial step in identifying the L-system amino acid transporterG B Segel
Department of Pediatrics, University of Rochester School of Medicine, New York 14642
J Biol Chem 264:16399-402. 1989..Thus, photolysis of azaserine provides an initial step toward the identification of the L-system transporter...
- Prohibitin expression is increased in phorbol ester-treated chronic leukemic B-lymphocytesT J Woodlock
Department of Medicine, University of Rochester School of Medicine and Dentistry, Rochester, New York 14642, USA
Blood Cells Mol Dis 27:27-34. 2001..These data suggest that increased prohibitin expression is associated with and may facilitate B-cell maturation...