PATRICK DAVID SCHLOSS

Summary

Affiliation: University of Michigan
Country: USA

Publications

  1. pmc Status of the Archaeal and Bacterial Census: an Update
    Patrick D Schloss
    Department of Microbiology and Immunology, University of Michigan, Ann Arbor, Michigan, USA
    MBio 7:. 2016
  2. pmc The gut microbiome modulates colon tumorigenesis
    Joseph P Zackular
    Department of Microbiology and Immunology, University of Michigan, Ann Arbor, Michigan, USA
    MBio 4:e00692-13. 2013
  3. pmc Stabilization of the murine gut microbiome following weaning
    Patrick D Schloss
    Department of Microbiology and Immunology, University of Michigan, Ann Arbor, MI, USA
    Gut Microbes 3:383-93. 2012
  4. pmc Reducing the effects of PCR amplification and sequencing artifacts on 16S rRNA-based studies
    Patrick D Schloss
    Department of Microbiology and Immunology, University of Michigan, Ann Arbor, Michigan, United States of America
    PLoS ONE 6:e27310. 2011
  5. pmc Assessing and improving methods used in operational taxonomic unit-based approaches for 16S rRNA gene sequence analysis
    Patrick D Schloss
    Department of Microbiology and Immunology University of Michigan, Ann Arbor, MI 48109, USA
    Appl Environ Microbiol 77:3219-26. 2011
  6. pmc The effects of alignment quality, distance calculation method, sequence filtering, and region on the analysis of 16S rRNA gene-based studies
    Patrick D Schloss
    Department of Microbiology and Immunology, The University of Michigan, Ann Arbor, Michigan, USA
    PLoS Comput Biol 6:e1000844. 2010
  7. pmc A high-throughput DNA sequence aligner for microbial ecology studies
    Patrick D Schloss
    Department of Microbiology, University of Massachusetts, Amherst, Massachusetts, United States of America
    PLoS ONE 4:e8230. 2009
  8. pmc Introducing mothur: open-source, platform-independent, community-supported software for describing and comparing microbial communities
    Patrick D Schloss
    Department of Microbiology and Immunology, University of Michigan, Ann Arbor, MI 48109, USA
    Appl Environ Microbiol 75:7537-41. 2009
  9. doi request reprint Evaluating different approaches that test whether microbial communities have the same structure
    Patrick D Schloss
    Department of Microbiology, University of Massachusetts Amherst, Amherst, MA 01003, USA
    ISME J 2:265-75. 2008
  10. pmc A statistical toolbox for metagenomics: assessing functional diversity in microbial communities
    Patrick D Schloss
    Department of Microbiology, University of Massachusetts Amherst, Amherst, MA 01003, USA
    BMC Bioinformatics 9:34. 2008

Collaborators

Detail Information

Publications10

  1. pmc Status of the Archaeal and Bacterial Census: an Update
    Patrick D Schloss
    Department of Microbiology and Immunology, University of Michigan, Ann Arbor, Michigan, USA
    MBio 7:. 2016
    ..The success of ongoing efforts to use short-read sequencing to characterize archaeal and bacterial communities requires that researchers strive to expand the depth and breadth of this census...
  2. pmc The gut microbiome modulates colon tumorigenesis
    Joseph P Zackular
    Department of Microbiology and Immunology, University of Michigan, Ann Arbor, Michigan, USA
    MBio 4:e00692-13. 2013
    ....
  3. pmc Stabilization of the murine gut microbiome following weaning
    Patrick D Schloss
    Department of Microbiology and Immunology, University of Michigan, Ann Arbor, MI, USA
    Gut Microbes 3:383-93. 2012
    ..These results suggest a high degree of stability in the microbiome once the community reached the second state...
  4. pmc Reducing the effects of PCR amplification and sequencing artifacts on 16S rRNA-based studies
    Patrick D Schloss
    Department of Microbiology and Immunology, University of Michigan, Ann Arbor, Michigan, United States of America
    PLoS ONE 6:e27310. 2011
    ....
  5. pmc Assessing and improving methods used in operational taxonomic unit-based approaches for 16S rRNA gene sequence analysis
    Patrick D Schloss
    Department of Microbiology and Immunology University of Michigan, Ann Arbor, MI 48109, USA
    Appl Environ Microbiol 77:3219-26. 2011
    ..The ability to quickly and accurately assign sequences to OTUs and then obtain taxonomic information for those OTUs will greatly improve OTU-based analyses and overcome many of the challenges encountered with phylotype-based methods...
  6. pmc The effects of alignment quality, distance calculation method, sequence filtering, and region on the analysis of 16S rRNA gene-based studies
    Patrick D Schloss
    Department of Microbiology and Immunology, The University of Michigan, Ann Arbor, Michigan, USA
    PLoS Comput Biol 6:e1000844. 2010
    ..Taken together, these results urge caution in the design and interpretation of analyses using pyrosequencing data...
  7. pmc A high-throughput DNA sequence aligner for microbial ecology studies
    Patrick D Schloss
    Department of Microbiology, University of Massachusetts, Amherst, Massachusetts, United States of America
    PLoS ONE 4:e8230. 2009
    ..Furthermore, because the implementation is not connected to a specific database it is easy to generalize the method to reference alignments for any DNA sequence...
  8. pmc Introducing mothur: open-source, platform-independent, community-supported software for describing and comparing microbial communities
    Patrick D Schloss
    Department of Microbiology and Immunology, University of Michigan, Ann Arbor, MI 48109, USA
    Appl Environ Microbiol 75:7537-41. 2009
    ..This analysis of more than 222,000 sequences was completed in less than 2 h with a laptop computer...
  9. doi request reprint Evaluating different approaches that test whether microbial communities have the same structure
    Patrick D Schloss
    Department of Microbiology, University of Massachusetts Amherst, Amherst, MA 01003, USA
    ISME J 2:265-75. 2008
    ..These findings demonstrate that when correctly employed, the current statistical toolbox has the ability to address specific ecological questions concerning the differences between microbial communities...
  10. pmc A statistical toolbox for metagenomics: assessing functional diversity in microbial communities
    Patrick D Schloss
    Department of Microbiology, University of Massachusetts Amherst, Amherst, MA 01003, USA
    BMC Bioinformatics 9:34. 2008
    ..In this study, we developed and applied a suite of tools to describe and compare the richness, membership, and structure of microbial communities using peptide fragment sequences extracted from metagenomic sequence data...