Robert E Schifferle
Affiliation: University at Buffalo
- Nutrition and periodontal diseaseRobert E Schifferle
Department of Periodontics and Endodontics, School of Dental Medicine, University at Buffalo, State University of New York, 318 Foster Hall, 3435 Main Street, Buffalo, NY 14214 3092, USA
Dent Clin North Am 49:595-610, vii. 2005..This article discusses general concepts of nutrition and provides an overview of the current understanding of the relationship between nutrition and periodontal disease...
- Dependence of bacterial protein adhesins on toll-like receptors for proinflammatory cytokine inductionGeorge Hajishengallis
Department of Oral Biology, State University of New York at Buffalo, Buffalo, New York 14214, USA
Clin Diagn Lab Immunol 9:403-11. 2002..Our data suggest that the CD14-TLR2/4 system is involved in cytokine production and tolerance induction upon interaction with certain proinflammatory bacterial protein adhesins...
- Counteracting interactions between lipopolysaccharide molecules with differential activation of toll-like receptorsGeorge Hajishengallis
Department of Oral Biology, State University of New York at Buffalo, 14214, USA
Infect Immun 70:6658-64. 2002..Interactions between TLR2 and TLR4 agonists may be important in the regulation of inflammatory reactions...
- Role of the phosphatidylinositol 3 kinase-Akt pathway in the regulation of IL-10 and IL-12 by Porphyromonas gingivalis lipopolysaccharideMichael Martin
Department of Microbiology, University of Alabama, Birmingham, AL 35294, USA
J Immunol 171:717-25. 2003..gingivalis LPS affects the induction of key immunoregulatory cytokines that control both qualitative and quantitative aspects of innate and adaptive immunity...
- Differential interactions of fimbriae and lipopolysaccharide from Porphyromonas gingivalis with the Toll-like receptor 2-centred pattern recognition apparatusGeorge Hajishengallis
Center for Oral Health and Systemic Disease and Department of Periodontics Endodontics, University of Louisville Health Sciences Center, Louisville, KY 40292, USA
Cell Microbiol 8:1557-70. 2006..In summary, TLR2 activation by P. gingivalis LPS or fimbriae involves differential dependence on accessory signalling or ligand-binding receptors, which may differentially influence innate immune responses...
- The effects of Porphyromonas gingivalis LPS and Actinobacillus actinomycetemcomitans LPS on human dendritic cells in vitro, and in a mouse model in vivoRangsini Mahanonda
Department of Periodontology, Faculty of Dentistry, Chulalongkorn University, Bangkok, Thailand
Asian Pac J Allergy Immunol 24:223-8. 2006..In conclusion, stimulation by P. gingivalis LPS and A. actinomycetemcomitans LPS appears to bias Mo-DCs towards Th2 production...
- Lipopolysaccharides from atherosclerosis-associated bacteria antagonize TLR4, induce formation of TLR2/1/CD36 complexes in lipid rafts and trigger TLR2-induced inflammatory responses in human vascular endothelial cellsMartha Triantafilou
Infection and Immunity Group, School of Life Sciences, University of Sussex, Falmer, Brighton, BN1 9QG, UK
Cell Microbiol 9:2030-9. 2007..This antagonistic activity of H. pylori or P. gingivalis LPS, as well as their TLR2 activation capability may be associated with their ability to contribute to atherosclerosis...
- Serum IgG to heat shock proteins and Porphyromonas gingivalis antigens in diabetic patients with periodontitisTom J Sims
Department of Oral Medicine, University of Washington, Seattle WA 98195, USA
J Clin Periodontol 29:551-62. 2002..We have therefore hypothesized that profiles of serum autoantibody levels and IgG titers, to P. gingivalis-specific antigens may be useful in assessing risk for refractory periodontitis in such patients...