Mark Y Sangster
Affiliation: University of Tennessee
- An early CD4+ T cell-dependent immunoglobulin A response to influenza infection in the absence of key cognate T-B interactionsMark Y Sangster
Department of Immunology, St Jude Children s Research Hospital, Memphis, TN 38105, USA
J Exp Med 198:1011-21. 2003..Our study demonstrates a CD4+ T cell-dependent, antiviral IgA response that is generated in the absence of B cell signaling via MHC II or CD40, and is restricted exclusively to virus-specific B cells...
- Quantitative analysis of herpes simplex virus type 1-specific memory B cells generated by different routes of infectionDaisy J Vanitha
Department of Microbiology, M409 Walters Life Sciences Bldg, 1414 W Cumberland Ave, University of Tennessee, Knoxville, TN 37996, USA
Virology 360:136-42. 2007..Our findings indicate that the widespread dispersion of MBCs to lymphoid tissues throughout the body is largely independent of the route of infection, but may be influenced by tissue-specific factors...
- Pathogenesis of Hong Kong H5N1 influenza virus NS gene reassortants in mice: the role of cytokines and B- and T-cell responsesAleksandr S Lipatov
Department of Infectious Diseases Division of Virology, St Jude Children s Research Hospital, 332 North Lauderdale Street, Memphis, TN 38105 2794, USA
J Gen Virol 86:1121-30. 2005..This cytokine imbalance is reminiscent of the clinical findings in two humans who died of H5N1/97 infection and may explain the unusual severity of the disease...
- A strategy for selective, CD4+ T cell-independent activation of virus-specific memory B cells for limiting dilution analysisXiaofeng Li
Department of Microbiology, M409 Walters Life Sciences Bldg, University of Tennessee, Knoxville, 37996, USA
J Immunol Methods 313:110-8. 2006..This strategy eliminates the influence of poorly defined T cell-associated factors on MBC frequency determinations...
- Broad dispersion and lung localization of virus-specific memory B cells induced by influenza pneumoniaHye Mee Joo
Department of Microbiology, University of Tennessee, Knoxville, TN 37996, USA
Proc Natl Acad Sci U S A 105:3485-90. 2008..Our findings provide insights into the pattern of B(Mem) dispersion, and emphasize the lung as a complex repository of immune memory after local infection...
- Induction of influenza virus-specific memory B cellsMARK SANGSTER; Fiscal Year: 2005..In addition, the systems established could be used in many other ways to address mechanistic questions related to the generation and maintenance of B cell memory. ..