Mark Y Sangster

Summary

Affiliation: University of Tennessee
Country: USA

Publications

  1. pmc An early CD4+ T cell-dependent immunoglobulin A response to influenza infection in the absence of key cognate T-B interactions
    Mark Y Sangster
    Department of Immunology, St Jude Children s Research Hospital, Memphis, TN 38105, USA
    J Exp Med 198:1011-21. 2003
  2. pmc Quantitative analysis of herpes simplex virus type 1-specific memory B cells generated by different routes of infection
    Daisy J Vanitha
    Department of Microbiology, M409 Walters Life Sciences Bldg, 1414 W Cumberland Ave, University of Tennessee, Knoxville, TN 37996, USA
    Virology 360:136-42. 2007
  3. ncbi request reprint Pathogenesis of Hong Kong H5N1 influenza virus NS gene reassortants in mice: the role of cytokines and B- and T-cell responses
    Aleksandr S Lipatov
    Department of Infectious Diseases Division of Virology, St Jude Children s Research Hospital, 332 North Lauderdale Street, Memphis, TN 38105 2794, USA
    J Gen Virol 86:1121-30. 2005
  4. ncbi request reprint A strategy for selective, CD4+ T cell-independent activation of virus-specific memory B cells for limiting dilution analysis
    Xiaofeng Li
    Department of Microbiology, M409 Walters Life Sciences Bldg, University of Tennessee, Knoxville, 37996, USA
    J Immunol Methods 313:110-8. 2006
  5. pmc Broad dispersion and lung localization of virus-specific memory B cells induced by influenza pneumonia
    Hye Mee Joo
    Department of Microbiology, University of Tennessee, Knoxville, TN 37996, USA
    Proc Natl Acad Sci U S A 105:3485-90. 2008

Research Grants

Collaborators

Detail Information

Publications5

  1. pmc An early CD4+ T cell-dependent immunoglobulin A response to influenza infection in the absence of key cognate T-B interactions
    Mark Y Sangster
    Department of Immunology, St Jude Children s Research Hospital, Memphis, TN 38105, USA
    J Exp Med 198:1011-21. 2003
    ..Our study demonstrates a CD4+ T cell-dependent, antiviral IgA response that is generated in the absence of B cell signaling via MHC II or CD40, and is restricted exclusively to virus-specific B cells...
  2. pmc Quantitative analysis of herpes simplex virus type 1-specific memory B cells generated by different routes of infection
    Daisy J Vanitha
    Department of Microbiology, M409 Walters Life Sciences Bldg, 1414 W Cumberland Ave, University of Tennessee, Knoxville, TN 37996, USA
    Virology 360:136-42. 2007
    ..Our findings indicate that the widespread dispersion of MBCs to lymphoid tissues throughout the body is largely independent of the route of infection, but may be influenced by tissue-specific factors...
  3. ncbi request reprint Pathogenesis of Hong Kong H5N1 influenza virus NS gene reassortants in mice: the role of cytokines and B- and T-cell responses
    Aleksandr S Lipatov
    Department of Infectious Diseases Division of Virology, St Jude Children s Research Hospital, 332 North Lauderdale Street, Memphis, TN 38105 2794, USA
    J Gen Virol 86:1121-30. 2005
    ..This cytokine imbalance is reminiscent of the clinical findings in two humans who died of H5N1/97 infection and may explain the unusual severity of the disease...
  4. ncbi request reprint A strategy for selective, CD4+ T cell-independent activation of virus-specific memory B cells for limiting dilution analysis
    Xiaofeng Li
    Department of Microbiology, M409 Walters Life Sciences Bldg, University of Tennessee, Knoxville, 37996, USA
    J Immunol Methods 313:110-8. 2006
    ..This strategy eliminates the influence of poorly defined T cell-associated factors on MBC frequency determinations...
  5. pmc Broad dispersion and lung localization of virus-specific memory B cells induced by influenza pneumonia
    Hye Mee Joo
    Department of Microbiology, University of Tennessee, Knoxville, TN 37996, USA
    Proc Natl Acad Sci U S A 105:3485-90. 2008
    ..Our findings provide insights into the pattern of B(Mem) dispersion, and emphasize the lung as a complex repository of immune memory after local infection...

Research Grants1

  1. Induction of influenza virus-specific memory B cells
    MARK SANGSTER; Fiscal Year: 2005
    ..In addition, the systems established could be used in many other ways to address mechanistic questions related to the generation and maintenance of B cell memory. ..