Teresa Sanchez

Summary

Affiliation: University of Connecticut Health Center
Country: USA

Publications

  1. ncbi request reprint Phosphorylation and action of the immunomodulator FTY720 inhibits vascular endothelial cell growth factor-induced vascular permeability
    Teresa Sanchez
    Center for Vascular Biology, Department of Cell Biology, University of Connecticut Health Center, 263 Farmington Avenue, Farmington, CT 06030 3501, USA
    J Biol Chem 278:47281-90. 2003
  2. ncbi request reprint Induction of vascular permeability by the sphingosine-1-phosphate receptor-2 (S1P2R) and its downstream effectors ROCK and PTEN
    Teresa Sanchez
    Center for Vascular Biology, Department of Cell Biology, University of Connecticut Health Center, 263 Farmington Ave, Farmington, CT 06030 3501, USA
    Arterioscler Thromb Vasc Biol 27:1312-8. 2007
  3. pmc S1P/S1P1 signaling stimulates cell migration and invasion in Wilms tumor
    Mei Hong Li
    Center for Vascular Biology, University of Connecticut Health Center, Farmington, CT 06030, USA
    Cancer Lett 276:171-9. 2009
  4. pmc PTEN as an effector in the signaling of antimigratory G protein-coupled receptor
    Teresa Sanchez
    Center for Vascular Biology, Department of Cell Biology, University of Connecticut Health Center, Farmington, CT 06030, USA
    Proc Natl Acad Sci U S A 102:4312-7. 2005
  5. pmc Essential role of sphingosine 1-phosphate receptor 2 in pathological angiogenesis of the mouse retina
    Athanasia Skoura
    Center for Vascular Biology, University of Connecticut Health Center, Farmington, Connecticut, USA
    J Clin Invest 117:2506-16. 2007
  6. pmc Induction of antiproliferative connective tissue growth factor expression in Wilms' tumor cells by sphingosine-1-phosphate receptor 2
    Mei Hong Li
    Center for Vascular Biology, University of Connecticut Health Center, Farmington, Connecticut, USA
    Mol Cancer Res 6:1649-56. 2008
  7. ncbi request reprint S1P/S1P2 signaling induces cyclooxygenase-2 expression in Wilms tumor
    Mei Hong Li
    Center for Vascular Biology, University of Connecticut Health Center, Farmington, Connecticut, USA
    J Urol 181:1347-52. 2009
  8. ncbi request reprint Structural and functional characteristics of S1P receptors
    Teresa Sanchez
    Department of Cell Biology, Center for Vascular Biology, University of Connecticut Health Center, 263 Farmington Avenue, Farmngton, Connecticut 06030 3501, USA
    J Cell Biochem 92:913-22. 2004
  9. ncbi request reprint Antagonism of sphingosine-1-phosphate receptors by FTY720 inhibits angiogenesis and tumor vascularization
    Kenneth LaMontagne
    Novartis Institutes for BioMedical Research, East Hanover, New Jersey, USA
    Cancer Res 66:221-31. 2006

Research Grants

  1. Sphingolipid Signaling in Endothelial Responses to Injury
    TERESA SANCHEZ GARCIA VAO; Fiscal Year: 2009

Collaborators

Detail Information

Publications9

  1. ncbi request reprint Phosphorylation and action of the immunomodulator FTY720 inhibits vascular endothelial cell growth factor-induced vascular permeability
    Teresa Sanchez
    Center for Vascular Biology, Department of Cell Biology, University of Connecticut Health Center, 263 Farmington Avenue, Farmington, CT 06030 3501, USA
    J Biol Chem 278:47281-90. 2003
    ....
  2. ncbi request reprint Induction of vascular permeability by the sphingosine-1-phosphate receptor-2 (S1P2R) and its downstream effectors ROCK and PTEN
    Teresa Sanchez
    Center for Vascular Biology, Department of Cell Biology, University of Connecticut Health Center, 263 Farmington Ave, Farmington, CT 06030 3501, USA
    Arterioscler Thromb Vasc Biol 27:1312-8. 2007
    ..However, cellular consequences of S1P2R signaling in the vascular cells are not well understood...
  3. pmc S1P/S1P1 signaling stimulates cell migration and invasion in Wilms tumor
    Mei Hong Li
    Center for Vascular Biology, University of Connecticut Health Center, Farmington, CT 06030, USA
    Cancer Lett 276:171-9. 2009
    ..In addition, S1P stimulated WiT49 cell invasion through S1P(1)/Gi signaling pathway. We consider that targeting S1P(1) may be a point of therapeutic intervention in Wilms tumor...
  4. pmc PTEN as an effector in the signaling of antimigratory G protein-coupled receptor
    Teresa Sanchez
    Center for Vascular Biology, Department of Cell Biology, University of Connecticut Health Center, Farmington, CT 06030, USA
    Proc Natl Acad Sci U S A 102:4312-7. 2005
    ..GPCR regulation of PTEN maybe a general mechanism in signaling events of cell migration and invasion...
  5. pmc Essential role of sphingosine 1-phosphate receptor 2 in pathological angiogenesis of the mouse retina
    Athanasia Skoura
    Center for Vascular Biology, University of Connecticut Health Center, Farmington, Connecticut, USA
    J Clin Invest 117:2506-16. 2007
    ..We propose that antagonism of the S1P2R may be a novel therapeutic approach for the prevention and/or treatment of pathologic ocular neovascularization...
  6. pmc Induction of antiproliferative connective tissue growth factor expression in Wilms' tumor cells by sphingosine-1-phosphate receptor 2
    Mei Hong Li
    Center for Vascular Biology, University of Connecticut Health Center, Farmington, Connecticut, USA
    Mol Cancer Res 6:1649-56. 2008
    ..In addition, overexpression of CTGF resulted in significant inhibition of WiT49 cell growth. Taken together, these data suggest that CTGF protein induced by S1P2 might act as a growth inhibitor in Wilms' tumor...
  7. ncbi request reprint S1P/S1P2 signaling induces cyclooxygenase-2 expression in Wilms tumor
    Mei Hong Li
    Center for Vascular Biology, University of Connecticut Health Center, Farmington, Connecticut, USA
    J Urol 181:1347-52. 2009
    ..Cyclooxygenase-2 has been reported to be ubiquitously expressed in Wilms tumor, the most common malignant renal tumor in children. However, to our knowledge the regulation mechanism of cyclooxygenase-2 expression remains unexplored...
  8. ncbi request reprint Structural and functional characteristics of S1P receptors
    Teresa Sanchez
    Department of Cell Biology, Center for Vascular Biology, University of Connecticut Health Center, 263 Farmington Avenue, Farmngton, Connecticut 06030 3501, USA
    J Cell Biochem 92:913-22. 2004
    ..Understanding the physiological role of these receptors and the basics of the ligand-receptor interaction will potentially provide new therapies to control a variety of diseases...
  9. ncbi request reprint Antagonism of sphingosine-1-phosphate receptors by FTY720 inhibits angiogenesis and tumor vascularization
    Kenneth LaMontagne
    Novartis Institutes for BioMedical Research, East Hanover, New Jersey, USA
    Cancer Res 66:221-31. 2006
    ..These data show that functional antagonism of vascular S1P receptors by FTY720 potently inhibits angiogenesis; therefore, this may provide a novel therapeutic approach for pathologic conditions with dysregulated angiogenesis...

Research Grants1

  1. Sphingolipid Signaling in Endothelial Responses to Injury
    TERESA SANCHEZ GARCIA VAO; Fiscal Year: 2009
    ..Answering these questions will help us to design new drugs that inhibit or activate S1P2R, which could be used as new therapies to alleviate the symptoms of atherosclerosis, diabetes or sepsis. ..