Muhammad T Salam

Summary

Affiliation: University of Southern California
Country: USA

Publications

  1. pmc Air pollution and birth weight in Connecticut and Massachusetts
    Muhammad Towhid Salam
    Environ Health Perspect 116:A106; author reply A106-7. 2008
  2. doi request reprint Asthma epigenetics
    Muhammad T Salam
    Department of Preventive Medicine, Keck School of Medicine, University of Southern California, 2001 N Soto Street, Mail Code 9237, Los Angeles, CA, 90033, USA
    Adv Exp Med Biol 795:183-99. 2014
  3. pmc Epigenetics and childhood asthma: current evidence and future research directions
    Muhammad T Salam
    Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA
    Epigenomics 4:415-29. 2012
  4. pmc Genetic and epigenetic variations in inducible nitric oxide synthase promoter, particulate pollution, and exhaled nitric oxide levels in children
    Muhammad T Salam
    Department of Preventive Medicine, University of Southern California Keck School of Medicine, Los Angeles, Calif 90089, USA
    J Allergy Clin Immunol 129:232-9.e1-7. 2012
  5. pmc Longitudinal effects of air pollution on exhaled nitric oxide: the Children's Health Study
    Kiros Berhane
    Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California, USA
    Occup Environ Med 71:507-13. 2014
  6. doi request reprint Role of inducible nitric oxide synthase in asthma risk and lung function growth during adolescence
    Talat Islam
    Department of Preventive Medicine, USC Keck School of Medicine, University of Southern California, 1540 Alcazar Street, CHP 236, Los Angeles, CA 90033, USA
    Thorax 65:139-45. 2010
  7. pmc Multiple-flow exhaled nitric oxide, allergy, and asthma in a population of older children
    William S Linn
    Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California 90089, USA
    Pediatr Pulmonol 48:885-96. 2013
  8. pmc Particulate matter, DNA methylation in nitric oxide synthase, and childhood respiratory disease
    Carrie V Breton
    Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California, USA
    Environ Health Perspect 120:1320-6. 2012
  9. pmc Residential traffic-related pollution exposures and exhaled nitric oxide in the children's health study
    Sandrah P Eckel
    University of Southern California, Los Angeles, California, USA
    Environ Health Perspect 119:1472-7. 2011
  10. pmc Genetic variation in the glutathione synthesis pathway, air pollution, and children's lung function growth
    Carrie V Breton
    Department of Preventive Medicine, USC Keck School of Medicine, 1540 Alcazar Street, CHP 236, Los Angeles, CA 90033, USA
    Am J Respir Crit Care Med 183:243-8. 2011

Detail Information

Publications36

  1. pmc Air pollution and birth weight in Connecticut and Massachusetts
    Muhammad Towhid Salam
    Environ Health Perspect 116:A106; author reply A106-7. 2008
  2. doi request reprint Asthma epigenetics
    Muhammad T Salam
    Department of Preventive Medicine, Keck School of Medicine, University of Southern California, 2001 N Soto Street, Mail Code 9237, Los Angeles, CA, 90033, USA
    Adv Exp Med Biol 795:183-99. 2014
    ..In this chapter, the influence of epigenetic variations on asthma pathophysiology, methodological concerns in conducting epigenetic research and future direction of asthma epigenetics research are discussed...
  3. pmc Epigenetics and childhood asthma: current evidence and future research directions
    Muhammad T Salam
    Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA
    Epigenomics 4:415-29. 2012
    ..This review provides a brief overview of epigenetic modifications, summarizes recent findings, and discusses some of the major methodological concerns that are relevant for asthma epigenetics...
  4. pmc Genetic and epigenetic variations in inducible nitric oxide synthase promoter, particulate pollution, and exhaled nitric oxide levels in children
    Muhammad T Salam
    Department of Preventive Medicine, University of Southern California Keck School of Medicine, Los Angeles, Calif 90089, USA
    J Allergy Clin Immunol 129:232-9.e1-7. 2012
    ..Short-term exposure to air pollution, haplotypes, and DNA methylation in the NOS2 promoter has been associated independently with iNOS expression, Feno levels, or both...
  5. pmc Longitudinal effects of air pollution on exhaled nitric oxide: the Children's Health Study
    Kiros Berhane
    Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California, USA
    Occup Environ Med 71:507-13. 2014
    ....
  6. doi request reprint Role of inducible nitric oxide synthase in asthma risk and lung function growth during adolescence
    Talat Islam
    Department of Preventive Medicine, USC Keck School of Medicine, University of Southern California, 1540 Alcazar Street, CHP 236, Los Angeles, CA 90033, USA
    Thorax 65:139-45. 2010
    ..Because nitrosative stress affects respiratory health, it was hypothesised that variants in NOS2A are associated with asthma incidence and lung function growth during adolescence...
  7. pmc Multiple-flow exhaled nitric oxide, allergy, and asthma in a population of older children
    William S Linn
    Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California 90089, USA
    Pediatr Pulmonol 48:885-96. 2013
    ..By contrast, CalvNO results were inconsistent across different extended NO regression models, and appeared more sensitive to small measurement artifacts...
  8. pmc Particulate matter, DNA methylation in nitric oxide synthase, and childhood respiratory disease
    Carrie V Breton
    Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California, USA
    Environ Health Perspect 120:1320-6. 2012
    ..Epigenetic regulation of nitric oxide synthase--the gene responsible for nitric oxide production--may be affected by air pollutants and contribute to the pathogenesis of asthma and wheeze...
  9. pmc Residential traffic-related pollution exposures and exhaled nitric oxide in the children's health study
    Sandrah P Eckel
    University of Southern California, Los Angeles, California, USA
    Environ Health Perspect 119:1472-7. 2011
    ..Existing studies have not yet provided conclusive evidence on the association of FeNO with traffic-related pollution (TRP)...
  10. pmc Genetic variation in the glutathione synthesis pathway, air pollution, and children's lung function growth
    Carrie V Breton
    Department of Preventive Medicine, USC Keck School of Medicine, 1540 Alcazar Street, CHP 236, Los Angeles, CA 90033, USA
    Am J Respir Crit Care Med 183:243-8. 2011
    ..Glutathione plays an important role in antioxidant and inflammatory processes in the lung. Alterations in glutathione metabolism are a central feature of several chronic lung diseases...
  11. pmc Roles of arginase variants, atopy, and ozone in childhood asthma
    Muhammad T Salam
    Department of Preventive Medicine, University of Southern California Keck School of Medicine, Los Angeles, Calif 90033, USA
    J Allergy Clin Immunol 123:596-602, 602.e1-8. 2009
    ..Arginases (encoded by ARG1 and ARG2 genes) might play an important role in asthma pathogenesis through effects on nitrosative stress. Arginase expression is upregulated in asthma and varies with T(H)2 cytokine levels and oxidative stress...
  12. pmc DNA methylation in the arginase-nitric oxide synthase pathway is associated with exhaled nitric oxide in children with asthma
    Carrie V Breton
    Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA
    Am J Respir Crit Care Med 184:191-7. 2011
    ..Genetic variation in arginase (ARG) and nitric oxide synthase (NOS) has been associated with exhaled nitric oxide (FeNO) levels in children. Little is known about whether epigenetic variation in these genes modulates FeNO...
  13. pmc Microsomal epoxide hydrolase, glutathione S-transferase P1, traffic and childhood asthma
    Muhammad T Salam
    Department of Preventive Medicine, University of Southern California Keck School of Medicine, Los Angeles, California 90033, USA
    Thorax 62:1050-7. 2007
    ..A study was undertaken to investigate associations of variants in EPHX1, GSTM1, GSTP1 and GSTT1 with asthma and the relationships between asthma, EPHX1 metabolic phenotypes and exposure to sources of PAHs...
  14. pmc Effects of in utero and childhood tobacco smoke exposure and beta2-adrenergic receptor genotype on childhood asthma and wheezing
    Chengwei Wang
    Department of Preventive Medicine, Keck School of Medicine, University of Southern California, 1540 Alcazar St, CHP 236, Los Angeles, CA 90033, USA
    Pediatrics 122:e107-14. 2008
    ....
  15. pmc Transforming growth factor- 1 C-509T polymorphism, oxidant stress, and early-onset childhood asthma
    Muhammad T Salam
    Department of Preventive Medicine, USC Keck School of Medicine, 1540 Alcazar Street, CHP 236, Los Angeles, CA 90033, USA
    Am J Respir Crit Care Med 176:1192-9. 2007
    ..Tobacco smoke and traffic emissions induce airway inflammation and modulate TGF-beta1 gene expression. We hypothesized that the effects of functional TGF-beta1 variants on asthma occurrence vary by these exposures...
  16. pmc Variation in the GST mu locus and tobacco smoke exposure as determinants of childhood lung function
    Carrie V Breton
    Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California, 90033 USA
    Am J Respir Crit Care Med 179:601-7. 2009
    ..The glutathione S-transferases (GSTs) are important detoxification enzymes...
  17. pmc Associations between ambient air pollution and Hypertensive Disorders of Pregnancy
    Zahra Mobasher
    Department of Preventive Medicine, University of Southern California, Keck School of Medicine, Los Angeles, CA, USA
    Environ Res 123:9-16. 2013
    ..Exposure to ambient air pollution is linked to adverse pregnancy outcomes. Previous reports examining the relationship between ambient air pollution and Hypertensive Disorders of Pregnancy have been inconsistent...
  18. pmc A protective role for early oral exposures in the etiology of young adult Hodgkin lymphoma
    Wendy Cozen
    Department of Preventive Medicine, Keck School of Medicine and Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, California, USA
    Blood 114:4014-20. 2009
    ..Our observations support a protective role for increased early oral exposure to the microbiome, suggesting that factors associated with increased Th2 and decreased Th1 cytokines are etiologically relevant to YAHL...
  19. pmc Spirometry effects on conventional and multiple flow exhaled nitric oxide in children
    Sandrah P Eckel
    Department of Preventive Medicine, University of Southern California, Los Angeles, CA, USA
    J Asthma 52:198-204. 2015
    ....
  20. pmc Heritability and role for the environment in DNA methylation in AXL receptor tyrosine kinase
    Carrie V Breton
    Departments of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA
    Epigenetics 6:895-8. 2011
    ..These results present compelling evidence that environmental exposure to tobacco smoke during pregnancy may alter DNA methylation levels in subtle but potentially important ways, and that these changes are persistent years after birth...
  21. pmc Birth outcomes and prenatal exposure to ozone, carbon monoxide, and particulate matter: results from the Children's Health Study
    Muhammad T Salam
    Department of Preventive Medicine, University of Southern California, Keck School of Medicine, Los Angeles, California 90033, USA
    Environ Health Perspect 113:1638-44. 2005
    ..1-42.2 g), but this association was reduced and not significant after adjusting for O3. In summary, O3 exposure during the second and third trimesters and CO exposure during the first trimester were associated with reduced birth weight...
  22. pmc Estimation of parameters in the two-compartment model for exhaled nitric oxide
    Sandrah P Eckel
    Department of Preventive Medicine, University of Southern California, Los Angeles, California, United States of America
    PLoS ONE 9:e85471. 2014
    ..We recommend a novel nonlinear least squares model with natural log transformation on both sides that produced estimators with good properties, satisfied model assumptions, and fit the Children's Health Study data well...
  23. pmc Interleukin-2, interleukin-12, and interferon-gamma levels and risk of young adult Hodgkin lymphoma
    Wendy Cozen
    Department of Preventive Medicine, Keck School of Medicine and Norris Comprehensive Cancer Center, University of Southern California, Los Angeles 90089 9175, USA
    Blood 111:3377-82. 2008
    ..8-fold (P=.03) increase in YAHL risk. Thus, both case-twins and their unaffected cotwins had a decreased ability to produce IL-12, which may contribute to YAHL susceptibility...
  24. ncbi request reprint Maternal fish consumption during pregnancy and risk of early childhood asthma
    Muhammad T Salam
    Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California 90033, USA
    J Asthma 42:513-8. 2005
    ..04; 95% CI = 1.18-3.51). Our results suggest that maternal oily fish intake during pregnancy may protect offspring from asthma; however, eating fish sticks during pregnancy may increase asthma risk in children...
  25. ncbi request reprint Recent evidence for adverse effects of residential proximity to traffic sources on asthma
    Muhammad T Salam
    Department of Preventive Medicine, University of Southern California Keck School of Medicine, Los Angeles, California 90033, USA
    Curr Opin Pulm Med 14:3-8. 2008
    ..In this review we have considered publications from 2006-2007 that examined the impact of residential traffic-related exposures on asthma occurrence and severity...
  26. pmc Ambient Air Pollutants Have Adverse Effects on Insulin and Glucose Homeostasis in Mexican Americans
    Zhanghua Chen
    Division of Environmental Health, Department of Preventive Medicine, Keck School of Medicine of the University of Southern California, Los Angeles, CA
    Diabetes Care 39:547-54. 2016
    ..The underlying physiological mechanisms have yet to be established. We hypothesized that air pollution adversely affects insulin sensitivity and secretion and serum lipid levels...
  27. pmc Inducible Nitric Oxide Synthase Promoter Haplotypes and Residential Traffic-Related Air Pollution Jointly Influence Exhaled Nitric Oxide Level in Children
    Muhammad T Salam
    Department of Preventive Medicine, University of Southern California Keck School of Medicine, Los Angeles, California, United States of America
    PLoS ONE 10:e0145363. 2015
    ....
  28. doi request reprint Extended exhaled nitric oxide analysis in field surveys of schoolchildren: a pilot test
    William S Linn
    Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California, USA
    Pediatr Pulmonol 44:1033-42. 2009
    ..Extended NO analysis holds promise for investigating environmental and genetic determinants of regional airway inflammatory states...
  29. doi request reprint Effects of Childhood Asthma on the Development of Obesity among School-aged Children
    Zhanghua Chen
    University of Southern California, Department of Preventive Medicine, Los Angeles, California, United States
    Am J Respir Crit Care Med . 2017
    ..Asthma and obesity often occur together in children. It is unknown whether asthma contributes to the childhood obesity epidemic...
  30. ncbi request reprint Maternal and grandmaternal smoking patterns are associated with early childhood asthma
    Yu Fen Li
    Department of Preventive Medicine, USC Keck School of Medicine, 1540 Alcazar St, CHP 236, Los Angeles, CA 90033, USA
    Chest 127:1232-41. 2005
    ..To investigate the associations of maternal and grandmaternal smoking before, during, and after pregnancy with childhood asthma...
  31. ncbi request reprint Mode of delivery is associated with asthma and allergy occurrences in children
    Muhammad T Salam
    Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles 90033, USA
    Ann Epidemiol 16:341-6. 2006
    ..In this study, we examined the associations between birth by cesarean section (C-section) and atopic disease occurrence in childhood...
  32. doi request reprint The significance of EphB4 and EphrinB2 expression and survival in head and neck squamous cell carcinoma
    Eric J Yavrouian
    Department of Otolaryngology Head and Neck Surgery, Keck School of Medicine, University of Southern California, Hoffman Medical Research 903, 2011 Zonal Ave, Los Angeles, CA 90033, USA
    Arch Otolaryngol Head Neck Surg 134:985-91. 2008
    ..To examine the expression of EphB4 and EphrinB2 in tumor tissue and surrounding normal tissue in patients with head and neck squamous cell carcinoma (HNSCC) and to evaluate its association with overall patient survival...
  33. ncbi request reprint Endogenous and exogenous sex steroid hormones and asthma and wheeze in young women
    Muhammad T Salam
    Department of Preventive Medicine, University of Southern California Keck School of Medicine, Los Angeles 90033, USA
    J Allergy Clin Immunol 117:1001-7. 2006
    ..Emerging evidence suggests that both endogenous and exogenous sex steroid hormones may influence the occurrence of asthma and wheeze among women...
  34. pmc Genetic Ancestry and Asthma and Rhinitis Occurrence in Hispanic Children: Findings from the Southern California Children's Health Study
    Muhammad T Salam
    Department of Preventive Medicine, University of Southern California, Keck School of Medicine, Los Angeles, California, United States of America Department of Psychiatry, Kern Medical Center, Bakersfield, California, United States of America
    PLoS ONE 10:e0135384. 2015
    ..We hypothesized that genetic ancestry is an important determinant of early-life asthma and rhinitis occurrence in Hispanic children independent of sociodemographic, acculturation and environmental factors...
  35. ncbi request reprint Associations between polymorphisms in the steroid 5-alpha reductase type II (SRD5A2) gene and benign prostatic hyperplasia and prostate cancer
    Muhammad T Salam
    Department of Preventive Medicine, University of Southern California, Los Angeles, Los Angeles, CA 90089, USA
    Urol Oncol 23:246-53. 2005
    ..03). Prostate cancer and BPH were not associated with the alanine-49 to threonine single nucleotide polymorphism and the (TA)n repeat. These results suggest that the SRD5A2 gene may play an important role in both BPH and prostate cancer...
  36. ncbi request reprint Interleukin-6-related genotypes, body mass index, and risk of multiple myeloma and plasmacytoma
    Wendy Cozen
    Department of Preventive Medicine, Keck School of Medicine, University of Southern California, 1441 Eastlake Avenue, MC 9175, Los Angeles, CA 90089 9175, USA
    Cancer Epidemiol Biomarkers Prev 15:2285-91. 2006
    ..These results suggest that IL-6 promoter genotypes may be associated with increased risk of plasma cell neoplasms...