Chieko Saito

Summary

Affiliation: University of Kansas Medical Center
Country: USA

Publications

  1. pmc Mechanism of protection by metallothionein against acetaminophen hepatotoxicity
    Chieko Saito
    Department of Pharmacology, Toxicology and Therapeutics, University of Kansas Medical Center, 3901 Rainbow Blvd, MS 1018, Kansas City, KS 66160, USA
    Toxicol Appl Pharmacol 242:182-90. 2010
  2. pmc c-Jun N-terminal kinase modulates oxidant stress and peroxynitrite formation independent of inducible nitric oxide synthase in acetaminophen hepatotoxicity
    Chieko Saito
    Department of Pharmacology, Toxicology and Therapeutics, University of Kansas Medical Center, Kansas City, KS 66160, USA
    Toxicol Appl Pharmacol 246:8-17. 2010
  3. pmc Novel mechanisms of protection against acetaminophen hepatotoxicity in mice by glutathione and N-acetylcysteine
    Chieko Saito
    Department of Pharmacology, University of Kansas Medical Center, Kansas City, KS 66160, USA
    Hepatology 51:246-54. 2010

Detail Information

Publications3

  1. pmc Mechanism of protection by metallothionein against acetaminophen hepatotoxicity
    Chieko Saito
    Department of Pharmacology, Toxicology and Therapeutics, University of Kansas Medical Center, 3901 Rainbow Blvd, MS 1018, Kansas City, KS 66160, USA
    Toxicol Appl Pharmacol 242:182-90. 2010
    ....
  2. pmc c-Jun N-terminal kinase modulates oxidant stress and peroxynitrite formation independent of inducible nitric oxide synthase in acetaminophen hepatotoxicity
    Chieko Saito
    Department of Pharmacology, Toxicology and Therapeutics, University of Kansas Medical Center, Kansas City, KS 66160, USA
    Toxicol Appl Pharmacol 246:8-17. 2010
    ....
  3. pmc Novel mechanisms of protection against acetaminophen hepatotoxicity in mice by glutathione and N-acetylcysteine
    Chieko Saito
    Department of Pharmacology, University of Kansas Medical Center, Kansas City, KS 66160, USA
    Hepatology 51:246-54. 2010
    ..However, increasing the dose of NAC improved the protective effect similar to GSH, suggesting that the amino acids not used for GSH synthesis were used as mitochondrial energy substrates...