J L R Rubenstein
Affiliation: University of California
- Model of autism: increased ratio of excitation/inhibition in key neural systemsJ L R Rubenstein
Nina Ireland Laboratory of Developmental Neurobiology, Center for Neurobiology and Psychiatry, Department of Psychiatry, University of California at San Francisco, San Francisco, CA 94143 0984, USA
Genes Brain Behav 2:255-67. 2003..Furthermore, the model suggests potential therapeutic interventions...
- Abnormal social behaviors in mice lacking Fgf17K Scearce-Levie
Gladstone Institute of Neurological Disease, San Francisco, CA 94158 2261, USA
Genes Brain Behav 7:344-54. 2008..Our findings show that Fgf17 is required for several complex social behaviors and suggest that disturbances in Fgf17 signaling may contribute to neuropsychiatric diseases that affect such behaviors...
- Neuronal production and precursor proliferation defects in the neocortex of mice with loss of function in the canonical Wnt signaling pathwayC J Zhou
Department of Neurology, UCSF Mission Bay, Box 2722, Rock Hall, 1550 Fourth Street, Room RH 348D, San Francisco, CA 94143 2722, USA
Neuroscience 142:1119-31. 2006..This analysis demonstrates that canonical Wnt signaling is required for a diverse array of developmental processes in the neocortex in addition to the previously known roles in regulating precursor proliferation and patterning...
- Coordinate regulation and synergistic actions of BMP4, SHH and FGF8 in the rostral prosencephalon regulate morphogenesis of the telencephalic and optic vesiclesY Ohkubo
Nina Ireland Laboratory of Developmental Neurobiology, Department of Psychiatry, LPPI, University of California, San Francisco, 401 Parnassus, P O Box 0984, San Francisco, CA 94143 0984, USA
Neuroscience 111:1-17. 2002....
- Autism as a disorder of neural information processing: directions for research and targets for therapyM K Belmonte
Autism Research Centre, Departments of Psychiatry and Experimental Psychology, University of Cambridge, Douglas House, 18b Trumpington Road, Cambridge CB2 2AH, UK
Mol Psychiatry 9:646-63. 2004....