Gordon Rubenfeld

Summary

Affiliation: University of Washington
Country: USA

Publications

  1. ncbi request reprint Can health care costs be reduced by limiting intensive care at the end of life?
    John M Luce
    Department of Medicine, University of California, San Francisco, San Francisco, California, USA
    Am J Respir Crit Care Med 165:750-4. 2002
  2. ncbi request reprint Incidence and outcomes of acute lung injury
    Gordon D Rubenfeld
    Division of Pulmonary and Critical Care Medicine, Harborview Medical Center, Seattle, WA 98104 2499, USA
    N Engl J Med 353:1685-93. 2005
  3. ncbi request reprint Hospital volume and the outcomes of mechanical ventilation
    Jeremy M Kahn
    Division of Pulmonary and Critical Care Medicine, University of Washington, Seattle 98104, USA
    N Engl J Med 355:41-50. 2006
  4. pmc Prediction of death and prolonged mechanical ventilation in acute lung injury
    Ognjen Gajic
    Mayo Clinic, 200 First Street SW, Rochester, Minnesota 55905, USA
    Crit Care 11:R53. 2007
  5. pmc Attending to the lightness of numbers: toward the understanding of critical care epidemiology
    Valdelis N Okamoto
    Respiratory Intensive Care Unit, Pulmonary Division, University of Sao Paulo, Sao Paulo, Brazil
    Crit Care 8:422-4. 2004
  6. ncbi request reprint End-of-life care in the intensive care unit: a research agenda
    G D Rubenfeld
    Division of Pulmonary and Critical Care Medicine, The Department of Medicine, University of Washington, Seattle, WA 98104 2499, USA
    Crit Care Med 29:2001-6. 2001
  7. ncbi request reprint Surveys: an introduction
    Gordon D Rubenfeld
    Division of Pulmonary and Critical Care Medicine, Box 359762, Harborview Medical Center, 325 9th Avenue, Seattle, WA 98104 2499, USA
    Respir Care 49:1181-5. 2004
  8. ncbi request reprint Translating clinical research into clinical practice in the intensive care unit: the central role of respiratory care
    Gordon D Rubenfeld
    Department of Pulmonary and Critical Care Medicine, Harborview Medical Center, Seattle WA 98104 2499, USA
    Respir Care 49:837-43. 2004
  9. ncbi request reprint Using computerized medical databases to measure and to improve the quality of intensive care
    Gordon D Rubenfeld
    Division of Pulmonary and Critical Care Medicine, Haborview Medical Center, Box 359762, 325 9th Ave, Seattle, WA 98104, USA
    J Crit Care 19:248-56. 2004
  10. ncbi request reprint Principles and practice of withdrawing life-sustaining treatments
    Gordon D Rubenfeld
    Harborview Medical Center, Division of Pulmonary and Critical Care Medicine, University of Washington, 325 Ninth Avenue, Seattle, WA 98104 2499, USA
    Crit Care Clin 20:435-51, ix. 2004

Collaborators

Detail Information

Publications95

  1. ncbi request reprint Can health care costs be reduced by limiting intensive care at the end of life?
    John M Luce
    Department of Medicine, University of California, San Francisco, San Francisco, California, USA
    Am J Respir Crit Care Med 165:750-4. 2002
  2. ncbi request reprint Incidence and outcomes of acute lung injury
    Gordon D Rubenfeld
    Division of Pulmonary and Critical Care Medicine, Harborview Medical Center, Seattle, WA 98104 2499, USA
    N Engl J Med 353:1685-93. 2005
    ..Despite recent advances in our understanding of the mechanism and treatment of acute lung injury, its incidence and outcomes in the United States have been unclear...
  3. ncbi request reprint Hospital volume and the outcomes of mechanical ventilation
    Jeremy M Kahn
    Division of Pulmonary and Critical Care Medicine, University of Washington, Seattle 98104, USA
    N Engl J Med 355:41-50. 2006
    ..The relationship between the number of patients admitted (hospital volume) and outcome among patients with critical illnesses is unknown...
  4. pmc Prediction of death and prolonged mechanical ventilation in acute lung injury
    Ognjen Gajic
    Mayo Clinic, 200 First Street SW, Rochester, Minnesota 55905, USA
    Crit Care 11:R53. 2007
    ..We aimed to identify risk factors for a combined end-point of death and/or prolonged ventilator dependence and developed an ALI-specific prediction model...
  5. pmc Attending to the lightness of numbers: toward the understanding of critical care epidemiology
    Valdelis N Okamoto
    Respiratory Intensive Care Unit, Pulmonary Division, University of Sao Paulo, Sao Paulo, Brazil
    Crit Care 8:422-4. 2004
    ....
  6. ncbi request reprint End-of-life care in the intensive care unit: a research agenda
    G D Rubenfeld
    Division of Pulmonary and Critical Care Medicine, The Department of Medicine, University of Washington, Seattle, WA 98104 2499, USA
    Crit Care Med 29:2001-6. 2001
    ..Although there have been consensus statements and review articles on end-of-life care in the ICU, there is limited evidence on which to base an assessment of best practices for providing high-quality end-of-life care in this setting...
  7. ncbi request reprint Surveys: an introduction
    Gordon D Rubenfeld
    Division of Pulmonary and Critical Care Medicine, Box 359762, Harborview Medical Center, 325 9th Avenue, Seattle, WA 98104 2499, USA
    Respir Care 49:1181-5. 2004
    ..In developing a valid survey instrument, it can be useful to adapt survey instruments that were developed by other researchers and to conduct extensive pilot-testing of your survey instrument...
  8. ncbi request reprint Translating clinical research into clinical practice in the intensive care unit: the central role of respiratory care
    Gordon D Rubenfeld
    Department of Pulmonary and Critical Care Medicine, Harborview Medical Center, Seattle WA 98104 2499, USA
    Respir Care 49:837-43. 2004
    ..Until recently the principal question facing intensivists was "Does this treatment work?" Though that question is still important, we now must address the same challenges other fields, notably cardiology, face in...
  9. ncbi request reprint Using computerized medical databases to measure and to improve the quality of intensive care
    Gordon D Rubenfeld
    Division of Pulmonary and Critical Care Medicine, Haborview Medical Center, Box 359762, 325 9th Ave, Seattle, WA 98104, USA
    J Crit Care 19:248-56. 2004
    ....
  10. ncbi request reprint Principles and practice of withdrawing life-sustaining treatments
    Gordon D Rubenfeld
    Harborview Medical Center, Division of Pulmonary and Critical Care Medicine, University of Washington, 325 Ninth Avenue, Seattle, WA 98104 2499, USA
    Crit Care Clin 20:435-51, ix. 2004
    ..Our hope is that adopting a more formal approach to this common procedure will improve the care of patients dying in intensive care units...
  11. ncbi request reprint Implementing effective ventilator practice at the bedside
    Gordon D Rubenfeld
    Division of Pulmonary and Critical Care Medicine, Harborview Medical Center, University of Washington, Seattle, Washington, USA
    Curr Opin Crit Care 10:33-9. 2004
    ..As the evidence base grows for effective critical care practice, so does the responsibility to translate practices that improve outcome from research journals to patients' bedsides. Strategies for doing this are presented in the review...
  12. ncbi request reprint Improving care for patients dying in the intensive care unit
    Gordon D Rubenfeld
    Division of Pulmonary and Critical Care Medicine, Harborview Medical Center, University of Washington, 325 Ninth Avenue, Seattle, WA 98104 2499, USA
    Clin Chest Med 24:763-73. 2003
    ..Practical approaches to improving the quality of end-of-life care exist and should be implemented...
  13. ncbi request reprint Epidemiology and outcomes of acute lung injury
    Gordon D Rubenfeld
    Division of Pulmonary and Critical Care Medicine, Harborview Medical Center, 325 Ninth Ave, Seattle WA 98104, USA
    Chest 131:554-62. 2007
    ....
  14. ncbi request reprint Interobserver variability in applying a radiographic definition for ARDS
    G D Rubenfeld
    Harborview Medical Center and the Division of Pulmonary and Critical Care Medicine, University of Washington, Seattle WA 98104, USA
    Chest 116:1347-53. 1999
    ..The accuracy or reliability of this consensus radiographic definition has not been evaluated, and no radiographic definition of ALI-ARDS has been evaluated by a large international group of experts...
  15. ncbi request reprint Understanding why we agree on the evidence but disagree on the medicine
    G D Rubenfeld
    Division of Pulmonary and Critical Care Medicine, Harborview Medical Center, Seattle, Washington 98104, USA
    Respir Care 46:1442-9. 2001
    ....
  16. ncbi request reprint Interventions to improve long-term outcomes after critical illness
    Gordon D Rubenfeld
    Interdepartmental Division of Critical Care Medicine, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada
    Curr Opin Crit Care 13:476-81. 2007
    ..The topic is complex because critical illness spans a number of diseases including spinal cord injury and myocardial infarction that have an extensive rehabilitation literature...
  17. pmc Beyond ethical dilemmas: improving the quality of end-of-life care in the intensive care unit
    Gordon D Rubenfeld
    Assistant Professor of Medicine, Division of Pulmonary and Critical Care Medicine, Harborview Medical Center, University of Washington, Seattle, Washington, USA
    Crit Care 7:11-2. 2003
  18. pmc Looking beyond 28-day all-cause mortality
    Gordon Rubenfeld
    Department of Medicine, University of Washington, Seattle, Washington, USA
    Crit Care 6:293-4. 2002
  19. doi request reprint Institutional and provider factors impeding access to trauma center care: an analysis of transfer practices in a regional trauma system
    David Gomez
    Division of General Surgery, Department of Surgery, University of Toronto, Toronto, Ontario, Canada
    J Trauma Acute Care Surg 73:1288-93. 2012
    ..In those who are transferred, significant delays have been described. The availability of specialists, imaging modalities, or critical care resources might significantly affect transfer practices...
  20. doi request reprint A population-based analysis of the discrepancy between potential and realized access to trauma center care
    David Gomez
    Keenan Research Centre in the Li Ka Shing Knowledge Institute of St Michael s Hospital, University of Toronto, Ontario, Canada
    Ann Surg 257:160-5. 2013
    ..To explore whether a discrepancy between the availability of trauma services (potential access) and trauma center utilization rates (realized access) exists, with the aim of informing strategies to improve access...
  21. pmc Effect of a fixed-ratio (1:1:1) transfusion protocol versus laboratory-results-guided transfusion in patients with severe trauma: a randomized feasibility trial
    Bartolomeu Nascimento
    Department of General Surgery, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ont
    CMAJ 185:E583-9. 2013
    ..We conducted a randomized controlled trial to assess the feasibility of a 1:1:1 transfusion protocol and its effect on mortality and complications among patients with severe trauma...
  22. ncbi request reprint Evaluation of a standardized order form for the withdrawal of life support in the intensive care unit
    Patsy D Treece
    Division of Pulmonary and Critical Care, Department of Medicine, Harborview Medical Center, University of Washington, Seattle, WA, USA
    Crit Care Med 32:1141-8. 2004
    ..We describe a quality improvement project implementing and evaluating a "withdrawal of life support order form" to improve quality of end-of-life care in the intensive care unit...
  23. doi request reprint Design and preliminary results of a pilot randomized controlled trial on a 1:1:1 transfusion strategy: the trauma formula-driven versus laboratory-guided study
    Bartolomeu Nascimento
    Department of Surgery, Tory Regional Trauma Centre, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada
    J Trauma 71:S418-26. 2011
    ..However, a randomized controlled trial on the topic is lacking. We report on the design and preliminary results of our ongoing randomized control pilot trial (ClinicalTrial.gov NCT00945542)...
  24. ncbi request reprint Integrating palliative and critical care: description of an intervention
    Patsy D Treece
    Harborview Medical Center, Division of Pulmonary and Critical Care, Department of Medicine, University of Washington, Seattle, Washington, USA
    Crit Care Med 34:S380-7. 2006
    ..Future reports will need to examine the ability of the interventions to improve outcomes of palliative care in the ICU...
  25. ncbi request reprint Hypercapnic acidosis and mortality in acute lung injury
    David A Kregenow
    Division of Pulmonary and Critical Care Medicine, Department of Medicine, University of Washington, Seattle, WA, USA
    Crit Care Med 34:1-7. 2006
    ..We tested the hypothesis that hypercapnic acidosis is associated with reduced mortality rate in patients with acute lung injury independent of changes in mechanical ventilation...
  26. ncbi request reprint Acute lung injury in patients with subarachnoid hemorrhage: incidence, risk factors, and outcome
    Jeremy M Kahn
    Division of Pulmonary and Critical Care Medicine, University of Washington, Seattle, WA, USA
    Crit Care Med 34:196-202. 2006
    ..Ventilator management was analyzed to determine the proportion of patients with subarachnoid hemorrhage and acute lung injury who a received a low-tidal volume ventilation strategy...
  27. ncbi request reprint Barriers to implementing the Leapfrog Group recommendations for intensivist physician staffing: a survey of intensive care unit directors
    Jeremy M Kahn
    Division of Pulmonary and Critical Care Medicine, Harborview Medical Center, University of Washington, Seattle, WA 98119, USA
    J Crit Care 22:97-103. 2007
    ..The purpose of this study was to examine the perception of the Leapfrog standards among ICU directors and determine the potential barriers to implementing these standards...
  28. ncbi request reprint Variations in rates of tracheostomy in the critically ill trauma patient
    Avery B Nathens
    Harborview Injury Prevention and Research Center, Seattle, WA, USA
    Crit Care Med 34:2919-24. 2006
    ..Thus, we set out explore the extent and potential sources of this variation among injured patients cared for in trauma centers in the United States...
  29. doi request reprint Improving clinical trials of long-term outcomes
    Gordon D Rubenfeld
    Department of Critical Care Medicine, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, Canada
    Crit Care Med 37:S112-6. 2009
    ..Those interested in this area should collaborate to build on the lessons from effective multidisciplinary programs developed to treat other diseases...
  30. ncbi request reprint Family satisfaction with family conferences about end-of-life care in the intensive care unit: increased proportion of family speech is associated with increased satisfaction
    Jonathan R McDonagh
    Department of Medicine, School of Medicine, University of Washington, Seattle, WA, USA
    Crit Care Med 32:1484-8. 2004
    ..The hypothesis of this analysis was that increased proportion of family speech during ICU family conferences would be associated with increased family satisfaction...
  31. doi request reprint A novel methodology to characterize interfacility transfer strategies in a trauma transfer network
    David Gomez
    From the Division of General Surgery, Department of Surgery D G, H T, A B N, University of Toronto, Ontario, Canada Sunnybrook Research Institute D G, B H, A A, H T, G R, A B N, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada Interdepartmental Division of Critical Care B H, A S A, J M S, J R, University of Toronto, Ontario, Canada Child Health Evaluative Sciences K L, The Hospital for Sick Children, Toronto, Ontario, Canada Department of Geography and Planning K L, University of Toronto, Ontario, Canada Ornge Transport Medicine R D M, H T, Mississauga, Ontario, Canada Division of Emergency Medicine, Department of Medicine R D M, University of Toronto, Ontario, Canada Toronto Western Research Institute J M S, Toronto Western Hospital, Toronto, Ontario, Canada and Department of Internal Medicine T J I, University of Michigan Medical School, Ann Arbor, Turkey
    J Trauma Acute Care Surg 81:658-65. 2016
    ..Selection of the receiving TC and the mode of interfacility transport both strongly influence total transfer time and are highly amenable to quality improvement initiatives...
  32. doi request reprint Research recruitment practices and critically ill patients. A multicenter, cross-sectional study (the Consent Study)
    Karen E A Burns
    Division of Critical Care Medicine, St Michael s Hospital, Toronto, Ontario, Canada
    Am J Respir Crit Care Med 187:1212-8. 2013
    ..Limited cross-sectional data exist to characterize the challenges of enrolling critically ill patients into research studies...
  33. pmc Long-term survival after hospitalization for community-acquired and healthcare-associated pneumonia
    Laura M Cecere
    Division of Pulmonary and Critical Care Medicine, University of Washington School of Medicine, Seattle, WA 98101, USA
    Respiration 79:128-36. 2010
    ..Elderly patients surviving community-acquired pneumonia (CAP) have subsequent increased mortality. However, little is known regarding long-term survival in younger adults or those with healthcare-associated pneumonia (HCAP)...
  34. ncbi request reprint Narcotic and benzodiazepine use after withdrawal of life support: association with time to death?
    Jeannie D Chan
    Department of Epidemiology, School of Public Health and Community Medicine, University of Washington, Seattle, USA
    Chest 126:286-93. 2004
    ..To determine whether the dose of narcotics and benzodiazepines is associated with length of time from mechanical ventilation withdrawal to death in the setting of withdrawal of life-sustaining treatment in the ICU...
  35. ncbi request reprint Transferring critically ill patients out of hospital improves the standardized mortality ratio: a simulation study
    Jeremy M Kahn
    Division of Pulmonary and Critical Care, Harborview Medical Center, University of Washington, Seattle WA, USA
    Chest 131:68-75. 2007
    ..We sought to quantify the effect of out-of-hospital transfers on the standardized mortality ratio (SMR), an outcome-based measure of ICU performance...
  36. ncbi request reprint The association between body mass index and clinical outcomes in acute lung injury
    Amy E Morris
    Division of Pulmonary and Critical Care Medicine, Department of Medicine, University of Washington School of Medicine, Harborview Medical Center, Mailbox 359762, 325 Ninth Ave, Seattle, WA 98104, USA
    Chest 131:342-8. 2007
    ..The association between body mass index (BMI) and outcomes in critically ill patients is unclear. Our objective was to determine the association between BMI and outcomes in a population-based cohort of patients with acute lung injury (ALI)...
  37. ncbi request reprint Studying communication about end-of-life care during the ICU family conference: development of a framework
    J Randall Curtis
    Division of Pulmonary and Critical Care Medicine, Department of Medicine, School of Medicine, University of Washington, Seattle, WA, USA
    J Crit Care 17:147-60. 2002
    ..The purpose of this study was to develop an understanding of the way this communication is currently conducted...
  38. pmc Effect of intensive care unit organizational model and structure on outcomes in patients with acute lung injury
    Miriam M Treggiari
    Department of Anesthesiology, Harborview Medical Center, University of Washington School of Medicine, 325 Ninth Avenue, Seattle, WA 98104, USA
    Am J Respir Crit Care Med 176:685-90. 2007
    ..Prior studies supported an association between intensive care unit (ICU) organizational model or staffing patterns and outcome in critically ill patients...
  39. ncbi request reprint Detecting Stenotrophomonas maltophilia does not reduce survival of patients with cystic fibrosis
    Christopher H Goss
    Division of Pulmonary and Critical Care Medicine, Department of Medicine, University of Washington Medical Center, Campus Box 356522, 1959 N E Pacific, Seattle, WA 98195, USA
    Am J Respir Crit Care Med 166:356-61. 2002
    ..89 (95% confidence interval, 0.75-1.05). Although patients with CF who acquire S. maltophilia have more advanced disease than those who do not acquire this organism, detection does not independently affect short-term survival (3 years)...
  40. ncbi request reprint Barriers to implementing protocol-based sepsis resuscitation in the emergency department--results of a national survey
    David J Carlbom
    Division of Pulmonary and Critical Care Medicine, Harborview Medical Center, University of Washington School of Medicine, Seattle, WA, USA
    Crit Care Med 35:2525-32. 2007
    ..To identify barriers to implementation of a written protocol for early goal-directed therapy for severe sepsis in the busiest emergency departments in the United States...
  41. ncbi request reprint The effects of leukoreduced blood transfusion on infection risk following injury: a randomized controlled trial
    Avery B Nathens
    Department of Surgery and the Harborview Injury Prevention and Research Center, University of Washington, Seattle, WA, USA
    Shock 26:342-7. 2006
    ..There was no effect on the rates of febrile episodes, mortality, length of stay, or severity of organ dysfunction...
  42. doi request reprint Practice variability in the assessment and treatment of critical illness-related corticosteroid insufficiency
    Veena Karir
    Department of Pharmacy, Harborview Medical Center, Box 359885, Seattle, WA 98104, USA
    J Crit Care 25:363.e9-363.e14. 2010
    ..Little is known about how published evidence regarding use of steroids in septic shock has been incorporated into clinical practice...
  43. doi request reprint Incidence and outcomes of pediatric acute lung injury
    Jerry J Zimmerman
    Division of Pediatric Critical Care Medicine, Seattle Children s Hospital, Harborview Medical Center, University of Washington, Seattle, Washington 98105 0371
    Pediatrics 124:87-95. 2009
    ..This population-based, prospective, cohort study was designed to determine the population incidence and outcomes of pediatric acute lung injury...
  44. doi request reprint Effects of leukoreduced blood on acute lung injury after trauma: a randomized controlled trial
    Timothy R Watkins
    Harborview Medical Center, Division of Pulmonary and Critical Care Medicine University of Washington, Seattle, WA, USA
    Crit Care Med 36:1493-9. 2008
    ..Residual leukocytes contaminating red cells are potential mediators of this syndrome. The goal of this trial was to test our hypothesis that prestorage leukoreduction of blood would reduce rates of posttraumatic lung injury...
  45. doi request reprint Predictors of hospital mortality in a population-based cohort of patients with acute lung injury
    Colin R Cooke
    Division of Pulmonary and Critical Care Medicine, Harborview Medical Center, University of Washington, Seattle, WA 98104, USA
    Crit Care Med 36:1412-20. 2008
    ..We sought to determine the predictors of mortality in a population-based cohort of patients with acute lung injury and to characterize the performance of current severity of illness scores in this population...
  46. pmc Cost-effectiveness of implementing low-tidal volume ventilation in patients with acute lung injury
    Colin R Cooke
    Division of Pulmonary and Critical Care Medicine, Harborview Medical Center, University of Washington, Seattle, WA 98104, USA
    Chest 136:79-88. 2009
    ..We sought to estimate the incremental clinical and economic outcomes associated with LPV and determined the maximum cost of a hypothetical intervention to improve adherence with LPV that remained cost-effective...
  47. pmc Cytomegalovirus reactivation in critically ill immunocompetent patients
    Ajit P Limaye
    Department of Laboratory Medicine, University of Washington Medical Center, 1959 NE Pacific St, Seattle, WA 98195 7110, USA
    JAMA 300:413-22. 2008
    ....
  48. pmc Intensive care unit-acquired neuromyopathy and corticosteroids in survivors of persistent ARDS
    Catherine L Hough
    Department of Medicine and The NHLBI ARDS Network, University of Washington, 325 Ninth Avenue, Mailstop 359762, Seattle, WA 98104, USA
    Intensive Care Med 35:63-8. 2009
    ..To determine the incidence and outcomes of intensive care unit-acquired neuromyopathy and to investigate the role of methylprednisolone in survivors of persistent acute lung injury...
  49. pmc The effect of an intensive care unit staffing model on tidal volume in patients with acute lung injury
    Colin R Cooke
    Division of Pulmonary and Critical Care Medicine, University of Washington School of Medicine, Harborview Medical Center, 325 9th Avenue, Box 359762, Seattle, Washington, 98104, USA
    Crit Care 12:R134. 2008
    ..We aimed to assess the effect of closed-model intensive care on evidence-based ventilatory practice in patients with acute lung injury (ALI)...
  50. ncbi request reprint Practice variation in respiratory therapy documentation during mechanical ventilation
    Saadia R Akhtar
    Division of Pulmonary and Critical Care Medicine, Harborview Medical Center, 325 Ninth Avenue, University of Washington, Seattle, WA 98104, USA
    Chest 124:2275-82. 2003
    ..One of the key factors in this communication is complete and accurate RT documentation of ventilator settings. Few studies have explored the quality and variability of this documentation...
  51. ncbi request reprint Changing pattern of ventilator settings in patients without acute lung injury: changes over 11 years in a single institution
    Phunsup Wongsurakiat
    Pulmonary and Critical Care Medicine Division, Harborview Medical Center, University of Washington, Seattle, WA, USA
    Chest 126:1281-91. 2004
    ....
  52. ncbi request reprint Clinical issues and research in respiratory failure from severe acute respiratory syndrome
    Mitchell M Levy
    Department of Medicine, Brown University Rhode Island Hospital, Providence, USA
    Am J Respir Crit Care Med 171:518-26. 2005
    ..The group recommended preparation for studies, including protocols, ethical considerations, Web-based registries, and data entry systems...
  53. ncbi request reprint Missed opportunities during family conferences about end-of-life care in the intensive care unit
    J Randall Curtis
    Division of Pulmonary and Critical Care Medicine, Harborview Medical Center, Box 359762, 325 Ninth Avenue, Seattle, WA 98104 2499, USA
    Am J Respir Crit Care Med 171:844-9. 2005
    ..Improved communication with family members of critically ill patients can decrease the prolongation of dying in the intensive care unit (ICU), but few data exist to guide the conduct of this communication...
  54. ncbi request reprint Causes and timing of death in patients with ARDS
    Renee D Stapleton
    Division of Pulmonary and Critical Care Medicine, Department of Medicine, Harborview Medical Center, University of Washington School of Medicine, Box 359762, 325 Ninth Ave, Seattle, WA 98104, USA
    Chest 128:525-32. 2005
    ..Since the early 1980s, case fatality of patients with ARDS has decreased, and explanations are unclear...
  55. ncbi request reprint Improving palliative care for patients in the intensive care unit
    J Randall Curtis
    Division of Pulmonary and Critical Care Medicine, Department of Medicine, University of Washington School of Medicine, Harborview Medical Center, Box 359761, 325 Ninth Avenue, Seattle, WA 98104 2499, USA
    J Palliat Med 8:840-54. 2005
  56. pmc Clinical trial participants compared with nonparticipants in cystic fibrosis
    Christopher H Goss
    University of Washington Medical Center, Campus Box 356522, 1959 N E Pacific, Seattle, WA 98195, USA
    Am J Respir Crit Care Med 173:98-104. 2006
    ..The randomized clinical trial has been an important tool for expanding our knowledge of disease. This study is the first to compare trial participants to the entire eligible population...
  57. ncbi request reprint Cost and incidence of social comorbidities in low-risk patients with community-acquired pneumonia admitted to a public hospital
    Christopher H Goss
    Division of Pulmonary and Critical Care Medicine, Department of Medicine, University of Washington School of Medicine, Medical Center Campus, Box 356522, 1959 N E Pacific, Seattle, WA 98195, USA
    Chest 124:2148-55. 2003
    ..A newly validated CAP outcomes prediction rule developed by Fine and colleagues has been advocated as a guide to hospitalization decisions...
  58. ncbi request reprint The effect of pregnancy on survival in women with cystic fibrosis
    Christopher H Goss
    Division of Pulmonary and Critical Care Medicine, Department of Medicine, University of Washington Medical Center, Seattle, WA 98195, USA
    Chest 124:1460-8. 2003
    ..Patients with cystic fibrosis (CF) are currently living to their fourth decade and are making reproductive decisions. Information concerning the reproductive health of women with CF has been limited to small or single-center studies...
  59. pmc Variation of arterial and central venous catheter use in United States intensive care units
    Hayley B Gershengorn
    From the Albert Einstein College of Medicine, Division of Pulmonary, Critical Care, and Sleep Medicine, Beth Israel Medical Center, New York, New York Current position Albert Einstein College of Medicine, Montefiore Medical Center, Bronx, New York H B G Section of Critical Care, University of Manitoba, Winnipeg, Manitoba, Canada A G Cerner Corporation, Vienna, Virginia A K Interdepartmental Division of Critical Care, University of Toronto, Toronto, Ontario, Canada D C S Department of Medicine, University of Toronto School of Medicine, Toronto, Ontario, Canada, and Department of Medicine, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada G R and Departments of Anesthesiology and Epidemiology, Columbia University, New York, New York H W
    Anesthesiology 120:650-64. 2014
    ..Arterial catheters (ACs) and central venous catheters (CVCs) are common in intensive care units (ICUs). Few data describe which patients receive these devices and whether variability in practice exists...
  60. pmc Implementation and impact of a translational research training program in pulmonary and critical care medicine
    Lynn M Schnapp
    Pulmonary and Critical Care Medicine, Harborview Medical Center, University of Washington, 325 Ninth Ave, Seattle, WA 98104, USA
    Chest 135:688-94. 2009
    ....
  61. ncbi request reprint Lung-protective ventilation strategies in acute lung injury
    Roy G Brower
    Department of Pulmonary and Critical Care Medicine, Johns Hopkins University, Baltimore, MD, USA
    Crit Care Med 31:S312-6. 2003
    ..To review the results of several randomized clinical trials of lung-protective ventilation strategies using conventional mechanical ventilators...
  62. ncbi request reprint Where do we go from here? One intensivist's perspective
    Gordon D Rubenfeld
    Division of Pulmonary and Critical Care Medicine, Department of Medicine, Harborview Medical Center, University of Washington, Seattle, Washington, USA
    Crit Care Med 34:S412-5. 2006
    ....
  63. ncbi request reprint Low tidal volume ventilation does not increase sedation use in patients with acute lung injury
    Jeremy M Kahn
    Division of Pulmonary and Critical Care Medicine, Harborview Medical Center, University of Washington, Seattle, WA, USA
    Crit Care Med 33:766-71. 2005
    ..We compared the doses and duration of sedatives and opioid analgesics in patients receiving low vs. traditional tidal volumes at our institution...
  64. ncbi request reprint Intrinsic positive end-expiratory pressure in Acute Respiratory Distress Syndrome (ARDS) Network subjects
    Catherine Lee Hough
    Division of Pulmonary and Critical Care Medicine, Department of Medicine at the University of Washington, Seattle, WA, USA
    Crit Care Med 33:527-32. 2005
    ....
  65. ncbi request reprint Barriers to providing lung-protective ventilation to patients with acute lung injury
    Gordon D Rubenfeld
    Pulmonary and Critical Care Medicine Division, Harborview Medical Center, University of Washington, Seattle, USA
    Crit Care Med 32:1289-93. 2004
    ..Our objective was to identify barriers to using lung-protective ventilation in patients with ALI/ARDS...
  66. doi request reprint Survival of the fittest: the hidden cost of undertriage of major trauma
    Barbara Haas
    Department of Surgery, University of Toronto, Toronto, Ontario, Canada
    J Am Coll Surg 211:804-11. 2010
    ..Previous analyses of undertriage focused only on survivors to trauma center care and were potentially subject to survivor bias. Using a novel population-based design, we evaluated the true mortality cost of undertriage...
  67. ncbi request reprint Effect of age on the development of ARDS in trauma patients
    Craig J Johnston
    Department of Medicine, Division of Pulmonary and Critical Care Medicine, University of Washington School of Medicine, Harborview Medical Center, Seattle, WA 98104, USA
    Chest 124:653-9. 2003
    ..The purpose of this study was to determine the independent effect of age on the risk of developing ARDS in patients with trauma...
  68. ncbi request reprint Comparison of scholarly productivity of general and subspecialty clinician-educators in internal medicine
    Robert R Kempainen
    Department of Internal Medicine, University of Washington School of Medicine, Seattle, Washington, USA
    Teach Learn Med 16:323-8. 2004
    ..There is concern that these criteria may be disadvantageous to clinician-educators in generalist fields relative to their specialist counterparts...
  69. pmc Global Variability in Reported Mortality for Critical Illness during the 2009-10 Influenza A(H1N1) Pandemic: A Systematic Review and Meta-Regression to Guide Reporting of Outcomes during Disease Outbreaks
    Abhijit Duggal
    Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, Ontario, Canada
    PLoS ONE 11:e0155044. 2016
    ..To determine how patient, healthcare system and study-specific factors influence reported mortality associated with critical illness during the 2009-2010 Influenza A (H1N1) pandemic...
  70. doi request reprint Gender-associated differences in access to trauma center care: A population-based analysis
    David Gomez
    Division of General Surgery, Department of Surgery, University of Toronto, Ontario
    Surgery 152:179-85. 2012
    ....
  71. ncbi request reprint Effect of acute lung injury and acute respiratory distress syndrome on outcome in critically ill trauma patients
    Miriam M Treggiari
    Department of Medicine, Harborview Medical Center, University of Wshington, Seattle, WA, USA
    Crit Care Med 32:327-31. 2004
    ..We estimated the independent impact of these conditions on mortality and cost, beyond the severity of injury with which they are correlated...
  72. ncbi request reprint Incidence of acute lung injury in the United States
    Christopher H Goss
    Division of Pulmonary and Critical Care Medicine, Department of Medicine, University of Washington Medical Center, Seattle, WA, USA
    Crit Care Med 31:1607-11. 2003
    ..We hypothesized that careful, prospective, protocol-driven case identification that included the milder hypoxemia criterion for ALI would yield incidence numbers greater than previously reported...
  73. doi request reprint Perceived barriers to therapeutic hypothermia for patients resuscitated from cardiac arrest: a qualitative study of emergency department and critical care workers
    Alina Toma
    Division of Emergency Medicine, Department of Medicine, University of Toronto, Toronto, ON, Canada
    Crit Care Med 38:504-9. 2010
    ..Despite scientific evidence to support therapeutic hypothermia for resuscitated cardiac arrest patients, it is inconsistently and at times inadequately used...
  74. ncbi request reprint The Postcardiac Arrest Consult Team: Impact on Hospital Care Processes for Out-of-Hospital Cardiac Arrest Patients
    Steven C Brooks
    1Department of Emergency Medicine, Queen s University, Kingston, ON, Canada 2Rescu, Li Ka Shing Knowledge Institute, St Michael s Hospital, Toronto, Ontario Canada 3Department of Critical Care Medicine, Sunnybrook Health Sciences Centre, Toronto, ON, Canada 4Interdepartmental Division of Critical Care Medicine, University of Toronto, Toronto, ON, Canada 5Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, ON 6Critical Care Department, St Michael s Hospital, Toronto, ON, Canada 7Department of Emergency Medicine, St Michael s Hospital, Toronto, ON, Canada 8Division of Emergency Medicine, Department of Medicine, University of Toronto, Toronto, ON, Canada 9Heart and Vascular Program, St Michael s Hospital, Toronto, ON, Canada 10Division of Cardiology, Department of Medicine, University of Toronto, Toronto, ON, Canada 11Department of Anesthesia, St Michael s Hospital, Toronto, ON, Canada 12Division of Cardiology, Imperial College London
    Crit Care Med 44:2037-2044. 2016
    ..To evaluate whether a Post-Arrest Consult Team improved care and outcomes for patients with out-of-hospital cardiac arrest...
  75. doi request reprint Prolonged mechanical ventilation in Canadian intensive care units: a national survey
    Louise Rose
    Lawrence S Bloomberg Faculty of Nursing, University of Toronto, Toronto, Ontario, Canada M5T 1P8 Provincial Centre of Weaning Excellence Prolonged Ventilation Weaning Centre, Toronto East General Hospital, Toronto, Ontario, Canada M4C 3E7 Mt Sinai Hospital, Toronto, Ontario, Canada M5G 1X5 Li Ka Shing Knowledge Institute, St Michael s Hospital, Toronto, Ontario, Canada M5B 1W8 Department of Critical Care, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada M4N 3M5 Sunnybrook Research Institute, Toronto, Ontario, Canada M4N 3M5 Electronic address
    J Crit Care 30:25-31. 2015
    ..We sought to describe prevalence and care practices for patients experiencing prolonged mechanical ventilation (PMV), defined as ventilation for 21 or more consecutive days and medical stability...
  76. pmc Emergency department length of stay for patients requiring mechanical ventilation: a prospective observational study
    Louise Rose
    Lawrence S, Bloomberg Faculty of Nursing, 155 College St, Rm 276, Toronto, ON, M5T IP8, Canada
    Scand J Trauma Resusc Emerg Med 20:30. 2012
    ..Additionally, we aimed to describe delivery and monitoring of ventilation in the ED...
  77. ncbi request reprint Measures, markers, and mediators: toward a staging system for clinical sepsis. A report of the Fifth Toronto Sepsis Roundtable, Toronto, Ontario, Canada, October 25-26, 2000
    John C Marshall
    Department of Surgery and Interdepartmental, Division of Critical Care, University of Toronto, Canada
    Crit Care Med 31:1560-7. 2003
    ..The evaluation of effective therapies has been hampered by limitations in our ability to characterize the process and to stratify patients into more homogeneous groups with respect to pathogenesis...
  78. pmc Clinical review: Fresh frozen plasma in massive bleedings - more questions than answers
    Bartolomeu Nascimento
    Transfusion Medicine, Sunnybrook Health Sciences Centre, University of Toronto, 2075 Bayview Ave, C160, Toronto, ON M4N 3M5, Canada
    Crit Care 14:202. 2010
    ....
  79. ncbi request reprint Epidemiology of acute lung injury
    Gordon D Rubenfeld
    Division of Pulmonary and Critical Care Medicine, Harborview Medical Center, University of Washington, Seattle, WA, USA
    Crit Care Med 31:S276-84. 2003
    ..To review the epidemiology of acute lung injury (ALI) with particular emphasis on its effect on public health...
  80. ncbi request reprint Translating evidence into practice in the intensive care unit: the need for a systems-based approach
    Jeremy M Kahn
    Division of Pulmonary and Critical Care Medicine, University of Washington, Seattle, WA 98104, USA
    J Crit Care 20:204-6. 2005
  81. doi request reprint Critical care and the global burden of critical illness in adults
    Neill K J Adhikari
    Interdepartmental Division of Critical Care, University of Toronto and Department of Critical Care Medicine, Sunnybrook Health Sciences Centre, Toronto, ON, Canada
    Lancet 376:1339-46. 2010
    ....
  82. pmc Age-, sex-, and race-based differences among patients enrolled versus not enrolled in acute lung injury clinical trials
    Colin R Cooke
    Division of Pulmonary and Critical Care Medicine, University of Michigan, Ann Arbor, MI, USA
    Crit Care Med 38:1450-7. 2010
    ..We sought to characterize the representation of racial and ethnic minorities, women, and older patients in clinical trials of patients with acute lung injury and to determine the reasons for nonenrollment...
  83. doi request reprint Update in critical care 2007
    Robert A Fowler
    Interdepartmental Division of Critical Care Medicine, University of Toronto, Toronto, Ontario, Canada
    Am J Respir Crit Care Med 177:808-19. 2008
  84. ncbi request reprint Proposed quality measures for palliative care in the critically ill: a consensus from the Robert Wood Johnson Foundation Critical Care Workgroup
    Richard A Mularski
    Center for Health Research, Kaiser Permanente Northwest, Portland, Oregon, USA
    Crit Care Med 34:S404-11. 2006
    ..The proposed measures are intended to stimulate further discussion, testing, and refinement for quality of care measurement and enhancement...
  85. pmc Year in review 2005: Critical Care - resource management
    Andre Carlos Kajdacsy Balla Amaral
    Critical Care Department, Hospital Sao Lucas, Brasilia, DF, Brazil
    Crit Care 10:215. 2006
    ..Future clinical work will rely heavily on these preclinical and laboratory data...
  86. ncbi request reprint Prioritizing the organization and management of intensive care services in the United States: the PrOMIS Conference
    Amber E Barnato
    Center for Research on Health Care, and the CRISMA Laboratory Clinical Research, Investigation, and Systems Modeling of Acute Illness, Department of Critical Care Medicine, University of Pittsburgh, Pittsburgh, PA, USA
    Crit Care Med 35:1003-11. 2007
    ..We sought to elicit the perceived problems and solutions to the delivery of critical care services from a broad set of U.S. stakeholders...
  87. ncbi request reprint Evidence-based ethics?
    Gordon D Rubenfeld
    Curr Opin Crit Care 11:598-9. 2005
  88. doi request reprint Perceptions of cost constraints, resource limitations, and rationing in United States intensive care units: results of a national survey
    Nicholas S Ward
    Division of Pulmonary Critical Care, Brown Medical School, Providence, RI, USA
    Crit Care Med 36:471-6. 2008
    ..To examine cost constraints, resource limitations, and rationing within U.S. intensive care units (ICUs) as perceived by ICU clinicians and the roles of ICU physician and nurse directors in resource allocation decisions...
  89. ncbi request reprint Use of intensive care at the end of life in the United States: an epidemiologic study
    Derek C Angus
    Department of Health Policy and Management, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA, USA
    Crit Care Med 32:638-43. 2004
    ..We sought to describe the use of ICU care at the end of life in the United States using hospital discharge data from 1999 for six states and the National Death Index...
  90. ncbi request reprint The epidemiologist in the intensive care unit
    Gordon D Rubenfeld
    Intensive Care Med 30:4-6. 2004
  91. ncbi request reprint Health status after critical illness: beyond descriptive studies
    Gordon D Rubenfeld
    Intensive Care Med 29:1626-7. 2003
  92. ncbi request reprint Is SARS just ARDS?
    Gordon D Rubenfeld
    JAMA 290:397-9. 2003
  93. doi request reprint Recommendations for end-of-life care in the intensive care unit: a consensus statement by the American College [corrected] of Critical Care Medicine
    Robert D Truog
    Harvard Medical School and Children s Hospital, Boston, MA, USA
    Crit Care Med 36:953-63. 2008
    ..S. perspective. They do not use an evidence grading system because most of the recommendations are based on ethical and legal principles that are not derived from empirically based evidence...
  94. ncbi request reprint Are intensivists safe?
    Gordon D Rubenfeld
    Ann Intern Med 148:877-9. 2008
  95. ncbi request reprint Critical care's great leap forward?
    Gordon D Rubenfeld
    Crit Care Med 34:1262-3. 2006