Michael D Rosenblum

Summary

Affiliation: University of California
Country: USA

Publications

  1. pmc Treating human autoimmunity: current practice and future prospects
    Michael D Rosenblum
    Department of Dermatology, University of California, San Francisco, San Francisco, CA 94115, USA
    Sci Transl Med 4:125sr1. 2012
  2. pmc Cutting edge: Self-antigen controls the balance between effector and regulatory T cells in peripheral tissues
    Iris K Gratz
    Department of Dermatology, University of California San Francisco, San Francisco, CA 94143
    J Immunol 192:1351-5. 2014
  3. pmc Response to self antigen imprints regulatory memory in tissues
    Michael D Rosenblum
    Department of Dermatology, University of California San Francisco, San Francisco, California 94115, USA
    Nature 480:538-42. 2011
  4. doi request reprint The life of regulatory T cells
    Iris K Gratz
    Department of Dermatology, University of California San Francisco School of Medicine, San Francisco, CA 94143 0511, USA
    Ann N Y Acad Sci 1283:8-12. 2013
  5. pmc Cutting Edge: memory regulatory t cells require IL-7 and not IL-2 for their maintenance in peripheral tissues
    Iris K Gratz
    Department of Dermatology, University of California San Francisco, San Francisco, CA 94143, USA
    J Immunol 190:4483-7. 2013
  6. pmc Opposing functions of IL-2 and IL-7 in the regulation of immune responses
    Shoshana D Katzman
    Department of Pathology, University of California San Francisco, San Francisco, CA 94143 0511, USA
    Cytokine 56:116-21. 2011
  7. pmc A Wave of Regulatory T Cells into Neonatal Skin Mediates Tolerance to Commensal Microbes
    Tiffany C Scharschmidt
    Department of Dermatology, University of California, San Francisco, San Francisco, CA 94143, USA
    Immunity 43:1011-21. 2015
  8. doi request reprint Regulatory T cell memory
    Michael D Rosenblum
    Department of Dermatology, University of California San Francisco, San Francisco, California 94143, USA
    Nat Rev Immunol 16:90-101. 2016
  9. pmc The distribution of cutaneous metastases correlates with local immunologic milieu
    Joshua M Schulman
    Department of Dermatology, University of California, San Francisco, California Department of Pathology, University of California, San Francisco, California
    J Am Acad Dermatol 74:470-6. 2016

Collaborators

  • Ann Marshak-Rothstein
  • Michael Otto
  • Sing Sing Way
  • James J Moon
  • Hans Dooms
  • Abul K Abbas
  • Iris K Gratz
  • Hong An Truong
  • Joshua M Schulman
  • Mariela L Pauli
  • Tiffany C Scharschmidt
  • Megan M Maurano
  • Jonathan S Paw
  • Shoshana D Katzman
  • Timothy H McCalmont
  • Roberto Sanchez Rodriguez
  • Keyon Taravati
  • Uk Sok Shin
  • Isaac M Neuhaus
  • Jan Liese
  • Kimberly S Vasquez
  • Audrey Nosbaum
  • Michael A Fischbach
  • Sofia V Gearty
  • Karim Lee
  • Sara Hsin Yi Yang
  • Sara H Isakson
  • Katrina K Hoyer

Detail Information

Publications9

  1. pmc Treating human autoimmunity: current practice and future prospects
    Michael D Rosenblum
    Department of Dermatology, University of California, San Francisco, San Francisco, CA 94115, USA
    Sci Transl Med 4:125sr1. 2012
    ..This review discusses these advances as well as the challenges that must be overcome to target these therapies to patients suffering from autoimmune disease while avoiding the pitfalls of general immunosuppression...
  2. pmc Cutting edge: Self-antigen controls the balance between effector and regulatory T cells in peripheral tissues
    Iris K Gratz
    Department of Dermatology, University of California San Francisco, San Francisco, CA 94143
    J Immunol 192:1351-5. 2014
    ..Our studies reveal a crucial role for Ag in maintaining appropriate ratios of Ag-specific Teffs to Tregs in tissues. ..
  3. pmc Response to self antigen imprints regulatory memory in tissues
    Michael D Rosenblum
    Department of Dermatology, University of California San Francisco, San Francisco, California 94115, USA
    Nature 480:538-42. 2011
    ..These findings provide a framework for understanding how T(reg) cells respond when exposed to self antigen in peripheral tissues and offer mechanistic insight into how tissues regulate autoimmunity...
  4. doi request reprint The life of regulatory T cells
    Iris K Gratz
    Department of Dermatology, University of California San Francisco School of Medicine, San Francisco, CA 94143 0511, USA
    Ann N Y Acad Sci 1283:8-12. 2013
    ....
  5. pmc Cutting Edge: memory regulatory t cells require IL-7 and not IL-2 for their maintenance in peripheral tissues
    Iris K Gratz
    Department of Dermatology, University of California San Francisco, San Francisco, CA 94143, USA
    J Immunol 190:4483-7. 2013
    ..Conversely, IL-7 is essential for maintaining mTregs in skin in the steady state. These results elucidate the fundamental biology of mTregs and show that IL-7 plays an important role in their survival in skin...
  6. pmc Opposing functions of IL-2 and IL-7 in the regulation of immune responses
    Shoshana D Katzman
    Department of Pathology, University of California San Francisco, San Francisco, CA 94143 0511, USA
    Cytokine 56:116-21. 2011
    ..Here we discuss the opposing functions of two members of the common receptor gamma chain (╬│c) cytokines, IL-2 and IL-7 in the generation and regulation of immune responses in vivo...
  7. pmc A Wave of Regulatory T Cells into Neonatal Skin Mediates Tolerance to Commensal Microbes
    Tiffany C Scharschmidt
    Department of Dermatology, University of California, San Francisco, San Francisco, CA 94143, USA
    Immunity 43:1011-21. 2015
    ..This suggests that the cutaneous microbiome composition in neonatal life is crucial in shaping adaptive immune responses to commensals, and disrupting these interactions might have enduring health implications. ..
  8. doi request reprint Regulatory T cell memory
    Michael D Rosenblum
    Department of Dermatology, University of California San Francisco, San Francisco, California 94143, USA
    Nat Rev Immunol 16:90-101. 2016
    ..In addition, we discuss emerging evidence for regulatory T cell memory in humans and key unanswered questions in this rapidly evolving field. ..
  9. pmc The distribution of cutaneous metastases correlates with local immunologic milieu
    Joshua M Schulman
    Department of Dermatology, University of California, San Francisco, California Department of Pathology, University of California, San Francisco, California
    J Am Acad Dermatol 74:470-6. 2016
    ..Metastases to the skin are found with increased frequency at certain sites, such as the scalp, but the biological factors that influence this distribution are not understood...