Claus G Roehrborn

Summary

Affiliation: University of Texas Southwestern Medical Center
Country: USA

Publications

  1. ncbi request reprint Open to debate. The motion: prevention of prostate cancer with a 5alpha-reductase inhibitor is feasible
    Claus G Roehrborn
    Department of Urology, University of Texas Southwestern Medical Center at Dallas, Dallas, TX, USA
    Eur Urol 49:396-400. 2006
  2. doi request reprint Predictive value of the differential expression of the urokinase plasminogen activation axis in radical prostatectomy patients
    Amit Gupta
    Department of Urology, University of Texas Southwestern Medical Center, Dallas, Texas 75390 9110, USA
    Eur Urol 55:1124-33. 2009
  3. doi request reprint The effects of combination therapy with dutasteride and tamsulosin on clinical outcomes in men with symptomatic benign prostatic hyperplasia: 4-year results from the CombAT study
    Claus G Roehrborn
    Department of Urology, UT Southwestern Medical Center, Dallas, Texas 75390 9110, USA
    Eur Urol 57:123-31. 2010
  4. doi request reprint Pre-treatment biomarker levels improve the accuracy of post-prostatectomy nomogram for prediction of biochemical recurrence
    Robert S Svatek
    Department of Urology, University of Texas Southwestern Medical Centre, 1515 Holcombe Blvd, Houston, TX 77030, USA
    Prostate 69:886-94. 2009
  5. doi request reprint Effects of serum PSA on efficacy of tolterodine extended release with or without tamsulosin in men with LUTS, including OAB
    Claus G Roehrborn
    Department of Urology, University of Texas Southwestern, Medical Center at Dallas, Texas 75390 9110, USA
    Urology 72:1061-7; discussion 1067. 2008
  6. doi request reprint Use of preoperative plasma endoglin for prediction of lymph node metastasis in patients with clinically localized prostate cancer
    Jose A Karam
    Department of Urology, The University of Texas Southwestern Medical Center, Dallas, Texas 75390 9110, USA
    Clin Cancer Res 14:1418-22. 2008
  7. ncbi request reprint Plasminogen activation inhibitor-1 improves the predictive accuracy of prostate cancer nomograms
    Shahrokh F Shariat
    Department of Urology, University of Texas Southwestern Medical Center, Dallas, Texas 75390 9110, USA
    J Urol 178:1229-36; discussion 1236-7. 2007
  8. ncbi request reprint Caveolin-1 overexpression is associated with aggressive prostate cancer recurrence
    Jose A Karam
    Department of Urology, University of Texas Southwestern Medical Center, Dallas, TX 75390 9110, USA
    Prostate 67:614-22. 2007
  9. doi request reprint Development of a highly accurate nomogram for prediction of the need for exploration in patients with renal trauma
    Shahrokh F Shariat
    Department of Urology, University of Texas Southwestern Medical Center, Dallas, Texas, USA
    J Trauma 64:1451-8. 2008
  10. ncbi request reprint Pre-operative percent free PSA predicts clinical outcomes in patients treated with radical prostatectomy with total PSA levels below 10 ng/ml
    Shahrokh F Shariat
    Department of Urology, The University of Texas Southwestern Medical Center at Dallas, TX 75390 9110, USA
    Eur Urol 49:293-302. 2006

Detail Information

Publications95

  1. ncbi request reprint Open to debate. The motion: prevention of prostate cancer with a 5alpha-reductase inhibitor is feasible
    Claus G Roehrborn
    Department of Urology, University of Texas Southwestern Medical Center at Dallas, Dallas, TX, USA
    Eur Urol 49:396-400. 2006
  2. doi request reprint Predictive value of the differential expression of the urokinase plasminogen activation axis in radical prostatectomy patients
    Amit Gupta
    Department of Urology, University of Texas Southwestern Medical Center, Dallas, Texas 75390 9110, USA
    Eur Urol 55:1124-33. 2009
    ..This axis is involved in cell proliferation, angiogenesis, extracellular matrix degradation, invasion, and metastases...
  3. doi request reprint The effects of combination therapy with dutasteride and tamsulosin on clinical outcomes in men with symptomatic benign prostatic hyperplasia: 4-year results from the CombAT study
    Claus G Roehrborn
    Department of Urology, UT Southwestern Medical Center, Dallas, Texas 75390 9110, USA
    Eur Urol 57:123-31. 2010
    ....
  4. doi request reprint Pre-treatment biomarker levels improve the accuracy of post-prostatectomy nomogram for prediction of biochemical recurrence
    Robert S Svatek
    Department of Urology, University of Texas Southwestern Medical Centre, 1515 Holcombe Blvd, Houston, TX 77030, USA
    Prostate 69:886-94. 2009
    ..We tested the ability of several pre-operative blood-based biomarkers to enhance the accuracy of standard post-operative features for the prediction of biochemical recurrence (BCR) after radical prostatectomy (RP)...
  5. doi request reprint Effects of serum PSA on efficacy of tolterodine extended release with or without tamsulosin in men with LUTS, including OAB
    Claus G Roehrborn
    Department of Urology, University of Texas Southwestern, Medical Center at Dallas, Texas 75390 9110, USA
    Urology 72:1061-7; discussion 1067. 2008
    ..To evaluate the efficacy of tolterodine extended release (ER), tamsulosin, and tolterodine ER plus tamsulosin in men with symptoms of overactive bladder and benign prostatic hyperplasia stratified by prostate-specific antigen (PSA) level...
  6. doi request reprint Use of preoperative plasma endoglin for prediction of lymph node metastasis in patients with clinically localized prostate cancer
    Jose A Karam
    Department of Urology, The University of Texas Southwestern Medical Center, Dallas, Texas 75390 9110, USA
    Clin Cancer Res 14:1418-22. 2008
    ..The aim of the study was to evaluate whether preoperative plasma endoglin improves the prediction of lymph node metastases in patients with clinically localized prostate cancer...
  7. ncbi request reprint Plasminogen activation inhibitor-1 improves the predictive accuracy of prostate cancer nomograms
    Shahrokh F Shariat
    Department of Urology, University of Texas Southwestern Medical Center, Dallas, Texas 75390 9110, USA
    J Urol 178:1229-36; discussion 1236-7. 2007
    ....
  8. ncbi request reprint Caveolin-1 overexpression is associated with aggressive prostate cancer recurrence
    Jose A Karam
    Department of Urology, University of Texas Southwestern Medical Center, Dallas, TX 75390 9110, USA
    Prostate 67:614-22. 2007
    ....
  9. doi request reprint Development of a highly accurate nomogram for prediction of the need for exploration in patients with renal trauma
    Shahrokh F Shariat
    Department of Urology, University of Texas Southwestern Medical Center, Dallas, Texas, USA
    J Trauma 64:1451-8. 2008
    ..To develop and validate a nomogram for predicting the need for renal exploration after renal trauma...
  10. ncbi request reprint Pre-operative percent free PSA predicts clinical outcomes in patients treated with radical prostatectomy with total PSA levels below 10 ng/ml
    Shahrokh F Shariat
    Department of Urology, The University of Texas Southwestern Medical Center at Dallas, TX 75390 9110, USA
    Eur Urol 49:293-302. 2006
    ..To evaluate the association of total prostate specific antigen (T-PSA) and percent free PSA (%F-PSA) with prostate cancer outcomes in patients treated with radical prostatectomy (RP)...
  11. doi request reprint Extended-release tolterodine with or without tamsulosin in men with lower urinary tract symptoms and overactive bladder: effects on urinary symptoms assessed by the International Prostate Symptom Score
    Steven A Kaplan
    Department of Urology, Weill Cornell Medical College, New York, NY 10021, USA
    BJU Int 102:1133-9. 2008
    ....
  12. ncbi request reprint The effects of dutasteride, tamsulosin and combination therapy on lower urinary tract symptoms in men with benign prostatic hyperplasia and prostatic enlargement: 2-year results from the CombAT study
    Claus G Roehrborn
    Department of Urology, University of Texas Southwestern Medical Center, Dallas, Texas, USA
    J Urol 179:616-21; discussion 621. 2008
    ..We report preplanned 2-year analyses...
  13. doi request reprint Tolterodine extended release with or without tamsulosin in men with lower urinary tract symptoms including overactive bladder symptoms: effects of prostate size
    Claus G Roehrborn
    Department of Urology, University of Texas Southwestern Medical Center at Dallas, Dallas, TX 75390 9110, USA
    Eur Urol 55:472-9. 2009
    ..Some men with lower urinary tract symptoms (LUTS) including overactive bladder (OAB) symptoms may benefit from antimuscarinic therapy, with or without an alpha-adrenergic antagonist...
  14. ncbi request reprint Predictive value of primary Gleason pattern 4 in patients with Gleason score 7 tumours treated with radical prostatectomy
    Seyed M Khoddami
    Department of Urology, The University of Texas South Western Medical Center, Dallas, USA
    BJU Int 94:42-6. 2004
    ..To examine whether Gleason score (GS) 3 + 4 and 4 + 3 cancers at radical prostatectomy behave differently and whether this behaviour is independently associated with prostate cancer outcome...
  15. ncbi request reprint Use of combined apoptosis biomarkers for prediction of bladder cancer recurrence and mortality after radical cystectomy
    Jose A Karam
    Department of Urology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA
    Lancet Oncol 8:128-36. 2007
    ....
  16. doi request reprint Preoperative plasma endoglin levels predict biochemical progression after radical prostatectomy
    Robert S Svatek
    Department of Urology, The University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390 9110, USA
    Clin Cancer Res 14:3362-6. 2008
    ..The aim of this study was to evaluate the association of preoperative plasma endoglin levels with established clinical and pathologic features of prostate cancer and disease progression after radical prostatectomy...
  17. ncbi request reprint Prostate cancer disease-free survival after radical retropubic prostatectomy in patients older than 70 years compared to younger cohorts
    Bahaa S Malaeb
    Department of Urology, University of Minnesota, Minneapolis, MN 55455, USA
    Urol Oncol 25:291-7. 2007
    ..To evaluate the feasibility of radical retropubic prostatectomy (RRP) as an option for treating men older than 70 years with organ confined prostate cancer and to compare biochemical progression-free survival with younger cohorts...
  18. ncbi request reprint Variability in the performance of nuclear matrix protein 22 for the detection of bladder cancer
    Shahrokh F Shariat
    Department of Urology, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390, USA
    J Urol 176:919-26; discussion 926. 2006
    ..We assessed variability in the diagnostic performance of NMP22 for detecting recurrence and progression in patients with Ta, T1, and/or CIS transitional cell carcinoma of the bladder in a large international cohort...
  19. doi request reprint Predictive value of plasma hepatocyte growth factor/scatter factor levels in patients with clinically localized prostate cancer
    Amit Gupta
    Department of Urology, The University of Texas Southwestern Medical Center, Dallas, Texas 75390 9110, USA
    Clin Cancer Res 14:7385-90. 2008
    ..We assessed whether preoperative plasma levels of HGF can enhance the accuracy of standard models for predicting pathologic features and clinical outcomes...
  20. doi request reprint The influence of baseline parameters on changes in international prostate symptom score with dutasteride, tamsulosin, and combination therapy among men with symptomatic benign prostatic hyperplasia and an enlarged prostate: 2-year data from the CombAT stu
    Claus G Roehrborn
    Department of Urology, UT Southwestern Medical Center, Dallas, TX 75390 9110, USA
    Eur Urol 55:461-71. 2009
    ..Knowledge of baseline factors that influence outcomes for men with benign prostatic hyperplasia (BPH) receiving medical therapy may help to improve outcomes and cost effectiveness...
  21. ncbi request reprint Tolterodine and tamsulosin for treatment of men with lower urinary tract symptoms and overactive bladder: a randomized controlled trial
    Steven A Kaplan
    Department of Urology, Weill Cornell Medical College, New York, NY 10021, USA
    JAMA 296:2319-28. 2006
    ..Men with overactive bladder and other lower urinary tract symptoms may not respond to monotherapy with antimuscarinic agents or alpha-receptor antagonists...
  22. doi request reprint The influence of body mass index on the cost of radical prostatectomy for prostate cancer
    Christian Bolenz
    Departments of Urology, University of Texas Southwestern Medical Center at Dallas, TX, USA
    BJU Int 106:1188-93. 2010
    ..to evaluate the impact of obesity on the costs of robotic-assisted (RALP), laparoscopic (LRP) and open retropubic radical prostatectomy (RRP)...
  23. ncbi request reprint The percent of biopsy cores positive for cancer is a predictor of advanced pathological stage and poor clinical outcomes in patients treated with radical prostatectomy
    Yair Lotan
    Departments of Urology and Pathology, University of Texas Southwestern Medical Center at Dallas, Dallas, Texas 75390 9110, USA
    J Urol 171:2209-14. 2004
    ..We examined if the percent of positive biopsies is associated with features of biologically aggressive prostate cancer, biochemical progression and development of distant metastases in patients undergoing radical prostatectomy (RP)...
  24. doi request reprint Effect of dutasteride on prostate biopsy rates and the diagnosis of prostate cancer in men with lower urinary tract symptoms and enlarged prostates in the Combination of Avodart and Tamsulosin trial
    Claus G Roehrborn
    Department of Urology, UT Southwestern Medical Center, Dallas, TX, USA
    Eur Urol 59:244-9. 2011
    ..A 23% relative risk reduction (RRR) in prostate cancer (PCa) was shown in men receiving dutasteride in the 4-yr Reduction by Dutasteride of Prostate Cancer Events study, in whom biopsies were protocol dependent...
  25. ncbi request reprint Prognostic value of syndecan-1 expression in patients treated with radical prostatectomy
    Shahrokh F Shariat
    Department of Urology, University of Texas Southwestern Medical Center, Dallas, TX 75390 9110, USA
    BJU Int 101:232-7. 2008
    ....
  26. doi request reprint The effect of the approach to radical prostatectomy on the profitability of hospitals and surgeons
    Yair Lotan
    Department of Urology, University of Texas Southwestern Medical Center, Dallas, TX, USA
    BJU Int 105:1531-5. 2010
    ....
  27. ncbi request reprint Role of urinary cathepsin B and L in the detection of bladder urothelial cell carcinoma
    Robert S Svatek
    Department of Urology, University of Texas Southwestern Medical Center, Dallas, Texas, USA
    J Urol 179:478-84; discussion 484. 2008
    ..We tested the hypothesis that urinary cathepsin B and L are associated with bladder cancer recurrence and invasiveness in patients with a history of nonmuscle invasive urothelial carcinoma of the bladder...
  28. ncbi request reprint Preoperative plasma HER2 and epidermal growth factor receptor for staging and prognostication in patients with clinically localized prostate cancer
    Shahrokh F Shariat
    Department of Urology, University of Texas Southwestern Medical Center at Dallas, Dallas, Texas 75390 9110, USA
    Clin Cancer Res 13:5377-84. 2007
    ..We tested the hypothesis that plasma levels of HER2 and/or EGFR are associated with prostate cancer stage and prognosis in patients with clinically localized disease...
  29. doi request reprint Tadalafil administered once daily for lower urinary tract symptoms secondary to benign prostatic hyperplasia: a dose finding study
    Claus G Roehrborn
    Department of Urology, University of Texas Southwestern Medical Center at Dallas, Dallas, Texas 75390 9110, USA
    J Urol 180:1228-34. 2008
    ..Preliminary data have suggested phosphodiesterase type 5 inhibitor efficacy in men with lower urinary tract symptoms associated with clinical benign prostatic hyperplasia...
  30. doi request reprint Dutasteride improves outcomes of benign prostatic hyperplasia when evaluated for prostate cancer risk reduction: secondary analysis of the REduction by DUtasteride of prostate Cancer Events (REDUCE) trial
    Claus G Roehrborn
    Department of Urology, University of Texas Southwestern Medical Center, Dallas, Texas 75390 9110, USA
    Urology 78:641-6. 2011
    ....
  31. doi request reprint Clinical outcomes after combined therapy with dutasteride plus tamsulosin or either monotherapy in men with benign prostatic hyperplasia (BPH) by baseline characteristics: 4-year results from the randomized, double-blind Combination of Avodart and Tamsulo
    Claus G Roehrborn
    Department of Urology, University of Texas Southwestern Medical Center, Dallas, TX, USA
    BJU Int 107:946-54. 2011
    ....
  32. doi request reprint Influence of baseline variables on changes in International Prostate Symptom Score after combined therapy with dutasteride plus tamsulosin or either monotherapy in patients with benign prostatic hyperplasia and lower urinary tract symptoms: 4-year results
    Claus G Roehrborn
    Department of Urology, UT Southwestern Medical Center, Dallas, TX, USA
    BJU Int 113:623-35. 2014
    ....
  33. doi request reprint Cost-effectiveness of prostate cancer chemoprevention: a quality of life-years analysis
    Robert S Svatek
    Department of Urology, The University of Texas Southwestern Medical Center, Dallas, TX 75390 9110, USA
    Cancer 112:1058-65. 2008
    ..8% (risk reduction) but questions remain regarding the cost-effectiveness of widespread utilization. The purpose of the current analysis was to evaluate the cost-effectiveness of chemoprevention utilizing a quality-of-life adjustment...
  34. doi request reprint Early postoperative plasma transforming growth factor-beta1 is a strong predictor of biochemical progression after radical prostatectomy
    Shahrokh F Shariat
    Department of Urology, University of Texas Southwestern Medical Center, Dallas, Texas 75390 9110, USA
    J Urol 179:1593-7. 2008
    ....
  35. ncbi request reprint Sustained decrease in incidence of acute urinary retention and surgery with finasteride for 6 years in men with benign prostatic hyperplasia
    Claus G Roehrborn
    The University of Texas Southwestern Medical Center at Dallas, Dallas, Texas 75390 9100, USA
    J Urol 171:1194-8. 2004
    ..We determined the effect of long-term treatment with finasteride on the incidence of acute urinary retention (AUR) and benign prostatic hyperplasia (BPH) related surgery in men with BPH...
  36. ncbi request reprint Tolterodine extended release improves overactive bladder symptoms in men with overactive bladder and nocturia
    Steven A Kaplan
    Department of Urology, Weill Cornell Medical College, New York Presbyterian Hospital, New York, New York 10021, USA
    Urology 68:328-32. 2006
    ..To evaluate the efficacy and safety of nighttime dosing with tolterodine extended release (TER) in men with overactive bladder (OAB) and nocturia...
  37. ncbi request reprint Association of the circulating levels of the urokinase system of plasminogen activation with the presence of prostate cancer and invasion, progression, and metastasis
    Shahrokh F Shariat
    Department of Urology, The University of Texas Southwestern Medical Center, Dallas, TX 75390 9110, USA
    J Clin Oncol 25:349-55. 2007
    ..To assess whether preoperative plasma levels of urokinase-type plasminogen activator (uPA) and its soluble receptor (uPAR) would predict cancer of the prostate (CaP) presence, stage, and prognosis...
  38. doi request reprint Features and outcomes of patients with grade IV renal injury
    Shahrokh F Shariat
    Department of Urology, University of Texas Southwestern Medical Center, Dallas, TX 75390 9110, USA
    BJU Int 102:728-33; discussion 733. 2008
    ....
  39. ncbi request reprint Contemporary laparoscopic and open radical retropubic prostatectomy: pathologic outcomes and Kattan postoperative nomograms are equivalent
    Sangtae Park
    Department of Urology, University of Texas Southwestern Medical Center, Dallas, Texas 75390 9110, USA
    Urology 69:118-22. 2007
    ....
  40. doi request reprint Changes in peak urinary flow and voiding efficiency in men with signs and symptoms of benign prostatic hyperplasia during once daily tadalafil treatment
    Claus G Roehrborn
    University of Texas Southwestern Medical Center, Dallas, TX, USA
    BJU Int 105:502-7. 2010
    ....
  41. doi request reprint Notice of duplicate publication: "Potentially harmful effect of a testosterone dietary supplement on prostate cancer growth and metastasis" (arch intern med. 2008;168[2]:235-236)
    Shahrokh F Shariat
    Department of Urology, The University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, TX 75390 9110
    Arch Intern Med 168:2046-7. 2008
  42. ncbi request reprint The long-term effect of doxazosin, finasteride, and combination therapy on the clinical progression of benign prostatic hyperplasia
    John D McConnell
    University of Texas Southwestern Medical Center, Dallas, TX 75390 9110, USA
    N Engl J Med 349:2387-98. 2003
    ..The long-term effect of these drugs, singly or combined, on the risk of clinical progression is unknown...
  43. ncbi request reprint Survivin expression is associated with features of biologically aggressive prostate carcinoma
    Shahrokh F Shariat
    Department of Urology, University of Texas Southwestern Medical Center, Dallas, Texas 75390 91120, USA
    Cancer 100:751-7. 2004
    ....
  44. doi request reprint BPH progression: concept and key learning from MTOPS, ALTESS, COMBAT, and ALF-ONE
    Claus G Roehrborn
    UT Southwestern Medical Center at Dallas, Dallas, TX 75390 9110, USA
    BJU Int 101:17-21. 2008
    ....
  45. doi request reprint Predictors of costs for robotic-assisted laparoscopic radical prostatectomy
    Christian Bolenz
    Department of Urology, University of Texas Southwestern Medical Center at Dallas, Dallas, TX 75390, USA
    Urol Oncol 29:325-9. 2011
    ..Understanding factors that impact cost may allow reduction in cost of prostate cancer care. We identified factors associated with higher costs in a contemporary series of RALP...
  46. doi request reprint An updated catalog of prostate cancer predictive tools
    Shahrokh F Shariat
    Department of Urology, The University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA
    Cancer 113:3075-99. 2008
    ..Nevertheless, many more predictive tools, comparisons between them, and improvements to existing tools are needed...
  47. ncbi request reprint Anthropometric and metabolic factors and risk of benign prostatic hyperplasia: a prospective cohort study of Air Force veterans
    Amit Gupta
    Department of Urology, University of Texas Southwestern Medical Center, Dallas, Texas 75390 9110, USA
    Urology 68:1198-205. 2006
    ..We investigated the associations of BPH with anthropometric and metabolic parameters in this prospective study of Vietnam War veterans...
  48. ncbi request reprint Efficacy and safety of dutasteride in the four-year treatment of men with benign prostatic hyperplasia
    Claus G Roehrborn
    Department of Urology, University of Texas Southwestern Medical Center at Dallas, Dallas, Texas 75390 9110, USA
    Urology 63:709-15. 2004
    ..To assess the long-term safety and efficacy of dutasteride, a dual type 1 and type 2 5-alpha-reductase inhibitor, in the treatment of symptomatic benign prostatic hyperplasia and associated lower urinary tract symptoms...
  49. ncbi request reprint Implications of the prostate cancer prevention trial: a decision analysis model of survival outcomes
    Yair Lotan
    Department of Urology, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, TX 75390 9110, USA
    J Clin Oncol 23:1911-20. 2005
    ..To assess the estimated effect of finasteride prevention of prostate cancer on overall survival...
  50. ncbi request reprint Expression of survivin and apoptotic biomarkers in benign prostatic hyperplasia
    Shahrokh F Shariat
    Department of Urology, University of Texas Southwestern Medical Center, Dallas, Texas 75390 9110, USA
    J Urol 174:2046-50. 2005
    ..We assessed the differential expression of survivin and other apoptotic markers in stromal and epithelial compartments of benign prostatic hyperplasia (BPH) and normal prostate tissue...
  51. ncbi request reprint Combination therapy with dutasteride and tamsulosin in men with moderate-to-severe benign prostatic hyperplasia and prostate enlargement: the CombAT (Combination of Avodart and Tamsulosin) trial rationale and study design
    Paul Siami
    Department of Urology, Welborn Clinic, Evansville, IN 47714, USA
    Contemp Clin Trials 28:770-9. 2007
    ..5 ng/mL. A total of 4838 subjects have been enrolled. This paper describes the rationale, design and baseline data of the CombAT study...
  52. ncbi request reprint Salvage radiotherapy for recurrent prostate cancer after radical prostatectomy
    Andrew J Stephenson
    Department of Urology, Sidney Kimmel Center for Prostate and Urologic Cancers, Memorial Sloan Kettering Cancer Center, New York, NY, USA
    JAMA 291:1325-32. 2004
    ..Salvage radiotherapy may potentially cure patients with disease recurrence after radical prostatectomy, but previous evidence has suggested that it is ineffective in patients at the highest risk of metastatic disease progression...
  53. pmc A multi-institutional matched-control analysis of adjuvant and salvage postoperative radiation therapy for pT3-4N0 prostate cancer
    Edouard J Trabulsi
    Department of Urology, Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA
    Urology 72:1298-302; discussion 1302-4. 2008
    ..We studied a group of patients undergoing ART by comparing them with a matched control group undergoing SRT after biochemical failure...
  54. pmc Laparoscopic nephrectomy is cost effective compared with open nephrectomy in a large county hospital
    Yair Lotan
    Department of Urology, University of Texas Southwestern Medical Center Dallas, Texas 75390, USA
    JSLS 7:111-5. 2003
    ..To evaluate the experience with laparoscopic nephrectomy in a large county hospital and perform a cost comparison between uncomplicated open and laparoscopic nephrectomy...
  55. ncbi request reprint The effect of dutasteride on the peripheral and transition zones of the prostate and the value of the transition zone index in predicting treatment response
    Leonard S Marks
    Department of Urology, University of California, Los Angeles School of Medicine and Urological Sciences Research Foundation, Los Angeles, California 90232, USA
    J Urol 177:1408-13. 2007
    ..We determined the effects of dutasteride on transition and peripheral zone volume, and the clinical value of the transition zone index in men with benign prostatic hyperplasia...
  56. doi request reprint Cost comparison of robotic, laparoscopic, and open radical prostatectomy for prostate cancer
    Christian Bolenz
    Department of Urology, University of Texas Southwestern Medical Center at Dallas, TX 75390 9110, USA
    Eur Urol 57:453-8. 2010
    ..Demand and utilization of minimally invasive approaches to radical prostatectomy have increased in recent years, but comparative studies on cost are lacking...
  57. doi request reprint Benign prostatic hyperplasia evaluation and management by urologists and primary care physicians: practice patterns from the observational BPH registry
    John T Wei
    Department of Urology, University of Michigan and i3 Drug Safety, Ann Arbor, Michigan 48109 2800, USA
    J Urol 186:971-6. 2011
    ..We examined the evaluation of and management for lower urinary tract symptoms/benign prostatic hyperplasia by physician specialty (urologist vs primary care physician)...
  58. doi request reprint Effects of tadalafil once daily on maximum urinary flow rate in men with lower urinary tract symptoms suggestive of benign prostatic hyperplasia
    Claus G Roehrborn
    Department of Urology, University of Texas Southwestern Medical Center, Dallas, Texas Electronic address
    J Urol 191:1045-50. 2014
    ....
  59. ncbi request reprint Effects of finasteride on serum testosterone and body mass index in men with benign prostatic hyperplasia
    Claus G Roehrborn
    University of Texas Southwestern Medical Center, Dallas, Texas 75390 9110, USA
    Urology 62:894-9. 2003
    ..To examine the effect of finasteride on serum testosterone in men with benign prostatic hyperplasia (BPH)...
  60. ncbi request reprint Verification and incorporation biases in studies assessing screening tests: prostate-specific antigen as an example
    Amit Gupta
    Department of Urology, University of Texas Southwestern Medical Center, Dallas, Texas 75390 9110, USA
    Urology 64:106-11. 2004
    ..We have reviewed how these biases have influenced such studies...
  61. ncbi request reprint Lymphovascular invasion is a pathological feature of biologically aggressive disease in patients treated with radical prostatectomy
    Shahrokh F Shariat
    Department of Urology, University of Texas Southwestern Medical Center, Dallas, Texas 75390 9110, USA
    J Urol 171:1122-7. 2004
    ..We examined whether invasion of lymphatic and/or vascular vessels (LVI), or perineural spaces (PNI) is associated with prostate cancer features and outcome...
  62. pmc Serum dioxin, testosterone, and subsequent risk of benign prostatic hyperplasia: a prospective cohort study of Air Force veterans
    Amit Gupta
    The University of Texas School of Public Health, Regional Campus at Dallas, Dallas, Texas 75390 9110, USA
    Environ Health Perspect 114:1649-54. 2006
    ..It has been hypothesized that dioxins may be partially responsible for an increase of male reproductive tract disorders such as testicular cancer, cryptorchidism, and hypospadias...
  63. doi request reprint Quantifying the contribution of symptom improvement to satisfaction of men with moderate to severe benign prostatic hyperplasia: 4-year data from the CombAT trial
    Claus G Roehrborn
    Department of Urology, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd, J8 148, Dallas, Texas 75390 9110, USA
    J Urol 187:1732-8. 2012
    ..We quantified the magnitude of symptom improvement required to achieve different levels of patient reported satisfaction, as assessed by the Patient Perception of Study Medication questionnaire...
  64. doi request reprint Surgeon fatigue: impact of case order on perioperative parameters and patient outcomes
    Aditya Bagrodia
    Department of Urology, University of Texas Southwestern Medical Center, Dallas, Texas 75390 9110, USA
    J Urol 188:1291-6. 2012
    ..We tested the hypothesis that surgeon fatigue results in worse outcomes for laparoscopic and robot-assisted laparoscopic prostatectomy, and percutaneous nephrolithotomy by comparing outcomes of sequentially scheduled procedures...
  65. doi request reprint Herbal/hormonal dietary supplement possibly associated with prostate cancer progression
    Shahrokh F Shariat
    Department of Urology, University of Texas Southwestern Medical Center, Dallas, TX 75390 9110, USA
    Clin Cancer Res 14:607-11. 2008
    ..After two men developed an unusual course of clinically aggressive prostate cancer within months of starting daily consumption of the same HHDS product, we investigated the effect of this product on prostate cancer progression...
  66. ncbi request reprint Blood biomarkers for prostate cancer detection and prognosis
    Shahrokh F Shariat
    University of Texas Southwestern Medical Center, Department of Urology, 5323 Harry Hines Boulevard, Dallas, TX 75390 9110, USA
    Future Oncol 3:449-61. 2007
    ..With recent advances in biotechnology such as high-throughput molecular analyses, many potential blood biomarkers have been identified and are currently under investigation...
  67. ncbi request reprint Alpha(2) macroglobulin, a PSA binding protein, is expressed in human prostate stroma
    Victor K Lin
    Department of Urology, The University of Texas, Southwestern Medical Center, Dallas, Texas, USA
    Prostate 63:299-308. 2005
    ..It also plays roles in molecular trapping and targeting. In this study, we characterized alpha(2)-M expression in the human prostate...
  68. ncbi request reprint The value of your time: evaluation of effects of changes in medicare reimbursement rates on the practice of urology
    Yair Lotan
    Department of Urology, The University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA
    J Urol 172:1958-62. 2004
    ..We studied the effect of these changes on hourly reimbursement rates for various services provided by urologists...
  69. ncbi request reprint Does finasteride alter the pathology of the prostate and cancer grading?
    David G Bostwick
    Bostwick Laboratories, Richmond, VA 23294, USA
    Clin Prostate Cancer 2:228-35. 2004
    ..Chemoprevention trials with agents such as finasteride that alter morphology should not rely on cancer grading as a secondary endpoint owing to grading bias...
  70. ncbi request reprint Idiopathic scrotal elephantiasis
    Brad J Hornberger
    Department of Urology, University of Texas Southwestern Medical Center, Dallas, Texas 75390 9110, USA
    Urology 65:389. 2005
    ..We present a unique case of a 22-year-old man with idiopathic lymphedema isolated to the scrotum. After acquired causes of lymphedema were ruled out, the patient was treated with scrotectomy and scrotal reconstruction...
  71. ncbi request reprint Alfuzosin 10 mg once daily in the management of acute urinary retention: results of a double-blind placebo-controlled study
    S A McNeill
    Department of Urology, Western General Hospital, Edinburgh, Scotland, United Kingdom
    Urology 65:83-9; discussion 89-90. 2005
    ....
  72. ncbi request reprint The effect of combined androgen ablation on the expression of alpha1A-adrenergic receptor in the human prostate
    Elie A Benaim
    Department of Urology, University of Texas Southwestern Medical Center, Dallas, Texas, USA
    Prostate 60:310-6. 2004
    ..This study was designed to determine whether androgen ablation (AA) affects expression of alpha1A-adrenergic receptors (AR) in the human prostate...
  73. ncbi request reprint The effect of doxazosin, finasteride and combination therapy on nocturia in men with benign prostatic hyperplasia
    Theodore M Johnson
    Birmingham Atlanta Geriatric Research, Education, and Clinical Center, Atlanta Veterans Affairs Medical Center, Decatur, Georgia 30033, USA
    J Urol 178:2045-50; discussion 2050-1. 2007
    ..We evaluated the effectiveness of single or combination drug therapy on nocturia in men with lower urinary tract symptoms suggestive of benign prostatic hyperplasia...
  74. ncbi request reprint Salvage radiotherapy for biochemical failure of radical prostatectomy: a single-institution experience
    Stanley L Liauw
    Department of Radiation Oncology, University of Texas Southwestern Medical Center at Dallas, 75390 9110, USA
    Urology 61:1204-10. 2003
    ....
  75. ncbi request reprint Efficacy and safety of a dual inhibitor of 5-alpha-reductase types 1 and 2 (dutasteride) in men with benign prostatic hyperplasia
    Claus G Roehrborn
    Department of Urology, University of Texas Southwestern Medical Center at Dallas, Dallas, Texas 75390 9110, USA
    Urology 60:434-41. 2002
    ..To study the efficacy and safety of dutasteride, a dual inhibitor of the 5-alpha-reductase isoenzymes types I and II...
  76. ncbi request reprint Storage (irritative) and voiding (obstructive) symptoms as predictors of benign prostatic hyperplasia progression and related outcomes
    Claus G Roehrborn
    Department of Urology, The University of Texas Southwestern Medical Center at Dallas, 75390 9110, USA
    Eur Urol 42:1-6. 2002
    ..To assess the utility of voiding and filling symptom subscores in predicting features of benign prostatic hyperplasia (BPH) progression, including acute urinary retention (AUR) and prostate surgery...
  77. ncbi request reprint Reporting of acute urinary retention in BPH treatment trials: importance of patient follow-up after discontinuation and case definitions
    Claus G Roehrborn
    Department of Urology, The University of Texas Southwestern Medical Center, Dallas, Texas 75390 9110, USA
    Urology 59:811-5. 2002
    ..Because of differences in study designs, the present analysis was undertaken to compare data on the rates of AUR across different BPH trials accurately...
  78. ncbi request reprint Nomograms including nuclear matrix protein 22 for prediction of disease recurrence and progression in patients with Ta, T1 or CIS transitional cell carcinoma of the bladder
    Shahrokh F Shariat
    Department of Urology, The University of Texas Southwestern Medical Center, Dallas, Texas 75390 9110, USA
    J Urol 173:1518-25. 2005
    ..We developed and validated nomograms that accurately predict disease recurrence and progression in patients with Ta, T1, or CIS transitional cell carcinoma (TCC) of the bladder using a large international cohort...
  79. ncbi request reprint Long-term sustained improvement in symptoms of benign prostatic hyperplasia with the dual 5alpha-reductase inhibitor dutasteride: results of 4-year studies
    Claus G Roehrborn
    Department of Urology, University of Texas Southwestern Medical Center, Dallas, TX 75390 9110, USA
    BJU Int 96:572-7. 2005
    ....
  80. pmc Predicting the outcome of salvage radiation therapy for recurrent prostate cancer after radical prostatectomy
    Andrew J Stephenson
    Glickman Urological Institute, Cleveland Clinic Foundation, Cleveland, OH 44195 0001, USA
    J Clin Oncol 25:2035-41. 2007
    ..We developed a nomogram to predict the probability of cancer control at 6 years after SRT for PSA-defined recurrence...
  81. ncbi request reprint Examination of the relationship between symptoms of prostatitis and histological inflammation: baseline data from the REDUCE chemoprevention trial
    J Curtis Nickel
    Department of Urology, Queen s University, Kingston General Hospital, Kingston, Ontario, Canada
    J Urol 178:896-900; discussion 900-1. 2007
    ..5 mg dutasteride daily decreases the risk of biopsy detectable prostate cancer. All men underwent biopsy before study entry, allowing review of the relationship between histological prostate inflammation and prostatitis symptoms...
  82. ncbi request reprint Differences in the rate of lymph node invasion in men with clinically localized prostate cancer might be related to the continent of origin
    Alberto Briganti
    Department of Urology, Vita Salute University San Raffaele, Milan, Italy
    BJU Int 100:528-32. 2007
    ..To test whether the rate of lymph node invasion (LNI) differs between patients treated with radical prostatectomy (RP) at a European or a North American centre...
  83. doi request reprint External validation of a biomarker-based preoperative nomogram predicts biochemical recurrence after radical prostatectomy
    Shahrokh F Shariat
    Cancer Prognostics and Health Outcomes Unit, University of Montreal, Montreal, Quebec, Canada
    J Clin Oncol 26:1526-31. 2008
    ..However, this model was never externally validated. We tested the accuracy of this nomogram in an independent, external cohort...
  84. doi request reprint Comparison of stage migration patterns between Europe and the USA: an analysis of 11 350 men treated with radical prostatectomy for prostate cancer
    Andrea Gallina
    Cancer Prognostics and Health Outcomes Unit, University of Montreal, Montreal, Quebec, Canada
    BJU Int 101:1513-8. 2008
    ..To examine the stage migration patterns in patients treated with radical prostatectomy (RP) for prostate cancer in Europe and in the USA in the last 20 years...
  85. ncbi request reprint Quantifying the impact of prostate volumes, number of biopsy cores and 5alpha-reductase inhibitor therapy on the probability of prostate cancer detection using mathematical modeling
    Robert Serfling
    Department of Mathematical Sciences, University of Texas at Dallas, Richardson, TX 75083, USA
    J Urol 177:2352-6. 2007
    ..By decreasing prostate volume 5alpha-reductase inhibitors may enhance cancer detection, which may explain the greater detection of high grade tumors in the finasteride arm of the Prostate Cancer Prevention Trial...
  86. ncbi request reprint Evidence-based validation of the predictive value of the American Association for the Surgery of Trauma kidney injury scale
    Shahrokh F Shariat
    Department of Urology, University of Texas Southwestern Medical Center at Dallas, Texas 75390 9110, USA
    J Trauma 62:933-9. 2007
    ..To evaluate the predictive value of the American Association for the Surgery of Trauma (AAST) kidney injury scale for the management of traumatic renal injuries...
  87. ncbi request reprint Prostate-specific antigen improves the ability of clinical stage and biopsy Gleason sum to predict the pathologic stage at radical prostatectomy in the new millennium
    Felix K H Chun
    Department of Urology, University Medical Centre, Eppendorf, Hamburg, Germany
    Eur Urol 52:1067-74. 2007
    ..The contemporary ability of prostate-specific antigen (PSA) to predict pathologic stage in men with localized prostate cancer was recently questioned...
  88. ncbi request reprint Effect of 1 mg/day finasteride on concentrations of serum prostate-specific antigen in men with androgenic alopecia: a randomised controlled trial
    Anthony V D'Amico
    Department of Radiation Oncology, Brigham and Women s Hospital and Dana Faber Cancer Institute, Boston, MA 02215, USA
    Lancet Oncol 8:21-5. 2007
    ..We aimed to assess the effect of 1 mg/day finasteride on serum PSA in men aged 40-60 years with male-pattern hair loss...
  89. ncbi request reprint Prediction of pathological stage is inaccurate in men with PSA values above 20 ng/mL
    Andrea Gallina
    Cancer Prognostics and Health Outcomes Unit, University of Montreal, Montreal, Quebec, Canada
    Eur Urol 52:1374-80. 2007
    ..To test this hypothesis, we examined 5193 consecutive patients subjected to radical prostatectomy (RP) for localized prostate cancer (PCa)...
  90. ncbi request reprint Significant upgrading affects a third of men diagnosed with prostate cancer: predictive nomogram and internal validation
    Felix K H Chun
    Department of Urology, University of Hamburg, Hamburg, Germany
    BJU Int 98:329-34. 2006
    ....
  91. ncbi request reprint Baseline factors as predictors of clinical progression of benign prostatic hyperplasia in men treated with placebo
    E David Crawford
    University of Colorado Health Sciences Center, Aurora, Colorado, USA
    J Urol 175:1422-6; discussion 1426-7. 2006
    ..We analyzed data from the placebo arm of the MTOPS trial to determine clinical predictors of BPH progression...
  92. ncbi request reprint Relationship among serum testosterone, sexual function, and response to treatment in men receiving dutasteride for benign prostatic hyperplasia
    Michael Marberger
    Department of Urology, University of Vienna, Wahringer Gurtel 18 20, A 1090 Vienna, Austria
    J Clin Endocrinol Metab 91:1323-8. 2006
    ..Although benign prostatic hyperplasia (BPH) is an androgen-dependent disorder, little is known regarding the influence of serum testosterone levels on sexual or prostate function or clinical response to dutasteride...
  93. ncbi request reprint Development of nomogram to predict acute urinary retention or surgical intervention, with or without dutasteride therapy, in men with benign prostatic hyperplasia
    Kevin M Slawin
    Baylor Prostate Center, Scott Department of Urology, Baylor College of Medicine, Methodist Hospital, Houston, Texas, USA
    Urology 67:84-8. 2006
    ....
  94. ncbi request reprint Combination therapy with doxazosin and finasteride for benign prostatic hyperplasia in patients with lower urinary tract symptoms and a baseline total prostate volume of 25 ml or greater
    Steven A Kaplan
    Columbia University Medical Center, New York, New York, USA
    J Urol 175:217-20; discussion 220-1. 2006
    ..We examined data from the Medical Therapy of Prostatic Symptoms trial to determine the relationship between baseline TPV and the effect of medical therapy in men with LUTS secondary to BPH...
  95. doi request reprint Long-term treatment with finasteride results in a clinically significant reduction in total prostate volume compared to placebo over the full range of baseline prostate sizes in men enrolled in the MTOPS trial
    Steven A Kaplan
    Weill Cornell Medical College, New York, New York 10021, USA
    J Urol 180:1030-2; discussion 1032-3. 2008
    ....