Laure Rittie

Summary

Affiliation: University of Michigan
Country: USA

Publications

  1. pmc Another dimension to the importance of the extracellular matrix in fibrosis
    Laure Rittie
    Department of Dermatology, University of Michigan Medical School, 6447 Medical Building I 1301 E Catherine St, Ann Arbor, MI, USA
    J Cell Commun Signal 9:99-100. 2015
  2. pmc Cellular mechanisms of skin repair in humans and other mammals
    Laure Rittie
    Department of Dermatology, University of Michigan Medical School, 6447 Medical Building I, 1301 E Catherine St, Ann Arbor, MI, 48109, USA
    J Cell Commun Signal 10:103-20. 2016
  3. pmc Eccrine sweat glands are major contributors to reepithelialization of human wounds
    Laure Rittie
    Department of Dermatology, University of Michigan, Ann Arbor, Michigan 48109, USA
    Am J Pathol 182:163-71. 2013
  4. pmc Capturing the finer points of gene expression in psoriasis: beaming in on the CCL19/CCR7 axis
    Laure Rittie
    Department of Dermatology, University of Michigan Medical School, Ann Arbor, Michigan 48109, USA
    J Invest Dermatol 132:1535-8. 2012
  5. pmc Spatial-temporal modulation of CCN proteins during wound healing in human skin in vivo
    Laure Rittie
    Department of Dermatology, University of Michigan, Medical Science Building I, Rm 6447, 1301 E Catherine, Ann Arbor, MI, 48109, USA
    J Cell Commun Signal 5:69-80. 2011
  6. pmc Enzymes used in molecular biology: a useful guide
    Laure Rittie
    Department of Dermatology, University of Michigan, Ann Arbor, MI, USA
    J Cell Commun Signal 2:25-45. 2008
  7. ncbi request reprint Hedgehog signaling maintains hair follicle stem cell phenotype in young and aged human skin
    Laure Rittie
    Department of Dermatology, University of Michigan, Ann Arbor, MI, USA
    Aging Cell 8:738-51. 2009
  8. pmc Amphiregulin carboxy-terminal domain is required for autocrine keratinocyte growth
    Stefan W Stoll
    Department of Dermatology, University of Michigan, Ann Arbor, Michigan 48109, USA
    J Invest Dermatol 130:2031-40. 2010
  9. pmc Metalloproteinase-mediated, context-dependent function of amphiregulin and HB-EGF in human keratinocytes and skin
    Stefan W Stoll
    Department of Dermatology, University of Michigan Medical School, Ann Arbor, MI, USA
    J Invest Dermatol 130:295-304. 2010
  10. pmc Differential ErbB1 signaling in squamous cell versus basal cell carcinoma of the skin
    Laure Rittie
    Department of Dermatology, University of Michigan Medical Center, 1500 East Medical Center Drive, Ann Arbor, MI 48109 0932, USA
    Am J Pathol 170:2089-99. 2007

Detail Information

Publications25

  1. pmc Another dimension to the importance of the extracellular matrix in fibrosis
    Laure Rittie
    Department of Dermatology, University of Michigan Medical School, 6447 Medical Building I 1301 E Catherine St, Ann Arbor, MI, USA
    J Cell Commun Signal 9:99-100. 2015
    ..Targeting this feedback loop might be an efficient therapeutic strategy for IPF. ..
  2. pmc Cellular mechanisms of skin repair in humans and other mammals
    Laure Rittie
    Department of Dermatology, University of Michigan Medical School, 6447 Medical Building I, 1301 E Catherine St, Ann Arbor, MI, 48109, USA
    J Cell Commun Signal 10:103-20. 2016
    ..This review aims at providing the reader with a clear understanding of the similarities and differences that have been reported over the past 100 years between the healing of human wounds and that of other mammals. ..
  3. pmc Eccrine sweat glands are major contributors to reepithelialization of human wounds
    Laure Rittie
    Department of Dermatology, University of Michigan, Ann Arbor, Michigan 48109, USA
    Am J Pathol 182:163-71. 2013
    ..This novel appreciation of the unique importance of eccrine sweat glands for epidermal repair may be exploited to improve our approaches to understanding and treating human wounds...
  4. pmc Capturing the finer points of gene expression in psoriasis: beaming in on the CCL19/CCR7 axis
    Laure Rittie
    Department of Dermatology, University of Michigan Medical School, Ann Arbor, Michigan 48109, USA
    J Invest Dermatol 132:1535-8. 2012
    ..They identify the T-cell activation regulators C-C chemokine ligand 19 and C-C chemokine receptor 7 as potential mediators of immune organization in psoriasis...
  5. pmc Spatial-temporal modulation of CCN proteins during wound healing in human skin in vivo
    Laure Rittie
    Department of Dermatology, University of Michigan, Medical Science Building I, Rm 6447, 1301 E Catherine, Ann Arbor, MI, 48109, USA
    J Cell Commun Signal 5:69-80. 2011
    ....
  6. pmc Enzymes used in molecular biology: a useful guide
    Laure Rittie
    Department of Dermatology, University of Michigan, Ann Arbor, MI, USA
    J Cell Commun Signal 2:25-45. 2008
    ..By pointing out key requirements for each enzymatic activity and clarifying their limitations, we aim at guiding the reader in selecting appropriate enzymatic source and optimal experimental conditions for molecular cloning experiments...
  7. ncbi request reprint Hedgehog signaling maintains hair follicle stem cell phenotype in young and aged human skin
    Laure Rittie
    Department of Dermatology, University of Michigan, Ann Arbor, MI, USA
    Aging Cell 8:738-51. 2009
    ..Together with previously reported knock-out mouse results, these data suggest a role for Hh signaling in maintaining bulge cell phenotype in young and aged human skin...
  8. pmc Amphiregulin carboxy-terminal domain is required for autocrine keratinocyte growth
    Stefan W Stoll
    Department of Dermatology, University of Michigan, Ann Arbor, Michigan 48109, USA
    J Invest Dermatol 130:2031-40. 2010
    ....
  9. pmc Metalloproteinase-mediated, context-dependent function of amphiregulin and HB-EGF in human keratinocytes and skin
    Stefan W Stoll
    Department of Dermatology, University of Michigan Medical School, Ann Arbor, MI, USA
    J Invest Dermatol 130:295-304. 2010
    ..These data show that distinct EGFR ligands stimulate KC behavior in different cellular contexts, and in an MP-dependent fashion...
  10. pmc Differential ErbB1 signaling in squamous cell versus basal cell carcinoma of the skin
    Laure Rittie
    Department of Dermatology, University of Michigan Medical Center, 1500 East Medical Center Drive, Ann Arbor, MI 48109 0932, USA
    Am J Pathol 170:2089-99. 2007
    ..Our results suggest that targeting ErbB1 signaling might be of benefit in the treatment of SCC...
  11. pmc Enhancing structural support of the dermal microenvironment activates fibroblasts, endothelial cells, and keratinocytes in aged human skin in vivo
    Taihao Quan
    Department of Dermatology, University of Michigan, Ann Arbor, Michigan 48109 5609, USA
    J Invest Dermatol 133:658-67. 2013
    ..Thus, fibroblasts in aged human skin retain their capacity for functional activation, which is restored by enhancing structural support of the ECM...
  12. doi request reprint Intraepidermal erbium:YAG laser resurfacing: impact on the dermal matrix
    Jeffrey S Orringer
    Department of Dermatology, University of Michigan Medical School, Ann Arbor, Michigan 48109 0314, USA
    J Am Acad Dermatol 64:119-28. 2011
    ..Various minimally invasive treatments enhance the skin's appearance. Little is known about the molecular mechanisms whereby treatments working at the epidermal level might alter the dermis...
  13. pmc Heparin-binding EGF-like growth factor promotes epithelial-mesenchymal transition in human keratinocytes
    Stefan W Stoll
    Department of Dermatology, University of Michigan Medical Center, Ann Arbor, Michigan 48109 5675, USA
    J Invest Dermatol 132:2148-57. 2012
    ....
  14. doi request reprint Molecular analysis of aggressive microdermabrasion in photoaged skin
    Darius J Karimipour
    Department of Dermatology, University of Michigan, 1500 E Medical Center Dr, 1910 Taubman Center, Ann Arbor, MI 48109, USA
    Arch Dermatol 145:1114-22. 2009
    ..To investigate dermal remodeling effects of crystal-free microdermabrasion on photodamaged skin...
  15. doi request reprint Hypo-collagenesis in photoaged skin predicts response to anti-aging cosmeceuticals
    Dana L Sachs
    Department of Dermatology, University of Michigan, Ann Arbor, Michigan, USA
    J Cosmet Dermatol 12:108-15. 2013
    ..While many cosmeceuticals claim to improve the appearance of photoaged skin, data are lacking regarding their ability to induce molecular responses associated with wrinkle effacement, particularly increased collagen production...
  16. ncbi request reprint Isolation and culture of skin fibroblasts
    Laure Rittie
    Department of Dermatology, University of Michigan, Ann Arbor, MI, USA
    Methods Mol Med 117:83-98. 2005
    ..In this chapter, we describe detailed procedures for establishing and maintaining primary cultures of adult human fibroblasts. We also provide protocols for constructing three-dimensional dermal and skin equivalent culture models...
  17. doi request reprint Induction of collagen by estradiol: difference between sun-protected and photodamaged human skin in vivo
    Laure Rittie
    Department of Dermatology, University of Michigan Medical School, Ann Arbor, MI 48109 0609, USA
    Arch Dermatol 144:1129-40. 2008
    ..To evaluate the effectiveness of topical estradiol in stimulating collagen I and III production in naturally aged and photoaged human skin of postmenopausal women and age-matched men...
  18. pmc Decreased collagen production in chronologically aged skin: roles of age-dependent alteration in fibroblast function and defective mechanical stimulation
    James Varani
    Department of Pathology, The University of Michigan, 1301 Catherine Rd Box 0602, Ann Arbor, MI 48109 USA
    Am J Pathol 168:1861-8. 2006
    ..Based on the findings presented here, we conclude that reduced collagen synthesis in chronologically aged skin reflects at least two different underlying mechanisms: cellular fibroblast aging and a lower level of mechanical stimulation...
  19. pmc Reduced cell cohesiveness of outgrowths from eccrine sweat glands delays wound closure in elderly skin
    Laure Rittie
    Department of Dermatology, University of Michigan Medical School, Ann Arbor, MI, USA
    Aging Cell 15:842-52. 2016
    ..Our findings provide a framework to better understand the mediators of delayed re-epithelialization in aging and further support the importance of ESGs for the repair of human wounds. ..
  20. pmc Transgenic expression of human amphiregulin in mouse skin: inflammatory epidermal hyperplasia and enlarged sebaceous glands
    Yong Li
    Department of Dermatology, University of Michigan Medical School, Ann Arbor, MI, USA
    Exp Dermatol 25:187-93. 2016
    ....
  21. pmc Membrane-Tethered Intracellular Domain of Amphiregulin Promotes Keratinocyte Proliferation
    Stefan W Stoll
    Department of Dermatology, University of Michigan, Ann Arbor, Michigan, USA Electronic address
    J Invest Dermatol 136:444-52. 2016
    ..Our findings uncover an important role of the AREG-CTD in regulating cell division, which may be relevant to tumor resistance to EGFR-directed therapies. ..
  22. ncbi request reprint UV-light-induced signal cascades and skin aging
    Laure Rittie
    Department of Dermatology, University of Michigan, 1150 West Medical Center Drive, R6447 Medical Science I, Ann Arbor, MI 48109 0609, USA
    Ageing Res Rev 1:705-20. 2002
    ....
  23. ncbi request reprint Retinoid-induced epidermal hyperplasia is mediated by epidermal growth factor receptor activation via specific induction of its ligands heparin-binding EGF and amphiregulin in human skin in vivo
    Laure Rittie
    Department of Dermatology, University of Michigan Medical School, University of Michigan, Ann Arbor, Michigan 48109 0609, USA
    J Invest Dermatol 126:732-9. 2006
    ..These data demonstrate the central role of EGFR activation in retinoid-induced epidermal hyperplasia, and suggest that EGFR inhibitors can mitigate retinoid-induced scaling...
  24. pmc Sebaceous Gland Atrophy in Psoriasis: An Explanation for Psoriatic Alopecia?
    Laure Rittie
    Department of Dermatology, University of Michigan, Ann Arbor, Michigan, USA
    J Invest Dermatol 136:1792-800. 2016
    ....
  25. pmc Natural and sun-induced aging of human skin
    Laure Rittie
    Department of Dermatology, University of Michigan Medical School, Ann Arbor, Michigan 48109
    Cold Spring Harb Perspect Med 5:a015370. 2015
    ..Aging also affects wound repair, pigmentation, innervation, immunity, vasculature, and subcutaneous fat homeostasis. Altogether, age-related alterations of skin lead to age-related skin fragility and diseases. ..