Andrew M Poulos
Affiliation: University of California
- Comment on "Cerebellar LTD and learning-dependent timing of conditioned eyelid responses"Kimberly M Christian
Neuroscience Program, University of Southern California, 3641 Watt Way, Los Angeles, CA 90089 2520, USA
Science 304:211; author reply 211. 2004
- Amnesia for early life stress does not preclude the adult development of posttraumatic stress disorder symptoms in ratsAndrew M Poulos
Department of Psychology, Brain Research Institute, Los Angeles, Los Angeles, California UCLA Behavioral Testing Core, Brain Research Institute, Los Angeles, Los Angeles, California Electronic address
Biol Psychiatry 76:306-14. 2014..Here, we used a fear conditioning procedure in juvenile rats before maturation of the neural systems supporting declarative memory to assess the necessity of early memory to the later life development of PTSD-related symptoms...
- Persistence of fear memory across time requires the basolateral amygdala complexAndrew M Poulos
Department of Psychology and Brain Research Institute, University of California, Los Angeles, CA 90095, USA
Proc Natl Acad Sci U S A 106:11737-41. 2009..Collectively, these findings suggest that fear-related plasticity acquired by brain regions outside of the BLA, unlike those acquired in the intact animals, do so for a relatively time-limited period...
- Decremental effects of context exposure following delay eyeblink conditioning in rabbitsAndrew M Poulos
Neuroscience Program, University of Southern California, Los Angeles, CA, USA
Behav Neurosci 120:730-4. 2006..The expression of CRs was substantially reduced following context exposure relative to any retention loss in the home-cage control. Exposure to handling and a novel context facilitated the CRs rather than reducing them...
- Disruption of cerebellar cortical inhibition in the absence of learning promotes sensory-evoked eyeblink responsesAndrew M Poulos
Neurosciences Program, Department of Psychology, University of Southern California, Los Angeles, CA 90095 153, USA
Behav Neurosci 123:694-700. 2009..These results are consistent with dual plasticity models of cerebellar learning and strongly support the general hypothesis that conditioned responses are the result of strengthening of preexisting connections in the nervous system...
- Compensation in the neural circuitry of fear conditioning awakens learning circuits in the bed nuclei of the stria terminalisAndrew M Poulos
Department of Psychology, Brain Research Institute, University of California, Los Angeles, CA 90095 1563, USA
Proc Natl Acad Sci U S A 107:14881-6. 2010..Unlocking such neural compensation holds promise for understanding situations when brain damage impairs normal function or failure to regulate compensatory sites leads to anxiety disorders...
- Timing of conditioned responses utilizing electrical stimulation in the region of the interpositus nucleus as a CSAndrew M Poulos
Neuroscience Program, University of Southern California, Los Angeles, CA 90082 2520, USA
Integr Physiol Behav Sci 39:83-94. 2004..The acquisition of conditioned eyeblink responses by direct electrical stimulation of the IP as a CS thus retains temporal flexibility following shifts in the CS-US delay, as found in standard classical eyeblink conditioning procedures...
- Concussive brain injury enhances fear learning and excitatory processes in the amygdalaMaxine L Reger
UCLA Neurotrauma Laboratory, Department of Neurosurgery, David Geffen School of Medicine, University of California at Los Angeles, CA 90095, USA
Biol Psychiatry 71:335-43. 2012..However, because physically traumatic events typically occur in a highly emotional context, it is unknown whether traumatic brain injury itself is a cause of augmented fear and anxiety...
- The neuroscience of mammalian associative learningMichael S Fanselow
Department of Psychology and Brain Research Institute, University of California Los Angeles, Los Angeles, CA 90095 1563, USA
Annu Rev Psychol 56:207-34. 2005..In this chapter, we describe the orientation that the neuroscience of learning has taken and review some of the progress made within that orientation...
- Brain mechanisms of extinction of the classically conditioned eyeblink responseKarla Robleto
University of Southern California, Neuroscience Program, Los Angeles, California, USA
Learn Mem 11:517-24. 2004..The nature of this phenomenon and identification of the neural substrates necessary for extinction of originally learned responses is the topic of this review...
- Effects of a corneal anesthetic on extinction of the classically conditioned nictitating membrane response in the rabbit (Oryctolagus cuniculus)Karla Robleto
Neuroscience Program, University of Southern California, Los Angeles, California 90089 2520, USA
Behav Neurosci 118:1433-8. 2004..216) relative to the control group (M = 1.32, SEM +/- 0.639) early in extinction. Results seem to suggest that although motor output has been found to play an important role in extinction, corneal sensory feedback is not necessary...
- Retrieval and Reconsolidation Accounts of Fear ExtinctionRavikumar Ponnusamy
Departments of Psychology, Psychiatry and Biobehavioral Sciences, and the Brain Research Institute, University of California Los Angeles, CA, USA
Front Behav Neurosci 10:89. 2016..e., within 6 h). All extinction procedures, except reconsolidation update reduced fear at this short-term test. The findings suggest that strengthened extinction can result from alteration in both retrieval and consolidation processes. ..
- Conditioning- and time-dependent increases in context fear and generalizationAndrew M Poulos
Department of Psychology and Center for Neuroscience, University at Albany, State University of New York, Albany, New York 12222, USA Department of Psychology, University of California, Los Angeles, Los Angeles, California 90095, USA
Learn Mem 23:379-85. 2016..Based on these results, we conclude that the severity or number of foot shocks determines not only the level of fear memory, but also the time-dependent incubation of fear and its generalization across distinct contexts. ..