Craig Porter

Summary

Affiliation: University of Texas Medical Branch
Country: USA

Publications

  1. doi request reprint The metabolic stress response to burn trauma: current understanding and therapies
    Craig Porter
    Department of Surgery, University of Texas Medical Branch, Galveston, TX, USA Shriners Hospitals for Children, Galveston, TX, USA Electronic address
    Lancet 388:1417-1426. 2016
  2. pmc Human and Mouse Brown Adipose Tissue Mitochondria Have Comparable UCP1 Function
    Craig Porter
    Department of Surgery, University of Texas Medical Branch, Galveston, TX 77555, USA Shriners Hospitals for Children, Galveston, Galveston, TX 77550, USA Electronic address
    Cell Metab 24:246-55. 2016
  3. pmc Differential acute and chronic effects of burn trauma on murine skeletal muscle bioenergetics
    Craig Porter
    Metabolism Unit, Shriners Hospitals for Children, Galveston, TX, USA Department of Surgery, University of Texas Medical Branch, Galveston, TX, USA Electronic address
    Burns 42:112-22. 2016
  4. pmc Mitochondrial respiratory capacity and coupling control decline with age in human skeletal muscle
    Craig Porter
    Department of Surgery, University of Texas Medical Branch, Galveston, Texas Shriners Hospitals for Children, Galveston, Texas
    Am J Physiol Endocrinol Metab 309:E224-32. 2015
  5. pmc Uncoupled skeletal muscle mitochondria contribute to hypermetabolism in severely burned adults
    Craig Porter
    Metabolism Unit, Shriners Hospitals for Children, Galveston, Texas Department of Surgery, University of Texas Medical Branch, Galveston, Texas
    Am J Physiol Endocrinol Metab 307:E462-7. 2014
  6. pmc The impact of severe burns on skeletal muscle mitochondrial function
    Craig Porter
    Metabolism Unit, Shriners Hospitals for Children, Galveston, TX, United States
    Burns 39:1039-47. 2013
  7. pmc Amino acid infusion fails to stimulate skeletal muscle protein synthesis up to 1 year after injury in children with severe burns
    Craig Porter
    Metabolism Unit, Shriners Hospitals for Children, Galveston, Texas, USA
    J Trauma Acute Care Surg 74:1480-5. 2013
  8. pmc Does adipose tissue thermogenesis play a role in metabolic health?
    Craig Porter
    Metabolism Unit, Shriners Hospitals for Children, Department of Surgery, University of Texas Medical Branch, Galveston, TX 77550, USA
    J Obes 2013:204094. 2013
  9. pmc Brown Adipose Tissue Is Linked to a Distinct Thermoregulatory Response to Mild Cold in People
    Maria Chondronikola
    Metabolism Unit, Shriners Hospitals for Children GalvestonTX, USA Department of Preventive Medicine and Community Health, University of Texas Medical BranchGalveston, TX, USA Division of Rehabilitation Sciences, Department of Nutrition and Metabolism, University of Texas Medical BranchGalveston, TX, USA Department of Nutrition and Dietetics, Harokopio University of AthensGreece
    Front Physiol 7:129. 2016
  10. pmc Long-Term Skeletal Muscle Mitochondrial Dysfunction is Associated with Hypermetabolism in Severely Burned Children
    Craig Porter
    From the Metabolism Unit, Shriners Hospitals for Children, Galveston, Texas Department of Surgery, University of Texas Medical Branch, Galveston University of Arkansas for Medical Science, Arkansas Children s Nutrition Center, and Arkansas Children s Hospital Research Institute, Little Rock Department of Rehabilitation Sciences, Department of Nutrition and Metabolism, Institute of Translational Sciences, and Department of Internal Medicine, University of Texas Medical Branch, Galveston
    J Burn Care Res 37:53-63. 2016

Collaborators

  • Celeste C Finnerty
  • Csaba Szabo
  • Labros Sidossis
  • Demidmaa Tuvdendorj
  • Jong O Lee
  • Ronald P Mlcak
  • Nicola Abate
  • Maria Chondronikola
  • David N Herndon
  • Tony Chao
  • Elisabet Børsheim
  • Oscar E Suman
  • Elena Volpi
  • Eva C Diaz
  • Sébastien M Labbé
  • Christina Yfanti
  • Palam Annamalai
  • Nicholas M Hurren
  • Fernardo Cesani
  • Blake B Rasmussen
  • John O Ogunbileje
  • Christopher S Fry
  • Paul T Reidy
  • Manish Kumar Saraf
  • Guillermo Foncerrada
  • Tracy Toliver-Kinsky
  • Bartosz Szczesny
  • Manish K Saraf
  • Justin P Hardee
  • Rabia Asghar
  • Gabriel Hundeshagen
  • Christopher Nieten
  • Allan R Brasier
  • Doaa R Abdelrahman
  • Kosaku Shinoda
  • Ravi Radhakrishnan
  • Melinda Sheffield-Moore
  • Yingxin Zhao
  • William J Durham
  • Shingo Kajimura
  • Ioannis Malagaris
  • Paul Wurzer
  • Edgar L Dillon
  • Daniel Wong
  • Karel D Capek
  • Xiaojun Zhang
  • Teresa A Zimmers
  • Maria Camacho-Hughes
  • Anastasia Papadimitriou
  • Zhanpin Wu
  • Doaa Reda Abdelrahman
  • Clark Andersen
  • Anastasia Chaidemenou
  • Matthew Cotter
  • Akbar Ahmad
  • Fredrick J Bohanon
  • Gabor Olah
  • Attila Brunyánszki
  • Martin E Lidell
  • Fernando Cesani
  • James A Carson
  • Hal Hawkins
  • Sven Enerback
  • Clark R Andersen

Detail Information

Publications28

  1. doi request reprint The metabolic stress response to burn trauma: current understanding and therapies
    Craig Porter
    Department of Surgery, University of Texas Medical Branch, Galveston, TX, USA Shriners Hospitals for Children, Galveston, TX, USA Electronic address
    Lancet 388:1417-1426. 2016
    ..We highlight recent developments and important knowledge gaps that need to be pursued to develop novel therapeutic strategies to improve outcomes in burn survivors...
  2. pmc Human and Mouse Brown Adipose Tissue Mitochondria Have Comparable UCP1 Function
    Craig Porter
    Department of Surgery, University of Texas Medical Branch, Galveston, TX 77555, USA Shriners Hospitals for Children, Galveston, Galveston, TX 77550, USA Electronic address
    Cell Metab 24:246-55. 2016
    ..Further, our data demonstrate that human and rodent BAT have similar UCP1 function per mitochondrion. These data indicate that human and rodent BAT are qualitatively similar in terms of UCP1 function. ..
  3. pmc Differential acute and chronic effects of burn trauma on murine skeletal muscle bioenergetics
    Craig Porter
    Metabolism Unit, Shriners Hospitals for Children, Galveston, TX, USA Department of Surgery, University of Texas Medical Branch, Galveston, TX, USA Electronic address
    Burns 42:112-22. 2016
    ..These data highlight a differential response in muscle mitochondrial function to burn trauma, where the timing, degree and mode of dysfunction are dependent on whether the muscle is local or distal to the burn wound...
  4. pmc Mitochondrial respiratory capacity and coupling control decline with age in human skeletal muscle
    Craig Porter
    Department of Surgery, University of Texas Medical Branch, Galveston, Texas Shriners Hospitals for Children, Galveston, Texas
    Am J Physiol Endocrinol Metab 309:E224-32. 2015
    ..Lower respiratory capacity and coupling efficiency result in a reduced capacity for ATP production in skeletal muscle of older adults. ..
  5. pmc Uncoupled skeletal muscle mitochondria contribute to hypermetabolism in severely burned adults
    Craig Porter
    Metabolism Unit, Shriners Hospitals for Children, Galveston, Texas Department of Surgery, University of Texas Medical Branch, Galveston, Texas
    Am J Physiol Endocrinol Metab 307:E462-7. 2014
    ..Our findings suggest that skeletal muscle mitochondrial dysfunction contributes to increased metabolic rate in burn victims. ..
  6. pmc The impact of severe burns on skeletal muscle mitochondrial function
    Craig Porter
    Metabolism Unit, Shriners Hospitals for Children, Galveston, TX, United States
    Burns 39:1039-47. 2013
    ....
  7. pmc Amino acid infusion fails to stimulate skeletal muscle protein synthesis up to 1 year after injury in children with severe burns
    Craig Porter
    Metabolism Unit, Shriners Hospitals for Children, Galveston, Texas, USA
    J Trauma Acute Care Surg 74:1480-5. 2013
    ..Subsequently, the purpose of this study was to determine skeletal muscle FSR in response to AA infusion in severely burned pediatric patients at discharge from hospital and at 6 and 12 months after injury...
  8. pmc Does adipose tissue thermogenesis play a role in metabolic health?
    Craig Porter
    Metabolism Unit, Shriners Hospitals for Children, Department of Surgery, University of Texas Medical Branch, Galveston, TX 77550, USA
    J Obes 2013:204094. 2013
    ....
  9. pmc Brown Adipose Tissue Is Linked to a Distinct Thermoregulatory Response to Mild Cold in People
    Maria Chondronikola
    Metabolism Unit, Shriners Hospitals for Children GalvestonTX, USA Department of Preventive Medicine and Community Health, University of Texas Medical BranchGalveston, TX, USA Division of Rehabilitation Sciences, Department of Nutrition and Metabolism, University of Texas Medical BranchGalveston, TX, USA Department of Nutrition and Dietetics, Harokopio University of AthensGreece
    Front Physiol 7:129. 2016
    ..These results demonstrate a physiologically significant role for BAT in thermoregulation in people. This trial has been registered with Clinaltrials.gov: NCT01791114 (https://clinicaltrials.gov/ct2/show/NCT01791114). ..
  10. pmc Long-Term Skeletal Muscle Mitochondrial Dysfunction is Associated with Hypermetabolism in Severely Burned Children
    Craig Porter
    From the Metabolism Unit, Shriners Hospitals for Children, Galveston, Texas Department of Surgery, University of Texas Medical Branch, Galveston University of Arkansas for Medical Science, Arkansas Children s Nutrition Center, and Arkansas Children s Hospital Research Institute, Little Rock Department of Rehabilitation Sciences, Department of Nutrition and Metabolism, Institute of Translational Sciences, and Department of Internal Medicine, University of Texas Medical Branch, Galveston
    J Burn Care Res 37:53-63. 2016
    ..These quantitative and qualitative derangements in skeletal muscle bioenergetics likely contribute to the long-term pathophysiological stress response to burn trauma. ..
  11. pmc Severe Burn Injury Induces Thermogenically Functional Mitochondria in Murine White Adipose Tissue
    Craig Porter
    Metabolism Unit, Shriners Hospitals for Children and Departments of Surgery, Anesthesiology, and Internal Medicine, University of Texas Medical Branch, Galveston, Texas
    Shock 44:258-64. 2015
    ..These data identify a specific pathology that induces the browning of white adipose tissue in vivo and may offer a mechanistic explanation for the chronic hypermetabolism observed in burn victims. ..
  12. pmc Hypermetabolism and hypercatabolism of skeletal muscle accompany mitochondrial stress following severe burn trauma
    John O Ogunbileje
    Metabolism Unit, Shriners Hospitals for Children, Galveston, Texas Department of Surgery, University of Texas Medical Branch, Galveston, Texas
    Am J Physiol Endocrinol Metab 311:E436-48. 2016
    ..Our results suggest a novel role for the mitochondria in burn-induced cachexia. ..
  13. pmc Browning of Subcutaneous White Adipose Tissue in Humans after Severe Adrenergic Stress
    Labros S Sidossis
    Metabolism Unit, Shriners Hospitals for Children Galveston, 815 Market Street, Galveston, TX 77550, USA Department of Nutrition and Dietetics, Harokopio University, El Venizelou 70, Kallithea 176 76, Greece Department of Internal Medicine, University of Texas Medical Branch, 301 University Boulevard, Galveston, TX 77550, USA Institute of Translational Sciences, University of Texas Medical Branch, 301 University Boulevard, Galveston, TX 77550, USA Department of Surgery, University of Texas Medical Branch, 301 University Boulevard, Galveston, TX 77550, USA Electronic address
    Cell Metab 22:219-27. 2015
    ..Our data demonstrate that human sWAT can transform from an energy-storing to an energy-dissipating tissue, which opens new research avenues in our quest to prevent and treat obesity and its metabolic complications. ..
  14. pmc Brown Adipose Tissue Activation Is Linked to Distinct Systemic Effects on Lipid Metabolism in Humans
    Maria Chondronikola
    Metabolism Unit, Shriners Hospitals for Children, Galveston, TX 77555, USA Department of Preventive Medicine and Community Health, University of Texas Medical Branch, Galveston, TX 77555, USA Department of Nutrition and Metabolism, Division of Rehabilitation Sciences, University of Texas Medical Branch, Galveston, TX 77555, USA Department of Nutrition and Dietetics, Harokopio University of Athens, Athens 176 71, Greece
    Cell Metab 23:1200-6. 2016
    ..The accelerated mobilization and oxidation of lipids upon BAT activation supports a putative role for BAT in the regulation of lipid metabolism in humans. ..
  15. pmc Brown adipose tissue improves whole-body glucose homeostasis and insulin sensitivity in humans
    Maria Chondronikola
    Metabolism Unit, Shriners Hospital for Children, Galveston, TX Department of Preventive Medicine and Community Health, University of Texas Medical Branch, Galveston, TX Department of Nutrition and Metabolism, Division of Rehabilitation Sciences, University of Texas Medical Branch, Galveston, TX Department of Nutrition and Dietetics, Harokopio University of Athens, Athens, Greece
    Diabetes 63:4089-99. 2014
    ....
  16. pmc Predictors of muscle protein synthesis after severe pediatric burns
    Eva C Diaz
    From the Metabolism Unit E C D, D N H, C P, M C, O E S, L S S, E B, Shriners Hospitals for Children Galveston and Departments of Surgery E C D, D N H, C P, M C, O E S, E B, and Internal Medicine L S S, University of Texas Medical Branch, Galveston, Texas Arkansas Children s Nutrition Center E C D, M C, E B Arkansas Children s Hospital Research Institute E C D, M C, E B and Department of Pediatrics E C D, M C, E B, University of Arkansas for Medical Sciences, Little Rock, Arkansas and Sungkyunkwan University J L, Seoul, South Korea
    J Trauma Acute Care Surg 78:816-22. 2015
    ..The objectives of this study were to characterize muscle protein synthesis rate of burned children over a period of 24 months after injury and to identify predictors that influence this response...
  17. pmc Satellite cell activation and apoptosis in skeletal muscle from severely burned children
    Christopher S Fry
    Department of Nutrition and Metabolism, University of Texas Medical Branch, Galveston, TX, USA
    J Physiol 594:5223-36. 2016
    ..The activation and apoptosis of satellite cells probably impacts the recovery of lean tissue following a severe burn, contributing to prolonged frailty in burn survivors...
  18. pmc Morphological Changes in Subcutaneous White Adipose Tissue After Severe Burn Injury
    Manish Kumar Saraf
    From the Shriners Hospitals for Children, Galveston, Texas and University of Texas Medical Branch, Galveston, Texas
    J Burn Care Res 37:e96-103. 2016
    ..A better understanding of morphological and functional changes in sWAT will help discern the mechanisms underlying hypermetabolism in burned patients. ..
  19. pmc Effects of pharmacological interventions on muscle protein synthesis and breakdown in recovery from burns
    Eva C Diaz
    Metabolism Unit, Shriners Hospitals for Children, 815, Market Street, Galveston, TX 77550, USA Department of Surgery, University of Texas Medical Branch, 301 University Blvd, Galveston, TX 77555, USA Arkansas Children s Nutrition Center, Arkansas Children s Hospital Research Institute, and Dept of Pediatrics, University of Arkansas for Medical Sciences, 15 Children s Way, Little Rock, AR 72202, USA Electronic address
    Burns 41:649-57. 2015
    ..The aim of this review is to discuss the literature pertaining to pharmacological interventions aimed at attenuating skeletal muscle catabolism in severely burned patients...
  20. pmc Early rehabilitative exercise training in the recovery from pediatric burn
    Justin P Hardee
    1Department of Exercise Science, University of South Carolina, Columbia, SC 2Metabolism Unit, Shriners Hospitals for Children, Galveston, TX 3Department of Surgery, University of Texas Medical Branch, Galveston, TX 4Department of Internal Medicine, University of Texas Medical Branch, Galveston, TX and 5Shriners Hospitals for Children, Galveston, TX
    Med Sci Sports Exerc 46:1710-6. 2014
    ..The purpose of this study was to determine the effects of early outpatient exercise on muscle mass, function, and fractional synthetic rate in severely burned children...
  21. pmc Skeletal Muscle Protein Breakdown Remains Elevated in Pediatric Burn Survivors up to One-Year Post-Injury
    Tony Chao
    Metabolism Unit, Shriners Hospitals for Children Division of Rehabilitation Sciences, Department of Preventive Medicine and Community Health Department of Surgery, University of Texas Medical Branch, Galveston, Texas Department of Nutrition and Dietetics, Harokopio University of Athens, Athens, Greece Department of Internal Medicine, University of Texas Medical Branch, Galveston, Texas
    Shock 44:397-401. 2015
    ..Muscle FBR exceeds FSR during this time, producing a persistent negative net protein balance, even in the post-prandial state, which likely contributes to the prolonged cachexia seen in burned victims...
  22. pmc Time-Dependent and Organ-Specific Changes in Mitochondrial Function, Mitochondrial DNA Integrity, Oxidative Stress and Mononuclear Cell Infiltration in a Mouse Model of Burn Injury
    Bartosz Szczesny
    Department of Anesthesiology, The University of Texas Medical Branch, Galveston, TX, United States of America
    PLoS ONE 10:e0143730. 2015
    ..Mitochondria may be potential therapeutic targets in the future experimental therapy of burns. ..
  23. pmc Resistance Exercise Training Alters Mitochondrial Function in Human Skeletal Muscle
    Craig Porter
    1Metabolism Unit, Shriners Hospitals for Children, Galveston, TX 2Department of Surgery, University of Texas Medical Branch, Galveston, TX 3Rehabilitation Sciences, University of Texas Medical Branch, Galveston, TX 4Department of Internal Medicine, University of Texas Medical Branch, Galveston, TX and 5Department of Nutrition and Metabolism, University of Texas Medical Branch, Galveston, TX
    Med Sci Sports Exerc 47:1922-31. 2015
    ..Comparatively little is known regarding the effect of resistance exercise training (RET) on skeletal muscle mitochondrial respiratory function...
  24. ncbi request reprint Functional Exercise Capacity in Children With Electrical Burns
    Guillermo Foncerrada
    From the Department of Surgery, University of Texas Medical Branch Galveston Shriners Hospitals for Children, Galveston, Texas Division of Plastic, Aesthetic and Reconstructive Surgery, Department of Surgery, Medical University of Graz, Austria
    J Burn Care Res . 2016
    ..0014). Electrical burns are associated with myoglobinemia and decreased cardiopulmonary fitness...
  25. doi request reprint Palmitoyl-carnitine production by blood cells associates with the concentration of circulating acyl-carnitines in healthy overweight women
    Maria Chondronikola
    Department of Surgery, University of Texas Medical Branch, Galveston, TX 77555, USA Metabolism Unit, Shriners Hospitals for Children, Galveston, TX 77555, USA
    Clin Nutr . 2016
    ..The purpose of this study was to determine if, in humans, blood cells contribute in production of circulating acyl-CNTs and associate with whole-body fat metabolism...
  26. pmc The role of exercise in the rehabilitation of patients with severe burns
    Craig Porter
    1Shriners Hospitals for Children 2Department of Surgery, University of Texas Medical Branch, Galveston, TX and 3Department of Exercise Science, University of South Carolina, Columbia, SC
    Exerc Sport Sci Rev 43:34-40. 2015
    ..Here, we review the evidence for the utility of rehabilitative exercise training in restoring physiological function in burn survivors. ..
  27. pmc Whole body and skeletal muscle protein turnover in recovery from burns
    Craig Porter
    Metabolism Unit, Shriners Hospitals for Children Galveston Galveston, Texas Department of Surgery, University of Texas Medical Branch Galveston, Texas
    Int J Burns Trauma 3:9-17. 2013
    ....
  28. pmc Is the heat surrounding adipose tissue mitochondria warranted?
    Craig Porter
    aMetabolism Unit, Shriners Hospitals for Children bDepartment of Surgery, University of Texas Medical Branch cDepartment of Internal Medicine, University of Texas Medical Branch, Galveston, Texas, USA
    Curr Opin Clin Nutr Metab Care 17:503-8. 2014
    ..The recent discovery of uncoupling protein 1 (UCP1) positive mitochondria in human adipose tissue has rekindled interest in the role of UCP1 in energy balance and metabolic health...