Brandon L Pierce

Summary

Affiliation: University of Chicago
Country: USA

Publications

  1. pmc C-reactive protein, interleukin-6, and prostate cancer risk in men aged 65 years and older
    Brandon L Pierce
    Institute for Public Health Genetics, University of Washington, Seattle, WA, USA
    Cancer Causes Control 20:1193-203. 2009
  2. pmc Genome-wide "pleiotropy scan" identifies HNF1A region as a novel pancreatic cancer susceptibility locus
    Brandon L Pierce
    Department of Health Studies and Comprehensive Cancer Center, University of Chicago, Chicago, Illinois 60637, USA
    Cancer Res 71:4352-8. 2011
  3. pmc Genetic susceptibility to type 2 diabetes is associated with reduced prostate cancer risk
    Brandon L Pierce
    Department of Health Studies, The University of Chicago, Chicago, IL 60637, USA
    Hum Hered 69:193-201. 2010
  4. doi Association study of type 2 diabetes genetic susceptibility variants and risk of pancreatic cancer: an analysis of PanScan-I data
    Brandon L Pierce
    Department of Health Studies and Comprehensive Cancer Center, The University of Chicago, IL, 60637, USA
    Cancer Causes Control 22:877-83. 2011
  5. pmc The impact of patents on the development of genome-based clinical diagnostics: an analysis of case studies
    Brandon L Pierce
    Institute for Public Health Genetics, University of Washington, Seattle, WA, USA
    Genet Med 11:202-9. 2009
  6. pmc Arsenic exposure, dietary patterns, and skin lesion risk in bangladesh: a prospective study
    Brandon L Pierce
    Department of Health Studies, University of Chicago, Illinois, USA
    Am J Epidemiol 173:345-54. 2011
  7. pmc A prospective study of arsenic exposure from drinking water and incidence of skin lesions in Bangladesh
    Maria Argos
    Department of Health Studies, The University of Chicago, Illinois 60637, USA
    Am J Epidemiol 174:185-94. 2011
  8. pmc A prospective study of the synergistic effects of arsenic exposure and smoking, sun exposure, fertilizer use, and pesticide use on risk of premalignant skin lesions in Bangladeshi men
    Stephanie Melkonian
    Department of Health Studies, University of Chicago, Illinois, USA
    Am J Epidemiol 173:183-91. 2011
  9. pmc Genome-wide association study of parity in Bangladeshi women
    Briseis Aschebrook-Kilfoy
    Department of Health Studies, The University of Chicago, Chicago, Illinois, United States of America
    PLoS ONE 10:e0118488. 2015
  10. pmc Arsenic and lung disease mortality in Bangladeshi adults
    Maria Argos
    From the aDepartment of Health Studies, The University of Chicago, Chicago, IL bDepartment of Environmental Health Sciences, Mailman School of Public Health, Columbia University, New York, NY cU Chicago Research Bangladesh URB, Ltd, Dhaka, Bangladesh dPublic Health Sciences Division, International Centre for Diarrhoeal Disease Research, Bangladesh, Dhaka, Bangladesh eDepartment of Environmental Medicine, New York University School of Medicine, New York, NY fDepartments of Medicine and Family Medicine, The University of Chicago, Chicago, IL gDepartment of Medicine, University of North Carolina School of Medicine, Chapel Hill, NC and hDepartments of Medicine and Human Genetics and Comprehensive Cancer Center, The University of Chicago, Chicago, IL
    Epidemiology 25:536-43. 2014

Detail Information

Publications33

  1. pmc C-reactive protein, interleukin-6, and prostate cancer risk in men aged 65 years and older
    Brandon L Pierce
    Institute for Public Health Genetics, University of Washington, Seattle, WA, USA
    Cancer Causes Control 20:1193-203. 2009
    ..21). Our results suggest that circulating CRP and IL-6 do not influence PCa risk. SNPs at the CRP locus are not associated with PCa risk in this cohort, while the association between rs1800795 and PCa risk warrants further investigation...
  2. pmc Genome-wide "pleiotropy scan" identifies HNF1A region as a novel pancreatic cancer susceptibility locus
    Brandon L Pierce
    Department of Health Studies and Comprehensive Cancer Center, University of Chicago, Chicago, Illinois 60637, USA
    Cancer Res 71:4352-8. 2011
    ..This novel "pleiotropy scan" method may be useful for identifying susceptibility loci for other cancer phenotypes...
  3. pmc Genetic susceptibility to type 2 diabetes is associated with reduced prostate cancer risk
    Brandon L Pierce
    Department of Health Studies, The University of Chicago, Chicago, IL 60637, USA
    Hum Hered 69:193-201. 2010
    ..To examine the collective effects of type 1 (T1D) and type 2 diabetes (T2D) risk alleles on prostate cancer (PCa) risk...
  4. doi Association study of type 2 diabetes genetic susceptibility variants and risk of pancreatic cancer: an analysis of PanScan-I data
    Brandon L Pierce
    Department of Health Studies and Comprehensive Cancer Center, The University of Chicago, IL, 60637, USA
    Cancer Causes Control 22:877-83. 2011
    ..To examine associations between recently identified common type 2 diabetes (T2D) susceptibility genetic variants and pancreatic cancer risk...
  5. pmc The impact of patents on the development of genome-based clinical diagnostics: an analysis of case studies
    Brandon L Pierce
    Institute for Public Health Genetics, University of Washington, Seattle, WA, USA
    Genet Med 11:202-9. 2009
    ....
  6. pmc Arsenic exposure, dietary patterns, and skin lesion risk in bangladesh: a prospective study
    Brandon L Pierce
    Department of Health Studies, University of Chicago, Illinois, USA
    Am J Epidemiol 173:345-54. 2011
    ..Eating a diet rich in gourds and root vegetables and increasing dietary diversity may reduce arsenical skin lesion risk in Bangladesh...
  7. pmc A prospective study of arsenic exposure from drinking water and incidence of skin lesions in Bangladesh
    Maria Argos
    Department of Health Studies, The University of Chicago, Illinois 60637, USA
    Am J Epidemiol 174:185-94. 2011
    ..Chronic arsenic exposure from drinking water was associated with increased incidence of skin lesions, even at low levels of arsenic exposure (<100 μg/L)...
  8. pmc A prospective study of the synergistic effects of arsenic exposure and smoking, sun exposure, fertilizer use, and pesticide use on risk of premalignant skin lesions in Bangladeshi men
    Stephanie Melkonian
    Department of Health Studies, University of Chicago, Illinois, USA
    Am J Epidemiol 173:183-91. 2011
    ..Understanding differential arsenic susceptibility allows researchers to develop interventions to prevent the health consequences of this massive problem in the Bangladeshi population and beyond...
  9. pmc Genome-wide association study of parity in Bangladeshi women
    Briseis Aschebrook-Kilfoy
    Department of Health Studies, The University of Chicago, Chicago, Illinois, United States of America
    PLoS ONE 10:e0118488. 2015
    ..However, our results suggest that future studies may want to consider the role of 3 notable SNPs in their analysis...
  10. pmc Arsenic and lung disease mortality in Bangladeshi adults
    Maria Argos
    From the aDepartment of Health Studies, The University of Chicago, Chicago, IL bDepartment of Environmental Health Sciences, Mailman School of Public Health, Columbia University, New York, NY cU Chicago Research Bangladesh URB, Ltd, Dhaka, Bangladesh dPublic Health Sciences Division, International Centre for Diarrhoeal Disease Research, Bangladesh, Dhaka, Bangladesh eDepartment of Environmental Medicine, New York University School of Medicine, New York, NY fDepartments of Medicine and Family Medicine, The University of Chicago, Chicago, IL gDepartment of Medicine, University of North Carolina School of Medicine, Chapel Hill, NC and hDepartments of Medicine and Human Genetics and Comprehensive Cancer Center, The University of Chicago, Chicago, IL
    Epidemiology 25:536-43. 2014
    ..We prospectively investigated the associations of arsenic exposure and arsenical skin lesion status with lung disease mortality in Bangladeshi adults...
  11. pmc Genome-wide association study of smoking behaviours among Bangladeshi adults
    Maria Argos
    Department of Health Studies, The University of Chicago, Chicago, Illinois, USA
    J Med Genet 51:327-33. 2014
    ..We performed a genome-wide association study (GWAS) of tobacco smoking behaviour among a population-based sample of 5354 (2035 ever smokers and 3319 never smokers) men and women in Bangladesh...
  12. pmc Dietary B vitamin intakes and urinary total arsenic concentration in the Health Effects of Arsenic Longitudinal Study (HEALS) cohort, Bangladesh
    Maria Argos
    Department of Health Studies, The University of Chicago, 5841 S Maryland Avenue, MC2007, Chicago, IL 60637, USA
    Eur J Nutr 49:473-81. 2010
    ..Dietary factors influencing the metabolism of ingested arsenic may potentially be important modifiers of the health effects of arsenic in this population...
  13. pmc The Genetic Architecture of Arsenic Metabolism Efficiency:A SNP-Based Heritability Study of Bangladeshi Adults
    Jianjun Gao
    Department of Public Health Sciences, The University of Chicago, Chicago, Illinois, USA
    Environ Health Perspect 123:985-92. 2015
    ..Consumption of arsenic-contaminated drinking water adversely affects health. There is interindividual variation in arsenic metabolism efficiency, partially due to genetic variation in the arsenic methyltransferase (AS3MT) gene region...
  14. pmc Arsenic exposure, telomere length, and expression of telomere-related genes among Bangladeshi individuals
    Jianjun Gao
    Department of Public Health Sciences, The University of Chicago, Chicago, IL 60637, USA
    Environ Res 136:462-9. 2015
    ....
  15. pmc Genome-wide association study identifies chromosome 10q24.32 variants associated with arsenic metabolism and toxicity phenotypes in Bangladesh
    Brandon L Pierce
    Department of Health Studies, The University of Chicago, Chicago, Illinois, United States of America
    PLoS Genet 8:e1002522. 2012
    ..These results have potential translational implications for the prevention and treatment of arsenic-associated toxicities worldwide...
  16. pmc Mediation analysis demonstrates that trans-eQTLs are often explained by cis-mediation: a genome-wide analysis among 1,800 South Asians
    Brandon L Pierce
    Department of Public Health Sciences, The University of Chicago, Chicago, Illinois, United States of America Comprehensive Cancer Center, The University of Chicago, Chicago, Illinois, United States of America
    PLoS Genet 10:e1004818. 2014
    ..Future studies should focus on understanding the mechanisms underlying widespread cis-mediation and their relevance to disease biology, as well as using mediation analysis to improve eQTL discovery. ..
  17. pmc Gene-specific differential DNA methylation and chronic arsenic exposure in an epigenome-wide association study of adults in Bangladesh
    Maria Argos
    Department of Public Health Sciences, The University of Chicago, Chicago, Illinois, USA
    Environ Health Perspect 123:64-71. 2015
    ..Inorganic arsenic is one of the most common naturally occurring contaminants found in the environment. Arsenic is associated with a number of health outcomes, with epigenetic modification suggested as a potential mechanism of toxicity...
  18. pmc Determinants and Consequences of Arsenic Metabolism Efficiency among 4,794 Individuals: Demographics, Lifestyle, Genetics, and Toxicity
    Rick J Jansen
    Department of Public Health Sciences, The University of Chicago, Chicago, Illinois
    Cancer Epidemiol Biomarkers Prev 25:381-90. 2016
    ..The abundance of each species in urine relative to their sum (iAs%, MMA%, and DMA%) varies across individuals, reflecting differences in arsenic metabolism capacity...
  19. doi Unidentified genetic variants influence pancreatic cancer risk: an analysis of polygenic susceptibility in the PanScan study
    Brandon L Pierce
    Department of Health Studies, University of Chicago, Chicago, Illinois 60637, USA
    Genet Epidemiol 36:517-24. 2012
    ..Our results suggest that focusing association studies on genic regions and conducting larger GWA studies can reveal additional PanCa susceptibility loci...
  20. ncbi Genomic scan of 12 hereditary prostate cancer families having an occurrence of pancreas cancer
    Brandon L Pierce
    Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109 1024, USA
    Prostate 67:410-5. 2007
    ....
  21. pmc Telomere length measurement by a novel Luminex-based assay: a blinded comparison to Southern blot
    Brandon L Pierce
    Department of Public Health Sciences, University of ChicagoChicago IL 60615, Chicago, USA Department of Human Genetics, University of ChicagoChicago IL 60615, Chicago, USA Comprehensive Cancer Center, University of ChicagoChicago IL 60615, Chicago, USA
    Int J Mol Epidemiol Genet 7:18-23. 2016
    ..The Luminex assay involves no DNA amplification, which may make Luminex an attractive alternative to PCR-based TL measurement. ..
  22. pmc Novel Luminex Assay for Telomere Repeat Mass Does Not Show Well Position Effects Like qPCR
    Muhammad G Kibriya
    Department of Public Health Sciences, Biological Science Division, The University of Chicago, Chicago, Illinois, United States of America
    PLoS ONE 11:e0155548. 2016
    ..4% was explained by sample-to-sample variation. Our novel Luminex assay for TRM had good precision and did not show the well position effects of the sample that were seen in all three of the qPCR assays that were tested. ..
  23. pmc A genome-wide association study of early-onset breast cancer identifies PFKM as a novel breast cancer gene and supports a common genetic spectrum for breast cancer at any age
    Habibul Ahsan
    Authors Affiliations Center for Cancer Epidemiology and Prevention Departments of Health Studies, Medicine, and Human Genetics Comprehensive Cancer Center, University of Chicago, Chicago, Illinois Department of Health Research and Policy, Stanford University School of Medicine Stanford Cancer Institute, Stanford Cancer Prevention Institute of California, Fremont Department of Preventive Medicine, University of Southern California, Los Angeles Stanford Cancer Institute, Palo Alto, California Epidemiology and Genetics Research Program Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina Department of Environmental Health Sciences, Columbia University Mailman School of Public Health, New York, New York Integrated Cancer Genomics Division, Translational Genomics Research Institute, Phoenix Department of Health Science Research, Mayo Clinic Arizona, Scottsdale, Arizona Program in Molecular and Genetic Epidemiology, Harvard School of Public Health, Boston, Massachusetts Division of Cancer Epidemiology, German Cancer Research Center, Heidelberg Clinic of Gynaecology and Obstetrics, Division for Gynaecological Tumor Genetics, Technische Universität München Max Planck Institute of Psychiatry, Munich Department of Obstetrics and Gynaecology, Division of Molecular Gynaeco Oncology, PMV Research Group at the Department of Child and Adolescent Psychiatry and Psychotherapy, Germany
    Cancer Epidemiol Biomarkers Prev 23:658-69. 2014
    ..2 region may contain multiple distinct breast cancer loci; and the PFKM gene region is worthy of further investigation. These findings should enhance our understanding of the etiology of breast cancer...
  24. doi The effect of non-differential measurement error on bias, precision and power in Mendelian randomization studies
    Brandon L Pierce
    Department of Health Studies and Comprehensive Cancer Center, University of Chicago, Chicago, IL 60637, USA
    Int J Epidemiol 41:1383-93. 2012
    ..In this work, we explore the effect of exposure and outcome measurement error in MR studies...
  25. doi Diabetes mellitus and prostate cancer risk
    Brandon L Pierce
    Epidemiology Program, Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109 1024, USA
    Prostate 68:1126-32. 2008
    ..The objective of this study was to examine the association between PCa risk and several characteristics of DM (duration, age at diagnosis, treatment) in data from two population-based, case-control studies of PCa...
  26. pmc Correlates of circulating C-reactive protein and serum amyloid A concentrations in breast cancer survivors
    Brandon L Pierce
    Cancer Prevention Program, Fred Hutchinson Cancer Research Center, 1100 Fairview Ave N, M4 B402, Seattle, WA 98109 1024, USA
    Breast Cancer Res Treat 114:155-67. 2009
    ..Inflammatory status may be an important prognostic factor for breast cancer. Correlates of markers of inflammation in breast cancer survivors have not been thoroughly evaluated...
  27. pmc Case-only genome-wide interaction study of disease risk, prognosis and treatment
    Brandon L Pierce
    Department of Health Studies Epidemiology, The University of Chicago, Chicago, IL 60637, USA
    Genet Epidemiol 34:7-15. 2010
    ..In the current era of genome-wide analyses, the COGWI design is an efficient and straightforward method for detecting G x G, G x E and pharmacogenetic interactions related to disease risk, prognosis and treatment response...
  28. pmc Power and instrument strength requirements for Mendelian randomization studies using multiple genetic variants
    Brandon L Pierce
    Department of Health Studies, University of Chicago, Chicago, IL, USA
    Int J Epidemiol 40:740-52. 2011
    ..e. instrumental variables (IVs)] of the exposure. Power and IV strength requirements for MR studies using multiple genetic variants have not been explored...
  29. pmc Imputing Gene Expression in Uncollected Tissues Within and Beyond GTEx
    Jiebiao Wang
    Department of Public Health Sciences, University of Chicago, Chicago, IL 60637, USA
    Am J Hum Genet 98:697-708. 2016
    ..More importantly, we showed that by using GTEx data as a reference, one can impute expression levels in inaccessible tissues in non-GTEx expression studies. ..
  30. doi Why are diabetics at reduced risk for prostate cancer? A review of the epidemiologic evidence
    Brandon L Pierce
    Department of Health Studies and Comprehensive Cancer Center, The University of Chicago, IL 60637, USA
    Urol Oncol 30:735-43. 2012
    ..Epidemiological research has reveals a great deal regarding the relationship between diabetes and prostate cancer risk, but additional research is needed to further clarify the mechanisms underlying this inverse association...
  31. pmc A prospective study of body mass index and mortality in Bangladesh
    Brandon L Pierce
    Department of Health Studies, The University of Chicago, Chicago, IL 60637, USA
    Int J Epidemiol 39:1037-45. 2010
    ..However, this relationship is not well characterized in Bangladesh, where the BMI distribution is shifted towards lower values...
  32. ncbi Measuring dietary acculturation in Japanese Americans with the use of confirmatory factor analysis of food-frequency data
    Brandon L Pierce
    Department of Epidemiology and Institute for Public Health Genetics, School of Public Health and Community Medicine, University of Washington, Seattle, WA 98195, USA
    Am J Clin Nutr 86:496-503. 2007
    ..Epidemiologic evidence suggests that dietary changes associated with acculturation to a Western diet may increase the risk of type 2 diabetes in Japanese Americans...