K L Petersen
Affiliation: University of California
- The heat/capsaicin sensitization model: a methodologic studyJesper Dirks
Laboratory of Pain Physiology, Multidisciplinary Pain Center, Herlev University Hospital, Herlev, Denmark
J Pain 4:122-8. 2003..There was no synergistic or additive effect between heat and capsaicin in inducing cutaneous sensitization. Rekindling seems to be the important factor in maintaining stable and long-lasting cutaneous sensitization...
- Will ion-channel blockers be useful for management of nonneuropathic pain?K L Petersen
Department of Neurology, UCSF Pain Clinical Research Center, 94115, USA
J Pain 1:26-34. 2000..Furthermore, the literature suggests that the systemic lidocaine analgesia is both dose and diagnosis dependent...
- Capsaicin evoked pain and allodynia in post-herpetic neuralgiaK L Petersen
Department of Neurology, UCSF Pain Clinical Research Center, University of California, San Francisco, 94115, USA
Pain 88:125-33. 2000..These observations support the hypothesis that allodynia in some PHN patients is a form of chronic secondary hyperalgesia maintained by input from intact and possibly 'irritable' primary afferent nociceptors to a sensitized CNS...
- Effect of remifentanil on pain and secondary hyperalgesia associated with the heat--capsaicin sensitization model in healthy volunteersK L Petersen
Pain Clinical Research Center, Department of Neurology, University of California San Francisco, San Francisco, California 94115, USA
Anesthesiology 94:15-20. 2001..Responsivity of model-associated measures was tested with remifentanil, a potent and ultrashort acting mu-opioid agonist...
- Relief of post-herpetic neuralgia by surgical removal of painful skinKarin L Petersen
Department of Neurology, UCSF Pain Clinical Research Center, University of California San Francisco, 1701 Divisadero Street, Suite 480, San Francisco, CA 94115, USA
Pain 98:119-26. 2002..The results may explain the anatomical basis of the capsaicin-response test and have implications for our understanding of clinical mechanisms underlying PHN pain...
- A randomized study of the effect of oral lamotrigine and hydromorphone on pain and hyperalgesia following heat/capsaicin sensitizationKarin L Petersen
Pain Clinical Research Center and Department of Neurology, University of California, San Francisco, CA 94115, USA
J Pain 4:400-6. 2003....
- Cannabis in painful HIV-associated sensory neuropathy: a randomized placebo-controlled trialD I Abrams
Community Consortium, Positive Health Program, San Francisco General Hospital, San Francisco, CA 94110, USA
Neurology 68:515-21. 2007..To determine the effect of smoked cannabis on the neuropathic pain of HIV-associated sensory neuropathy and an experimental pain model...
- Natural history of sensory function after herpes zosterKarin L Petersen
UCSF Pain Clinical Research Center, Department of Neurology, University of California, San Francisco, CA 94115, USA
Pain 150:83-92. 2010..Sensory recovery proceeded at the same rate in eventual pain-free and eventual PHN subjects and is not a requirement for pain resolution. Early interventions that reduce neural injury or enhance recovery should be of benefit...
- Pilot clinical trial of gabapentin to decrease postoperative delirium in older patientsJ M Leung
Department of Anesthesia and Perioperative Care, University of California, San Francisco, San Francisco, CA 94143 0648, USA
Neurology 67:1251-3. 2006..Postoperative delirium occurred in 5/12 patients (42%) who received placebo vs 0/9 patients who received gabapentin, p = 0.045. The reduction in delirium appears to be secondary to the opioid-sparing effect of gabapentin...
- Gabapentin suppresses cutaneous hyperalgesia following heat-capsaicin sensitizationJesper Dirks
Laboratory of Pain Physiology, Department of Anesthesiology and Intensive Care Medicine, Herlev University Hospital, Herlev, Denmark
Anesthesiology 97:102-7. 2002..The aim of the present study was to link data from animal models and clinical trials for chronic pain by investigating the effect of gabapentin on acute nociception and experimentally induced cutaneous hyperalgesia in healthy volunteers...
- Recommendations for the management of herpes zosterRobert H Dworkin
Department of Anesthesiology, University of Rochester School of Medicine and Dentistry, Rochester, NY, 14642, USA
Clin Infect Dis 44:S1-26. 2007..Specific recommendations for the use of these medications are provided. In addition, suggestions are made for treatments that, when used in combination with antiviral therapy, may further reduce pain and other complications of HZ...