P J Perry
Affiliation: University of Iowa
- Detection of anabolic steroid administration: ratio of urinary testosterone to epitestosterone vs the ratio of urinary testosterone to luteinizing hormoneP J Perry
Department of Psychiatry, College of Medicine, University of Iowa, Iowa City 52246, USA
Clin Chem 43:731-5. 1997..We conclude that the urinary T/LH ratio of > or = 30 is a more sensitive marker of AS use than the urinary T/E ratio of > or = 6 and remains sensitive for twice as long as urinary T/E...
- Therapeutic drug monitoring of antipsychoticsP J Perry
Department of Psychiatry, College of Medicine, Division of Clinical and Administrative Pharmacy, College of Pharmacy, University of Iowa, Iowa City, IA 52246, USA
Psychopharmacol Bull 35:19-29. 2001..Additionally, the utility of therapeutic drug monitoring is enhanced by the availability of prospective dosing schemes for haloperidol, olanzapine, and clozapine...
- Distribution of the serotonin 2C (5HT2C) receptor gene -759C/T polymorphism in patients with schizophrenia and normal controlsVicki L Ellingrod
College of Pharmacy, Clinical and Administrative Division, University of Iowa, Iowa City, USA
Psychiatr Genet 14:93-5. 2004....
- The association of alcohol-induced blackouts and grayouts to blood alcohol concentrationsPaul J Perry
Clinical and Administrative Pharmacy Division, College of Pharmacy, University of Iowa, Iowa City, IA 52242, USA
J Forensic Sci 51:896-9. 2006..This finding clinically concludes that subjects with BAC of 310 g/dL or greater have a 0.50 or greater probability of having an alcoholic blackout...
- Testosterone therapy in late-life major depression in malesPaul J Perry
Division of Clinical Pharmacy, College of Pharmacy, University of Iowa, Iowa City 52242, USA
J Clin Psychiatry 63:1096-101. 2002..The efficacy and safety of testosterone therapy in the treatment of depression in elderly hypogonadal males is inconclusive. The following study identifies a subgroup of elderly depressed males who may benefit from testosterone therapy...
- The association of weight gain and olanzapine plasma concentrationsPaul J Perry
Department of Clinical and Administrative Pharmacy, College of Pharmacy, University of Iowa, Iowa City, IA 52242, USA
J Clin Psychopharmacol 25:250-4. 2005..The association of weight gain with plasma concentrations during treatment with olanzapine may support the utilization of plasma drug concentration as a marker for antipsychotic-induced weight gain in the treatment of schizophrenia...
- Bioavailable testosterone as a correlate of cognition, psychological status, quality of life, and sexual function in aging males: implications for testosterone replacement therapyP J Perry
Clinical and Administrative Pharmacy Division, College of Pharmacy, University of Iowa, Iowa City 52242 1112, USA
Ann Clin Psychiatry 13:75-80. 2001..Overall, bioavailable testosterone was not an important determinant of cognitive, psychological, or sexual functioning or of quality of life. The implications for future studies involving testosterone replacement therapy are discussed...
- Olanzapine plasma concentrations and clinical response: acute phase results of the North American Olanzapine TrialP J Perry
Department of Psychiatry, College of Medicine, University of Iowa, Iowa City, USA
J Clin Psychopharmacol 21:14-20. 2001..2 ng/mL was a predictor of therapeutic response in acutely ill patients with schizophrenia. Males required a higher olanzapine dose to reach this threshold concentration than their female counterparts...
- Olanzapine plasma concentrations and clinical response in acutely ill schizophrenic patientsP J Perry
Department of Psychiatry, College of Medicine, University of Iowa, Iowa City 52242, USA
J Clin Psychopharmacol 17:472-7. 1997....
- Anabolic steroid use in weightlifters and bodybuilders: an internet survey of drug utilizationPaul J Perry
Department of Psychiatry, College of Medicine, and the College of Pharmacy, University of Iowa, Iowa City, IA 52242 1112, USA
Clin J Sport Med 15:326-30. 2005..Prior reports of anabolic steroid use suggest polypharmacy and high doses of injectable agents...
- Olanzapine: an atypical antipsychotic for schizophreniaB C Lund
University of Iowa, College of Pharmacy, 443 S Pharmacy Building, Iowa City, IA 52242 1112, USA
Expert Opin Pharmacother 1:305-23. 2000..While generally considered first-line drugs from an efficacy and adverse effect standpoint, pharmacoeconomic studies are needed to justify the large acquisition cost of olanzapine compared to typical agents...
- Clozapine use in patients with schizophrenia and the risk of diabetes, hyperlipidemia, and hypertension: a claims-based approachB C Lund
Division of Clinical and Administrative Pharmacy, College of Pharmacy, University of Iowa, 443 S Pharmacy Bldg, Iowa City, IA 52242 1112, USA
Arch Gen Psychiatry 58:1172-6. 2001..However, investigators have been unable to clearly demonstrate this association when compared with a control group receiving conventional antipsychotics...
- Ziprasidone, a new atypical antipsychotic drugR M Carnahan
Clinical and Administrative Pharmacy Division, College of Pharmacy, University of Iowa, Iowa City 52242-1112, USA
Pharmacotherapy 21:717-30. 2001..In contrast, ziprasidone has a low propensity for causing weight gain. For patients requiring an antipsychotic drug, ziprasidone represents a new treatment option with a limited adverse effect profile...
- Bupropion SR vs. methylphenidate vs. placebo for attention deficit hyperactivity disorder in adultsS Kuperman
Department of Psychiatry, College of Medicine, University of Iowa, Iowa City 52242, USA
Ann Clin Psychiatry 13:129-34. 2001..14). Neuropsychological testing demonstrated trends favoring drug treatment on measures of immediate recall and verbal fluency. While bupropion SR may be a viable clinical alternative for adults with ADHD, further investigation is needed...
- Fenfluramine treatment of autism: relationship of treatment response to blood levels of fenfluramine and norfenfluramineJ H Beeghly
University of Iowa, Iowa City
J Autism Dev Disord 17:541-8. 1987..The results of the study, while providing minimal support in themselves for the effectiveness of fenfluramine, do raise the possibility that fenfluramine blood levels might be related to treatment response...
- Failed challenge with quetiapine after neuroleptic malignant syndrome with conventional antipsychoticsC D Hatch
Clinical and Administrative Division, College of Pharmacy, University of Iowa, Iowa City 52242-1112, USA
Pharmacotherapy 21:1003-6. 2001..Few cases of quetiapine-induced NMS have been reported. A 54-year-old man was unsuccessfully challenged with quetiapine after conventional antipsychotic-induced NMS...
- Risk of mortality associated with antipsychotic and other neuropsychiatric drugs in pneumonia patientsMitchell J Barnett
The Center for Research in the Implementation of Innovative Strategies in Practice, Iowa City Veterans Administration Hospital, Iowa City, IA 52246, USA
J Clin Psychopharmacol 26:182-7. 2006..To evaluate the use of typical and atypical antipsychotic medications and associated in-hospital mortality in a group of Veterans Administration (VA) patients with pneumonia...
- Comparison of rates of potentially inappropriate medication use according to the Zhan criteria for VA versus private sector medicare HMOsMitchell J Barnett
Health Services Research Specialist, Iowa City VAMC, Highway 1, Iowa City, IA 52246, USA
J Manag Care Pharm 12:362-70. 2006..Inappropriate prescribing in the elderly is common, but rates across different health care systems and the impact of formulary restrictions are not well described...
- Methodological concerns in a trial of ziprasidone and olanzapineRyan M Carnahan
Am J Psychiatry 162:1391; author reply 1391-2. 2005
- Weight gain associated with the -759C/T polymorphism of the 5HT2C receptor and olanzapineVicki L Ellingrod
University of Iowa, College of Pharmacy, Iowa, USA
Am J Med Genet B Neuropsychiatr Genet 134:76-8. 2005..Weight gain from atypical antipsychotic use has become a significant problem. Recent reports have liked the -759 polymorphism of the 5HT2C receptor and obesity as well as weight gain from chlorpromazine, risperidone, and clozapine...
- The concurrent use of anticholinergics and cholinesterase inhibitors: rare event or common practice?Ryan M Carnahan
Clinical and Administrative Pharmacy, College of Pharmacy, University of Iowa, Iowa City, USA
J Am Geriatr Soc 52:2082-7. 2004..To measure the prevalence of anticholinergic use cross-sectionally in patients receiving cholinesterase inhibitors and to describe change in use of anticholinergics upon inception of cholinesterase inhibitor treatment...
- Depression in aging men: the role of testosteroneRyan M Carnahan
Clinical and Administrative Pharmacy, College of Pharmacy, University of Iowa, Iowa City, Iowa 52242, USA
Drugs Aging 21:361-76. 2004..Testosterone has demonstrated usefulness in the treatment of a number of depressed populations, but further studies are needed to fully elucidate its role in the treatment of depressive syndromes in the aging male...
- Anabolic steroids: a review for the clinicianEric C Kutscher
Western Missouri Mental Health Center, Kansas City, Missouri 64108, USA
Sports Med 32:285-96. 2002..This review will address the common anabolic steroid misconceptions held by many of today's athletes by providing an evaluation of the scientific literature related to AS in athletic performance...
- Psychiatric prescribing trends and practices in Iowa's prisonsBrian C Lund
Pharmacoepidemiology, College of Pharmacy, University of Iowa, Iowa City, 52242 1112, USA
Psychiatr Serv 53:1023-4. 2002..The use of antipsychotics remained relatively constant, but expenditures increased ninefold. In contrast, both use of and expenditures for antidepressants increased tremendously, from $215 to $1,929 per 100 inmates...
- Comparison of risk of cerebrovascular events in an elderly VA population with dementia between antipsychotic and nonantipsychotic usersMitchell J Barnett
Center for Research in the Implementation of Innovative Strategies in Practice, Veterans Administration Hospital, Iowa City, IA, USA
J Clin Psychopharmacol 27:595-601. 2007..This study examined the risk of a CVE in patients diagnosed with Alzheimer or vascular dementia while being treated with SGA, first-generation antipsychotics, or no antipsychotic medication...
- 5HT2A and 5HT2C receptor polymorphisms and predicting clinical response to olanzapine in schizophreniaVicki L Ellingrod
J Clin Psychopharmacol 22:622-4. 2002
- Measures of aggression and mood changes in male weightlifters with and without androgenic anabolic steroid usePaul J Perry
Clinical and Administrative Pharmacy Division, College of Pharmacy, University of Iowa, Iowa City, IA 52246, USA
J Forensic Sci 48:646-51. 2003....
- Development of a computer algorithm for defining an active drug list using an automated pharmacy databaseBrian C Lund
Laureate Psychiatric Research Center, Laureate Psychiatric Clinics and Hospital, 6655 South Yale Avenue, Tulsa, OK 74136, USA
J Clin Epidemiol 56:802-6. 2003..Such determinations often require the creation of a drug regimen at a particular point in time. The objective of this study was to develop a computer algorithm for defining a cross-sectional active drug list...
- Aripiprazole, a novel atypical antipsychotic drugTami R Argo
College of Pharmacy, University of Iowa, Iowa City, Iowa 52242 1112, USA
Pharmacotherapy 24:212-28. 2004..Patients receiving aripiprazole experienced EPS at a rate similar to that seen with placebo. Aripiprazole provides a new treatment option with limited adverse effects for patients in need of antipsychotic therapy...
- Risperidone versus clonidine in the treatment of children and adolescents with Tourette's syndromeGary R Gaffney
University of Iowa College of Medicine, Iowa City, USA
J Am Acad Child Adolesc Psychiatry 41:330-6. 2002..To evaluate the efficacy and tolerability of risperidone in comparison with clonidine in the treatment of children and adolescents with Tourette's syndrome (TS)...
- A critical appraisal of the utility of the serum anticholinergic activity assay in research and clinical practiceRyan M Carnahan
University of Iowa, College of Pharmacy, 415 S Pharmacy Building, Iowa City, Iowa 52242 1112, USA
Psychopharmacol Bull 36:24-39. 2002....