Andrew B Peitzman

Summary

Affiliation: University of Pittsburgh
Country: USA

Publications

  1. ncbi request reprint Status of trauma and acute care surgery in the United States
    Andrew B Peitzman
    Department of Surgery, University of Pittsburgh, Pittsburgh 15213, USA
    Ulus Travma Acil Cerrahi Derg 14:1-4. 2008
  2. pmc 2013 WSES guidelines for management of intra-abdominal infections
    Massimo Sartelli
    Department of Surgery, Macerata Hospital, Macerata, Italy
    World J Emerg Surg 8:3. 2013
  3. doi request reprint Nonoperative management of blunt abdominal trauma: have we gone too far?
    Andrew B Peitzman
    Department of Surgery, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania 15213, USA
    Surg Infect (Larchmt) 10:427-33. 2009
  4. ncbi request reprint Damage-control laparotomy
    John C Lee
    Department of Surgery, University of Pittsburgh, UPMC Presbyterian, Pittsburgh, Pennsylvania 15213, USA
    Curr Opin Crit Care 12:346-50. 2006
  5. ncbi request reprint Hypothermia in massive transfusion: have we been paying enough attention to it?
    Benjamin R Reynolds
    Division of General Surgery and Trauma, Department of Surgery, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania 15213, USA
    J Trauma Acute Care Surg 73:486-91. 2012
  6. ncbi request reprint Debunking the survival bias myth: characterization of mortality during the initial 24 hours for patients requiring massive transfusion
    Joshua B Brown
    Division of General Surgery and Trauma, Department of Surgery, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania 15213, USA
    J Trauma Acute Care Surg 73:358-64; discussion 364. 2012
  7. pmc Goal-directed resuscitation in the prehospital setting: a propensity-adjusted analysis
    Joshua B Brown
    Department of Surgery, Division of General Surgery and Trauma, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania 15213, USA
    J Trauma Acute Care Surg 74:1207-12; discussion 1212-4. 2013
  8. pmc American College of Surgeons trauma center verification versus state designation: are Level II centers slipping through the cracks?
    Joshua B Brown
    Division of General Surgery and Trauma, Department of Surgery, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania 15213, USA
    J Trauma Acute Care Surg 75:44-9; discussion 49. 2013
  9. doi request reprint Body adipose content is independently associated with a higher risk of organ failure and nosocomial infection in the nonobese patient postinjury
    Rebecca D Edmonds
    Division of General Surgery and Trauma, Department of Surgery, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania 15213, USA
    J Trauma 70:292-8. 2011
  10. doi request reprint Is there a role for aggressive use of fresh frozen plasma in massive transfusion of civilian trauma patients?
    Frederick A Moore
    Department of Surgery, The Methodist Hospital, Houston, TX, USA
    Am J Surg 196:948-58; discussion 958-60. 2008

Collaborators

Detail Information

Publications84

  1. ncbi request reprint Status of trauma and acute care surgery in the United States
    Andrew B Peitzman
    Department of Surgery, University of Pittsburgh, Pittsburgh 15213, USA
    Ulus Travma Acil Cerrahi Derg 14:1-4. 2008
    ..The Institute of Medicine has recommended the development of regional centers of surgical specialists, analogous to trauma systems. The training of surgeons in ACS will address the manpower issue to some degree...
  2. pmc 2013 WSES guidelines for management of intra-abdominal infections
    Massimo Sartelli
    Department of Surgery, Macerata Hospital, Macerata, Italy
    World J Emerg Surg 8:3. 2013
    ..The 2013 update of the World Society of Emergency Surgery (WSES) guidelines for the management of intra-abdominal infections contains evidence-based recommendations for management of patients with intra-abdominal infections...
  3. doi request reprint Nonoperative management of blunt abdominal trauma: have we gone too far?
    Andrew B Peitzman
    Department of Surgery, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania 15213, USA
    Surg Infect (Larchmt) 10:427-33. 2009
    ..Avoidance of a laparotomy with its short-term and long-term risks is of obvious benefit to the patient...
  4. ncbi request reprint Damage-control laparotomy
    John C Lee
    Department of Surgery, University of Pittsburgh, UPMC Presbyterian, Pittsburgh, Pennsylvania 15213, USA
    Curr Opin Crit Care 12:346-50. 2006
    ..The purpose of this review is to discuss current concepts in damage-control laparotomy in trauma and general surgery patients...
  5. ncbi request reprint Hypothermia in massive transfusion: have we been paying enough attention to it?
    Benjamin R Reynolds
    Division of General Surgery and Trauma, Department of Surgery, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania 15213, USA
    J Trauma Acute Care Surg 73:486-91. 2012
    ..We sought to characterize the importance of temperature as a risk factor for poor outcome relative to the changes in MT resuscitation that have occurred...
  6. ncbi request reprint Debunking the survival bias myth: characterization of mortality during the initial 24 hours for patients requiring massive transfusion
    Joshua B Brown
    Division of General Surgery and Trauma, Department of Surgery, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania 15213, USA
    J Trauma Acute Care Surg 73:358-64; discussion 364. 2012
    ..We sought to characterize mortality during the first 24 hours while controlling for time varying effects of transfusion to minimize survival bias...
  7. pmc Goal-directed resuscitation in the prehospital setting: a propensity-adjusted analysis
    Joshua B Brown
    Department of Surgery, Division of General Surgery and Trauma, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania 15213, USA
    J Trauma Acute Care Surg 74:1207-12; discussion 1212-4. 2013
    ..Optimal PH crystalloid resuscitation strategies remain unclear in blunt trauma as does the influence of PH hypotension. The objective was to characterize outcomes for PH crystalloid volume in patients with and without PH hypotension...
  8. pmc American College of Surgeons trauma center verification versus state designation: are Level II centers slipping through the cracks?
    Joshua B Brown
    Division of General Surgery and Trauma, Department of Surgery, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania 15213, USA
    J Trauma Acute Care Surg 75:44-9; discussion 49. 2013
    ..Single-center experience has shown that American College of Surgeons (ACS) trauma verification can improve outcomes. The current objective was to compare mortality between ACS-verified and state-designated centers in a national sample...
  9. doi request reprint Body adipose content is independently associated with a higher risk of organ failure and nosocomial infection in the nonobese patient postinjury
    Rebecca D Edmonds
    Division of General Surgery and Trauma, Department of Surgery, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania 15213, USA
    J Trauma 70:292-8. 2011
    ..We sought to avoid the confounding effects attributable to obesity and determine the association of BMI and outcomes following injury in nonobese patients...
  10. doi request reprint Is there a role for aggressive use of fresh frozen plasma in massive transfusion of civilian trauma patients?
    Frederick A Moore
    Department of Surgery, The Methodist Hospital, Houston, TX, USA
    Am J Surg 196:948-58; discussion 958-60. 2008
    ..Damage control resuscitation (DCR) with early plasma in combat casualties requiring massive transfusion (MT) decreases early deaths from bleeding...
  11. pmc Characterization of acute coagulopathy and sexual dimorphism after injury: females and coagulopathy just do not mix
    Joshua B Brown
    Division of General Surgery and Trauma, Department of Surgery, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA
    J Trauma Acute Care Surg 73:1395-400. 2012
    ..It remains unclear whether presence of ATC alters sex-based outcomes after injury. This study's objective was to characterize the sex dimorphism after severe injury in the presence and absence of ATC...
  12. doi request reprint Early lower extremity fracture fixation and the risk of early pulmonary embolus: filter before fixation?
    Raquel M Forsythe
    Division of General Surgery and Trauma, Department of Surgery, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania 15213, USA
    J Trauma 70:1381-8. 2011
    ..Those patients at highest risk in this early vulnerable window postinjury are not well characterized. We sought to determine those patients at highest risk for an early pulmonary embolism (PE) after injury...
  13. pmc Preinjury statin use is associated with a higher risk of multiple organ failure after injury: a propensity score adjusted analysis
    Matthew D Neal
    Division of General Surgery and Trauma, Department of Surgery, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania 15213, USA
    J Trauma 67:476-82; discussion 482-4. 2009
    ..We sought to determine whether preinjury statin (PIS) use was associated with improved outcome in severely injured blunt trauma patients...
  14. doi request reprint An FFP:PRBC transfusion ratio >/=1:1.5 is associated with a lower risk of mortality after massive transfusion
    Jason L Sperry
    Division of General Surgery and Trauma, Departments of Surgery, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA
    J Trauma 65:986-93. 2008
    ....
  15. doi request reprint Anterior thoracic surgical approaches in the treatment of spinal infections and neoplasms
    Matthew J Schuchert
    Division of Thoracic and Foregut Surgery, Department of Cardiothoracic Surgery, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania Electronic address
    Ann Thorac Surg 97:1750-6; discussion 1756-7. 2014
    ..In this study, we review the perioperative outcomes in patients undergoing anterior spinal exposure for infection and neoplasm...
  16. pmc Crystalloid to packed red blood cell transfusion ratio in the massively transfused patient: when a little goes a long way
    Matthew D Neal
    Division of General Surgery and Trauma, Department of Surgery, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania 15213, USA
    J Trauma Acute Care Surg 72:892-8. 2012
    ..We hypothesized that an increased crystalloid:PRBC (C:PRBC) ratio would be associated with increased morbidity and poor outcome after MT...
  17. doi request reprint Hepatic resection in the management of complex injury to the liver
    Patricio Polanco
    University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania 15213, USA
    J Trauma 65:1264-9; discussion 1269-70. 2008
    ..Delayed, planned anatomic resection was also applied...
  18. doi request reprint Fresh frozen plasma is independently associated with a higher risk of multiple organ failure and acute respiratory distress syndrome
    Gregory A Watson
    Division of General Surgery and Trauma, Department of Surgery, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania 15213, USA
    J Trauma 67:221-7; discussion 228-30. 2009
    ..We hypothesized that plasma-rich transfusion components would be independently associated with a lower risk of mortality but result in a greater risk of morbid complications...
  19. doi request reprint Delay to therapeutic interventional radiology postinjury: time is of the essence
    Gina M Howell
    Division of General Surgery and Trauma, Department of Surgery, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA
    J Trauma 68:1296-300. 2010
    ..The importance of time to control of hemorrhage for therapeutic IR procedures has not been adequately characterized...
  20. doi request reprint Over reliance on computed tomography imaging in patients with severe abdominal injury: is the delay worth the risk?
    Matthew D Neal
    Department of Surgery, Division of General Surgery and Trauma, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania 15213, USA
    J Trauma 70:278-84. 2011
    ..We sought to analyze whether the use of abdominal CT (ABD CT) in patients with abdominal injury requiring laparotomy results in a significant delay and a higher risk of poor outcome...
  21. doi request reprint The association between air ambulance distribution and trauma mortality
    Zachary J Rhinehart
    Department of Surgery, University of Pittsburgh, Pittsburgh, PA 15213, USA
    Ann Surg 257:1147-53. 2013
    ..To determine whether increasing distance between helicopter ambulance airbase and either home residence or referring facility is associated with an increased risk of injury-related mortality...
  22. pmc Defining geriatric trauma: when does age make a difference?
    Nicholas W Goodmanson
    Division of General Surgery and Trauma, Department of Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA
    Surgery 152:668-74; discussion 674-5. 2012
    ....
  23. ncbi request reprint Evaluation of a 15-year experience with splenic injuries in a state trauma system
    Brian G Harbrecht
    Department of Surgery, University of Pittsburgh, Pittsburgh, PA 15213, USA
    Surgery 141:229-38. 2007
    ..We hypothesized that outcomes for patients with splenic injuries have improved as the paradigm for splenic injury treatment has shifted...
  24. pmc Prehospital use of nonsteroidal anti-inflammatory drugs (NSAIDs) is associated with a reduced incidence of trauma-induced coagulopathy
    Matthew D Neal
    Division of General Surgery and Trauma, Department of Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA Department of Surgery, Denver Health Medical Center and the University of Colorado Health Sciences Center, Denver Division of General Surgery and Trauma, Harborview Medical Center and the Department of Surgery, University of Washington, Seattle Division of Burn, Trauma, Critical Care, Department of Surgery, University of Texas Southwestern Medical Center, Dallas and Department of Surgery, University of California, San Francisco
    Ann Surg 260:378-82. 2014
    ..To determine whether prehospital nonsteroidal anti-inflammatory drug (NSAID) use may lead to a reduced incidence of trauma-induced coagulopathy (TIC) in severely injured patients...
  25. doi request reprint Use of a massive transfusion protocol in nontrauma patients: activate away
    Lauren M McDaniel
    Department of Surgery, University of Pittsburgh, Pittsburgh, PA 15213, USA
    J Am Coll Surg 216:1103-9. 2013
    ..The current study was designed to investigate whether an MTP could be used effectively in GMS patients without detrimentally impacting resource allocation...
  26. pmc Radiographic assessment of splenic injury without contrast: is contrast truly needed?
    Douglas R Murken
    Division of General Surgery and Trauma, Department of Surgery, Presbyterian Hospital, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA
    Surgery 152:676-82; discussion 682-4. 2012
    ..However, a substantial proportion of injured patients have contraindications to i.v. contrast. Little information exists concerning the repercussions of CT imaging without i.v. contrast, specifically for splenic injury...
  27. pmc Racial disparities and sex-based outcomes differences after severe injury
    Jason L Sperry
    Division of General Surgery andTrauma, Department of Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA
    J Am Coll Surg 214:973-80. 2012
    ..The prevalence of these variants is known to differ across race. We sought to characterize racial differences and the strength of any sex-based dimorphism post-injury...
  28. doi request reprint Predictors of acute posttraumatic stress disorder symptoms following civilian trauma: highest incidence and severity of symptoms after assault
    Louis H Alarcon
    Department of Surgery, University of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA
    J Trauma Acute Care Surg 72:629-35; discussion 635-7. 2012
    ..The incidence and risk factors for PTSD are not well described in the civilian trauma population. We proposed to screen all trauma patients in the outpatient trauma clinic for acute PTSD symptoms and identify risk factors for PTSD...
  29. pmc Incidental radiographic findings after injury: dedicated attention results in improved capture, documentation, and management
    Jason L Sperry
    Division of General Surgery and Trauma, Department of Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA
    Surgery 148:618-24. 2010
    ..We hypothesized a dedicated incidental finding coordinator would increase incidental finding capture and promote notification, follow-up, and documentation of incidental finding events...
  30. ncbi request reprint Angiography for blunt splenic trauma does not improve the success rate of nonoperative management
    Brian G Harbrecht
    Department of Surgery, University of Louisville, Louisville, KY 40292, USA
    J Trauma 63:44-9. 2007
    ..Previous reports, however, have compared SAE with historical controls. We compared nonoperative success with SAE with a contemporaneous group treated nonoperatively without SAE...
  31. pmc Development and Validation of the Air Medical Prehospital Triage Score for Helicopter Transport of Trauma Patients
    Joshua B Brown
    Division of General Surgery and Trauma, Department of Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA Division of Acute Care Surgery, Department of Surgery, University of Rochester Medical Center, Rochester, NY Department of Emergency Medicine, University of Pittsburgh Medical Center, Pittsburgh, PA
    Ann Surg 264:378-85. 2016
    ..The aim of this study was to develop and internally validate a triage score that can identify trauma patients at the scene who would potentially benefit from helicopter emergency medical services (HEMS)...
  32. pmc External validation of the Air Medical Prehospital Triage Score for identifying trauma patients likely to benefit from scene helicopter transport
    Joshua B Brown
    1 Division of General Surgery and Trauma, Department of Surgery, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania 15213 2 Division of Acute Care Surgery, Department of Surgery, University of Rochester Medical Center, Rochester, New York 14642 3 Department of Emergency Medicine, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania 15213
    J Trauma Acute Care Surg . 2016
    ..The study objective was to validate the effectiveness of the AMPT score to identify patients with a survival benefit from HEMS using the Pennsylvania Trauma Outcomes Study (PTOS) registry...
  33. pmc Helicopter transport improves survival following injury in the absence of a time-saving advantage
    Joshua B Brown
    Division of General Surgery and Trauma, Department of Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA
    Surgery 159:947-59. 2016
    ..The objective was to examine the association of survival with HEMS compared with GEMS transport across similar prehospital transport times...
  34. pmc X chromosome-linked IRAK-1 polymorphism is a strong predictor of multiple organ failure and mortality postinjury
    Jason L Sperry
    From the Division of Trauma and General Surgery, Department of Surgery, University of Pittsburgh, PA
    Ann Surg 260:698-703; discussion 703-5. 2014
    ..IRAK-1 is key intermediate in the toll-like receptor (TLR) pathway thought to drive inflammation postinjury...
  35. pmc Pretrauma center red blood cell transfusion is associated with reduced mortality and coagulopathy in severely injured patients with blunt trauma
    Joshua B Brown
    Division of General Surgery and Trauma, Department of Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA Department of Surgery, University of California, San Francisco, CA Division of Burn, Trauma, Critical Care, Department of Surgery, University of Texas Southwestern Medical Center, Dallas, TX Division of General Surgery and Trauma, Harborview Medical Center, and the Department of Surgery, University of Washington, Seattle, WA and Department of Surgery, Denver Health Medical Center, and the University of Colorado Health Sciences Center, Denver, CO
    Ann Surg 261:997-1005. 2015
    ..To evaluate the association of pretrauma center (PTC) red blood cell (RBC) transfusion with outcomes in severely injured patients...
  36. pmc Multidisciplinary acute care research organization (MACRO): if you build it, they will come
    Barbara J Early
    Department of Critical Care Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA
    J Trauma Acute Care Surg 75:106-9. 2013
    ..We sought to characterize the effects of implementation of a multidisciplinary acute care research organization (MACRO) at a busy tertiary referral university setting...
  37. pmc Changes in massive transfusion over time: an early shift in the right direction?
    Benjamin C Kautza
    Division of General Surgery and Trauma, Department of Surgery, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania 15213, USA
    J Trauma Acute Care Surg 72:106-11. 2012
    ..We sought to characterize changes in resuscitation which have occurred over time in a cohort severely injured patients requiring MT...
  38. ncbi request reprint Is outcome after blunt splenic injury in adults better in high-volume trauma centers?
    Brian G Harbrecht
    Department of Surgery, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania 15213, USA
    Am Surg 71:942-8; discussion 948-9. 2005
    ..These data suggest that ACS criteria for trauma centers level designation are not associated with differences in outcome in the treatment of adult blunt splenic injuries in this regional trauma system...
  39. doi request reprint Male gender is associated with excessive IL-6 expression following severe injury
    Jason L Sperry
    Division of Trauma and General Surgery, Department of Surgery, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA
    J Trauma 64:572-8; discussion 578-9. 2008
    ....
  40. ncbi request reprint Impact of Volume Change Over Time on Trauma Mortality in the United States
    Joshua B Brown
    Division of Trauma and General Surgery, Department of Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA Department of Critical Care Medicine, University of Pittsburgh Medical Center, Pittsburgh, PA
    Ann Surg . 2016
    ..To evaluate the association of trauma center volume change over time with mortality...
  41. pmc Not all prehospital time is equal: Influence of scene time on mortality
    Joshua B Brown
    From the Division of Trauma and General Surgery J B B, M R R, R M F, B R R, A B P, T R B, J L S, Department of Surgery, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania and Division of Acute Care Surgery M L G, W M H, Department of Surgery, University of Rochester Medical Center, Rochester, New York
    J Trauma Acute Care Surg 81:93-100. 2016
    ..It is unclear whether specific PH time patterns affect outcomes. Our objective was to evaluate the association of PH time interval distribution with mortality...
  42. doi request reprint Radiographic assessment of ground-level falls in elderly patients: Is the "PAN-SCAN" overdoing it?
    Christopher R Dwyer
    Departments of Surgery, Mercy and Presbyterian Hospitals, University of Pittsburgh Medical Center, Pittsburgh, PA
    Surgery 154:816-20; discussion 820-2. 2013
    ..We sought to characterize the changes in practice over time and the utility of PAN-SCAN imaging in elderly patients who fall and require admission to a trauma center...
  43. doi request reprint The swinging pendulum: a national perspective of nonoperative management in severe blunt liver injury
    Patricio M Polanco
    From the Division of General Surgery and Trauma, Department of Surgery, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania
    J Trauma Acute Care Surg 75:590-5. 2013
    ..Our objective was to examine current trends of NOM for severe blunt liver injury from a national perspective...
  44. doi request reprint Assessment of platelet transfusion for reversal of aspirin after traumatic brain injury
    Arshad M Bachelani
    Division of General Surgery and Trauma, Department of Surgery, Mercy and Presbyterian Hospital, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA
    Surgery 150:836-43. 2011
    ..Assessment of platelet inhibition and reversal by platelet transfusion after TBI has not been adequately characterized...
  45. pmc Effect of the modified Glasgow Coma Scale score criteria for mild traumatic brain injury on mortality prediction: comparing classic and modified Glasgow Coma Scale score model scores of 13
    Jorge Humberto Mena
    Department of Surgery, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
    J Trauma 71:1185-92; discussion 1193. 2011
    ..We investigated the effect of this modification on mortality prediction, comparing patients with a GCS score of 13 classified as moderate TBI (classic model) to patients with GCS score of 13 classified as mild TBI (modified model)...
  46. ncbi request reprint Increased interactive format for Morbidity & Mortality conference improves educational value and enhances confidence
    Jose M Prince
    Department of Surgery, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
    J Surg Educ 64:266-72. 2007
    ..We analyzed which features of M&M case reviews are associated with greater perceived educational value and enhanced confidence to deal with similar future clinical scenarios...
  47. doi request reprint Massive transfusion in trauma patients: tissue hemoglobin oxygen saturation predicts poor outcome
    Frederick A Moore
    Department of Surgery, The Methodist Hospital, Houston Texas, USA
    J Trauma 64:1010-23. 2008
    ....
  48. ncbi request reprint Surgical rescue: The next pillar of acute care surgery
    Matthew E Kutcher
    Division of Trauma and General Surgery, Department of Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA Section of General Surgery, Trauma, and Surgical Critical Care, Yale School of Medicine, New Haven, CT
    J Trauma Acute Care Surg . 2016
    ..However, the critical role of ACS in the rescue of patients with a surgical complication has not been explored. We here describe the role of 'surgical rescue' in the practice of Acute Care Surgery (ACS)...
  49. pmc Elevated Admission Base Deficit Is Associated with a Complex Dynamic Network of Systemic Inflammation Which Drives Clinical Trajectories in Blunt Trauma Patients
    Othman Abdul-Malak
    Department of Surgery, University of Pittsburgh, Pittsburgh, PA 15213, USA
    Mediators Inflamm 2016:7950374. 2016
    ..These results suggest that elevated admission BD is associated with differential immune/inflammatory pathways, which subsequently could predispose patients to follow a complicated clinical course...
  50. pmc Geographic Variation in Outcome Benefits of Helicopter Transport for Trauma in the United States: A Retrospective Cohort Study
    Joshua B Brown
    Division of General Surgery and Trauma, Department of Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA Division of Acute Care Surgery, Department of Surgery, University of Rochester Medical Center, Rochester, NY
    Ann Surg 263:406-12. 2016
    ..Evaluate the effect of US geographic region on outcomes of helicopter transport (HT) for trauma...
  51. pmc Systolic blood pressure criteria in the National Trauma Triage Protocol for geriatric trauma: 110 is the new 90
    Joshua B Brown
    From the Division of General Surgery and Trauma J B B, R M F, T R B, A B P, J L S, Department of Surgery, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania and Division of Acute Care Surgery M L G, N A S, Department of Surgery, University of Rochester Medical Center, Rochester, New York
    J Trauma Acute Care Surg 78:352-9. 2015
    ..The objective was to evaluate the impact of substituting an SBP of less than 110 mm Hg for the current SBP of less than 90 mm Hg criterion within the NTTP on triage performance and mortality...
  52. pmc Trends in survival and early functional outcomes from hospitalized severe adult traumatic brain injuries, pennsylvania, 1998 to 2007
    Alvaro I Sánchez
    Departments of Surgery, University of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA
    J Head Trauma Rehabil 27:159-69. 2012
    ..To determine trends for in-hospital survival and functional outcomes at acute care hospital discharge for patients with severe adult traumatic brain injury (SATBI) in Pennsylvania, during 1998 to 2007...
  53. ncbi request reprint Failure of nonoperative management of abdominal solid organ injuries
    Dan A Galvan
    Department of Critical Care Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA
    Curr Opin Crit Care 12:590-4. 2006
    ..It has proven to be of unequivocal benefit to the majority of hemodynamically stable pediatric and adult patients who have suffered blunt liver or splenic trauma. Offsetting these gains, has been the presence of failures...
  54. ncbi request reprint Nonoperative management of severe blunt splenic injury: are we getting better?
    Gregory A Watson
    Department of Surgery, University of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA
    J Trauma 61:1113-8; discussion 1118-9. 2006
    ..The infrequency of these injuries has made evaluation of factors critical to their management difficult...
  55. ncbi request reprint Defining the contribution of renal dysfunction to outcome after traumatic injury
    Brian G Harbrecht
    Department of Surgery, University of Louisville, Louisville, Kentucky 40292, USA
    Am Surg 73:836-40. 2007
    ..0 mg/dL is associated with a significantly increased likelihood of death in injured patients and is a stronger predictor than other common indicators of renal impairment...
  56. ncbi request reprint Failure of observation of blunt splenic injury in adults: variability in practice and adverse consequences
    Andrew B Peitzman
    Department of Surgery, University of Pittsburgh, Presbyterian University Hospital, Pittsburgh, PA 15213, USA
    J Am Coll Surg 201:179-87. 2005
    ..The purpose of this multiinstitutional study by the Eastern Association for the Surgery of Trauma was to determine common variables in failure of nonoperative management of blunt splenic injury in adults...
  57. doi request reprint Preventability classification in mortality cases: a reliability study
    Michael D Pasquale
    Department of Surgery, Lehigh Valley Hospital, Allentown, Pennsylvania 18105 1556, USA
    J Trauma 67:1097-102. 2009
    ..This study was performed to evaluate inter-rater reliability of POPIMS software for mortality classification...
  58. pmc Characterization of sex dimorphism following severe thermal injury
    Jessica I Summers
    From the Division of General Surgery and Trauma, Department of Surgery, University of Pittsburgh Medical Center, Pennsylvania
    J Burn Care Res 35:484-90. 2014
    ..Further investigation is required to thoroughly characterize the mechanisms responsible for these divergent outcomes. ..
  59. doi request reprint Risk factors for death in elderly patients with facial fractures secondary to falls
    Julio A Clavijo-Alvarez
    Division of Plastic and Reconstructive Surgery, Department of Surgery, University of Pittsburgh, Pittsburgh, Pennsylvania 15261, USA
    J Craniofac Surg 23:494-8. 2012
    ..Our objective was to review the demographics, outcomes, and risk factors associated with death in elderly patients with facial fractures in a single-institution level I trauma center...
  60. ncbi request reprint Admission hypothermia and outcome after major trauma
    Henry E Wang
    Department of Emergency Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA
    Crit Care Med 33:1296-301. 2005
    ..The goal of this study was to evaluate the independent association between admission hypothermia and mortality after major trauma, with adjustment for clinical confounders...
  61. doi request reprint Current management of hepatic trauma
    Greta L Piper
    Department of Surgery, University of Pittsburgh, F 1265, UPMC Presbyterian, Pittsburgh, PA 15213, USA
    Surg Clin North Am 90:775-85. 2010
    ..Anatomic or nonanatomic liver resection is required in 2% to 5% of liver injuries. Mortality with liver injury following resection is 9% with current advances...
  62. pmc Prehospital lactate improves accuracy of prehospital criteria for designating trauma activation level
    Joshua B Brown
    Division of General Surgery and Trauma, Department of Surgery J B B, J L S, T R B, A B P, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania Department of Emergency Medicine E B L, Medical College of Wisconsin, Milwaukee, Wisconsin and Department of Emergency Medicine F X G, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania
    J Trauma Acute Care Surg 81:445-52. 2016
    ..Prehospital lactate has shown promise in predicting trauma center resource requirements. Our objective was to investigate the added value of incorporating prehospital lactate in an algorithm to designate trauma activation level...
  63. pmc Geographic distribution of trauma centers and injury-related mortality in the United States
    Joshua B Brown
    From the Division of General Surgery and Trauma, Department of Surgery, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania
    J Trauma Acute Care Surg 80:42-9; discussion 49-50. 2016
    ..The objective was to evaluate whether geographic distribution of trauma centers correlates with injury mortality across state trauma systems...
  64. doi request reprint The importance of empiric abdominal computed tomography after urgent laparotomy for trauma: do they reveal unexpected injuries?
    Joshua J Weis
    Division of General Surgery and Trauma, Department of Surgery, University of Pittsburgh, Pittsburgh, PA
    Surgery 156:979-85. 2014
    ....
  65. pmc Pre-trauma center red blood cell transfusion is associated with improved early outcomes in air medical trauma patients
    Joshua B Brown
    Division of General Surgery and Trauma, Department of Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA
    J Am Coll Surg 220:797-808. 2015
    ..Pre-trauma center (PTC) RBC transfusion is growing and preliminary evidence suggests improved outcomes. The study objective was to evaluate the association of PTC RBC transfusion with outcomes in air medical trauma patients...
  66. pmc Evidence-based improvement of the National Trauma Triage Protocol: The Glasgow Coma Scale versus Glasgow Coma Scale motor subscale
    Joshua B Brown
    From the Division of General Surgery and Trauma J B B, R M F, A B P, T R B, J L S, Department of Surgery, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania and Division of Acute Care Surgery N A S, M L G, Department of Surgery, University of Rochester Medical Center, Rochester, New York
    J Trauma Acute Care Surg 77:95-102; discussion 101-2. 2014
    ..This study evaluated performance of the NTTP if GCSm is substituted for the current GCS score ≤ 13 criterion...
  67. doi request reprint Evolving role of endovascular techniques for traumatic vascular injury: a changing landscape?
    Laura E Avery
    Department of Surgery, Mercy and Presbyterian Hospitals, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA
    J Trauma Acute Care Surg 72:41-6; discussion 46-7. 2012
    ....
  68. ncbi request reprint Hepatic dysfunction increases length of stay and risk of death after injury
    Brian G Harbrecht
    Department of Surgery, University of Pittsburgh, Pennsylvania, USA
    J Trauma 53:517-23. 2002
    ..The relative importance of dysfunction or failure of different organ systems to recovery from critical illness is unclear. The purpose of this study was to evaluate the contribution of hepatic dysfunction to outcome after injury...
  69. ncbi request reprint Physical medicine and rehabilitation consultation: relationships with acute functional outcome, length of stay, and discharge planning after traumatic brain injury
    Amy K Wagner
    Department of Physical Medicine and Rehabilitation, University of Pittsburgh, School of Medicine, Pennsylvania 15213, USA
    Am J Phys Med Rehabil 82:526-36. 2003
    ..The purpose of this study was to delineate relationships between physical medicine and rehabilitation consultation in this population and acute functional outcome, length of stay, and discharge planning...
  70. ncbi request reprint Cytochrome P-450 activity is differentially altered in severely injured patients
    Brian G Harbrecht
    Department of Surgery, University of Pittsburgh, Pittsburgh, PA, USA
    Crit Care Med 33:541-6. 2005
    ..To assess whether changes in cytochrome P-450 (CYP) activity of specific CYP enzymes occur in severely injured patients and to assess changes in CYP activity during recovery...
  71. pmc The effects of trauma center care, admission volume, and surgical volume on paralysis after traumatic spinal cord injury
    Carlos Aitor Macias
    The CRISMA Laboratory Clinical Research, Investigation, and Systems Modeling of Acute Illness, Department of Critical Care Medicine, University of Pittsburgh, Pittsburgh, PA 15213, USA
    Ann Surg 249:10-7. 2009
    ..We hypothesized a priori that trauma center care, by contrast to nontrauma center care, is associated with reduced paralysis at discharge...
  72. doi request reprint Technical challenges and utility of anterior exposure for thoracic spine pathology
    Brian L Pettiford
    Heart, Lung, and Esophageal Surgery Institute, and Department of General Surgery, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA
    Ann Thorac Surg 86:1762-8. 2008
    ..We reviewed our surgical experience and the perioperative outcomes of these spinal approaches. Relevant technical and anatomic considerations of each procedure are highlighted...
  73. doi request reprint MRI is unnecessary to clear the cervical spine in obtunded/comatose trauma patients: the four-year experience of a level I trauma center
    Nestor D Tomycz
    Departments of Neurological Surgery, University of Pittsburgh Medical Center, PA, USA
    J Trauma 64:1258-63. 2008
    ..However, currently available data are inconclusive as to the necessity of MRI in the C-spine clearance of obtunded or comatose trauma patients with a normal CT...
  74. ncbi request reprint A brief episode of hypotension increases mortality in critically ill trauma patients
    Mazen S Zenati
    Department of Surgery, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
    J Trauma 53:232-6; discussion 236-7. 2002
    ..Hypotension is associated with increased mortality, however previous studies have failed to account for the depth and duration of hypotension. We evaluated the effect of the duration of hypotension on outcome in injured patients...
  75. ncbi request reprint The Department of Surgery at the School of Medicine at the University Of Pittsburgh, Pittsburgh, Pa
    Timothy R Billiar
    Department of Surgery, Presbyterian University Hospital, Pittsburgh, PA 15213, USA
    Arch Surg 139:466-8. 2004
  76. doi request reprint Frequency and follow-up of incidental findings on trauma computed tomography scans: experience at a level one trauma center
    Marc David Munk
    Department of Emergency Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15213, USA
    J Emerg Med 38:346-50. 2010
    ..Our objective was to quantify the frequency of these incidental CT findings in trauma patients. A secondary goal was to determine how often these lesions were communicated to patients and how often patients were referred for follow-up...
  77. ncbi request reprint Out-of-hospital endotracheal intubation and outcome after traumatic brain injury
    Henry E Wang
    Department of Emergency Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA
    Ann Emerg Med 44:439-50. 2004
    ..This study compares the effects of out-of-hospital endotracheal intubation versus emergency department (ED) endotracheal intubation on mortality and neurologic and functional outcome after severe traumatic brain injury...
  78. doi request reprint The role of acute care surgery in the treatment of severe, complicated Clostridium difficile-associated disease
    Evie H Carchman
    Department of Surgery, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
    J Trauma Acute Care Surg 73:789-800. 2012
    ..Novel operative approaches that preserve the colon and minimize operative morbidity may prove to remove the barriers to earlier surgical treatment for fulminant CDAD and improve outcomes...
  79. ncbi request reprint Management of adult blunt splenic injuries: comparison between level I and level II trauma centers
    Brian G Harbrecht
    Department of Surgery, University of Pittsburgh Medical Center, F1264 200 Lothrop Street, Pittsburgh, PA 15213, USA
    J Am Coll Surg 198:232-9. 2004
    ..The factors important in determining outcome when managing adult blunt splenic injuries continue to be debated. Whether trauma center level designation (Level I versus Level II) affects patient management has not been evaluated...
  80. doi request reprint Institutional protocol improves retrievable inferior vena cava filter recovery rate
    Sae Hee Ko
    Department of Surgery, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA
    Surgery 146:809-14; discussion 814-6. 2009
    ..This study reports the impact of an institutional protocol on retrieval rates of RIVCF at a level I trauma center...
  81. ncbi request reprint Characterization of the expression of inducible nitric oxide synthase in rat and human liver during hemorrhagic shock
    Joy L Collins
    Department of Surgery, University of Pittsburgh Cancer Institute, University of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA
    Shock 19:117-22. 2003
    ..Collectively, these results suggest that hepatic iNOS expression, associated with peroxisomal localization, is an early molecular response to HS in experimental animals and possibly in human patients with trauma with HS...
  82. ncbi request reprint The modulation of hepatic injury and heat shock expression by inhibition of inducible nitric oxide synthase after hemorrhagic shock
    John M Menezes
    Department of Surgery, University of Pittsburgh, Pennsylvania 15213, USA
    Shock 17:13-8. 2002
    ..We conclude that excessive NO production from iNOS contributes to shock-induced hepatic injury. Our data suggest HSP expression may reflect the degree of ischemic injury after hemorrhage...
  83. ncbi request reprint TRISS unexpected survivors: an outdated standard?
    Rob Norris
    University of Pittsburgh School of Medicine, PA, USA
    J Trauma 52:229-34. 2002
    ..Our hypothesis was that the level of care that is currently expected has made the TRISS unexpected survivors a statistical phenomenon only...
  84. ncbi request reprint Variability in trauma center outcomes for patients with moderate intracranial injury
    Stanley Z Trooskin
    University of Medicine and Dentistry of New Jersey Robert Wood Johnson Medical School, NJ, USA
    J Trauma 57:998-1005. 2004
    ..The analytic results were supplemented with peer review of MII patients with unexpected outcomes and identified potential process of care variables...