Daniel F Pauly

Summary

Affiliation: University of Florida
Country: USA

Publications

  1. ncbi request reprint Ischemic heart disease: metabolic approaches to management
    Daniel F Pauly
    University of Florida College of Medicine, Division of Cardiovascular Medicine, Gainesville, Florida 32610, USA
    Clin Cardiol 27:439-41. 2004
  2. doi request reprint Renin-angiotensin gene polymorphisms and neurohormonal inhibition
    Daniel F Pauly
    Division of Cardiovascular Medicine, Section of Heart Failure and Transplantation, University of Florida College of Medicine, Box 100277, Gainesville, FL 32610, USA
    Heart Fail Clin 6:25-6. 2010
  3. ncbi request reprint The role of carnitine in myocardial dysfunction
    Daniel F Pauly
    Division of Cardiovascular Medicine, University of Florida, Gainesville, FL 32610, USA
    Am J Kidney Dis 41:S35-43. 2003
  4. doi request reprint The slow cardiac myosin regulatory light chain in heart failure
    Daniel F Pauly
    Clin Cardiol 34:10-1. 2011
  5. ncbi request reprint Cardiac function and heart failure
    Daniel F Pauly
    Division of Cardiovascular Medicine, University of Florida College of Medicine, Gainesville, Florida, USA
    J Am Coll Cardiol 45:24B-29B. 2005
  6. ncbi request reprint Synergistic polymorphisms of beta1 and alpha2C-adrenergic receptors and the influence on left ventricular ejection fraction response to beta-blocker therapy in heart failure
    Maximilian T Lobmeyer
    Department of Pharmacy Practice, University of Florida, Gainesville, FL 32610, USA
    Pharmacogenet Genomics 17:277-82. 2007
  7. ncbi request reprint Beta1-adrenergic receptor polymorphisms and left ventricular remodeling changes in response to beta-blocker therapy
    Steven G Terra
    Department of Pharmacy Practice, University of Florida College of Pharmacy, Gainesville, FL 32610, USA
    Pharmacogenet Genomics 15:227-34. 2005
  8. ncbi request reprint Arterial-wave reflections are increased in heart failure patients with a left-ventricular assist device
    Richard S Schofield
    Department of Veterans Affairs Medical Center, Gainesville, Florida, USA
    Am J Hypertens 20:622-8. 2007
  9. ncbi request reprint Initial heart rate and systolic blood pressure predict outcomes in chronic heart failure patients who are evaluated for cardiac transplant
    Juan M Aranda
    University of Florida College of Medicine, Department of Medicine, Division of Cardiovascular Medicine, Gainesville, Florida, USA
    Clin Cardiol 30:282-7. 2007
  10. pmc Multimarker approach predicts adverse cardiovascular events in women evaluated for suspected ischemia: results from the National Heart, Lung, and Blood Institute-sponsored Women's Ischemia Syndrome Evaluation
    Christopher B Arant
    Division of Cardiovascular Medicine, University of Florida College of Medicine, Gainesville, Florida, USA
    Clin Cardiol 32:244-50. 2009

Detail Information

Publications46

  1. ncbi request reprint Ischemic heart disease: metabolic approaches to management
    Daniel F Pauly
    University of Florida College of Medicine, Division of Cardiovascular Medicine, Gainesville, Florida 32610, USA
    Clin Cardiol 27:439-41. 2004
    ..Metabolic modulators also include the nutriceuticals L-carnitine and D-ribose. The available evidence regarding the benefits of each of these five agents is reviewed...
  2. doi request reprint Renin-angiotensin gene polymorphisms and neurohormonal inhibition
    Daniel F Pauly
    Division of Cardiovascular Medicine, Section of Heart Failure and Transplantation, University of Florida College of Medicine, Box 100277, Gainesville, FL 32610, USA
    Heart Fail Clin 6:25-6. 2010
    ..Such studies will continue to define the role of renin-angiotensin pharmacogenetics in patients with heart failure due to underlying cardiac dysfunction...
  3. ncbi request reprint The role of carnitine in myocardial dysfunction
    Daniel F Pauly
    Division of Cardiovascular Medicine, University of Florida, Gainesville, FL 32610, USA
    Am J Kidney Dis 41:S35-43. 2003
    ..Because a dialysis-related carnitine disorder is common among these patients, L-carnitine supplementation would be among these specific therapies...
  4. doi request reprint The slow cardiac myosin regulatory light chain in heart failure
    Daniel F Pauly
    Clin Cardiol 34:10-1. 2011
  5. ncbi request reprint Cardiac function and heart failure
    Daniel F Pauly
    Division of Cardiovascular Medicine, University of Florida College of Medicine, Gainesville, Florida, USA
    J Am Coll Cardiol 45:24B-29B. 2005
  6. ncbi request reprint Synergistic polymorphisms of beta1 and alpha2C-adrenergic receptors and the influence on left ventricular ejection fraction response to beta-blocker therapy in heart failure
    Maximilian T Lobmeyer
    Department of Pharmacy Practice, University of Florida, Gainesville, FL 32610, USA
    Pharmacogenet Genomics 17:277-82. 2007
    ..We tested whether the ADRA2C insertion/deletion polymorphism was associated with beta-blocker response in heart failure, either alone or in combination with the ADRB1Arg389Gly polymorphism...
  7. ncbi request reprint Beta1-adrenergic receptor polymorphisms and left ventricular remodeling changes in response to beta-blocker therapy
    Steven G Terra
    Department of Pharmacy Practice, University of Florida College of Pharmacy, Gainesville, FL 32610, USA
    Pharmacogenet Genomics 15:227-34. 2005
    ..We hypothesized that polymorphisms at codon 389 (Arg389Gly) and 49 (Ser49Gly) in the beta1-adrenergic receptor (AR) gene were associated with LV reverse remodeling changes in response to beta-blocker therapy among heart failure patients...
  8. ncbi request reprint Arterial-wave reflections are increased in heart failure patients with a left-ventricular assist device
    Richard S Schofield
    Department of Veterans Affairs Medical Center, Gainesville, Florida, USA
    Am J Hypertens 20:622-8. 2007
    ..Although the treatment of HF via left-ventricular assist device (LVAD) placement has recently become widespread, the effects of LVAD therapy on central arterial pulse-wave reflections are unknown...
  9. ncbi request reprint Initial heart rate and systolic blood pressure predict outcomes in chronic heart failure patients who are evaluated for cardiac transplant
    Juan M Aranda
    University of Florida College of Medicine, Department of Medicine, Division of Cardiovascular Medicine, Gainesville, Florida, USA
    Clin Cardiol 30:282-7. 2007
    ..We sought to determine whether an initial hemodynamic profile of HR and SBP could be used to predict outcomes in chronic heart failure patients evaluated for Htx...
  10. pmc Multimarker approach predicts adverse cardiovascular events in women evaluated for suspected ischemia: results from the National Heart, Lung, and Blood Institute-sponsored Women's Ischemia Syndrome Evaluation
    Christopher B Arant
    Division of Cardiovascular Medicine, University of Florida College of Medicine, Gainesville, Florida, USA
    Clin Cardiol 32:244-50. 2009
    ..Inflammatory marker and hemoglobin levels (eg biomarkers) considered separately, predict adverse events in selected populations...
  11. doi request reprint Tricuspid annular motion as a predictor of severe right ventricular failure after left ventricular assist device implantation
    Sarinya Puwanant
    Division of Cardiovascular Medicine, Department of Internal Medicine, University of Florida, Gainesville, Florida, USA
    J Heart Lung Transplant 27:1102-7. 2008
    ..We sought to determine pre-operative right heart echocardiographic predictors of post-LVAD severe RV failure...
  12. ncbi request reprint beta-Adrenergic receptor polymorphisms and responses during titration of metoprolol controlled release/extended release in heart failure
    Steven G Terra
    Department of Pharmacy Practice, University of Florida, Gainsville, FL 32610, USA
    Clin Pharmacol Ther 77:127-37. 2005
    ..We also tested whether polymorphisms in the beta(2)-adrenergic receptor, G-protein alpha s subunit (G(s)alpha), and cytochrome P450 (CYP) 2D6 genes or S-metoprolol plasma concentrations were associated with beta-blocker tolerability...
  13. ncbi request reprint Discordant beta-blocker effects on clinic, ambulatory, resting, and exercise hemodynamics in patients with hypertension
    Amber L Beitelshees
    Department of Pharmacy Practice, College of Pharmacy, University of Florida, Gainesville, Florida 32610 0486, USA
    Pharmacotherapy 26:1247-54. 2006
    ....
  14. ncbi request reprint Managing the post-left ventricular assist device patient
    Charles T Klodell
    Department of Surgery, University of Florida, Gainesville, FL 32610, USA
    Congest Heart Fail 12:41-5. 2006
    ..Key issues following the implantation of assist devices include the prevention of right ventricular failure, appropriate pharmacologic management, prevention and management of infection, and detection and treatment of device dysfunction...
  15. ncbi request reprint Sustained restoration of autonomic balance with long- but not short-acting metoprolol in patients with heart failure
    Christina L Aquilante
    Department of Pharmacy Practice, University of Florida College of Pharmacy, Gainesville, 32610, USA
    J Card Fail 12:171-6. 2006
    ..The purpose of this study was to compare the effects of immediate-release (IR) metoprolol and extended-release (XL) metoprolol on measures of heart rate variability in chronic systolic heart failure patients...
  16. ncbi request reprint Relation of beta(2)-adrenoceptor haplotype to risk of death and heart transplantation in patients with heart failure
    Jaekyu Shin
    College of Pharmacy, Gainesville, Florida, USA
    Am J Cardiol 99:250-5. 2007
    ..In conclusion, ADRB2 Arg16Gln27 haplotype may significantly increase the risk of adverse outcomes in patients with HF receiving contemporary HF pharmacotherapy...
  17. ncbi request reprint Cardiac transplantation in patients with anti-phospholipid antibodies
    Richard S Schofield
    Department of Veterans Affairs Medical Center, Gainesville, Florida, USA
    J Heart Lung Transplant 26:299-301. 2007
    ....
  18. doi request reprint Incidence, predictors, and outcomes of cardiac pacing after cardiac transplantation: an 11-year retrospective analysis
    Gregory W Woo
    Division of Cardiovascular Medicine, University of Florida College of Medicine, Gainesville, Florida 32610 0277, USA
    Transplantation 85:1216-8. 2008
    ..001). Approximately one fourth of cardiac transplant patients require permanent pacing. Surgical technique is a major predictor of who will require permanent pacing after cardiac transplantation...
  19. doi request reprint Constrictive pericarditis presenting as a calcified anterior cardiac mass
    Richard S Schofield
    Division of Cardiovascular Medicine, University of Florida, Gainesville, Florida, USA
    Ann Thorac Surg 87:1597-9. 2009
    ..Upon diagnosis of constrictive pericarditis, the patient underwent pericardectomy and resection of the mass. He is well 6 months postoperatively, with complete resolution of his heart failure symptoms...
  20. ncbi request reprint Pharmacokinetics and CYP2D6 genotypes do not predict metoprolol adverse events or efficacy in hypertension
    Issam Zineh
    Department of Pharmacy Practice, University of Florida, Gainesville, FL 32610, USA
    Clin Pharmacol Ther 76:536-44. 2004
    ..We investigated whether metoprolol plasma concentrations, CYP2D6 polymorphisms, or genotype-derived phenotype was associated with adverse effects or efficacy in patients with hypertension...
  21. pmc Effect of cytochrome P450 3A5 genotype on atorvastatin pharmacokinetics and its interaction with clarithromycin
    Jaekyu Shin
    College of Pharmacy and Center for Pharmacogenomics, University of Florida, Health Science Center, Gainesville, FL 32610 0486, USA
    Pharmacotherapy 31:942-50. 2011
    ..35, p=0.049). Conclusion. Our data suggest that the CYP3A5 genotype has minimal effects on the pharmacokinetic parameters of atorvastatin and its interaction with clarithromycin; these effects are unlikely to be clinically significant...
  22. ncbi request reprint Atrial fibrillation as a cause of left ventricular dysfunction after cardiac transplantation
    Gregory W Woo
    Division of Cardiovascular Medicine, University of Florida College of Medicine, Gainesville, Florida, USA
    J Heart Lung Transplant 25:131-3. 2006
    ..The onset of atrial fibrillation years after a heart transplant is not necessarily an indication of rejection. Aggressive rate control and restoration of normal sinus rhythm may improve allograft function in such cases...
  23. ncbi request reprint Magnetic resonance imaging of primary cardiac lymphoma
    Matheen A Khuddus
    Division of Cardiovascular Medicine, University of Florida College of Medicine, Gainesville, FL 32610, USA
    Clin Cardiol 30:144-5. 2007
  24. ncbi request reprint Coronary microvascular reactivity is only partially predicted by atherosclerosis risk factors or coronary artery disease in women evaluated for suspected ischemia: results from the NHLBI Women's Ischemia Syndrome Evaluation (WISE)
    Timothy R Wessel
    University of Florida, Division of Cardiovascular Medicine, Gainesville, FL 32610 0277, USA
    Clin Cardiol 30:69-74. 2007
    ..Accordingly, the relationship between adenosine-related microvascular coronary reactivity and risk factors in symptomatic women evaluated for suspected ischemia remains uncertain...
  25. ncbi request reprint Dobutamine-related asthma in a patient awaiting cardiac transplantation: the eosinophilic dilemma
    Juan M Aranda
    Division of Cardiovascular Medicine, Shands Hospital, University of Florida, Gainesville, Florida 32610, USA
    J Heart Lung Transplant 23:260-1. 2004
    ..Once the patient was switched to an alternative inotrope, milrinone, the eosinophil count returned to normal, and the asthma exacerbation resolved...
  26. ncbi request reprint Management of heart failure after cardiac resynchronization therapy: integrating advanced heart failure treatment with optimal device function
    Juan M Aranda
    Division of Cardiovascular Medicine, College of Medicine, University of Florida Health Science Center, Gainesville, Florida, USA
    J Am Coll Cardiol 46:2193-8. 2005
    ..This algorithm represents a new, comprehensive, collaborative approach between the HF and electrophysiology specialists to further improve and sustain outcomes in the field of CRT...
  27. ncbi request reprint Early outcomes of a care coordination-enhanced telehome care program for elderly veterans with chronic heart failure
    Richard S Schofield
    Cardiology Section, Rehabilitation Outcomes Research Center, Department of Veterans Affairs Medical Center, Gainesville, Florida, USA
    Telemed J E Health 11:20-7. 2005
    ..Our nurse-directed, care coordinated home telehealth management program was associated with improved early outcomes in a group of elderly male veterans with chronic HF...
  28. ncbi request reprint QRS duration variability in patients with heart failure
    Juan M Aranda
    Division of Cardiovascular Medicine, The Department of Medicine, and Compute Science Section, University of Health Science Center, Gainesville, Florida 32610 0395, USA
    Am J Cardiol 90:335-7. 2002
  29. ncbi request reprint Percutaneous coronary intervention versus medical therapy for coronary allograft vasculopathy. One center's experience
    Juan M Aranda
    Division of Cardiovascular Medicine, University of Florida College of Medicine, Gainesville, USA
    J Heart Lung Transplant 21:860-6. 2002
    ..We compared clinical outcomes in heart transplant recipients with coronary allograft vasculopathy who were treated either with percutaneous coronary intervention or with aggressive medical therapy alone...
  30. ncbi request reprint Sustained use of nesiritide to aid in bridging to heart transplant
    James A Hill
    Heart Failure Transplantation Program, Division of Cardiology, University of Florida, Gainesville, Florida, USA
    Clin Cardiol 26:211-4. 2003
    ..This suggests that new strategies for pretransplant management may be needed...
  31. ncbi request reprint Comparison of dobutamine versus milrinone therapy in hospitalized patients awaiting cardiac transplantation: a prospective, randomized trial
    Juan M Aranda
    University of Florida College of Medicine, Division of Cardiovascular Medicine, the University of Florida Shands Transplant Center, Gainesville, FL 32610 0395, USA
    Am Heart J 145:324-9. 2003
    ..The costs and effectiveness of these drugs have yet to be compared in a prospective, randomized study...
  32. pmc In women with symptoms of cardiac ischemia, nonobstructive coronary arteries, and microvascular dysfunction, angiotensin-converting enzyme inhibition is associated with improved microvascular function: A double-blind randomized study from the National Hea
    Daniel F Pauly
    Division of Cardiovascular Medicine, University of Florida, Gainesville, USA
    Am Heart J 162:678-84. 2011
    ..Although microvascular dysfunction has been suggested to explain this syndrome and recently was found to predict adverse outcomes, the mechanisms and treatments remain unclear...
  33. pmc Simplified method for determination of clarithromycin in human plasma using protein precipitation in a 96-well format and liquid chromatography-tandem mass spectrometry
    Jaekyu Shin
    College of Pharmacy, University of Florida, Gainesville, FL 32610, USA
    J Chromatogr B Analyt Technol Biomed Life Sci 871:130-4. 2008
    ..The method is rapid, simple, precise and directly applicable to clarithromycin pharmacokinetic studies...
  34. ncbi request reprint Vascular effects of sildenafil in hypertensive cardiac transplant recipients
    Richard S Schofield
    Division of Cardiovascular Medicine and Shands Transplant Center, University of Florida College of Medicine, Gainesville, Florida 32610, USA
    Am J Hypertens 16:874-7. 2003
    ..Sildenafil is commonly used in the treatment of erectile dysfunction in hypertensive male cardiac transplant recipients (CTR); however, little is known about the vascular effects of sildenafil in these patients...
  35. ncbi request reprint Beta 1-adrenergic receptor polymorphisms and antihypertensive response to metoprolol
    Julie A Johnson
    Department of Pharmacy Practice, College of Pharmacy, University of Florida, Gainesville, 32610, USA
    Clin Pharmacol Ther 74:44-52. 2003
    ..We tested the hypothesis that 2 common polymorphisms in the gene for beta(1)-adrenergic receptor are associated with antihypertensive response to metoprolol in patients with uncomplicated hypertension...
  36. ncbi request reprint Anti-CD20 monoclonal antibody (rituximab) therapy for acute cardiac humoral rejection: a case report
    Juan M Aranda
    Department of Medicine, Division of Cardiovascular Medicine, University of Florida College of Medicine, Gainesville, FL 32610, USA
    Transplantation 73:907-10. 2002
    ..One year posttransplant, the patient is rejection-free, with normal left ventricular systolic function and coronary arteries...
  37. ncbi request reprint Correction of the enzymatic and functional deficits in a model of Pompe disease using adeno-associated virus vectors
    Thomas J Fraites
    Powell Gene Therapy Center, University of Florida College of Medicine, Gainesville, Florida 32610, USA
    Mol Ther 5:571-8. 2002
    ....
  38. pmc Association between the severity of angiographic coronary artery disease and paraoxonase gene polymorphisms in the National Heart, Lung, and Blood Institute-sponsored Women's Ischemia Syndrome Evaluation (WISE) study
    Qi Chen
    Department of Human Genetics, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA 15261, USA
    Am J Hum Genet 72:13-22. 2003
    ..26-10.68; P=.017) for PON2 codon 311 Cys/Cys. Our data indicate that the severity of CAD, in terms of the number of diseased vessels, may be affected by common genetic variation in the PON gene cluster, on chromosome 7...
  39. ncbi request reprint Transcriptional signals of T-cell and corticosteroid-sensitive genes are associated with future acute cellular rejection in cardiac allografts
    Mandeep R Mehra
    Division of Cardiology, University of Maryland School of Medicine, Baltimore, Maryland 21201, USA
    J Heart Lung Transplant 26:1255-63. 2007
    ..Profiling mRNA levels of 11 informative genes expressed by circulating immune effector cells identifies cardiac allograft recipients at low risk for current moderate-severe acute cellular rejection (ACR)...
  40. doi request reprint Design of a phase 1/2 trial of intracoronary administration of AAV1/SERCA2a in patients with heart failure
    Roger J Hajjar
    Mount Sinai School of Medicine, New York, New York 10029, USA
    J Card Fail 14:355-67. 2008
    ..Prior animal and human studies have documented decreased expression of SERCA2a, a major cardiac calcium cycling protein, as a major defect found in HF...
  41. ncbi request reprint Genetic variation in lectin-like oxidized low-density lipoprotein receptor 1 (LOX1) gene and the risk of coronary artery disease
    Qi Chen
    Department of Human Genetics, University of Pittsburgh, PA 15261, USA
    Circulation 107:3146-51. 2003
    ..We examined the association of 3 polymorphisms in the lectin-like oxidized LDL receptor-1 (LOX1 or OLR1) gene with coronary artery disease in the Women's Ischemia Syndrome Evaluation (WISE) study population...
  42. ncbi request reprint APOE polymorphism and angiographic coronary artery disease severity in the Women's Ischemia Syndrome Evaluation (WISE) study
    Qi Chen
    Department of Human Genetics, Graduate School of Public Health, University of Pittsburgh, 130 De Soto Street, Pittsburgh, PA 15261, USA
    Atherosclerosis 169:159-67. 2003
    ..These data support the hypothesis that the APOE*4 allele is an independent risk factor not only for the presence of CAD and hyperlipidemia, but also for the angiographic severity of CAD in white women with a family history of disease...
  43. ncbi request reprint Estrogen and different aspects of vascular disease in women and men
    Carl J Pepine
    Circ Res 99:459-61. 2006
  44. doi request reprint Clinical implications and longitudinal alteration of peripheral blood transcriptional signals indicative of future cardiac allograft rejection
    Mandeep R Mehra
    Division of Cardiology, University of Maryland School of Medicine, Baltimore, Maryland 21201, USA
    J Heart Lung Transplant 27:297-301. 2008
    ..We have previously demonstrated that a peripheral blood transcriptional profile using 11 distinct genes predicts onset of cardiac allograft rejection weeks to months prior to the actual event...
  45. ncbi request reprint Characterization and prognostic value of persistent hyponatremia in patients with severe heart failure in the ESCAPE Trial
    Mihai Gheorghiade
    Division of Cardiology, Northwestern University, Feinberg School of Medicine, 201 E Huron Street, Chicago, IL 60611, USA
    Arch Intern Med 167:1998-2005. 2007
    ..To our knowledge, the association of hyponatremia with outcomes has not been evaluated in the context of in-hospital clinical course including central hemodynamics and changes in serum sodium level...
  46. doi request reprint Cardiorenal interactions: insights from the ESCAPE trial
    Anju Nohria
    Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts, USA
    J Am Coll Cardiol 51:1268-74. 2008
    ....