Pankaj Jay Pasricha

Summary

Affiliation: University of Texas Medical Branch
Country: USA

Publications

  1. ncbi request reprint NOTES: a gastroenterologist's perspective
    Pankaj Jay Pasricha
    Center for Endoscopic Research, Training and Innovation CERTAIN, University of Texas Medical Branch, 4 106 McCullough Building, 301 University Boulevard, Galveston, TX 77555 0764, USA
    Gastrointest Endosc Clin N Am 17:611-6, viii-ix. 2007
  2. ncbi request reprint Neurolytic Approaches for the Treatment of Pain in Patients with Chronic Pancreatitis
    Manoop S Bhutani
    Division of Gastroenterology and Hepatology, University of Texas Medical Branch, 4 106 McCullough Building, 301 University Boulevard, Galveston, TX 77555 0764, USA
    Curr Treat Options Gastroenterol 6:375-379. 2003
  3. ncbi request reprint Endoscopic therapy for GERD: is the evidence for efficacy any stronger?
    Pankaj J Pasricha
    University of Texas Medical Branch, 4 106 McCullough Building, 301 University Boulevard, Galveston, TX 77555 0764, USA
    Curr Treat Options Gastroenterol 9:59-68. 2006
  4. pmc The role of mast cells in the pathogenesis of pain in chronic pancreatitis
    Willemijntje A Hoogerwerf
    Enteric Neuromuscular Disorders and Pain Laboratory, Division of Gastroenterology and Hepatology, University of Texas Medical Branch, 301 University Boulevard, Galveston, TX 77555 0764, USA
    BMC Gastroenterol 5:8. 2005
  5. ncbi request reprint Therapeutic upper endoscopy
    P J Pasricha
    Division of Gastroenterology and Hepatology, University of Texas Medical Branch, Galveston, TX 77555 0764, USA
    Gastrointest Endosc Clin N Am 10:81-8, vi. 2000
  6. ncbi request reprint Novel surgical approaches to fecal incontinence: neurostimulation and artificial anal sphincter
    Xiaotuan Zhao
    Division of Gastroenterology and Hepatology, University of Texas Medical Branch, 4 106 McCullough Building, 301 University Boulevard, Galveston TX 77555 0764, USA
    Curr Gastroenterol Rep 5:419-24. 2003
  7. ncbi request reprint Desperately seeking serotonin... A commentary on the withdrawal of tegaserod and the state of drug development for functional and motility disorders
    Pankaj Jay Pasricha
    University of Texas Medical Branch, Gasveston, TX 77555, USA
    Gastroenterology 132:2287-90. 2007
  8. ncbi request reprint Esophageal infarction
    Rami Hawari
    Pankaj J Pasricha, MD University of Texas Medical Branch, Division of Gastroenterology, Internal Medicine Department, 301 University Boulevard, Galveston, TX 77555, USA
    Curr Treat Options Gastroenterol 10:57-60. 2007
  9. ncbi request reprint Drug Insight: from disturbed motility to disordered movement--a review of the clinical benefits and medicolegal risks of metoclopramide
    P Jay Pasricha
    Division of Gastroenterology and Hepatology, University of Texas Medical Branch, Galveston, TX 77555, USA
    Nat Clin Pract Gastroenterol Hepatol 3:138-48. 2006
  10. ncbi request reprint Enhanced excitability and suppression of A-type K+ current of pancreas-specific afferent neurons in a rat model of chronic pancreatitis
    Guang Yin Xu
    Div of Gastroenterology and Hepatology, Dept of Internal Medicine, Univ of Texas Medical Branch, Galveston, Texas 77555, USA
    Am J Physiol Gastrointest Liver Physiol 291:G424-31. 2006

Collaborators

Detail Information

Publications60

  1. ncbi request reprint NOTES: a gastroenterologist's perspective
    Pankaj Jay Pasricha
    Center for Endoscopic Research, Training and Innovation CERTAIN, University of Texas Medical Branch, 4 106 McCullough Building, 301 University Boulevard, Galveston, TX 77555 0764, USA
    Gastrointest Endosc Clin N Am 17:611-6, viii-ix. 2007
    ..In this article I will discuss the implications of this paradigm shift and suggest strategies for both gastroenterologists and surgeons that will allow us to test its full potential...
  2. ncbi request reprint Neurolytic Approaches for the Treatment of Pain in Patients with Chronic Pancreatitis
    Manoop S Bhutani
    Division of Gastroenterology and Hepatology, University of Texas Medical Branch, 4 106 McCullough Building, 301 University Boulevard, Galveston, TX 77555 0764, USA
    Curr Treat Options Gastroenterol 6:375-379. 2003
    ..In addition, the lack of uniform improvement with any technique underscores the need for applying a multidisciplinary approach to these patients, as should be the case for any chronic pain disorder...
  3. ncbi request reprint Endoscopic therapy for GERD: is the evidence for efficacy any stronger?
    Pankaj J Pasricha
    University of Texas Medical Branch, 4 106 McCullough Building, 301 University Boulevard, Galveston, TX 77555 0764, USA
    Curr Treat Options Gastroenterol 9:59-68. 2006
    ..This review will summarize the available evidence and provide tentative conclusions about the current and evolving role of endoscopic antireflux therapy...
  4. pmc The role of mast cells in the pathogenesis of pain in chronic pancreatitis
    Willemijntje A Hoogerwerf
    Enteric Neuromuscular Disorders and Pain Laboratory, Division of Gastroenterology and Hepatology, University of Texas Medical Branch, 301 University Boulevard, Galveston, TX 77555 0764, USA
    BMC Gastroenterol 5:8. 2005
    ..We explored our hypothesis further using an experimental model of trinitrobenzene sulfonic acid (TNBS) -induced chronic pancreatitis in both wild type (WT) and mast cell deficient mice (MCDM)...
  5. ncbi request reprint Therapeutic upper endoscopy
    P J Pasricha
    Division of Gastroenterology and Hepatology, University of Texas Medical Branch, Galveston, TX 77555 0764, USA
    Gastrointest Endosc Clin N Am 10:81-8, vi. 2000
    ..The invention and implementation of these changes, however, is dependent on improvements in technology and the creation of an enlightened cadre of endoscopists with the knowledge and ability to be effective translational scientists...
  6. ncbi request reprint Novel surgical approaches to fecal incontinence: neurostimulation and artificial anal sphincter
    Xiaotuan Zhao
    Division of Gastroenterology and Hepatology, University of Texas Medical Branch, 4 106 McCullough Building, 301 University Boulevard, Galveston TX 77555 0764, USA
    Curr Gastroenterol Rep 5:419-24. 2003
    ..In this article we discuss these techniques and review their rationale, mechanisms of action, indications, outcomes, and complications...
  7. ncbi request reprint Desperately seeking serotonin... A commentary on the withdrawal of tegaserod and the state of drug development for functional and motility disorders
    Pankaj Jay Pasricha
    University of Texas Medical Branch, Gasveston, TX 77555, USA
    Gastroenterology 132:2287-90. 2007
  8. ncbi request reprint Esophageal infarction
    Rami Hawari
    Pankaj J Pasricha, MD University of Texas Medical Branch, Division of Gastroenterology, Internal Medicine Department, 301 University Boulevard, Galveston, TX 77555, USA
    Curr Treat Options Gastroenterol 10:57-60. 2007
    ..Ischemia due to hypoperfusion state is thought to play a central role in the pathogenesis. The treatment is supportive with acid suppression and gastrointestinal rest. Mortality is high due to comorbid conditions...
  9. ncbi request reprint Drug Insight: from disturbed motility to disordered movement--a review of the clinical benefits and medicolegal risks of metoclopramide
    P Jay Pasricha
    Division of Gastroenterology and Hepatology, University of Texas Medical Branch, Galveston, TX 77555, USA
    Nat Clin Pract Gastroenterol Hepatol 3:138-48. 2006
    ....
  10. ncbi request reprint Enhanced excitability and suppression of A-type K+ current of pancreas-specific afferent neurons in a rat model of chronic pancreatitis
    Guang Yin Xu
    Div of Gastroenterology and Hepatology, Dept of Internal Medicine, Univ of Texas Medical Branch, Galveston, Texas 77555, USA
    Am J Physiol Gastrointest Liver Physiol 291:G424-31. 2006
    ....
  11. ncbi request reprint Quality versus quantity: outcomes after achalasia surgery
    P J Pasricha
    Division of Gastroenterology and Hepatology, University of Texas Medical Branch, 4 106 McCullough Building, 301 University Boulevard, Galveston, TX 77555 0764, United States
    Dig Liver Dis 38:551-3. 2006
  12. ncbi request reprint Submucosal endoscopic esophageal myotomy: a novel experimental approach for the treatment of achalasia
    P J Pasricha
    Divison of Gastroenterology, University of Texas Medical Branch at Galveston, Galveston, Texas 77555 0764, USA
    Endoscopy 39:761-4. 2007
    ..We hypothesized that we could perform a safe and robust myotomy by working in the submucosal space, accessed from the esophageal lumen...
  13. ncbi request reprint Transient receptor potential vanilloid 1 mediates hyperalgesia and is up-regulated in rats with chronic pancreatitis
    Guang Yin Xu
    Division of Gastroenterology and Hepatology, Department of Internal Medicine, University of Texas Medical Branch, Galveston, Texas 77555, USA
    Gastroenterology 133:1282-92. 2007
    ..Our aim was to study the role of the transient receptor potential vanilloid 1 (TRPV1), a key integrator of noxious stimuli, in the pathogenesis of pancreatic pain in a rat model of CP...
  14. pmc Anatomical and functional characterization of a duodeno-pancreatic neural reflex that can induce acute pancreatitis
    Cuiping Li
    Division of Gastroenterology and Hepatology, Stanford University, Stanford, CA, USA
    Am J Physiol Gastrointest Liver Physiol 304:G490-500. 2013
    ..It also proves a previously unexamined mechanism by which alcohol can induce pancreatitis, which is novel both in terms of the site (duodenum), process (neurogenic), and receptor (TRPA1)...
  15. doi request reprint A rat model of chronic gastric sensorimotor dysfunction resulting from transient neonatal gastric irritation
    Lian Sheng Liu
    Division of Gastroenterology and Hepatology, Department of Medicine, Stanford University School of Medicine, Stanford, California 94305 5187, USA
    Gastroenterology 134:2070-9. 2008
    ....
  16. pmc Systemic administration of anti-NGF increases A-type potassium currents and decreases pancreatic nociceptor excitability in a rat model of chronic pancreatitis
    Yaohui Zhu
    Department of Medicine, Division of Gastroenterology and Hepatology, Stanford University School of Medicine, Stanford, California 94305, USA
    Am J Physiol Gastrointest Liver Physiol 302:G176-81. 2012
    ..No significant differences were seen among those. These findings emphasize a key role for NGF in maintaining neuronal excitability in CP specifically via downregulation of I(A) by as yet unknown mechanisms...
  17. doi request reprint Nerve growth factor modulates TRPV1 expression and function and mediates pain in chronic pancreatitis
    Yaohui Zhu
    Division of Gastroenterology and Hepatology, Department of Medicine, Stanford University School of Medicine, Stanford, California 94305, USA
    Gastroenterology 141:370-7. 2011
    ..We hypothesized that nerve growth factor (NGF) plays a key role in this process via its effects on the transient receptor potential vanilloid 1, TRPV1...
  18. ncbi request reprint Immediate endoscopic closure of colon perforation by using a prototype endoscopic suturing device: feasibility and outcome in a porcine model (with video)
    Binh V Pham
    Center for Endoscopic Research, Training, and Innovation CERTAIN, Department of Internal Medicine, University of Texas Medical Branch, 301 University Boulevard, Galveston, TX 77555, USA
    Gastrointest Endosc 64:113-9. 2006
    ..Surgical closure is the standard of care. Immediate endoluminal closure of a perforation would avoid the morbidity and mortality associated with general anesthesia, laparotomy, and surgical repair...
  19. pmc Evaluation of ES-derived neural progenitors as a potential source for cell replacement therapy in the gut
    Valentina Sasselli
    Division of Gastroenterology and Hepatology, University of Texas Medical Branch, Galveston, TX, USA
    BMC Gastroenterol 12:81. 2012
    ..In this study, we investigated the ability of ES cells to respond to environmental cues derived from the ENS and related tissues, both in vitro and in vivo...
  20. doi request reprint Feasibility of gastric electrical stimulation by percutaneous endoscopic transgastric electrodes
    Hanaa S Sallam
    Division of Gastroenterology, Department of Internal Medicine, University of Texas Medical Branch, Galveston, Texas 77555 0632, USA
    Gastrointest Endosc 68:754-9. 2008
    ..Both these indications have involved surgical placement of gastric electrodes, which adds to the complexity and cost of the procedure. Endoscopic placement is therefore an attractive alternative approach for this therapy...
  21. pmc Substance P and calcitonin gene related peptide mediate pain in chronic pancreatitis and their expression is driven by nerve growth factor
    Liansheng Liu
    Division of Gastroenterology and Hepatology, Stanford University Medical Center, Stanford, CA, USA
    JOP 12:389-94. 2011
    ..Calcitonin gene-related peptide (CGRP), substance P and nerve growth factor play an important role in inflammatory pain in various somatic pain models but their role in chronic pancreatitis has not been well studied...
  22. doi request reprint The D2/D3 agonist PD128907 (R-(+)-trans-3,4a,10b-tetrahydro-4-propyl-2H,5H-[1]benzopyrano[4,3-b]-1,4-oxazin-9-ol) inhibits stimulated pyloric relaxation and spontaneous gastric emptying
    Purna Kashyap
    Enteric Neuromuscular Disorders and Pain Laboratory, Division of Gastroenterology and Hepatology, University of Texas Medical Branch, Galveston, TX, USA
    Dig Dis Sci 54:57-62. 2009
    ..The aim of this study was to investigate the modulation of gastric motility by the dopamine-3 receptor (D3R)...
  23. pmc Divergent fate and origin of neurosphere-like bodies from different layers of the gut
    Laren Becker
    Department of Medicine, Division of Gastroenterology and Hepatology, Stanford University, Stanford, California 94305, USA
    Am J Physiol Gastrointest Liver Physiol 302:G958-65. 2012
    ..NLBs from the myenteric plexus layer contain more neural crest-derived ENSCs while those from submucosal plexus appear more heterogeneous, likely containing a population of mesenchymal stem cells...
  24. ncbi request reprint Molecular and behavioral changes in nociception in a novel rat model of chronic pancreatitis for the study of pain
    John H Winston
    Division of Gastroenterology and Hepatology, Department of Internal Medicine, The University of Texas Medical Branch, 4 106 McCullough Building, 301 University Boulevard, Galveston TX 77555 0764, USA
    Pain 117:214-22. 2005
    ..This model has considerable construct, face and predictive validity for the human condition. It is of importance for the study of the pathogenesis of pain in this condition and can facilitate the development of new therapeutic options...
  25. ncbi request reprint Neural stem cells for the treatment of disorders of the enteric nervous system: strategies and challenges
    Maria Adelaide Micci
    Enteric Neuromuscular Disorders and Pain Laboratory, Division of Gastroenterology and Hepatology, University of Texas Medical Branch, Galveston, Texas 77555 0764, USA
    Dev Dyn 236:33-43. 2007
    ..We hope that our review will encourage new investigators in entering this field of research ad contribute to our knowledge of the potentials of NSC and other cells for the treatment of gastrointestinal dysmotility...
  26. ncbi request reprint The vanilloid receptor initiates and maintains colonic hypersensitivity induced by neonatal colon irritation in rats
    John Winston
    Enteric Neuromuscular Disorders and Pain Laboratory, Division of Gastroenterology and Hepatology, Department of Internal Medicine, University of Texas Medical Branch, Galveston 77555 0764, USA
    Gastroenterology 132:615-27. 2007
    ....
  27. pmc Diabetes induces sex-dependent changes in neuronal nitric oxide synthase dimerization and function in the rat gastric antrum
    Pandu R R Gangula
    Division of Gastroenterology and Hepatology, Department of Internal Medicine, The University of Texas Medical Branch, Galveston, Texas 77555, USA
    Am J Physiol Gastrointest Liver Physiol 292:G725-33. 2007
    ..Furthermore, diabetes seems to affect the nitrergic system to a greater extent in females than in males. Together, these changes may account for the greater vulnerability of females to diabetic gastric dysfunction...
  28. pmc Stem cell transplantation in neurodegenerative disorders of the gastrointestinal tract: future or fiction?
    Subhash Kulkarni
    Division of Gastroenterology and Hepatology, Stanford University, School of Medicine, Stanford, CA 94305, USA
    Gut 61:613-21. 2012
    ..This review summarises the current status of research in this field, identifies the major gaps in our knowledge and discusses the potential opportunities and hurdles for clinical application...
  29. pmc Gut-derived factors promote neurogenesis of CNS-neural stem cells and nudge their differentiation to an enteric-like neuronal phenotype
    Subhash Kulkarni
    Div of Gastroenterology and Hepatology, Stanford Univ School of Medicine, CA 94305, USA
    Am J Physiol Gastrointest Liver Physiol 301:G644-55. 2011
    ..Our results show that the gut microenvironment induces CNS-NSC to produce neurons that share some of the characteristics of classical enteric neurons, further supporting the therapeutic use of these cells for gastrointestinal disorders...
  30. ncbi request reprint The riddle, mystery, and enigma of gastroparesis
    Pankaj Jay Pasricha
    Division of Gastroenterology and Hepatology, Stanford University, Stanford, CA 94305 5187, USA
    J Support Oncol 5:368-70. 2007
  31. ncbi request reprint Going for the loop: a unique overtube for the difficult colonoscopy
    Rami Hawari
    Division of Gastroenterology and Hepatology, University of Texas Medical Branch 4 106 McCullough Building, 301 University Boulevard, Galveston, TX 77555 0764, USA
    J Clin Gastroenterol 41:138-40. 2007
    ..It also has potential other applications including enteroscopy, transgastric endoscopy and access to difficult regions of the upper gastrointestinal tract...
  32. ncbi request reprint The role of endoscopic ultrasound and endoscopic ultrasound-guided fine-needle aspiration in distinguishing pancreatic cystic lesions
    Bhavani Moparty
    Department of Medicine, University of Texas Medical Branch, Galveston, Texas
    Diagn Cytopathol 35:18-25. 2007
    ....
  33. pmc The endogenous hydrogen sulfide producing enzyme cystathionine-beta synthase contributes to visceral hypersensitivity in a rat model of irritable bowel syndrome
    Guang Yin Xu
    Division of Gastroenterology and Hepatology, Department of Internal Medicine, University of Texas Medical Branch, Galveston, Texas 77555 0655, USA
    Mol Pain 5:44. 2009
    ..Dorsal root ganglion (DRG) neurons innervating the colon were labeled by injection of DiI (1,1'-dioleyl-3,3,3',3-tetramethylindocarbocyanine methanesulfonate) into the colon wall...
  34. ncbi request reprint A novel shape-locking guide for prevention of sigmoid looping during colonoscopy
    Gottumukkala S Raju
    Center for Endoscopic Research Training and Innovation, University of Texas Medical Branch, Galveston, Texas 77555 0764, USA
    Gastrointest Endosc 59:416-9. 2004
    ..This report describes the design and operation of a new device that addresses this problem, together with preliminary preclinical experience with this use of this shape-locking guide (SG-1)...
  35. ncbi request reprint Trypsin mediates nociception via the proteinase-activated receptor 2: a potentially novel role in pancreatic pain
    Willemijntje A Hoogerwerf
    Enteric Neuromuscular Disorders and Pain Laboratory, Division of Gastroenterology and Hepatology, University of Texas Medical Branch, Galveston, Texas, USA
    Gastroenterology 127:883-91. 2004
    ..The pathogenesis of pain in pancreatitis remains poorly understood. We hypothesized that trypsin, a key inflammatory mediator in this condition, can also activate nociceptive neurons via the proteinase-activated receptor 2...
  36. ncbi request reprint Neural stem cell transplantation in the stomach rescues gastric function in neuronal nitric oxide synthase-deficient mice
    Maria Adelaide Micci
    Enteric Neuromuscular Disorders and Pain Laboratory, Division of Gastroenterology and Hepatology, University of Texas Medical Branch, Galveston, Texas 77555 0764, USA
    Gastroenterology 129:1817-24. 2005
    ..The aim of this study was to evaluate the effect of intrapyloric transplantation of neural stem cells (NSCs) on gastric emptying and pyloric function in nNOS-/- mice, a well-established genetic model of gastroparesis...
  37. ncbi request reprint Botulinum toxin for spastic GI disorders: a systematic review
    Xiaotuan Zhao
    Enteric Neuromuscular Disorders and Pain END Pain Program, Division of Gastroenterology and Hepatology, University of Texas Medical Branch, Galveston 77555, USA
    Gastrointest Endosc 57:219-35. 2003
  38. ncbi request reprint Origins and patterns of spontaneous and drug-induced canine gastric myoelectrical dysrhythmia
    L W Qian
    Department of Internal Medicine, Division of Gastroenterology, The University of Texas Medical Branch, Galveston, Texas 77555 0632, USA
    Dig Dis Sci 48:508-15. 2003
    ..Bradygastria is attributed to a decrease in the frequency of the normal pacemaker in the corpus. The prevalence of gastric dysrhythmia is different in different locations of the stomach and is highest in the distal antrum...
  39. ncbi request reprint Acute pancreatitis results in referred mechanical hypersensitivity and neuropeptide up-regulation that can be suppressed by the protein kinase inhibitor k252a
    John H Winston
    Enteric Neuromuscular Disorders and Pain Group, Division of Gastroenterology and Hepatology, Department of Internal Medicine, University of Texas Medical Branch, Galveston, Texas 77555, USA
    J Pain 4:329-37. 2003
    ..Treatment with the kinase inhibitor k252a suppressed the phosphorylation of trkA in the pancreas as well as reversed both the behavioral changes and the increase in neuropeptide expression associated with pancreatitis...
  40. doi request reprint Low ileocecal valve pressure is significantly associated with small intestinal bacterial overgrowth (SIBO)
    Bani Chander Roland
    Division of Gastroenterology and Hepatology, Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Dig Dis Sci 59:1269-77. 2014
    ..ICV dysfunction remains largely unexplored using standard technology. The wireless motility capsule (WMC) that evaluates pressure, pH, and temperature throughout the GI tract provides the ability to assess these parameters...
  41. doi request reprint Endoscopy 20 years into the future
    Pankaj Jay Pasricha
    Division of Gastroenterology and Hepatology, Johns Hopkins School of Medicine, Baltimore, Maryland 21224, USA
    Clin Gastroenterol Hepatol 11:119-22. 2013
    ..In this essay, I will describe some of what I believe to be the most important future developments with the greatest potential for impact across the spectrum of digestive disorders...
  42. doi request reprint Not your father's colonoscopy: a high-tech future for screening and surveillance of colorectal cancer
    Michael J Krier
    Division of Gastroenterology and Hepatology, Stanford University School of Medicine, 300 Pasteur Drive, Stanford, CA 94305 5187, USA
    Gastrointest Endosc Clin N Am 18:607-17, xi. 2008
    ....
  43. ncbi request reprint Images in clinical medicine. Eosinophilic esophagitis
    Rami Hawari
    University of Texas Medical Branch, Galveston, TX 77555, USA
    N Engl J Med 356:e20. 2007
  44. ncbi request reprint Biliary drainage by using stents without a central lumen: a pilot study
    Gottumukkala S Raju
    Center for Endoscopic Research, Training, and Innovation CERTAIN, Department of Medicine, University of Texas Medical Branch, University of Texas, Galveston, Texas, USA
    Gastrointest Endosc 63:317-20. 2006
    ..We hypothesized that the creation of pathways for fluid flow around the stent instead of through it would avoid this problem. The aim of our study was to report the development and the evaluation of a novel lumen-less stent...
  45. ncbi request reprint Pain and chronic pancreatitis: is it the plumbing or the wiring?
    Rajeswari Anaparthy
    Division of Gastroenterology and Hepatology, Stanford University School of Medicine, 300 Pasteur Drive, Alway Building, Room M211, Stanford, CA 94305, USA
    Curr Gastroenterol Rep 10:101-6. 2008
    ..In this review, we discuss the inherent limitations in our current therapies and try to identify new targets and approaches for the future, such as TRPV1, nerve growth factor-TrkA signaling, and perhaps protease activator receptor-2...
  46. ncbi request reprint Intraductal administration of an NK1 receptor antagonist attenuates the inflammatory response to retrograde infusion of radiological contrast in rats: implications for the pathogenesis and prevention of ERCP-induced pancreatitis
    Zhi jun He
    Department of Internal Medicine, Division of Gastroenterology and Hepatology, Enteric Neuromuscular Disorders and Pain Laboratory, University of Texas Medical Branch, Galveston, Texas 77555, USA
    Pancreas 27:e13-7. 2003
    ..AIMS Our aim was to evaluate the effectiveness of CP-96345, a NK1 receptor antagonist, in diminishing post-ERCP pancreatitis in a rat model...
  47. doi request reprint Clinical significance of quantitative assessment of rectoanal inhibitory reflex (RAIR) in patients with constipation
    Xiaohong Xu
    Division of Gastroenterology, University of Texas Medical Branch, Galveston, TX, USA
    J Clin Gastroenterol 42:692-8. 2008
    ..However, no quantitative analysis is currently available for the assessment of RAIR. The aim of this study was to evaluate the diagnostic value of quantitative assessment of RAIR in patients with constipation...
  48. ncbi request reprint Characterization of the neurotrophic response to acute pancreatitis
    Hiroki Toma
    Enteric Neuromuscular Disorders and Pain Laboratory, Department of Internal Medicine, Division of Gastroenterology and Hepatology, University of Texas Medical Branch, Galveston, Texas 77555, USA
    Pancreas 25:31-8. 2002
    ..Interesting preliminary data on changes in the neurotrophin system in various digestive diseases have recently begun to emerge...
  49. doi request reprint Endoscopic injection of skeletal muscle-derived cells augments gut smooth muscle sphincter function: implications for a novel therapeutic approach
    Pankaj J Pasricha
    Division of Gastroenterology and Hepatology, Stanford University, Stanford, California 94305 5187, USA
    Gastrointest Endosc 70:1231-7. 2009
    ..Sphincter function is a common problem in gastroenterology and leads to disorders such as GERD and fecal incontinence...
  50. pmc Gastroparesis and gastroparesis-like syndrome: response to therapy and its predictors
    Rajeswari Anaparthy
    University of Texas Medical Branch, Galveston, TX, USA
    Dig Dis Sci 54:1003-10. 2009
    ..The aim of this study was to identify the clinical or pathophysiological characteristics, if any, that may be helpful in predicting therapeutic response in this condition...
  51. ncbi request reprint Improvement of gastric motility with gastric electrical stimulation in STZ-induced diabetic rats
    Jinsong Liu
    Division of Gastroenterology, University of Texas Medical Branch, Galveston, Tex, USA
    Digestion 70:159-66. 2004
    ..The aims of this study were to observe whether gastric motility was impaired in streptozotocin (STZ)-induced diabetic rats and whether gastric electrical stimulation was able to restore the impaired motility...
  52. ncbi request reprint Feasibility of gastric electrical stimulation by use of endoscopically placed electrodes
    Xiaohong Xu
    Division of Gastroenterology, University of Texas Medical Branch, Galveston, Texas, USA
    Gastrointest Endosc 66:981-6. 2007
    ..New methods are needed for implanting GES electrodes in a safer and more feasible way...
  53. ncbi request reprint An unusual electrocardiogram artifact: what is its source?
    Nischita K Reddy
    Department of Neurology, The University of Texas Medical Branch, Galveston, TX 77555 0553, USA
    J Electrocardiol 38:337-9. 2005
    ..The patient had an implanted gastric electrical stimulation system for treating her diabetic gastroparesis. Recent DC shock for ventricular fibrillation during coronary angiography caused malfunction of the gastric pacemaker...
  54. ncbi request reprint A novel role of VIP in colonic motility function: induction of excitation-transcription coupling in smooth muscle cells
    Xuan Zheng Shi
    Department of Internal Medicine, Enteric Neuromuscular Disorders and Visceral Pain Center, Division of Gastroenterology, The University of Texas Medical Branch at Galveston, Galveston, Texas 77555, USA
    Gastroenterology 132:1388-400. 2007
    ..The aim of this study was to investigate whether the phosphorylation of CREB induces gene expression of the pore-forming alpha(1C) subunit of Ca(v)1.2 channels (L-type calcium channels), whose promoter has 2 binding sites for CREB...
  55. ncbi request reprint Women and irritable bowel syndrome: is the gain in pain mainly in the brain?
    Pandu R R Gangula
    J Gastroenterol Hepatol 21:343-4. 2006
  56. doi request reprint A systematic review of the efficacy of domperidone for the treatment of diabetic gastroparesis
    Aravind Sugumar
    Department of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota, USA
    Clin Gastroenterol Hepatol 6:726-33. 2008
    ..The literature on this subject varies considerably with respect to the methods and outcome measures, making a meta-analysis unfeasible...
  57. ncbi request reprint There is no role for ERCP in unexplained abdominal pain of pancreatic or biliary origin
    Pankaj Jay Pasricha
    Division of Gastroenterology and Hepatology, University of Texas Medical Branch, Galveston, Texas 77555 0764, USA
    Gastrointest Endosc 56:S267-72. 2002
  58. doi request reprint Preface. Gastrointestinal endoscopy has come a long way
    C Richard Boland
    GI Cancer Research Laboratory H 250 Baylor University Medical Center, 3500 Gaston Avenue, Dallas, TX 75246, USA
    Gastrointest Endosc Clin N Am 18:xv-xvi. 2008
  59. ncbi request reprint Optical biopsies, "bioendoscopy," and why the sky is blue: the coming revolution in gastrointestinal imaging
    Pankaj Jay Pasricha
    Gastroenterology 122:571-5. 2002
  60. ncbi request reprint The future of therapeutic endoscopy
    Pankaj Jay Pasricha
    Clin Gastroenterol Hepatol 2:286-9. 2004