Petros Papagerakis

Summary

Affiliation: University of Michigan
Country: USA

Publications

  1. pmc Innovative approaches to regenerate enamel and dentin
    Xanthippi Chatzistavrou
    Department of Orthodontics and Pediatric Dentistry, School of Dentistry, University of Michigan, Ann Arbor, MI 48109, USA
    Int J Dent 2012:856470. 2012
  2. pmc Identifying promoter elements necessary for enamelin tissue-specific expression
    Petros Papagerakis
    Department of Orthodontics and Pediatric Dentistry, University of Michigan School of Dentistry, Ann Arbor, Mich 48108, USA
    Cells Tissues Organs 189:98-104. 2009
  3. pmc Distal cis-regulatory elements are required for tissue-specific expression of enamelin (Enam)
    Yuanyuan Hu
    Department of Orthodontics and Pediatric Dentistry, University of Michigan School of Dentistry, Ann Arbor, MI 48108, USA
    Eur J Oral Sci 116:113-23. 2008
  4. pmc Circadian rhythms regulate amelogenesis
    Li Zheng
    Department of Orthodontics and Pediatric Dentistry, School of Dentistry, University of Michigan, Ann Arbor, MI, USA
    Bone 55:158-65. 2013
  5. pmc Molecular and circadian controls of ameloblasts
    Maria Athanassiou-Papaefthymiou
    Department of Orthodontics and Pediatric Medicine, Center for Computational Medicine and Bioinformatics, University of Michigan Schools of Dentistry and Medicine, Ann Arbor, MI 48109, USA
    Eur J Oral Sci 119:35-40. 2011
  6. pmc The tick tock of odontogenesis
    Li Zheng
    Department of Pediatric Dentistry, School of Dentistry, University of Michigan, Ann Arbor, MI, USA Department of Otolaryngology, Medical School, University of Michigan, Ann Arbor, MI, USA
    Exp Cell Res 325:83-9. 2014
  7. pmc Enamel defects and ameloblast-specific expression in Enam knock-out/lacz knock-in mice
    Jan C C Hu
    Department of Orthodontics and Pediatric Dentistry and Department of Biologic and Materials Sciences, University of Michigan School of Dentistry, Ann Arbor, Michigan 48108, USA
    J Biol Chem 283:10858-71. 2008
  8. doi request reprint Orai1 expression pattern in tooth and craniofacial ectodermal tissues and potential functions during ameloblast differentiation
    Li Zheng
    Department of Orthodontics and Pediatric Dentistry, School of Dentistry, University of Michigan, Ann Arbor, Michigan
    Dev Dyn 244:1249-58. 2015
  9. pmc Functions of KLK4 and MMP-20 in dental enamel formation
    Yuhe Lu
    Department of Biologic and Materials Sciences, University of Michigan School of Dentistry, 1011 North University, Ann Arbor, MI 48109 1078, USA
    Biol Chem 389:695-700. 2008
  10. doi request reprint Designing dental composites with bioactive and bactericidal properties
    Xanthippi Chatzistavrou
    Orthodontics and Pediatric Dentistry, School of Dentistry, University of Michigan, Ann Arbor, MI, USA Electronic address
    Mater Sci Eng C Mater Biol Appl 52:267-72. 2015

Research Grants

  1. Expression and Regulation of LEF-1 During Odontogenesis
    Petros Papagerakis; Fiscal Year: 2005

Collaborators

Detail Information

Publications17

  1. pmc Innovative approaches to regenerate enamel and dentin
    Xanthippi Chatzistavrou
    Department of Orthodontics and Pediatric Dentistry, School of Dentistry, University of Michigan, Ann Arbor, MI 48109, USA
    Int J Dent 2012:856470. 2012
    ....
  2. pmc Identifying promoter elements necessary for enamelin tissue-specific expression
    Petros Papagerakis
    Department of Orthodontics and Pediatric Dentistry, University of Michigan School of Dentistry, Ann Arbor, Mich 48108, USA
    Cells Tissues Organs 189:98-104. 2009
    ..In contrast, the 5.2-kb Enam-LacZ construct was sufficient to mimic the endogenous Enam ameloblast-specific expression pattern. Our study provides new insights into the molecular control of Enam cell- and stage-specific expression...
  3. pmc Distal cis-regulatory elements are required for tissue-specific expression of enamelin (Enam)
    Yuanyuan Hu
    Department of Orthodontics and Pediatric Dentistry, University of Michigan School of Dentistry, Ann Arbor, MI 48108, USA
    Eur J Oral Sci 116:113-23. 2008
    ..Our study provides new insights into regulatory mechanisms governing enamelin expression...
  4. pmc Circadian rhythms regulate amelogenesis
    Li Zheng
    Department of Orthodontics and Pediatric Dentistry, School of Dentistry, University of Michigan, Ann Arbor, MI, USA
    Bone 55:158-65. 2013
    ..Changes in clock gene expression patterns might result in significant alterations of enamel apposition and mineralization...
  5. pmc Molecular and circadian controls of ameloblasts
    Maria Athanassiou-Papaefthymiou
    Department of Orthodontics and Pediatric Medicine, Center for Computational Medicine and Bioinformatics, University of Michigan Schools of Dentistry and Medicine, Ann Arbor, MI 48109, USA
    Eur J Oral Sci 119:35-40. 2011
    ..Our study provides novel insights into the regulatory mechanisms sustaining ameloblast differentiation...
  6. pmc The tick tock of odontogenesis
    Li Zheng
    Department of Pediatric Dentistry, School of Dentistry, University of Michigan, Ann Arbor, MI, USA Department of Otolaryngology, Medical School, University of Michigan, Ann Arbor, MI, USA
    Exp Cell Res 325:83-9. 2014
    ..This review summarizes the current knowledge on the circadian controls of dental mineralized tissues development with a special emphasis on amelogenesis. ..
  7. pmc Enamel defects and ameloblast-specific expression in Enam knock-out/lacz knock-in mice
    Jan C C Hu
    Department of Orthodontics and Pediatric Dentistry and Department of Biologic and Materials Sciences, University of Michigan School of Dentistry, Ann Arbor, Michigan 48108, USA
    J Biol Chem 283:10858-71. 2008
    ..These results demonstrate ameloblast-specific expression of enamelin and reveal that enamelin is essential for proper enamel matrix organization and mineralization...
  8. doi request reprint Orai1 expression pattern in tooth and craniofacial ectodermal tissues and potential functions during ameloblast differentiation
    Li Zheng
    Department of Orthodontics and Pediatric Dentistry, School of Dentistry, University of Michigan, Ann Arbor, Michigan
    Dev Dyn 244:1249-58. 2015
    ..We also examined the effects of Orai1 down-regulation in ameloblast cell proliferation and differentiation...
  9. pmc Functions of KLK4 and MMP-20 in dental enamel formation
    Yuhe Lu
    Department of Biologic and Materials Sciences, University of Michigan School of Dentistry, 1011 North University, Ann Arbor, MI 48109 1078, USA
    Biol Chem 389:695-700. 2008
    ....
  10. doi request reprint Designing dental composites with bioactive and bactericidal properties
    Xanthippi Chatzistavrou
    Orthodontics and Pediatric Dentistry, School of Dentistry, University of Michigan, Ann Arbor, MI, USA Electronic address
    Mater Sci Eng C Mater Biol Appl 52:267-72. 2015
    ..The aim of this work was to fabricate and evaluate new antibacterial and bioactive composites capable of strictly controlling oral bacteria, enhancing apatite layer formation and retaining their mechanical properties...
  11. pmc Clinical significance of kallikrein-related peptidase-4 in oral cancer
    Petros Papagerakis
    Department of Pediatric Dentistry and Orthodontics, School of Dentistry, University of Michigan, Ann Arbor, MI, U S A Department of Computational Medicine and Bioinformatics, Medical School, University of Michigan, Ann Arbor, MI, U S A
    Anticancer Res 35:1861-6. 2015
    ..Therefore, this study provides supportive evidence in favor of a prognostic value for KLK4 in OSCC and suggests that KLK4 could serve as a potential therapeutic target in patients with oral cancer. ..
  12. doi request reprint Altered desmoplakin expression at transcriptional and protein levels provides prognostic information in human oropharyngeal cancer
    Silvana Papagerakis
    Laboratoire de Biologie Orofaciale et Pathologie, INSERM UMRS872, Universite Paris 7, Centre de Recherche des Cordeliers, Paris, 75006 France
    Hum Pathol 40:1320-9. 2009
    ..Characterizing DSP expression may improve evaluation risk of distant metastasis formation in oral cancer patients...
  13. pmc Oral epithelial stem cells - implications in normal development and cancer metastasis
    Silvana Papagerakis
    Department of Otolaryngology, Medical School, University of Michigan, Ann Arbor, MI, USA Department of Periodontics and Oral Medicine, School of Dentistry, University of Michigan, Ann Arbor, MI, USA Electronic address
    Exp Cell Res 325:111-29. 2014
    ..This review presents a brief overview of epithelium stem cells with implications in oral health, and the clinical implications of the CSC concept in OSCC metastatic dissemination. ..
  14. pmc Expression of clock proteins in developing tooth
    Li Zheng
    Department of Orthodontics and Pediatric Dentistry, School of Dentistry, University of Michigan, Ann Arbor, MI, USA
    Gene Expr Patterns 11:202-6. 2011
    ..Our data suggests that clock genes might be involved in the regulation of ameloblast and odontoblast functions, such as enamel and dentin protein secretion and matrix mineralization...
  15. pmc Increased fucosylation has a pivotal role in invasive and metastatic properties of head and neck cancer stem cells
    Vincenzo Desiderio
    Department of Otolaryngology, Medical School, University of Michigan, Ann Arbor, MI, USA Department of Experimental Medicine, Section of Biotechnology and Medical Histology and Embryology, Second University of Naples, Italy
    Oncotarget 6:71-84. 2015
    ..In addition, SLex may play a key role in CSC metastasis. Thus, inhibition of fucosylation may be used to block CSCs and metastatic spread. ..
  16. pmc In vitro cytokine release profile: predictive value for metastatic potential in head and neck squamous cell carcinomas
    Omar Shkeir
    Departments of Otolaryngology Head and Neck Surgery, University of Michigan, Ann Arbor, Michigan
    Head Neck 35:1542-50. 2013
    ..Head and neck squamous cell carcinomas (HNSCCs) have devastating morbidity rates with mortality mainly because of metastasis...
  17. doi request reprint Fabrication and characterization of bioactive and antibacterial composites for dental applications
    Xanthippi Chatzistavrou
    Orthodontics and Pediatric Dentistry, School of Dentistry, University of Michigan, Ann Arbor, MI, USA Electronic address
    Acta Biomater 10:3723-32. 2014
    ..This advanced composite made of Ag-BG incorporated into natural ECM possesses improved properties that may facilitate potential applications in tooth regeneration approaches. ..

Research Grants1

  1. Expression and Regulation of LEF-1 During Odontogenesis
    Petros Papagerakis; Fiscal Year: 2005
    ..Papagerakis for a successful career as a productive independent investigator. ..