Georgios I Papachristou

Summary

Affiliation: University of Pittsburgh
Country: USA

Publications

  1. doi request reprint Low serum adiponectin levels are associated with systemic organ failure in acute pancreatitis
    Arun Sharma
    Division of Gastroenterology, Hepatology and Nutrition, Department of Medicine, University of Pittsburgh, Pittsburgh, PA 15213, USA
    Pancreas 38:907-12. 2009
  2. ncbi request reprint Pharmacological therapy for acute pancreatitis: where are we now? where are we going?
    J J Easler
    University of Pittsburgh Medical Center, Pittsburgh, PA, USA
    Minerva Gastroenterol Dietol 58:365-76. 2012
  3. doi request reprint Epidermal growth factor serum levels and the 61 G/A polymorphism in patients with acute pancreatitis
    Georgios I Papachristou
    Department of Medicine, Division of Gastroenterology, Hepatology and Nutrition, University of Pittsburgh Medical Center, Presbyterian, M2 C Wing, 200 Lothrop Street, Pittsburgh, PA 15213, USA
    Dig Dis Sci 55:2676-80. 2010
  4. doi request reprint Comparison of BISAP, Ranson's, APACHE-II, and CTSI scores in predicting organ failure, complications, and mortality in acute pancreatitis
    Georgios I Papachristou
    Division of Gastroenterology, Hepatology and Nutrition, Department of Medicine, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA
    Am J Gastroenterol 105:435-41; quiz 442. 2010
  5. doi request reprint Comparison of existing clinical scoring systems to predict persistent organ failure in patients with acute pancreatitis
    Rawad Mounzer
    Division of Gastroenterology, Hepatology and Nutrition, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA
    Gastroenterology 142:1476-82; quiz e15-6. 2012
  6. pmc Are genetic variants in the platelet-derived growth factor [beta] gene associated with chronic pancreatitis?
    Venkata Muddana
    Division of Gastroenterology, Department of Medicine, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA
    Pancreas 39:1215-9. 2010
  7. doi request reprint SPINK1 N34S is strongly associated with recurrent acute pancreatitis but is not a risk factor for the first or sentinel acute pancreatitis event
    Elie Aoun
    Division of Gastroenterology, Hepatology and Nutrition, Department of Medicine, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA
    Am J Gastroenterol 105:446-51. 2010
  8. pmc Pathways to injury in chronic pancreatitis: decoding the role of the high-risk SPINK1 N34S haplotype using meta-analysis
    Elie Aoun
    Division of Gastroenterology, Hepatology and Nutrition, Department of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America
    PLoS ONE 3:e2003. 2008
  9. pmc TNF-alpha gene (TNFA) variants increase risk for multi-organ dysfunction syndrome (MODS) in acute pancreatitis
    Faraz Bishehsari
    Department of Medicine, University of Pittsburgh and University of Pittsburgh Medical Center, Pittsburgh, PA, USA
    Pancreatology 12:113-8. 2012
  10. ncbi request reprint The MCP-1 -2518 A/G polymorphism is not a susceptibility factor for chronic pancreatitis
    David A Sass
    Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA
    Pancreatology 6:297-300. 2006

Detail Information

Publications61

  1. doi request reprint Low serum adiponectin levels are associated with systemic organ failure in acute pancreatitis
    Arun Sharma
    Division of Gastroenterology, Hepatology and Nutrition, Department of Medicine, University of Pittsburgh, Pittsburgh, PA 15213, USA
    Pancreas 38:907-12. 2009
    ..We tested the hypothesis that serum adiponectin, the primary anti-inflammatory adipokine, is associated with functional polymorphisms in the adiponectin gene (ADIPOQ) and inversely associated with SAP...
  2. ncbi request reprint Pharmacological therapy for acute pancreatitis: where are we now? where are we going?
    J J Easler
    University of Pittsburgh Medical Center, Pittsburgh, PA, USA
    Minerva Gastroenterol Dietol 58:365-76. 2012
    ..A few of these therapies have demonstrated promise in significantly altering the progression of this disease. Further studies are needed to clearly elucidate these benefits in patients at risk for poor outcomes...
  3. doi request reprint Epidermal growth factor serum levels and the 61 G/A polymorphism in patients with acute pancreatitis
    Georgios I Papachristou
    Department of Medicine, Division of Gastroenterology, Hepatology and Nutrition, University of Pittsburgh Medical Center, Presbyterian, M2 C Wing, 200 Lothrop Street, Pittsburgh, PA 15213, USA
    Dig Dis Sci 55:2676-80. 2010
    ..In animal models, EGF protects against pancreatic injury and prevents septic complications. The role of EGF in human AP is unknown...
  4. doi request reprint Comparison of BISAP, Ranson's, APACHE-II, and CTSI scores in predicting organ failure, complications, and mortality in acute pancreatitis
    Georgios I Papachristou
    Division of Gastroenterology, Hepatology and Nutrition, Department of Medicine, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA
    Am J Gastroenterol 105:435-41; quiz 442. 2010
    ....
  5. doi request reprint Comparison of existing clinical scoring systems to predict persistent organ failure in patients with acute pancreatitis
    Rawad Mounzer
    Division of Gastroenterology, Hepatology and Nutrition, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA
    Gastroenterology 142:1476-82; quiz e15-6. 2012
    ..We head-to-head compared the accuracy of these systems in predicting persistent organ failure, developed rules that combined these scores to optimize predictive accuracy, and validated our findings in an independent cohort...
  6. pmc Are genetic variants in the platelet-derived growth factor [beta] gene associated with chronic pancreatitis?
    Venkata Muddana
    Division of Gastroenterology, Department of Medicine, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA
    Pancreas 39:1215-9. 2010
    ..We also tested the hypothesis that PDGF-[beta] polymorphisms in combination with environmental risk factors such as alcohol and smoking are associated with CP...
  7. doi request reprint SPINK1 N34S is strongly associated with recurrent acute pancreatitis but is not a risk factor for the first or sentinel acute pancreatitis event
    Elie Aoun
    Division of Gastroenterology, Hepatology and Nutrition, Department of Medicine, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA
    Am J Gastroenterol 105:446-51. 2010
    ..Our aim was to study the prevalence of the SPINK1 N34S polymorphism in patients with sentinel and recurrent AP (RAP)...
  8. pmc Pathways to injury in chronic pancreatitis: decoding the role of the high-risk SPINK1 N34S haplotype using meta-analysis
    Elie Aoun
    Division of Gastroenterology, Hepatology and Nutrition, Department of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America
    PLoS ONE 3:e2003. 2008
    ..We tested this hypothesis by evaluating the differences in effect size of the high risk SPINK1 N34S haplotype on CP from multiple etiologies after combining clinical reports of SPINK1 N34S frequency using meta-analysis...
  9. pmc TNF-alpha gene (TNFA) variants increase risk for multi-organ dysfunction syndrome (MODS) in acute pancreatitis
    Faraz Bishehsari
    Department of Medicine, University of Pittsburgh and University of Pittsburgh Medical Center, Pittsburgh, PA, USA
    Pancreatology 12:113-8. 2012
    ..Small genetic cohort studies of the TNFA promoter in AP produced ambiguous results. We performed a comprehensive evaluation of TNFA promoter variants to assess both susceptibility to AP and risk of progression to MODS...
  10. ncbi request reprint The MCP-1 -2518 A/G polymorphism is not a susceptibility factor for chronic pancreatitis
    David A Sass
    Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA
    Pancreatology 6:297-300. 2006
    ..Genetic factors influence susceptibility and modify progression. The monocyte chemotactic protein-1 (MCP-1) -2518 G allele, which modifies the severity of acute pancreatitis, was investigated as a susceptibility factor for CP...
  11. doi request reprint Admission Hematocrit and Rise in Blood Urea Nitrogen at 24 h Outperform other Laboratory Markers in Predicting Persistent Organ Failure and Pancreatic Necrosis in Acute Pancreatitis: A Post Hoc Analysis of Three Large Prospective Databases
    Efstratios Koutroumpakis
    Division of Gastroenterology, Hepatology and Nutrition, Department of Medicine, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA
    Am J Gastroenterol 110:1707-16. 2015
    ....
  12. ncbi request reprint Risk and markers of severe acute pancreatitis
    Georgios I Papachristou
    Division of Gastroenterology, Hepatology and Nutrition, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA
    Gastroenterol Clin North Am 36:277-96, viii. 2007
    ....
  13. doi request reprint Current management and novel insights in acute pancreatitis
    Venkata Muddana
    Department of Medicine, Division of Gastroenterology, Hepatology and Nutrition, University of Pittsburgh Medical Center, PA 15219, USA
    Expert Rev Gastroenterol Hepatol 3:435-44. 2009
    ..The lack of scientific advancements in the management of AP reflects the limited understanding of the early pathogenetic mechanisms and our moderate-to-poor ability to predict severe course at the time of admission...
  14. ncbi request reprint Obesity increases the severity of acute pancreatitis: performance of APACHE-O score and correlation with the inflammatory response
    Georgios I Papachristou
    Division of Gastroenterology, Hepatology and Nutrition, Department of Medicine, University of Pittsburgh, Pittsburgh, PA, USA
    Pancreatology 6:279-85. 2006
    ..Obese patients appear to be at risk for complications of acute pancreatitis (AP). APACHE-O score has been suggested to improve APACHE-II accuracy in predicting severe outcome in AP...
  15. ncbi request reprint Functional polymorphisms of the GSTT-1 gene do not predict the severity of acute pancreatitis in the United States
    Yasser M Bhat
    Division of Gastroenterology, Hepatology, and Nutrition, Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA
    Pancreatology 7:180-6. 2007
    ..Our aim was to determine whether the same GSTT-1 polymorphism affects the severity of AP in a population from Pittsburgh, Pa., USA...
  16. pmc Isolated Peripancreatic Necrosis in Acute Pancreatitis Is Infrequent and Leads to Severe Clinical Course Only When Extensive: A Prospective Study From a US Tertiary Center
    Efstratios Koutroumpakis
    Departments of Medicine, Division of Gastroenterology, Hepatology and Nutrition Radiology, Division of Abdominal Imaging Surgery, Division of Surgical Oncology, University of Pittsburgh Medical Center Department of Medicine, Division of Gastroenterology and Hepatology, Veterans Affairs Pittsburgh Health System, Pittsburgh, PA
    J Clin Gastroenterol 50:589-95. 2016
    ..To explore the diagnostic challenges, management, and clinical outcomes of patients with isolated peripancreatic necrosis (PPN), with emphasis on the extent of involvement, and compare them to pancreatic necrosis (PN)...
  17. doi request reprint Revised Atlanta and determinant-based classification: application in a prospective cohort of acute pancreatitis patients
    Haq Nawaz
    Division of Gastroenterology, Hepatology and Nutrition, Department of Medicine, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA
    Am J Gastroenterol 108:1911-7. 2013
    ....
  18. doi request reprint Angiopoietin-2, a regulator of vascular permeability in inflammation, is associated with persistent organ failure in patients with acute pancreatitis from the United States and Germany
    David C Whitcomb
    Department of Medicine, University of Pittsburgh Medical Center, Pennsylvania, USA
    Am J Gastroenterol 105:2287-92. 2010
    ..The aim of this study was to determine whether Ang-1 and/or Ang-2 levels are predictive biomarkers of persistent organ failure (>48 h) and prolonged hospital course...
  19. doi request reprint Elevated serum creatinine as a marker of pancreatic necrosis in acute pancreatitis
    Venkata Muddana
    Division of Gastroenterology, Hepatology and Nutrition, Department of Medicine, UPMC Presbyterian Hospital, University of Pittsburgh School of Medicine, 200 Lothrop Street, Pittsburgh, PA 15213, USA
    Am J Gastroenterol 104:164-70. 2009
    ..This study focuses on the association between routine laboratory tests and the development of pancreatic necrosis in patients with acute pancreatitis...
  20. ncbi request reprint Rapid evolution from the first episode of acute pancreatitis to chronic pancreatitis in human subjects
    Elie Aoun
    Division of Gastroenterology, Hepatology and Nutrition, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA
    JOP 8:573-8. 2007
    ..The sentinel acute pancreatitis event hypothesis suggests that an initial episode of acute pancreatitis is the first step in a complicated series of events ultimately leading to chronic pancreatitis...
  21. ncbi request reprint Serum proteomic patterns as a predictor of severity in acute pancreatitis
    Georgios I Papachristou
    Division of Gastroenterology, Hepatology and Nutrition, University of Pittsburgh Cancer Institute Hillman Cancer Center, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA
    Pancreatology 7:317-24. 2007
    ....
  22. ncbi request reprint Clinical Profile and Natural Course in a Large Cohort of Patients With Hypertriglyceridemia and Pancreatitis
    Kishore Vipperla
    Department of Medicine, Division of General Internal Medicine Department of Radiology, Division of Abdominal Imaging Department of Medicine, Division of Gastroenterology and Hepatology Department of Biomedical Informatics, University of Pittsburgh Medical Center, Pittsburgh, PA
    J Clin Gastroenterol 51:77-85. 2017
    ..To report the clinical profile and natural course in a large series of patients with hypertriglyceridemia (HTG) and acute pancreatitis (AP)...
  23. doi request reprint Risk of and factors associated with readmission after a sentinel attack of acute pancreatitis
    Kishore Vipperla
    Division of Gastroenterology and Hepatology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania
    Clin Gastroenterol Hepatol 12:1911-9. 2014
    ..We aimed to determine the risk and factors that determine early (within 30 days) and late (after 30 days) readmission of patients with acute pancreatitis...
  24. doi request reprint Natural history following the first attack of acute pancreatitis
    Dhiraj Yadav
    Division of Gastroenterology and Hepatology, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA
    Am J Gastroenterol 107:1096-103. 2012
    ..The objective of this study was to determine the risk of recurrent AP (RAP) and subsequent chronic pancreatitis (CP) diagnosis after the first attack of AP...
  25. ncbi request reprint Is the monocyte chemotactic protein-1 -2518 G allele a risk factor for severe acute pancreatitis?
    Georgios I Papachristou
    Department of Medicine, University of Pittsburgh, Pennsylvania 15213, USA
    Clin Gastroenterol Hepatol 3:475-81. 2005
    ..Our aim was to determine whether the MCP-1 -2518 A/G polymorphism affects the severity of AP...
  26. doi request reprint Blood urea nitrogen in the early assessment of acute pancreatitis: an international validation study
    Bechien U Wu
    Center for Pancreatic Disease, Division of Gastroenterology, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA
    Arch Intern Med 171:669-76. 2011
    ..Herein we (1) validate serial blood urea nitrogen (BUN) measurement for early prediction of mortality and (2) develop an objective BUN-based approach to early assessment in AP...
  27. doi request reprint Diagnostic accuracy of interleukin-6 and interleukin-8 in predicting severe acute pancreatitis: a meta-analysis
    Elie Aoun
    Department of Medicine, Division of Gastroenterology, Hepatology and Nutrition, University of Pittsburgh Medical Center, Pittsburgh, PA, USA
    Pancreatology 9:777-85. 2009
    ..We conducted a meta-analysis to assess the accuracy of IL-6 and IL-8 at predicting SAP...
  28. doi request reprint Endoscopic sphincterotomy (ES) may not alter the natural history of idiopathic recurrent acute pancreatitis (IRAP)
    Rohit Das
    Division of Gastroenterology, Hepatology and Nutrition, University of Pittsburgh Medical Center, Pittsburgh, PA, USA
    Pancreatology 16:770-7. 2016
    ..The role of endoscopic sphincterotomy (ES) in idiopathic recurrent acute pancreatitis (IRAP) is unclear. We hypothesized that ES will alter the natural history of IRAP...
  29. pmc Patients With Sentinel Acute Pancreatitis of Alcoholic Etiology Are at Risk for Organ Failure and Pancreatic Necrosis: A Dual-Center Experience
    Jeffrey J Easler
    From the Division of Gastroenterology, Hepatology and Nutrition, University of Pittsburgh Medical Center, Pittsburgh, PA Department of Gastroenterology, Hospital General Universitario de Alicante, Instituto de Investigación Sanitaria y Biomédica de Alicante ISABIAL Fundación FISABIO, Alicante, Spain and Department of Gastroenterology and Hepatology, Mayo Clinic, Scottsdale, AZ
    Pancreas 45:997-1002. 2016
    ..To assess the relationship between alcoholic etiology, tobacco use, and severe acute pancreatitis (AP)...
  30. doi request reprint Elevated serum triglycerides are independently associated with persistent organ failure in acute pancreatitis
    Haq Nawaz
    Department of Medicine, Division of Gastroenterology, Hepatology and Nutrition, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA
    Am J Gastroenterol 110:1497-503. 2015
    ..Hypertriglyceridemia (HTG) represents a major health problem with prevalence exceeding 30% in the U.S. The present study aims to assess the effect of elevated serum triglyceride (TG) levels on the severity of acute pancreatitis (AP)...
  31. pmc Performance characteristics of endoscopic ultrasound in the staging of pancreatic cancer: a meta-analysis
    Haq Nawaz
    Division of Gastroenterology, Hepatology and Nutrition, University of Pittsburgh Medical Center Pittsburgh, PA, USA
    JOP 14:484-97. 2013
    ..The optimal approach to pre-operative imaging assessment of pancreatic cancer is unknown...
  32. pmc Endoscopic therapy is effective for patients with chronic pancreatitis
    Bridger Clarke
    Department of Medicine, University of Pittsburgh, Pittsburgh, PA 15213, USA
    Clin Gastroenterol Hepatol 10:795-802. 2012
    ..We evaluated use and long-term effectiveness of ET in a well-defined cohort of patients with CP...
  33. ncbi request reprint Inflammatory markers of disease severity in acute pancreatitis
    Georgios I Papachristou
    Division of Gastroenterology, Hepatology and Nutrition, Department of Medicine, University of Pittsburgh, 200 Lothrop Street, Pittsburgh, PA 15213, USA
    Clin Lab Med 25:17-37. 2005
    ..Novel conceptions and approaches, such as identification of genetic polymorphisms that predispose to severe course and complications of AP, are needed for a quantum step forward...
  34. doi request reprint American Gastroenterological Association guidelines are inaccurate in detecting pancreatic cysts with advanced neoplasia: a clinicopathologic study of 225 patients with supporting molecular data
    Aatur D Singhi
    Department of Pathology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA
    Gastrointest Endosc 83:1107-1117.e2. 2016
    ..The aims of this study were to assess the accuracy of the AGA guidelines in detecting advanced neoplasia and present an alternative approach to pancreatic cysts...
  35. ncbi request reprint Natural History After Acute Necrotizing Pancreatitis: a Large US Tertiary Care Experience
    Chandraprakash Umapathy
    Division of General Internal Medicine, University of Pittsburgh, Pittsburgh, PA, USA
    J Gastrointest Surg 20:1844-1853. 2016
    ..Most studies of acute necrotizing pancreatitis (ANP) focus on short-term outcomes. We evaluated long-term survival and outcomes following ANP...
  36. pmc Angiotensin-converting enzyme gene DD genotype neither increases susceptibility to acute pancreatitis nor influences disease severity
    Nevin Oruc
    Department of Medicine, Division of Gastroenterology, University of Pittsburgh, PA, USA
    HPB (Oxford) 11:45-9. 2009
    ..Objectives were to investigate the occurrence of the ACE insertion/deletion (I/D) polymorphism in acute pancreatitis patients and its association with the severity of the disease...
  37. doi request reprint Endotherapy is effective for pancreatic ductal disruption: A dual center experience
    Rohit Das
    Division of Gastroenterology, Hepatology and Nutrition, University of Pittsburgh Medical Center, Pittsburgh, PA, USA
    Pancreatology 16:278-83. 2016
    ..The aim of this study was to provide an evaluation on the efficacy of endotherapy for treatment of PD disruption in a large cohort of patients and identify factors that predict successful treatment outcome...
  38. doi request reprint Portosplenomesenteric venous thrombosis in patients with acute pancreatitis is associated with pancreatic necrosis and usually has a benign course
    Jeffrey Easler
    Division of Gastroenterology and Hepatology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania
    Clin Gastroenterol Hepatol 12:854-62. 2014
    ..We evaluated the prevalence and natural history of PSMVT in a well-defined cohort of individuals with AP...
  39. pmc Common genetic variants in the CLDN2 and PRSS1-PRSS2 loci alter risk for alcohol-related and sporadic pancreatitis
    David C Whitcomb
    Division of Gastroenterology, Hepatology and Nutrition, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA
    Nat Genet 44:1349-54. 2012
    ..These results could partially explain the high frequency of alcohol-related pancreatitis in men (male hemizygote frequency is 0.26, whereas female homozygote frequency is 0.07)...
  40. ncbi request reprint Predictors of severity and necrosis in acute pancreatitis
    Georgios I Papachristou
    Division of Gastroenterology, Hepatology and Nutrition, Department of Medicine, University of Pittsburgh, 200 Lothrop Street, Pittsburgh, PA 15213, USA
    Gastroenterol Clin North Am 33:871-90. 2004
    ..Novel conceptions and approaches, such as identification of genetic polymorphisms that predispose to severe course and complications of AP or other approaches are needed for a quantum step forward...
  41. ncbi request reprint Alcohol-associated pancreatitis
    Dhiraj Yadav
    Department of Medicine, University of Pittsburgh, Pittsburgh, PA 15213, USA
    Gastroenterol Clin North Am 36:219-38, vii. 2007
    ..Newer developments in the understanding of complex disorders allow clinicians to understand better the role of cofactors and interactions between known and yet unknown environmental and genetic factors in causing alcoholic pancreatitis...
  42. ncbi request reprint Necrotizing pancreatitis
    Steven J Hughes
    Section of Gastrointestinal Surgery, Department of Surgery, University of Pittsburgh School of Medicine, 497 Scaife Hall, 3550 Terrace Street, Pittsburgh, PA 15261, USA
    Gastroenterol Clin North Am 36:313-23, viii. 2007
    ..This article presents a multidisciplinary literature-based approach to the treatment of patients with necrotizing pancreatitis...
  43. ncbi request reprint Chronic alcohol consumption is a major risk factor for pancreatic necrosis in acute pancreatitis
    Georgios I Papachristou
    Department of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
    Am J Gastroenterol 101:2605-10. 2006
    ..Early diagnosis of PNEC in high-risk patients is critical to management. Hemoconcentration is one risk factor for PNEC, but additional risk factors are likely implicated...
  44. doi request reprint Severity and natural history of acute pancreatitis in diabetic patients
    Haq Nawaz
    University of Pittsburgh Medical Center, Pittsburgh, PA, USA
    Pancreatology 15:247-52. 2015
    ..There is limited data on the prevalence of coexistent diabetes in acute pancreatitis and subsequent natural history in these patients...
  45. doi request reprint Cyst Gastrostomy and Necrosectomy for the Management of Sterile Walled-Off Pancreatic Necrosis: a Comparison of Minimally Invasive Surgical and Endoscopic Outcomes at a High-Volume Pancreatic Center
    Mohammad Khreiss
    Department of Surgery, School of Medicine, University of Pittsburgh, Pittsburgh, PA, USA
    J Gastrointest Surg 19:1441-8. 2015
    ..We sought to compare the outcomes of minimally invasive surgical and endoscopic cyst gastrostomy (CG) and necrosectomy for the management for sterile WON at a tertiary care high-volume pancreas center...
  46. ncbi request reprint Endoscopic retrograde cholangiopancreatography tissue sampling: when and how?
    Georgios I Papachristou
    Department of Medicine, Division of Gastroenterology, Hepatology and Nutrition, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA
    Clin Gastroenterol Hepatol 5:783-90. 2007
    ..This case-based educational presentation focuses on the importance of interdisciplinary communication between endoscopists and pathologists for optimal tissue sampling, interpretation, and diagnostic accuracy...
  47. ncbi request reprint Acute deterioration of a woman following acute pancreatitis with pseudocysts
    Elie Aoun
    University of Pittsburgh Medical Center, PA 15213, USA
    Nat Clin Pract Gastroenterol Hepatol 2:545-9; quiz 550. 2005
    ..Initial blood work revealed a drop in her hematocrit, and elevated but stable amylase and lipase levels. A CT scan of the abdomen revealed a splenic artery pseudoaneurysm with extravasation of contrast medium into an adjacent pseudocyst...
  48. doi request reprint Direct endoscopic necrosectomy for the treatment of walled-off pancreatic necrosis: results from a multicenter U.S. series
    Timothy B Gardner
    Section of Gastroenterology and Hepatology, Department of Medicine, Dartmouth Hitchcock Medical Center, Lebanon, New Hampshire, USA
    Gastrointest Endosc 73:718-26. 2011
    ..Direct endoscopic necrosectomy (DEN) for treatment of walled-off pancreatic necrosis (WOPN) has been performed as an alternative to operative or percutaneous therapy...
  49. doi request reprint The role of apheresis in hypertriglyceridemia-induced acute pancreatitis: A systematic review
    Benjamin Click
    Division of Gastroenterology and Hepatology, University of Pittsburgh Medical Center, Pittsburgh, PA, USA
    Pancreatology 15:313-20. 2015
    ..We performed a systematic review of available literature on this topic with specific focus on disease severity...
  50. doi request reprint Pancreaticobiliary complications after composite visceral transplantation: incidence, risk, and management strategies
    Georgios I Papachristou
    Division of Gastroenterology, Department of Medicine, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA
    Gastrointest Endosc 73:1165-73. 2011
    ..Combined liver/small-bowel (L/SB) and multivisceral (MV) transplantation has been increasingly used with significant improvement in outcome...
  51. ncbi request reprint Endoscopic palliation of pancreatic cancer
    Michael Sanders
    Division of Gastroenterology, Hepatology and Nutrition, Department of Medicine, University of Pittsburgh Medical Center, Mezzanine Level, C Wing, UPMC Presbyterian, 200 Lothrop Street, Pittsburgh, PA 15213, USA
    Gastroenterol Clin North Am 36:455-76, xi. 2007
    ....
  52. ncbi request reprint Endoscopist administered sedation during ERCP: impact of chronic narcotic/benzodiazepine use and predictive risk of reversal agent utilization
    Georgios I Papachristou
    Department of Medicine, Division of Gastroenterology and Hepatology, Mayo Clinic College of Medicine, Rochester, Minnesota, USA
    Am J Gastroenterol 102:738-43. 2007
    ....
  53. ncbi request reprint Systemic silicosis that involves the pancreas
    Georgios I Papachristou
    Department of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
    Gastrointest Endosc 63:170-2. 2006
  54. ncbi request reprint Use of stents in benign and malignant esophageal disease
    Georgios I Papachristou
    Department of Medicine, Division of Gastroenterology, Hepatology and Nutrition, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA
    Rev Gastroenterol Disord 7:74-88. 2007
    ..Future developments in stent design include biodegradable stents, stents with a radioactive coating, and drug-eluting stents...
  55. pmc Acute pancreatitis patient registry to examine novel therapies in clinical experience (APPRENTICE): an international, multicenter consortium for the study of acute pancreatitis
    Georgios I Papachristou
    Division of Gastroenterology and Hepatology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA Georgios I Papachristou, Jorge D Machicado, Phil J Greer, Mohannad Dugum, Efstratios Koutroumpakis Amir Gougol
    Ann Gastroenterol 30:106-113. 2017
    ..We have established a multicenter international consortium to better understand the natural history of acute pancreatitis (AP) worldwide and to develop a platform for future randomized clinical trials...
  56. doi request reprint Endoscopic Treatment of Recurrent Acute Pancreatitis and Smoldering Acute Pancreatitis
    Rohit Das
    Division of Gastroenterology, Hepatology and Nutrition, University of Pittsburgh Medical Center, PUH, M2, C Wing, 200 Lothrop Street, Pittsburgh, PA 15213, USA
    Gastrointest Endosc Clin N Am 25:737-48. 2015
    ..This review discusses the literature available on these topic as well as touching on the role of endoscopic therapy in smoldering acute pancreatitis. ..
  57. pmc Acute lipotoxicity regulates severity of biliary acute pancreatitis without affecting its initiation
    Chandra Durgampudi
    Department of Medicine, University of Pittsburgh Medical Center Pasavant, Pittsburgh, Pennsylvania
    Am J Pathol 184:1773-84. 2014
    ..Inhibition of lipolysis reduces UFA generation and improves these outcomes of AP without interfering with its induction. ..
  58. doi request reprint An update on minimally invasive therapies for pancreatic necrosis
    Jeffrey J Easler
    Division of Gastroenterology, Hepatology and Nutrition, Pittsburgh, PA, USA
    Expert Rev Gastroenterol Hepatol 6:745-53. 2012
    ..However, additional well-designed, randomized trials are needed...
  59. ncbi request reprint EUS features of annular pancreas (with video)
    Georgios I Papachristou
    Division of Gastroenterology and Hepatology, Department of Medicine, Mayo Clinic College of Medicine, Rochester, Minnesota 55905, USA
    Gastrointest Endosc 65:340-4. 2007
    ..An annular pancreas is a rare congenital anomaly that results in a band of pancreatic tissue, either partially or completely encircling the duodenum...
  60. pmc Expression of integrin-linked kinase and its binding partners in chondrosarcoma: association with prognostic significance
    Dionysios J Papachristou
    Department of Pathology, University of Pittsburgh Medical Center, Pittsburgh, PA, USA
    Eur J Cancer 44:2518-25. 2008
    ..Moreover, our findings highlight the possibilities that ILK might serve as biological marker that could accurately predict a high-grade tumour and that Mig-2 may function as a promising prognostic indicator of high-risk patients...