- High throughput screening for small-molecule inhibitors of type III secretion in Yersinia pestisNing Pan
Department of Molecular Genetics and Microbiology, University of Massachusetts Medical School, USA
Adv Exp Med Biol 603:367-75. 2007..They are a diverse group, each having chemical scaffolds not only distinct from one another, but also distinct from previously described candidate T3S inhibitors...
- Evaluation of the role of LcrV-Toll-like receptor 2-mediated immunomodulation in the virulence of Yersinia pestisKimberly Pouliot
Department of Molecular Genetics and Microbiology, University of Massachusetts Medical School, 55 Lake Avenue North, Worcester, MA 01655, USA
Infect Immun 75:3571-80. 2007..Taken together, our data indicate that the most abundant molecular species of Y. pestis LcrV do not efficiently activate TLR2-signaling and that TLR2-mediated immunomodulation is unlikely to play a significant role in plague...