Affiliation: University of California
- Molecular and cellular mechanisms of the age-dependency of opioid analgesia and toleranceJing Zhao
Department of Anesthesia, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100730, China
Mol Pain 8:38. 2012....
- Age-dependent opioid escalation in chronic pain patientsChante Buntin-Mushock
University of California, San Francisco, Department of Anesthesia and Perioperative Care, 513 Parnassus Ave, Box 0464, Room S 455, San Francisco, CA 94143, USA
Anesth Analg 100:1740-5. 2005..Although factors other than opioid tolerance can result in dose escalation, it is possible that older patients may have a reduced rate of tolerance development...
- Age-dependent morphine tolerance development in the ratYan Wang
Department of Anesthesia and Perioperative Care, University of California, San Francisco, 513 Parnassus Ave, Box 0464, Room S 455, San Francisco, CA 94143, USA
Anesth Analg 100:1733-9. 2005..Aging may impact molecular processes involved in tolerance development and provide insight into novel therapeutic targets to delay opioid tolerance development...
- Differential expression of the regulator of G protein signaling RGS9 protein in nociceptive pathways of different age ratsKi Jun Kim
University of California, San Francisco, Department of Anesthesia and Perioperative Care, 513 Parnassus Avenue, Box 0464, Room S 455, San Francisco, CA 94143, USA
Brain Res Dev Brain Res 160:28-39. 2005..Such differential expression may play an important role in neuronal differentiation and development as well as in neuronal function, such as dopamine and opioid signaling...
- RGS proteins: new players in the field of opioid signaling and tolerance mechanismsGuo Xi Xie
Department of Anesthesia and Perioperative Care, University of California, San Francisco, 513 Parnassus Avenue, Box 0464, Room S 455, San Francisco, CA 94143, USA
Anesth Analg 100:1034-42. 2005..Using RGS proteins as targets for future drug therapy aimed at modulating opioid effectiveness in both acute and chronic pain settings may be an important advance in the treatment of pain...
- Mu-opioid receptor mRNA regulation during morphine tolerance in the rat peripheral nervous systemThomas Meuser
Department of Anesthesiology, University of Cologne, Cologne, Germany
Anesth Analg 97:1458-63. 2003..These data suggest that the peripheral nervous system may be an important site of opioid tolerance development...
- Role of nociceptin in the modulation of nociception in the arcuate nucleus of ratsNing Li
Laboratory of Neurobiology, College of Life Sciences, Peking University, Beijing 100871, P R China
Brain Res 1025:67-74. 2004..The present study also demonstrates an interaction between nociceptin and opioids in the arcuate nucleus of the hypothalamus...
- Preoperative greater occipital nerve block in total thyroidectomy patients can reduce postoperative occipital headache and posterior neck painDong Woo Han
Department of Anesthesiology and Pain Medicine, Anesthesia and Pain Research Institute, Yonsei University College of Medicine, Seoul, Korea
Thyroid 16:599-603. 2006..001). No side effects were observed during and after GON block. We conclude that preoperative GON block with 0.25% bupivacaine is an effective technique to reduce occipital headache and posterior neck pain after thyroid surgery...
- NOCICEPTIN & ORL1 RECEPTOR IN SYNOVIAL INFLAMMATION/PAINPAMELA PALMER; Fiscal Year: 2003..Recently, ORL1 receptor antagonists have been developed and these agents will be used to determine the significance of endogenous nociceptin in chronic synovial inflammation and hyperalgesia. ..
- Transcription regulation & interaction of ORL1 and GAIPPAMELA PALMER; Fiscal Year: 2007..unreadable] [unreadable]..