Frank G Ondrey

Summary

Affiliation: University of Minnesota
Country: USA

Publications

  1. pmc Exons 19 and 21 of epidermal growth factor receptor are highly conserved in squamous cell cancer of the head and neck
    Matthew Carlson
    Department of Otolaryngology, University of Minnesota, MMC 396, 420 Delaware St SE, Minneapolis, MN 55455, USA
    Int J Otolaryngol 2009:649615. 2009
  2. ncbi request reprint Sensorineural hearing loss in Vogt-Koyanagi-Harada syndrome
    Frank G Ondrey
    Department of Otolaryngology, University of Minnesota, Minneapolis, Minnesota, USA
    Laryngoscope 116:1873-6. 2006
  3. doi request reprint Peroxisome proliferator-activated receptor gamma pathway targeting in carcinogenesis: implications for chemoprevention
    Frank Ondrey
    Department of Otolaryngology and University of Minnesota Masonic Cancer Center, University of Minnesota, Minneapolis, Minnesota 55455, USA
    Clin Cancer Res 15:2-8. 2009
  4. pmc Inhibitor of differentiation 1 contributes to head and neck squamous cell carcinoma survival via the NF-kappaB/survivin and phosphoinositide 3-kinase/Akt signaling pathways
    Jizhen Lin
    Department of Otolaryngology, Cancer Center, University of Minnesota, Minneapolis, Minnesota 55455, USA
    Clin Cancer Res 16:77-87. 2010
  5. ncbi request reprint Inositol hexaphosphate and paclitaxel: symbiotic treatment of oral cavity squamous cell carcinoma
    Seth C Janus
    Department of Otolaryngology, University of Minnesota, Minneapolis, Minnesota 55455, USA
    Laryngoscope 117:1381-8. 2007
  6. doi request reprint Ototoxicity after combined platinum and fractionated radiation in a novel guinea pig model
    Matthew W Miller
    Otolaryngology Department, University of Minnesota, Minneapolis, MN, USA
    Am J Otolaryngol 30:1-7. 2009
  7. pmc Expression of fibroblast growth factor binding protein in head and neck cancer
    Weimin Li
    Department of Otolaryngology, University of Minnesota School of Medicine, Minneapolis, MN 55455, USA
    Arch Otolaryngol Head Neck Surg 135:896-901. 2009
  8. doi request reprint The effect of indomethacin on paclitaxel sensitivity and apoptosis in oral squamous carcinoma cells: the role of nuclear factor-κB inhibition
    Emiro E Caicedo-Granados
    Molecular Oncology Program, Department of Otolaryngology, University of Minnesota, Minneapolis, MN 55455, USA
    Arch Otolaryngol Head Neck Surg 137:799-805. 2011
  9. pmc Pneumococcal peptidoglycan-polysaccharides induce the expression of interleukin-8 in airway epithelial cells by way of nuclear factor-kappaB, nuclear factor interleukin-6, or activation protein-1 dependent mechanisms
    Katsuyuki Tsuchiya
    Department of Otolaryngology, University of Minnesota Otitis Media Research Center, University of Minnesota School of Medicine, Minneapolis, Minnesota, USA
    Laryngoscope 117:86-91. 2007
  10. doi request reprint Enforced expression of nuclear factor kappa B in p53 deficient keratinocytes induces cell cycle, angiogenic potential and tumorigenesis
    Emiro E Caicedo-Granados
    Department of Otolaryngology, University of Minnesota, Minneapolis, MN, USA
    Oral Oncol 48:303-10. 2012

Collaborators

Detail Information

Publications27

  1. pmc Exons 19 and 21 of epidermal growth factor receptor are highly conserved in squamous cell cancer of the head and neck
    Matthew Carlson
    Department of Otolaryngology, University of Minnesota, MMC 396, 420 Delaware St SE, Minneapolis, MN 55455, USA
    Int J Otolaryngol 2009:649615. 2009
    ....
  2. ncbi request reprint Sensorineural hearing loss in Vogt-Koyanagi-Harada syndrome
    Frank G Ondrey
    Department of Otolaryngology, University of Minnesota, Minneapolis, Minnesota, USA
    Laryngoscope 116:1873-6. 2006
    ....
  3. doi request reprint Peroxisome proliferator-activated receptor gamma pathway targeting in carcinogenesis: implications for chemoprevention
    Frank Ondrey
    Department of Otolaryngology and University of Minnesota Masonic Cancer Center, University of Minnesota, Minneapolis, Minnesota 55455, USA
    Clin Cancer Res 15:2-8. 2009
    ..This article will review translational findings in PPARgamma activation and targeting in carcinogenesis prevention as they relate to the potential use of PPARgamma activators clinically as cancer chemoprevention strategies...
  4. pmc Inhibitor of differentiation 1 contributes to head and neck squamous cell carcinoma survival via the NF-kappaB/survivin and phosphoinositide 3-kinase/Akt signaling pathways
    Jizhen Lin
    Department of Otolaryngology, Cancer Center, University of Minnesota, Minneapolis, Minnesota 55455, USA
    Clin Cancer Res 16:77-87. 2010
    ..A key issue in cancer is apoptosis resistance. However, little is known about the transcription factors that contribute to cellular survival of head and neck squamous cell carcinoma (HNSCC)...
  5. ncbi request reprint Inositol hexaphosphate and paclitaxel: symbiotic treatment of oral cavity squamous cell carcinoma
    Seth C Janus
    Department of Otolaryngology, University of Minnesota, Minneapolis, Minnesota 55455, USA
    Laryngoscope 117:1381-8. 2007
    ..Resulting levels of cell death and apoptosis were assessed, and conclusions are drawn regarding a possible synergistic relationship between paclitaxel and IP6...
  6. doi request reprint Ototoxicity after combined platinum and fractionated radiation in a novel guinea pig model
    Matthew W Miller
    Otolaryngology Department, University of Minnesota, Minneapolis, MN, USA
    Am J Otolaryngol 30:1-7. 2009
    ..Currently, no ototoxicity studies have been performed in animals receiving similar schedules of radiation or cis-platinum to those patients with head and neck cancer...
  7. pmc Expression of fibroblast growth factor binding protein in head and neck cancer
    Weimin Li
    Department of Otolaryngology, University of Minnesota School of Medicine, Minneapolis, MN 55455, USA
    Arch Otolaryngol Head Neck Surg 135:896-901. 2009
    ..To characterize the expression of fibroblast growth factor binding protein (FGF-BP) messenger RNA (mRNA) in head and neck squamous cell carcinoma (HNSCC) and to study the association of FGF-BP with vascularity...
  8. doi request reprint The effect of indomethacin on paclitaxel sensitivity and apoptosis in oral squamous carcinoma cells: the role of nuclear factor-κB inhibition
    Emiro E Caicedo-Granados
    Molecular Oncology Program, Department of Otolaryngology, University of Minnesota, Minneapolis, MN 55455, USA
    Arch Otolaryngol Head Neck Surg 137:799-805. 2011
    ..To investigate new strategies to intensify chemosensitivity in head and neck squamous cell carcinoma...
  9. pmc Pneumococcal peptidoglycan-polysaccharides induce the expression of interleukin-8 in airway epithelial cells by way of nuclear factor-kappaB, nuclear factor interleukin-6, or activation protein-1 dependent mechanisms
    Katsuyuki Tsuchiya
    Department of Otolaryngology, University of Minnesota Otitis Media Research Center, University of Minnesota School of Medicine, Minneapolis, Minnesota, USA
    Laryngoscope 117:86-91. 2007
    ..In a similar way, lipopolysaccharides induced the promoter activation of IL-8 in NL-20. However, the PGPS-induced IL-8 promoter activation in rodent middle ear epithelial cells required NF-kappaB and NF-IL6 but not AP-1...
  10. doi request reprint Enforced expression of nuclear factor kappa B in p53 deficient keratinocytes induces cell cycle, angiogenic potential and tumorigenesis
    Emiro E Caicedo-Granados
    Department of Otolaryngology, University of Minnesota, Minneapolis, MN, USA
    Oral Oncol 48:303-10. 2012
    ....
  11. ncbi request reprint Id1 induces the proliferation of cochlear sensory epithelial cells via the nuclear factor-kappaB/cyclin D1 pathway in vitro
    Masashi Ozeki
    Auditory Molecular Biology Laboratory, Department of Otolaryngology University of Minnesota, Minneapolis, Minnesota, USA
    J Neurosci Res 85:515-24. 2007
    ..We concluded from this study that Id1 induces the proliferation of OC1 via the NF-kappaB/cyclin D1 pathway...
  12. ncbi request reprint Induction of heat shock protein 70 inhibits NF-kappa-B in squamous cell carcinoma
    Timothy A King
    Department of Otorhinolaryngology Head and Neck Surgery, University of Minnesota, Minneapolis 55455, USA
    Otolaryngol Head Neck Surg 133:70-9. 2005
    ..To determine the relationship between heat shock proteins (HSPs) and the proinflammatory, anti-apoptosis mediator NF-kappa-B in squamous cell carcinoma...
  13. ncbi request reprint A method of producing carcinoma in upper aerodigestive tree and esophagus of the Syrian golden hamster using wounding and instillation of N-methylnitrosourea
    Richard D Estensen
    Department of Laboratory Medicine and Pathology, University of Minnesota School of Medicine, Minneapolis, Minnesota USA
    Cancer Epidemiol Biomarkers Prev 16:1644-50. 2007
    ..These tumors of digestive epithelium have a growth pattern that differs from that of the respiratory epithelium in that they grow and invade without filling the epithelial layer with tumor cells...
  14. doi request reprint Functional activation of PPARγ in human upper aerodigestive cancer cell lines
    Simon K Wright
    Department of Otolaryngology, University of Minnesota, Minneapolis, Minnesota
    Mol Carcinog . 2016
    ..PPARγ expression in human upper aerodigestive tract tumors and normal cells potentially legitimizes it as a novel intervention target in this disease. © 2016 Wiley Periodicals, Inc...
  15. ncbi request reprint Efficacy of an osmotic pump delivered, GM-CSF-based tumor vaccine in the treatment of upper aerodigestive squamous cell carcinoma in rats
    Hamid R Djalilian
    Department of Otolaryngology, University of Minnesota, Minneapolis, MN 55455, USA
    Cancer Immunol Immunother 56:1207-14. 2007
    ..We presently tested the efficacy of granulocyte macrophage-colony stimulating factor (GM-CSF) delivered via 28-day continuous infusion pump, in combination with irradiated tumor cells, in a flank model of UADT cancer...
  16. ncbi request reprint Genes associated with early development, apoptosis and cell cycle regulation define a gene expression profile of adenoid cystic carcinoma
    Ketan J Patel
    Division of Hematology, Oncology and Transplantation, Department of Medicine, University of Minnesota School of Medicine, MMC 480, 420 Delaware Street SE, Minneapolis, MN 55455, USA
    Oral Oncol 42:994-1004. 2006
    ..These results demonstrate that ACC tumors express genes associated with early developmental processes including morphogenesis and neurogenesis implicating oncogenic events that result in dedifferentiation of normal salivary glands...
  17. ncbi request reprint A new immune-competent animal model of mucosally derived squamous cell carcinoma
    Hamid R Djalilian
    Department of Otolaryngology, University of Minnesota, Minneapolis, MN, USA
    Otolaryngol Head Neck Surg 131:781-3. 2004
    ..To develop an immune-competent animal model for mucosally derived squamous cell carcinoma (SCCA)...
  18. ncbi request reprint Identification of a gene expression signature associated with recurrent disease in squamous cell carcinoma of the head and neck
    Matthew A Ginos
    Division of Hematology, Oncology and Transplantation, Department of Medicine, University of Minnesota School of Medicine, Minneapolis, Minnesota 55455, USA
    Cancer Res 64:55-63. 2004
    ..These data provide evidence for a new gene expression-based biomarker of local treatment failure in HNSCC...
  19. ncbi request reprint PPAR activation and decreased proliferation in oral carcinoma cells with 4-HPR
    George Harris
    Department of Otolaryngology, University of Minnesota, Minneapolis, Minnesota 55455, USA
    Otolaryngol Head Neck Surg 133:695-701. 2005
    ..Also, to examine whether anti-proliferative effects of this agent in head and neck cancer cells occur at biologically relevant concentrations...
  20. ncbi request reprint Characterization of a temperature-sensitive mouse middle ear epithelial cell line
    Katsuyuki Tsuchiya
    Department of Otolaryngology, Otitis Media Research Center, University of Minnesota School of Medicine, Minneapolis, Minnesota, USA
    Acta Otolaryngol 125:823-9. 2005
    ..Temperature-sensitive mouse middle ear epithelial cells have been successfully established and characterized...
  21. pmc Quantitative proteomics reveals myosin and actin as promising saliva biomarkers for distinguishing pre-malignant and malignant oral lesions
    Ebbing P de Jong
    Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesota, Minneapolis, Minnesota, USA
    PLoS ONE 5:e11148. 2010
    ..A test for proteins, ones found in non-invasively-collected whole saliva and whose abundances distinguish these lesion types, would meet this critical need...
  22. doi request reprint Interleukin-8 production in response to tumor necrosis factor-alpha by cholesteatoma keratinocytes in cell culture
    Christopher W Hilton
    Department of Otolaryngology, University of Minnesota, Minneapolis, Minnesota 55455 0392, USA
    Laryngoscope 121:372-4. 2011
    ..TNF-alpha stimulates IL-8 production in healthy epidermal keratinocyte cell lines. It is not known whether TNF-alpha stimulates IL-8 production in cultured cholesteatoma keratinocytes...
  23. doi request reprint Tobacco carcinogen mediated up-regulation of AP-1 dependent pro-angiogenic cytokines in head and neck carcinogenesis
    Wade G Swenson
    Molecular Oncology Program, Department of Otolaryngology, University of Minnesota, Minneapolis, 55455, USA
    Mol Carcinog 50:668-79. 2011
    ..This up-regulation may promote an angiogenic phenotype favoring invasion in both premalignant and squamous cancer cells of the head and neck...
  24. ncbi request reprint Decreased hearing after combined modality therapy for head and neck cancer
    Susan E Pearson
    Department of Otolaryngology, University of Minnesota, SE, Box 396, Minneapolis, MN 55425, USA
    Am J Otolaryngol 27:76-80. 2006
    ..Combined platinum-based chemoradiation therapy is frequently being used as therapy for head and neck cancer at multiple sites. These therapies are individually ototoxic, but little has been reported on their combined toxicity...
  25. ncbi request reprint Irreversible ototoxicity associated with difluoromethylornithine
    Christopher D Lao
    Department of Internal Medicine, University of Michigan Medical Center, Ann Arbor, 48109, USA
    Cancer Epidemiol Biomarkers Prev 13:1250-2. 2004
    ..This is the first case reported of irreversible ototoxicity in a clinical trial participant receiving DFMO and, thus, trial participants should be made aware of this small but important risk...
  26. doi request reprint Pilot randomized phase II study of celecoxib in oral premalignant lesions
    Vassiliki A Papadimitrakopoulou
    Department of Thoracic Head, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Clin Cancer Res 14:2095-101. 2008
    ..In this pilot randomized phase II study, we evaluated the efficacy and safety of the COX-2 inhibitor celecoxib in patients with oral premalignant lesions (OPL)...
  27. ncbi request reprint A pilot study of longitudinal serum cytokine and angiogenesis factor levels as markers of therapeutic response and survival in patients with head and neck squamous cell carcinoma
    Colleen H Druzgal
    Head and Neck Surgery Branch, National Institute on Deafness and Other Communication Disorders, National Institutes of Health, Bldg 10 CRC, Rm 4 2732, 10 Center Drive, Bethesda, MD 20892, USA
    Head Neck 27:771-84. 2005
    ..Pretreatment and posttreatment serum levels of cytokines and angiogenesis factors were evaluated as markers for outcome in patients with HNSCC...