Igor L Novak

Summary

Affiliation: University of Connecticut Health Center
Country: USA

Publications

  1. pmc Diffusion in cytoplasm: effects of excluded volume due to internal membranes and cytoskeletal structures
    Igor L Novak
    Richard D Berlin Center for Cell Analysis and Modeling, Department of Cell Biology, University of Connecticut Health Center, Farmington, Connecticut, USA
    Biophys J 97:758-67. 2009
  2. pmc Diffusion amid random overlapping obstacles: similarities, invariants, approximations
    Igor L Novak
    Richard D Berlin Center for Cell Analysis and Modeling, Department of Cell Biology, University of Connecticut Health Center, Farmington, Connecticut 06030, USA
    J Chem Phys 134:154104. 2011
  3. pmc An open model of actin dendritic nucleation
    Jonathon A Ditlev
    Richard D Berlin Center for Cell Analysis and Modeling, University of Connecticut Health Center, Farmington, CT 06030 1507, USA
    Biophys J 96:3529-42. 2009
  4. pmc Virtual Cell: computational tools for modeling in cell biology
    Diana C Resasco
    Richard D Berlin Center for Cell Analysis and Modeling, Department of Cell Biology, University of Connecticut Health Center, Farmington, CT, USA
    Wiley Interdiscip Rev Syst Biol Med 4:129-40. 2012
  5. pmc Quantitative analysis of G-actin transport in motile cells
    Igor L Novak
    Center for Cell Analysis and Modeling, University of Connecticut Health Center, Farmington, Connecticut 06030, USA
    Biophys J 95:1627-38. 2008
  6. pmc Actin bundling: initiation mechanisms and kinetics
    Pavel Kraikivski
    Richard D Berlin Center for Cell Analysis and Modeling, Department of Cell Biology, University of Connecticut Health Center, Farmington, CT 06030, USA
    Phys Rev Lett 101:128102. 2008
  7. pmc Numerical Approach to Spatial Deterministic-Stochastic Models Arising in Cell Biology
    James C Schaff
    Richard D Berlin Center for Cell Analysis and Modeling, Department of Cell Biology, University of Connecticut Health Center, Farmington, Connecticut, United States of America
    PLoS Comput Biol 12:e1005236. 2016
  8. ncbi request reprint Cooperativity between cell contractility and adhesion
    Igor L Novak
    Department of Cell Biology, University of Connecticut Health Center, Farmington, Connecticut 06030, USA
    Phys Rev Lett 93:268109. 2004

Collaborators

Detail Information

Publications8

  1. pmc Diffusion in cytoplasm: effects of excluded volume due to internal membranes and cytoskeletal structures
    Igor L Novak
    Richard D Berlin Center for Cell Analysis and Modeling, Department of Cell Biology, University of Connecticut Health Center, Farmington, Connecticut, USA
    Biophys J 97:758-67. 2009
    ..The study lays the foundation for an accurate coarse-grain formulation that would account for cytoplasm heterogeneity on a micron scale and binding of tracers to intracellular structures...
  2. pmc Diffusion amid random overlapping obstacles: similarities, invariants, approximations
    Igor L Novak
    Richard D Berlin Center for Cell Analysis and Modeling, Department of Cell Biology, University of Connecticut Health Center, Farmington, Connecticut 06030, USA
    J Chem Phys 134:154104. 2011
    ..In 3D, the similarities of effective diffusion yield a simple multiplication "rule" that provides a fast means of estimating D(eff) for a mixture of overlapping obstacles of different shapes with comparable sizes...
  3. pmc An open model of actin dendritic nucleation
    Jonathon A Ditlev
    Richard D Berlin Center for Cell Analysis and Modeling, University of Connecticut Health Center, Farmington, CT 06030 1507, USA
    Biophys J 96:3529-42. 2009
    ..Because this model, with the simulation results, is "open source", in the sense that it is publicly available and editable through the Virtual Cell database (http://vcell.org), it can be accessed, analyzed, modified, and extended...
  4. pmc Virtual Cell: computational tools for modeling in cell biology
    Diana C Resasco
    Richard D Berlin Center for Cell Analysis and Modeling, Department of Cell Biology, University of Connecticut Health Center, Farmington, CT, USA
    Wiley Interdiscip Rev Syst Biol Med 4:129-40. 2012
    ..In this article, we review new robust computational tools recently deployed in VCell for treating spatially resolved models...
  5. pmc Quantitative analysis of G-actin transport in motile cells
    Igor L Novak
    Center for Cell Analysis and Modeling, University of Connecticut Health Center, Farmington, Connecticut 06030, USA
    Biophys J 95:1627-38. 2008
    ..We discuss biological implications of the local and global regimes of the G-actin transport...
  6. pmc Actin bundling: initiation mechanisms and kinetics
    Pavel Kraikivski
    Richard D Berlin Center for Cell Analysis and Modeling, Department of Cell Biology, University of Connecticut Health Center, Farmington, CT 06030, USA
    Phys Rev Lett 101:128102. 2008
    ..We propose an experiment for determining which of the two mechanisms is involved in the in vitro bundle formation...
  7. pmc Numerical Approach to Spatial Deterministic-Stochastic Models Arising in Cell Biology
    James C Schaff
    Richard D Berlin Center for Cell Analysis and Modeling, Department of Cell Biology, University of Connecticut Health Center, Farmington, Connecticut, United States of America
    PLoS Comput Biol 12:e1005236. 2016
    ..The solver is then applied to a deterministic-stochastic model of spontaneous emergence of cell polarity. The approach is general enough to be implemented within biologist-friendly software frameworks such as Virtual Cell...
  8. ncbi request reprint Cooperativity between cell contractility and adhesion
    Igor L Novak
    Department of Cell Biology, University of Connecticut Health Center, Farmington, Connecticut 06030, USA
    Phys Rev Lett 93:268109. 2004
    ..The model predicts that the focal adhesions propagate by treadmilling with a velocity proportional to the integrin diffusion coefficient...