Imre Noth

Summary

Affiliation: University of Chicago
Country: USA

Publications

  1. pmc Genetic variants associated with idiopathic pulmonary fibrosis susceptibility and mortality: a genome-wide association study
    Imre Noth
    Section of Pulmonary and Critical Care Medicine, University of Chicago, Chicago, IL, USA Electronic address
    Lancet Respir Med 1:309-17. 2013
  2. pmc A placebo-controlled randomized trial of warfarin in idiopathic pulmonary fibrosis
    Imre Noth
    University of Chicago, 5841 South Maryland Avenue, Chicago, IL 60637 6076, USA
    Am J Respir Crit Care Med 186:88-95. 2012
  3. doi request reprint Prevalence of hiatal hernia by blinded multidetector CT in patients with idiopathic pulmonary fibrosis
    I Noth
    Section of Pulmonary and Critical Care Medicine, University of Chicago, 5841 S Maryland Ave, MC 6076, Chicago, IL 60637, USA
    Eur Respir J 39:344-51. 2012
  4. ncbi request reprint Recent advances in idiopathic pulmonary fibrosis
    Imre Noth
    University of Chicago, Pulmonary and Critical Care, 5841 S Maryland Ave, MC6076, Chicago, IL 60637, USA
    Chest 132:637-50. 2007
  5. pmc A functional genomic model for predicting prognosis in idiopathic pulmonary fibrosis
    Yong Huang
    Section of Pulmonary and Critical Care Medicine, University of Chicago, 5841 S Maryland Avenue, Chicago, IL, 60637 6076, USA
    BMC Pulm Med 15:147. 2015
  6. pmc Autoimmune-featured interstitial lung disease: a distinct entity
    Rekha Vij
    Section of Pulmonary and Critical Care Medicine, Department of Medicine, University of Chicago, 5841 S Maryland Ave, Chicago, IL 60637, USA
    Chest 140:1292-9. 2011
  7. doi request reprint The pulmonary side of reflux disease: from heartburn to lung fibrosis
    Marco E Allaix
    Center for Esophageal Diseases, Department of Surgery, University of Chicago Pritzker School of Medicine, Chicago, IL 60637, USA
    J Gastrointest Surg 17:1526-35. 2013
  8. pmc Pharmacogenetics and interstitial lung disease
    Justin M Oldham
    aDivision of Pulmonary, Critical Care and Sleep Medicine, Department of Internal Medicine, The University of California at Davis, Sacramento, California bDepartment of Medicine, Section of Pulmonary and Critical Care Medicine, The University of Chicago, Chicago, Illinois cDepartment of Internal Medicine, Weill Cornell Medical School, New York City, New York, USA
    Curr Opin Pulm Med 22:456-65. 2016
  9. doi request reprint Idiopathic pulmonary fibrosis and gastroesophageal reflux. Implications for treatment
    Marco E Allaix
    Center for Esophageal Diseases, Department of Surgery, University of Chicago Pritzker School of Medicine, 5841 S Maryland Ave, MC 5031, Room G 207, Chicago, IL, 60637, USA
    J Gastrointest Surg 18:100-4; discussion 104-5. 2014
  10. ncbi request reprint Interstitial lung disease and gastroesophageal reflux disease: key role of esophageal function tests in the diagnosis and treatment
    Renato Vianna Soares
    Department of Surgery, Pritzker School of Medicine, University of Chicago, Chicago, USA
    Arq Gastroenterol 48:91-7. 2011

Collaborators

Detail Information

Publications17

  1. pmc Genetic variants associated with idiopathic pulmonary fibrosis susceptibility and mortality: a genome-wide association study
    Imre Noth
    Section of Pulmonary and Critical Care Medicine, University of Chicago, Chicago, IL, USA Electronic address
    Lancet Respir Med 1:309-17. 2013
    ..Our aim was to identify additional common variants associated with susceptibility and ultimately mortality in IPF...
  2. pmc A placebo-controlled randomized trial of warfarin in idiopathic pulmonary fibrosis
    Imre Noth
    University of Chicago, 5841 South Maryland Avenue, Chicago, IL 60637 6076, USA
    Am J Respir Crit Care Med 186:88-95. 2012
    ..Animal and human studies support the importance of the coagulation cascade in pulmonary fibrosis...
  3. doi request reprint Prevalence of hiatal hernia by blinded multidetector CT in patients with idiopathic pulmonary fibrosis
    I Noth
    Section of Pulmonary and Critical Care Medicine, University of Chicago, 5841 S Maryland Ave, MC 6076, Chicago, IL 60637, USA
    Eur Respir J 39:344-51. 2012
    ..04). HH is more common in IPF than COPD or asthma. In an IPF cohort, HH correlated with higher DeMeester scores, confirming abnormal acid GOR. Presence of HH alone was not associated with decreased lung function...
  4. ncbi request reprint Recent advances in idiopathic pulmonary fibrosis
    Imre Noth
    University of Chicago, Pulmonary and Critical Care, 5841 S Maryland Ave, MC6076, Chicago, IL 60637, USA
    Chest 132:637-50. 2007
    ..The objective of this article is to review advances in the understanding of IPF and the evidence for the findings outlined above...
  5. pmc A functional genomic model for predicting prognosis in idiopathic pulmonary fibrosis
    Yong Huang
    Section of Pulmonary and Critical Care Medicine, University of Chicago, 5841 S Maryland Avenue, Chicago, IL, 60637 6076, USA
    BMC Pulm Med 15:147. 2015
    ..Prognostic models rely on demographic and clinical characteristics and are not reproducible. Integrating data from genomic analyses may identify novel prognostic models and provide mechanistic insights into IPF...
  6. pmc Autoimmune-featured interstitial lung disease: a distinct entity
    Rekha Vij
    Section of Pulmonary and Critical Care Medicine, Department of Medicine, University of Chicago, 5841 S Maryland Ave, Chicago, IL 60637, USA
    Chest 140:1292-9. 2011
    ..We determined the prevalence and characteristics of autoimmune-featured ILD (AIF-ILD) and compared these with those of idiopathic pulmonary fibrosis (IPF) and known connective tissue disease-related ILD (CTD-ILD)...
  7. doi request reprint The pulmonary side of reflux disease: from heartburn to lung fibrosis
    Marco E Allaix
    Center for Esophageal Diseases, Department of Surgery, University of Chicago Pritzker School of Medicine, Chicago, IL 60637, USA
    J Gastrointest Surg 17:1526-35. 2013
    ..Heartburn is the symptom most commonly associated with this disease, and the highly commercialized medical treatment directed toward relief of this symptom represents a 10-billion-dollar-per-year industry...
  8. pmc Pharmacogenetics and interstitial lung disease
    Justin M Oldham
    aDivision of Pulmonary, Critical Care and Sleep Medicine, Department of Internal Medicine, The University of California at Davis, Sacramento, California bDepartment of Medicine, Section of Pulmonary and Critical Care Medicine, The University of Chicago, Chicago, Illinois cDepartment of Internal Medicine, Weill Cornell Medical School, New York City, New York, USA
    Curr Opin Pulm Med 22:456-65. 2016
    ....
  9. doi request reprint Idiopathic pulmonary fibrosis and gastroesophageal reflux. Implications for treatment
    Marco E Allaix
    Center for Esophageal Diseases, Department of Surgery, University of Chicago Pritzker School of Medicine, 5841 S Maryland Ave, MC 5031, Room G 207, Chicago, IL, 60637, USA
    J Gastrointest Surg 18:100-4; discussion 104-5. 2014
    ..Even though the pathogenesis of idiopathic pulmonary fibrosis (IPF) is unknown, there is mounting evidence that abnormal reflux (GERD) and aspiration of gastric contents may play a role in the pathogenesis of this disease...
  10. ncbi request reprint Interstitial lung disease and gastroesophageal reflux disease: key role of esophageal function tests in the diagnosis and treatment
    Renato Vianna Soares
    Department of Surgery, Pritzker School of Medicine, University of Chicago, Chicago, USA
    Arq Gastroenterol 48:91-7. 2011
    ..There is still confusion about the diagnostic steps necessary to confirm the presence of GERD, and about the role of effective control of GERD in the natural history of these respiratory disorders...
  11. pmc Peripheral blood biomarkers in idiopathic pulmonary fibrosis
    Rekha Vij
    Section of Pulmonary and Critical Care Medicine, Department of Medicine, University of Chicago, 5841 S Maryland Ave, Chicago, IL 60637, USA
    Transl Res 159:218-27. 2012
    ..Although there are no validated biomarkers that are currently available, the need for surrogates of diagnosis, prognosis, and monitoring of disease course with emerging therapies is great...
  12. pmc Skewed Lung CCR4 to CCR6 CD4+ T Cell Ratio in Idiopathic Pulmonary Fibrosis Is Associated with Pulmonary Function
    Ayodeji Adegunsoye
    Section of Pulmonary and Critical Care, Department of Medicine, University of Chicago, Chicago, IL, USA
    Front Immunol 7:516. 2016
    ..While it has been suggested that T cells may contribute to IPF pathogenesis, these studies have focused primarily on T cells outside of the pulmonary interstitium. Thus, the role of T cells in the diseased lung tissue remains unclear...
  13. doi request reprint Sphingosine-1-phosphate lyase is an endogenous suppressor of pulmonary fibrosis: role of S1P signalling and autophagy
    Long Shuang Huang
    Department of Pharmacology, The University of Illinois, Chicago, Illinois, USA
    Thorax 70:1138-48. 2015
    ..Idiopathic pulmonary fibrosis (IPF) is characterised by accumulation of fibroblasts and myofibroblasts and deposition of extracellular matrix proteins. Sphingosine-1-phosphate (S1P) signalling plays a critical role in pulmonary fibrosis...
  14. pmc Targeting sphingosine kinase 1 attenuates bleomycin-induced pulmonary fibrosis
    Long Shuang Huang
    Department of Pharmacology, University of Illinois, Chicago, Illinois 60612 7343, USA
    FASEB J 27:1749-60. 2013
    ..Taken together, these data indicate that SphK1 plays a critical role in the pathology of lung fibrosis and is a novel therapeutic target...
  15. pmc Peripheral blood gene expression as a novel genomic biomarker in complicated sarcoidosis
    Tong Zhou
    Institute for Personalized Respiratory Medicine, The University of Illinois at Chicago, Chicago, Illinois, United States of America
    PLoS ONE 7:e44818. 2012
    ..In summary, this validated peripheral blood molecular gene signature appears to be a valuable biomarker in identifying cases with sarcoidoisis and predicting risk for complicated sarcoidosis...
  16. ncbi request reprint Effects of interferon-gamma 1b on biomarker expression in patients with idiopathic pulmonary fibrosis
    Robert M Strieter
    David Geffen School of Medicine at the University of California Los Angeles, Los Angeles, CA 90024 1922, USA
    Am J Respir Crit Care Med 170:133-40. 2004
    ..Changes in biomarkers of fibrosis, angiogenesis, proliferation, immunomodulation, and antimicrobial activity suggest that IFN-gamma 1b may affect IPF through multiple pathways...
  17. pmc Acute exacerbations of idiopathic pulmonary fibrosis
    Harold R Collard
    Department of Medicine, San Francisco General Hospital, University of California, USA
    Am J Respir Crit Care Med 176:636-43. 2007
    ..The potential pathobiological roles of infection, disordered cell biology, coagulation, and genetics are discussed, and future research directions are proposed...