C M Niswender
Affiliation: University of Washington
- Identification and characterization of RNA editing events within the 5-HT2C receptorC M Niswender
Department of Pharmacology, Vanderbilt University School of Medicine, Nashville, Tennessee 37232 6600, USA
Ann N Y Acad Sci 861:38-48. 1998....
- RNA-editing of the 5-HT(2C) receptor alters agonist-receptor-effector coupling specificityK A Berg
Department of Pharmacology, Mail Code 7764, University of Texas Health Science Center, San Antonio, Texas, TX 78229 3900, USA
Br J Pharmacol 134:386-92. 2001..4. These results suggest an important role for the second intracellular loop in transmitting agonist-specific information to signalling molecules...
- RNA editing of the human serotonin 5-HT2C receptor. alterations in suicide and implications for serotonergic pharmacotherapyC M Niswender
Department of Pharmacology, Vanderbilt University, Nashville, TN 37232, USA
Neuropsychopharmacology 24:478-91. 2001..These findings suggest that alterations in RNA editing may contribute to or complicate therapy in certain psychiatric disorders...
- Recent advances in mammalian RNA editingC M Niswender
Department of Pharmacology, Vanderbilt University, Nashville, Tennessee 37232 6600, USA
Cell Mol Life Sci 54:946-64. 1998....
- A novel metabotropic glutamate receptor 5 positive allosteric modulator acts at a unique site and confers stimulus bias to mGlu5 signalingM J Noetzel
Department of Pharmacology and Vanderbilt Center for Neuroscience Drug Discovery, Nashville, TN, USA
Mol Pharmacol 83:835-47. 2013..Such stimulus bias by mGlu5 PAMs may complicate drug discovery efforts but would also allow for specifically tailored therapies, if pharmacological biases can be attributed to different therapeutic outcomes...