Affiliation: University of Michigan
- Evolutionary molecular medicineRandolph M Nesse
Department of Psychiatry, The University of Michigan, 3018 East Hall, 530 Church St, Ann Arbor, MI 48109, USA
J Mol Med (Berl) 90:509-22. 2012..This article reviews 15 evolutionary principles and their applications in molecular medicine in hopes that readers will use them and related principles to speed the development of evolutionary molecular medicine...
- Towards a genuinely medical model for psychiatric nosologyRandolph M Nesse
Department of Psychiatry, University of Michigan, Ann Arbor, MI 48109, USA
BMC Med 10:5. 2012..Dissatisfaction with psychiatric nosology may best be alleviated, not by new diagnostic criteria and categories, but by more realistic acknowledgment of the untidy landscape of mental and other medical disorders...
- Evolutionary approaches to sexually transmitted infectionsRandolph M Nesse
Department of Psychiatry, University of Michigan, Ann Arbor, Michigan 48109, USA
Ann N Y Acad Sci 1230:1-3. 2011..These and other applications of Darwinian medicine will improve understanding and treatment of sexually transmitted diseases...
- Evolution in health and medicine Sackler colloquium: Making evolutionary biology a basic science for medicineRandolph M Nesse
Department of Psychiatry and Psychology, University of Michigan, Room 3018, East Hall, 530 Church Street, Ann Arbor, MI 48104, USA
Proc Natl Acad Sci U S A 107:1800-7. 2010..Evolutionary biology is not just another topic vying for inclusion in the curriculum; it is an essential foundation for a biological understanding of health and disease...
- Evolution, emotions, and emotional disordersRandolph M Nesse
Department of Psychology, University of Michigan, Ann Arbor, MI 48109 1043, USA
Am Psychol 64:129-39. 2009..The prevalence of emotional disorders can be attributed to several evolutionary factors...
- Maladaptation and natural selectionRandolph M Nesse
Departments of Psychology and Psychiatry, University of Michigan, Ann Arbor, Michigan 48104, USA
Q Rev Biol 80:62-70. 2005..Williams Vision" may not yield a net benefit to the possessor, but it is invaluable for the species...
- Psychoactive drug use in evolutionary perspectiveR M Nesse
Department of Psychiatry and Institute for Social Research, University of Michigan, 5057 ISR, Post Office Box 1248, Ann Arbor, MI 48106 1248, USA
Science 278:63-6. 1997..A deeper understanding of the evolutionary origins and functions of the emotions and their neural mechanisms is needed as a basis for decisions about the use of psychoactive drugs...
- The smoke detector principle. Natural selection and the regulation of defensive responsesR M Nesse
Department of Psychiatry, University of Michigan, 426 Thompson St, Room 5057, Ann Arbor, MI 48104, USA
Ann N Y Acad Sci 935:75-85. 2001..The smoke detector principle is an essential foundation for making decisions about when drugs can be used safely to relieve suffering and block defenses...
- Emotional disorders in evolutionary perspectiveR Nesse
The University of Michigan, Ann Arbor 48106 1248, USA
Br J Med Psychol 71:397-415. 1998..An evolutionary understanding of individuals in terms of their relationship strategies and the social emotions offers great promise for psychotherapists...
- Proximate and evolutionary studies of anxiety, stress and depression: synergy at the interfaceR M Nesse
University of Michigan, Ann Arbor 48106 1248, USA
Neurosci Biobehav Rev 23:895-903. 1999....
- Is depression an adaptation?R M Nesse
Department of Psychiatry, University of Michigan, Ann Arbor 48106 1248, USA
Arch Gen Psychiatry 57:14-20. 2000..These hypotheses are consistent with considerable evidence and suggest specific tests...
- On the difficulty of defining disease: a Darwinian perspectiveR M Nesse
University of Michigan, Institute for Social Research, Room 5057, 426 Thompson Street, Ann Arbor, MI 48104, USA
Med Health Care Philos 4:37-46. 2001....
- Religion and emotional compensation: results from a prospective study of widowhoodStephanie L Brown
Institute for Social Research, The University of Michigan, Ann Arbor, MI 48106 1248, USA
Pers Soc Psychol Bull 30:1165-74. 2004..Finally, insecure individuals were most likely to benefit from increasing the importance of their beliefs. Results are discussed in terms of the potential value of applying psychological theory to the study of religion...
- Methodological innovations in the National Survey of American LifeJames S Jackson
Research Center for Group Dynamics, University of Michigan, USA
Int J Methods Psychiatr Res 13:289-98. 2004..Finally, an abbreviated, novel method for estimating the prevalence of mental disorders in first-degree family members is described and the preliminary results from this new approach are reported...
- The National Survey of American Life: a study of racial, ethnic and cultural influences on mental disorders and mental healthJames S Jackson
Research Center for Group Dynamics, University of Michigan, USA
Int J Methods Psychiatr Res 13:196-207. 2004..Unique features of sample design, including special screening and listing procedures, interviewer training and supervision, and response rate outcomes are described...
- Providing social support may be more beneficial than receiving it: results from a prospective study of mortalityStephanie L Brown
Institute for Social Research, The University of Michigan, Ann Arbor 48106 1248, USA
Psychol Sci 14:320-7. 2003..These results have implications for understanding how social contact influences health and longevity...
- Natural selection and the elusiveness of happinessRandolph M Nesse
Department of Psychiatry, Department of Psychology and Institute for Social Research, The University of Michigan, 426 Thompson Street, Room 5261, Ann Arbor, MI 48104, USA
Philos Trans R Soc Lond B Biol Sci 359:1333-47. 2004..Research on the evolutionary origins of the capacities for positive and negative emotions is urgently needed to provide a foundation for sensible decisions about the use of new mood-manipulating technologies...
- Psychological adjustment to sudden and anticipated spousal loss among older widowed personsD Carr
Institute for Social Research, University of Michigan, Ann Arbor, USA
J Gerontol B Psychol Sci Soc Sci 56:S237-48. 2001..g., predeath caregiving, nursing home use, spouse's age at death, and couple's communication about the death)...
- Evolution and addictionRandolph M Nesse
The University of Michigan, Department of Psychiatry, Ann Arbor 48104, USA
Addiction 97:470-1. 2002
- Resilience to loss and chronic grief: a prospective study from preloss to 18-months postlossGeorge A Bonanno
Department of Counseling and Clinical Psychology, Teachers College, Columbia University, New York, New York 10027, USA
J Pers Soc Psychol 83:1150-64. 2002..Chronic grief was associated with preloss dependency and resilience with preloss acceptance of death and belief in a just world...
- Prospective patterns of resilience and maladjustment during widowhoodGeorge A Bonanno
Department of Counseling and Clinical Psychology, Teachers College, Columbia University, New York, NY, USA
Psychol Aging 19:260-71. 2004..Both the resilient and the depressed-improved groups showed remarkably healthy profiles and relatively little evidence of either struggling with or denying/avoiding the loss...
- Vomiting is not an adaption for glaucoma (and Darwinian medicine is difficult)Sergiu P Paşca
Med Hypotheses 71:472-3. 2008
- What evolutionary biology offers public healthRandolph M Nesse
Bull World Health Organ 86:83. 2008
- The evolutionary significance of depressive symptoms: different adverse situations lead to different depressive symptom patternsMatthew C Keller
Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, Richmond, VA 23219, USA
J Pers Soc Psychol 91:316-30. 2006..These significant differences were replicated in an experiment in which 113 students were randomly assigned to visualize a major failure or the death of a loved one...
- Medicine needs evolutionRandolph M Nesse
Science 311:1071. 2006
- Is low mood an adaptation? Evidence for subtypes with symptoms that match precipitantsMatthew C Keller
Center for Society and Genetics UCLA, Box 951405, 1339 Murphy Hall, Los Angeles, CA, 90095, USA
J Affect Disord 86:27-35. 2005..To test this hypothesis, we examined how symptoms of low mood differ depending upon the precipitating situation, and whether these differences match expectations of symptoms useful in each kind of situation...
- Evolutionary health promotionS Boyd Eaton
Department of Anthropology, Emory University, 2887 Howell Mill Road NW, Atlanta, GA 30327, USA
Prev Med 34:109-18. 2002..3) Integrate epidemiological, mechanistic, and genetic data with evolutionary principles to create an overarching formulation upon which to base persuasive, consistent, and effective recommendations...
- QUESTIONS ABOUT BEREAVEMENT: ANSWERS FROM THE CLOC STUDYRandolph Nesse; Fiscal Year: 2001..We anticipate that this effort to make the data available to other researchers in a form that they can use will result in significant, and likely unforeseen, advances in our understanding of bereavement. ..