Fariborz Mortazavi

Summary

Affiliation: University of California
Country: USA

Publications

  1. pmc Significance of KRAS/PAK1/Crk pathway in non-small cell lung cancer oncogenesis
    Fariborz Mortazavi
    Division of Hematology Oncology, West Los Angeles VA, Los Angeles, CA, USA
    BMC Cancer 15:381. 2015
  2. doi p120-catenin is transcriptionally downregulated by FOXC2 in non-small cell lung cancer cells
    Fariborz Mortazavi
    Division of Hematology Oncology, Veterans Administration, Greater Los Angeles, West Los Angeles, California, USA
    Mol Cancer Res 8:762-74. 2010
  3. pmc c-Crk proto-oncogene contributes to transcriptional repression of p120-catenin in non-small cell lung cancer cells
    Fariborz Mortazavi
    Department of Medicine, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA
    Clin Exp Metastasis 28:391-404. 2011
  4. pmc PAK1 kinase promotes cell motility and invasiveness through CRK-II serine phosphorylation in non-small cell lung cancer cells
    Matthew Rettig
    Division of Hematology Oncology, West Los Angeles VA, Los Angeles, California, United States of America
    PLoS ONE 7:e42012. 2012

Collaborators

Detail Information

Publications4

  1. pmc Significance of KRAS/PAK1/Crk pathway in non-small cell lung cancer oncogenesis
    Fariborz Mortazavi
    Division of Hematology Oncology, West Los Angeles VA, Los Angeles, CA, USA
    BMC Cancer 15:381. 2015
    ..Key effector(s) of mutated KRAS in lung cancer progression and metastasis are unknown. Here we investigated the role of PAK1/Crk axis in transduction of the oncogenic KRAS signal in non-small cell lung cancer (NSCLC)...
  2. doi p120-catenin is transcriptionally downregulated by FOXC2 in non-small cell lung cancer cells
    Fariborz Mortazavi
    Division of Hematology Oncology, Veterans Administration, Greater Los Angeles, West Los Angeles, California, USA
    Mol Cancer Res 8:762-74. 2010
    ..In summary, our data support the notion that FOXC2 mediates the transcriptional repression of p120ctn in NSCLC...
  3. pmc c-Crk proto-oncogene contributes to transcriptional repression of p120-catenin in non-small cell lung cancer cells
    Fariborz Mortazavi
    Department of Medicine, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA
    Clin Exp Metastasis 28:391-404. 2011
    ..In summary, our data provide evidence for the role of c-Crk proto-oncogene in transcriptional repression of p120ctn that further clarifies the mechanism by which this biochemical signal promotes metastasis in NSCLC...
  4. pmc PAK1 kinase promotes cell motility and invasiveness through CRK-II serine phosphorylation in non-small cell lung cancer cells
    Matthew Rettig
    Division of Hematology Oncology, West Los Angeles VA, Los Angeles, California, United States of America
    PLoS ONE 7:e42012. 2012
    ..In summary, these data provide evidence for the role of PAK1 in the promotion of cell motility, cell invasiveness and the down regulation of p120-catenin through CRK serine 41 phosphorylation in NSCLC cells...