Genomes and Genes
Affiliation: University of Maryland
- High attributable risk of elevated C-reactive protein level to conventional coronary heart disease risk factors: the Third National Health and Nutrition Examination SurveyMichael Miller
Department of Medicine, University of Maryland School of Medicine, Baltimore, USA
Arch Intern Med 165:2063-8. 2005..However, the extent to which high CRP levels (>3 mg/L) may be attributable to high cholesterol levels and other CHD risk factors has not been well defined...
- Niacin as a component of combination therapy for dyslipidemiaMichael Miller
Center for Preventive Cardiology, University of Maryland Medical Center, Baltimore 21201, USA
Mayo Clin Proc 78:735-42. 2003..Adding niacin to lipid-lowering regimens is a valuable option for physicians treating patients with dyslipidemia and should be considered in appropriate patients...
- Genetics of HDL regulation in humansMichael Miller
Departments of Medicine and Epidemiology, Veterans Affairs and University of Maryland Medical Center, Baltimore, MD 21201, USA
Curr Opin Lipidol 14:273-9. 2003..To review gene regulation of HDL-cholesterol and discuss molecular abnormalities in HDL candidate genes that may lead to human pathologic states...
- Raising an isolated low HDL-C level: why, how, and when?Michael Miller
Center for Preventive Cardiology, Department of Medicine and Epidemiology, University of Maryland Medical Center, Baltimore 21201, USA
Cleve Clin J Med 70:553-60. 2003..While no current therapy is optimal, many can yield modest increases that translate into reduced risk for CHD events...
- Effect of desirable fasting triglycerides on the postprandial response to dietary fatMichael Miller
Division of Cardiology, Department of Medicine, Veterans Affairs Medical Center University of Maryland, Baltimore, MD 21201, USA
J Investig Med 51:50-5. 2003..The National Cholesterol Education Program (NCEP) recently revised the "desirable" fasting triglyceride (TG) to < 150 mg/dL, and levels exceeding 200 mg/dL are defined as "high."..
- Genetic determinants of low high-density lipoprotein cholesterolMichael Miller
Department of Medicine, University of Maryland Hospital and Veterans Affairs Medical Center, Baltimore, Maryland, USA
Curr Opin Cardiol 19:380-4. 2004..This review summarizes recent data involving HDL regulatory genes and their role in atherothrombosis...
- Update on the role of triglycerides as a risk factor for coronary heart diseaseMichael Miller
Department of Medicine, University of Maryland School of Medicine, 655 West Baltimore Street, Baltimore, MD 21201, USA
Curr Atheroscler Rep 4:414-8. 2002..However, an important yet unanswered question is whether decreasing triglycerides beyond low-density lipoprotein cholesterol lowering contributes significantly to additional coronary heart disease event reduction...
- Impact of triglyceride levels beyond low-density lipoprotein cholesterol after acute coronary syndrome in the PROVE IT-TIMI 22 trialMichael Miller
Division of Cardiology, University of Maryland Medical Center, Baltimore, Maryland 21201, USA
J Am Coll Cardiol 51:724-30. 2008..The purpose of this study was to assess the impact of on-treatment triglycerides (TG) on coronary heart disease (CHD) risk after an acute coronary syndrome (ACS)...
- Optimal treatment of dyslipidemia in high-risk patients: intensive statin treatment or combination therapy?Michael Miller
University of Maryland School of Medicine, Baltimore, MD 21201, USA
Prev Cardiol 10:31-5. 2007..Nonetheless, for residual elevation in triglycerides and/or reduced high-density lipoprotein cholesterol, adding a second agent (eg, fenofibrate, niacin) is a reasonable option...
- The effect of simvastatin on triglyceride-rich lipoproteins in patients with type 2 diabetic dyslipidemia: a SILHOUETTE trial sub-studyM Miller
University of Maryland Medical Center, Baltimore, Maryland, USA
Curr Med Res Opin 22:343-50. 2006..To determine if simvastatin effectively decreases the elevated levels of triglyceride (TG), TG-rich lipoproteins, and small, dense LDL particles, which are characteristic of diabetic dyslipidemia...
- Effectiveness of high doses of simvastatin as monotherapy in mixed hyperlipidemiaM Miller
Division of Cardiology, University of Maryland Medical Center, Baltimore, USA
Am J Cardiol 87:232-4, A9. 2001..The highest dose of simvastatin also resulted in significant increases in high-density lipoprotein cholesterol (21%) with a comparable increase in large, protective high-density lipoprotein particles...
- Prevalence of the APOC3 promoter polymorphisms T-455C and C-482T in Asian-IndiansM Miller
Division of Cardiology, University of Maryland Medical Center, Baltimore, USA
Am J Cardiol 87:220-1, A8. 2001..Polymorphisms in the APOC3 promoter (-455 T/C and -482 C/T) were frequently encountered in young Asian-Indians and they correlated with reduced concentrations of apolipoprotein A-I...
- Current perspectives on the management of hypertriglyceridemiaM Miller
University of Maryland Medical System, Baltimore, MD, USA
Am Heart J 140:232-40. 2000..There are considerable data that lowering LDL cholesterol reduces cardiovascular events. However, the importance of triglyceride lowering remains elusive...
- Sex bias and underutilization of lipid-lowering therapy in patients with coronary artery disease at academic medical centers in the United States and Canada. Prospective Randomized Evaluation of the Vascular Effects of Norvasc Trial (PREVENT) InvestigatorM Miller
Department of Medicine, University of Maryland Medical Center, Baltimore, USA
Arch Intern Med 160:343-7. 2000..However, limited information is available assessing the extent to which these medications are prescribed in academic medical centers...
- Bezafibrate reduces the incidence of type 2 diabetes mellitus in patients with obesityMichael Miller
University of Maryland Medical Center, Baltimore, MD, USA
Nat Clin Pract Endocrinol Metab 2:198-9. 2006
- Novel polypyrimidine variation (IVS46: del T -39...-46) in ABCA1 causes exon skipping and contributes to HDL cholesterol deficiency in a family with premature coronary diseaseSeung Ho Hong
Department of Medicine, University of Maryland and Veterans Administration Medical Center, Baltimore, MD, USA
Circ Res 93:1006-12. 2003....
- Apolipoprotein A-I(Zavalla) (Leu159-->Pro): HDL cholesterol deficiency in a kindred associated with premature coronary artery diseaseM Miller
Department of Medicine, University of Maryland School of Medicine, Veterans Affairs Medical Center, Baltimore, USA
Arterioscler Thromb Vasc Biol 18:1242-7. 1998..In addition, it extends recent observations that HDL-C deficiency states may be more prone to the development of premature coronary artery disease when accompanied by additional cardiovascular risk factors...
- Genotypic variation in ATP-binding cassette transporter-1 (ABCA1) as contributors to the high and low high-density lipoprotein-cholesterol (HDL-C) phenotypeMyrna Mantaring
Department of Medicine, University of Maryland Medical Center and VA Maryland Health Care System, Baltimore, MD, USA
Transl Res 149:205-10. 2007..0002, respectively) compared with lower HDL-C. These data reaffirm that rare mutations in ABCA1 are associated with low HDL-C. However, at least 1 ABCA1 polymorphism (eg, E1172D) may contribute to the high HDL-C phenotype...
- ABCA1(Alabama): a novel variant associated with HDL deficiency and premature coronary artery diseaseSeung Ho Hong
Section of Cardiology, Department of Medicine, University of Maryland and Veterans Administration Medical Center, 22 S Greene St, S3B06, Baltimore, MD 21201, USA
Atherosclerosis 164:245-50. 2002..These data confirm recent data that a single defective allele in ABCA1 may be associated with reduced HDL cholesterol and FHA...
- Malnutrition-inflammation modifies the relationship of cholesterol with cardiovascular diseaseGabriel Contreras
Department of Medicine, Division of Nephrology and Hypertension, University of Miami Miller School of Medicine, 1120 NW 14th Street, Suite 360E, Miami, FL 33136, USA
J Am Soc Nephrol 21:2131-42. 2010..In the M-I group, the corresponding HRs did not vary significantly by cholesterol level. In conclusion, the presence of M-I modifies the risk relationship between cholesterol level and CVD in African Americans with hypertensive CKD...
- Normal triglyceride levels and coronary artery disease events: the Baltimore Coronary Observational Long-Term StudyM Miller
Division of Cardiology, University of Maryland School of Medicine, Baltimore 21201 1595, USA
J Am Coll Cardiol 31:1252-7. 1998..This study sought to evaluate long-term predictors of coronary events in men and women with arteriographically defined coronary artery disease (CAD)...
- The role of triglycerides in cardiovascular riskPuneet Gandotra
Department of Medicine, University of Maryland Hospital, Division of Cardiology, Room S3B06, 22 South Greene Street, Baltimore, MD 21201, USA
Curr Cardiol Rep 10:505-11. 2008..However, reducing very high triglycerides (ie, > 500 mg/dL) remains a sufficiently high priority in affected individuals...
- Lecithin: cholesterol acyltransferase deficiency: identification of two defective alleles in fibroblast cDNAM Miller
Department of Medicine, Veterans Administration Medical Center, Baltimore, MD 21201, USA
J Lipid Res 36:931-8. 1995..Expression studies of mutant LCAT cDNA confirmed the virtual absence of LCAT activity in transfected COS-1 cells. The molecular defect in a young male with complete LCAT deficiency has been identified using fibroblast cDNA...
- Novel ABCA1 compound variant associated with HDL cholesterol deficiencySeung Ho Hong
Department of Medicine, University of Maryland and Veterans Administration Medical Center, 22 S Greene St, S3B06 Baltimore 21201, USA
Biochim Biophys Acta 1587:60-4. 2002..Direct sequencing of all coding regions and splice site junctions of other HDL candidate genes revealed no additional mutations, indicating that combined defective ABCA1 alleles may result in familial HDL deficiency...
- The two novel CETP mutations Gln87X and Gln165X in a compound heterozygous state are associated with marked hyperalphalipoproteinemia and absence of significant coronary artery diseaseJeffrey Rhyne
University of Maryland and Veterans Affairs Medical Center, Baltimore, MD, USA
J Mol Med (Berl) 84:647-50. 2006..However, it remains unclear as to whether the relative lack of coronary atherosclerosis was the direct consequence of CETP deficiency and/or the lack of traditional CAD risk factors...
- Impact of lowering triglycerides on raising HDL-C in hypertriglyceridemic and non-hypertriglyceridemic subjectsMichael Miller
Department of Medicine, University of Maryland Medical Center and Veterans Affairs Medical Center, Baltimore, MD, United States
Int J Cardiol 119:192-5. 2007..These data indicate that lowering TG is independently and inversely correlated with HDL-C, effects that are most pronounced in the absence of hypertriglyceridemia...
- Do mutations causing low HDL-C promote increased carotid intima-media thickness?Michael Miller
University of Maryland Hospital and Veterans Affairs Medical Center, Baltimore, MD 21201, United States
Clin Chim Acta 377:273-5. 2007..Although observational data support an inverse relationship between high-density lipoprotein (HDL) cholesterol and coronary heart disease (CHD), genetic HDL deficiency states often do not correlate with premature CHD...
- Managing mixed dyslipidemia in special populationsMichael Miller
Department of Medicine, University of Maryland Hospital, Baltimore, MD, USA
Prev Cardiol 13:78-83. 2010..However, while combination therapy may successfully correct the associated dyslipidemia, it remains to be established whether the addition of a second agent improves coronary risk beyond statin monotherapy...
- Divergent effects of joyful and anxiety-provoking music on endothelial vasoreactivityMichael Miller
Division of Cardiology, University of Maryland Medical Center, Baltimore, Maryland 21201, USA
Psychosom Med 72:354-6. 2010..To evaluate the extent to which music may affect endothelial function. In previous research, a link between music and physiologic parameters such as heart rate and blood pressure has been observed...
- Baseline disease activity, hyperlipidemia, and hypertension are predictive factors for ischemic stroke and stroke severity in systemic lupus erythematosusJamal Mikdashi
Division of Rheumatology and Clinical Immunology, University of Maryland School of Medicine, 10 South Pine Street, Suite 834, Baltimore, MD 21201, USA
Stroke 38:281-5. 2007..To determine factors associated with ischemic stroke and stroke severity in patients with systemic lupus erythematosus...
- Comparative effects of three popular diets on lipids, endothelial function, and C-reactive protein during weight maintenanceMichael Miller
Divisionof Cardiology, University of Maryland Hospital, Room S3B06, 22 S Greene St, Baltimore, MD 21201, USA
J Am Diet Assoc 109:713-7. 2009....
- APOC3 promoter polymorphisms C-482T and T-455C are associated with the metabolic syndromeMichael Miller
University of Maryland Hospital and Veterans Affairs Medical Center, Baltimore, Maryland, USA
Arch Med Res 38:444-51. 2007..One candidate, APOC3, modulates lipid and lipoprotein metabolism and the promoter polymorphisms C-482T/T-455C are associated with loss of insulin downregulation...
- Relative atherogenicity and predictive value of non-high-density lipoprotein cholesterol for coronary heart diseaseMichael Miller
Division of Cardiology, University of Maryland Medical Center, Baltimore, MD, USA
Am J Cardiol 101:1003-8. 2008..In conclusion, non-HDL-C remains an important target of therapy for patients with elevated TGs, although its widespread adoption has yet to gain a foothold among health care professionals treating patients with dyslipidemia...
- The effect of mirthful laughter on the human cardiovascular systemMichael Miller
Department of Medicine, Division of Cardiology, University of Maryland Medical Center, Baltimore, MD 21201, USA
Med Hypotheses 73:636-9. 2009..This article reviews the relevant physiology and comments on the potentially wider clinical implications in the integration of this process to improve vascular health...
- A null mutation in human APOC3 confers a favorable plasma lipid profile and apparent cardioprotectionToni I Pollin
Department of Medicine, University of Maryland School of Medicine, Baltimore, MD 21201, USA
Science 322:1702-5. 2008..Subclinical atherosclerosis, as measured by coronary artery calcification, was less common in carriers than noncarriers, which suggests that lifelong deficiency of apoC-III has a cardioprotective effect...
- An emerging paradigm in atherosclerosis: focus on subclinical diseaseMichael Miller
University of Maryland School of Medicine, Center for Preventive Cardiology, Division of Cardiology, University of Maryland Medical Center, Baltimore, MD 21201, USA
Postgrad Med 121:49-59. 2009..The unique combination of benefits provided by statin therapy may have an application in treating subclinical atherosclerotic disease...
- Multiple splice defects in ABCA1 cause low HDL-C in a family with hypoalphalipoproteinemia and premature coronary diseaseJeffrey Rhyne
Department of Medicine, Cardiology Division, University Maryland Medical Center and Baltimore Veterans Affairs Medical Center, 22 South Greene Street, Baltimore, MD 21201, USA
BMC Med Genet 10:1. 2009..We screened DNA from a 41 year-old male with low HDL-C (12 mg/dL [0.31 mmol/L]) and a family history of premature coronary heart disease (CHD) using polymerase chain reaction single-strand conformation polymorphism (SSCP) analysis...
- Dyslipidemia and cardiovascular risk: the importance of early preventionM Miller
Center for Preventive Cardiology, Division of Cardiology, University of Maryland Medical Center, Baltimore, MD 21201, USA
QJM 102:657-67. 2009..Therefore, data from ongoing prospective studies will hopefully resolve this issue and facilitate identification of optimal strategies to augment CV risk reduction...
- Serum metalloproteinase leukolysin (MMP-25/MT-6): a potential metabolic marker for atopy-associated inflammationM N Blumenthal
Department of Medicine, The Asthma and Allergy Center, University of Minnesota Medical School, Minneapolis, MN 55455, USA
Clin Exp Allergy 40:859-66. 2010..Leukolysin is a novel matrix metalloproteinase (MMP-25/MT-6) released mainly by granulocytic cells, primarily neutrophils, which are implicated in chronic airways inflammation...
- Alternative splicing in lecithin:cholesterol acyltransferase mRNA: an evolutionary paradigm in humans and great apesM Miller
Department of Medicine, Veterans Affairs Medical Center and University of Maryland Medical Center, Baltimore 21201, USA
Gene 190:309-13. 1997..These results demonstrate that alternative splicing of LCAT mRNA is variant among primates and suggest a potential role of Alu elements in the evolutionary diversity of proteins...
- Lack of association between increased carotid intima-media thickening and decreased HDL-cholesterol in a family with a novel ABCA1 variant, G2265TSeung Ho Hong
Department of Medicine, University of Maryland and Veterans Administration Medical Center, Baltimore, MD 21201, USA
Clin Chem 48:2066-70. 2002..Although these data extend previous observations that a single defective ABCA1 allele may lead to decreased HDL-C, associated evidence of early atherosclerosis was not confirmed...
- Low high-density lipoprotein cholesterol: an important consideration in coronary heart disease risk assessmentFarhan Majeed
Department of Medicine, University of Maryland Medical Center, Baltimore, Maryland 21201, USA
Curr Opin Endocrinol Diabetes Obes 15:175-81. 2008..Other aims are to explore the mechanisms underlying the reported cardioprotective effects of high-density lipoprotein and to evaluate therapeutic modalities to increase high-density lipoprotein levels and functionality...
- Effectiveness of simvastatin therapy in raising HDL-C in patients with type 2 diabetes and low HDL-CMichael Miller
University of Maryland Medical Center, Baltimore, MD, USA
Curr Med Res Opin 20:1087-94. 2004....
- A novel TC deletion resulting in Pro(260)-->Stop in the human LCAT gene is associated with a dominant effect on HDL-cholesterolA Kasid
Department of Medicine, University of Maryland School of Medicine, 22 South Greene Street, Baltimore, MD 21201, USA
Atherosclerosis 156:127-32. 2001....
- Hyponatremia: age-related risk factors and therapy decisionsM Miller
Levindale Hebrew Geriatric Center and Hospital, Baltimore, USA
Geriatrics 53:32-3, 37-8, 41-2 passim. 1998..Awareness of these risk factors allows the physician to anticipate the impact of illnesses and drugs on volume and electrolyte status of the older patient and to implement a rational approach to therapeutic intervention and management...
- Phase i/ii trial of the pharmacokinetics, safety, and antiretroviral activity of tenofovir disoproxil fumarate in human immunodeficiency virus-infected adultsP Barditch-Crovo
The Johns Hopkins University School of Medicine, 600 N Wolfe St, Baltimore, MD 21287, USA
Antimicrob Agents Chemother 45:2733-9. 2001..No patients developed detectable sequence changes in the reverse transcriptase gene...
- Family-based association of YWHAH in psychotic bipolar disorderDeepak Grover
Department of Psychiatry, Johns Hopkins School of Medicine, Baltimore, Maryland 21287, USA
Am J Med Genet B Neuropsychiatr Genet 150:977-83. 2009....
- Effect of statins on platelet PAR-1 thrombin receptor in patients with the metabolic syndrome (from the PAR-1 inhibition by statins [PARIS] study)Victor L Serebruany
HeartDrug Research Laboratories, Johns Hopkins University, Towson, MD, USA
Am J Cardiol 97:1332-6. 2006..These observational data offer a plausible mechanism for the recently demonstrated pleiotropic effects of statins that may contribute to early clinical benefit...
- Effects of simvastatin (40 and 80 mg) on highly sensitive C-reactive protein in patients with combined hyperlipidemiaMichael Miller
University of Maryland and Veterans Affairs Medical Center, Baltimore, Maryland, USA
Am J Cardiol 89:468-9. 2002
- Exercise-induced hypertension, endothelial dysfunction, and coronary artery disease in a marathon runnerRadha Goel
Department of Medicine, Duke University School of Medicine, Durham, North Carolina, USA
Am J Cardiol 99:743-4. 2007..In conclusion, vigorous aerobic activity in susceptible individuals may promote oxidative stress and coronary atherosclerosis...
- The role of the phospholipid sphingomyelin in heart diseaseSubroto Chatterjee
Department of Pediatrics, Johns Hopkins University, Baltimore, MD 21205, USA
Curr Opin Investig Drugs 7:219-28. 2006..Further studies of the molecular and pathobiological basis of these phospholipids may facilitate advances in the discovery of drugs with which to mitigate diseases that may result from an elevation in SM and its metabolites...
- Pattern separation in the human hippocampal CA3 and dentate gyrusArnold Bakker
Department of Psychological and Brain Sciences, Johns Hopkins University, Baltimore, MD, USA
Science 319:1640-2. 2008..These results provide compelling evidence of a key role of the human CA3/dentate gyrus in pattern separation...
- Research pointers: Platelet responsiveness to aspirin in patients with hyperlipidaemiaMaribeth Friend
Department of Medical and Research Technology and Medicine, University of Maryland Medical Center, Baltimore, MD 21201, USA
BMJ 326:82-3. 2003
- Lipid levels in the post-acute coronary syndrome setting: destabilizing another myth?Michael Miller
J Am Coll Cardiol 51:1446-7. 2008
- Intensive versus moderate lipid lowering with statins after acute coronary syndromesMichael Miller
N Engl J Med 351:714-7; author reply 714-7. 2004
- Hypertriglyceridemia and cardiovascular risk reductionTerry A Jacobson
Office of Health Promotion and Disease Prevention, Emory University, Atlanta, GA 30303, USA
Clin Ther 29:763-77. 2007..There is evidence that elevated TG levels may be a significant independent risk factor for coronary heart disease (CHD), particularly in women...
- High prevalence of C-reactive protein elevation with normal triglycerides (100-149 mg/dL): are triglyceride levels below 100 mg/dL more optimal in coronary heart disease risk assessment?Irfan Ahmad
School of Public Health, Yale University, New Haven, Connecticut, USA
Am J Med Sci 329:173-7. 2005..The National Cholesterol Education Program defines a fasting triglyceride level below 150 mg/dL as normal. However, observational data suggest that triglyceride levels above 100 mg/dL may predict coronary heart disease (CHD) events...
- Role of LCAT in HDL remodeling: investigation of LCAT deficiency statesBela F Asztalos
Lipid Metabolism Laboratory, Jean Mayer US Department of Agriculture Human Nutrition Research Center on Aging at Tufts University, Boston, MA, USA
J Lipid Res 48:592-9. 2007....
- Long-term user perceptions of an implanted neuroprosthesis for exercise, standing, and transfers after spinal cord injurySanjeev Agarwal
Department of Orthopaedic Surgery, Case Western Reserve University School of Medicine, Cleveland, OH, USA
J Rehabil Res Dev 40:241-52. 2003..The implanted standing neuroprosthesis appears to be a clinically acceptable and effective means of providing the ability to exercise, stand, and transfer to selected individuals with paraplegia or low tetraplegia...
- Hepatitis B virus genotypes and virologic response in 694 patients in phase III studies of adefovir dipivoxil1Chris Westland
Gilead Sciences, Foster City, California 94404, USA
Gastroenterology 125:107-16. 2003..Antiviral efficacy of adefovir dipivoxil 10-mg therapy was examined with respect to HBV genotype, hepatitis B e antigen (HBeAg) serostatus, and race...
- High efficiency transgene segregation in co-transformed maize plants using an Agrobacterium tumefaciens 2 T-DNA binary systemMichael Miller
Pioneer Hi Bred International Inc, Johnston, Iowa 50131, USA
Transgenic Res 11:381-96. 2002..A high efficiency system to segregate transgenes in co-transformed maize plants has now been demonstrated...
- Ethyl glucuronide: a biomarker to identify alcohol use by health professionals recovering from substance use disordersGregory E Skipper
Alabama Physician Health Program and University of Alabama Birmingham School of Medicine, Montgomery, Alabama, USA
Alcohol Alcohol 39:445-9. 2004..Ethyl glucuronide (EtG), a direct metabolite of alcohol, offers an extended window for assessment of drinking status (up to 5 days). Our aim was to assess the potential value of EtG testing in abstinence-based monitoring programs...
- Clinically validated genotype analysis: guiding principles and statistical concernsFrancoise Brun-Vezinet
Hospital Bichat Claude Bernard, Paris, France
Antivir Ther 9:465-78. 2004....
- Prevalence of nursing home-associated infections in the Department of Veterans Affairs nursing home care unitsLinda Tsan
Office of Medical Inspector, Department of Veterans Affairs Central Office, Washington, DC 20402, USA
Am J Infect Control 36:173-9. 2008..The Department of Veterans Affairs (VA) is the largest single provider of long-term care in the United States. The prevalence of nursing home-associated infections (NHAIs) among residents of VA nursing home care units (NHCUs) is not known...
- Semi-automated basal ganglia segmentation using large deformation diffeomorphic metric mappingAli Khan
School of Engineering Science, Simon Fraser University, 8888 University Drive, Burnaby BC, V5A 1S6, Canada
Med Image Comput Comput Assist Interv 8:238-45. 2005..Our accuracy is compared against gold-standard manual segmentations and various automated segmentation tools through the use of several error metrics...
- Omega-3 fatty acids and coronary heart disease risk: clinical and mechanistic perspectivesWilliam S Harris
Nutrition and Metabolic Disease Research, Sanford Research USD, Sanford School of Medicine, University of South Dakota, Sioux Falls, SD 57105, USA
Atherosclerosis 197:12-24. 2008..Our focus is to review the potential mechanisms by which these fatty acids reduce cardiovascular disease risk...
- Targeting glucose in acute myocardial infarction: has glucose, insulin, and potassium infusion missed the target?Ajay Chaudhuri
Department of Endocrinology, State University at New York at Buffalo and Kaleida Health, Buffalo, New York, USA
Diabetes Care 30:3026-8. 2007
- Organizational Readiness for Change and opinions toward treatment innovationsBret E Fuller
Oregon Health and Science University, Portland, OR 97239, USA
J Subst Abuse Treat 33:183-92. 2007..The analysis provides evidence of the ORC's utility in assessing agency strengths and needs during the implementation of evidence-based practices...
- A 19-month-old girl with congestive heart failure, hypertension, and coronary artery dilatations. Interview by Robert ListernickDenise Goodman
Pediatr Ann 34:14, 16, 17-9. 2005
- Resistance to chronic wasting disease in transgenic mice expressing a naturally occurring allelic variant of deer prion proteinKimberly Meade-White
Laboratory of Persistent Viral Diseases, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases NIH, 903 South Fourth Street, Hamilton, MT 59840, USA
J Virol 81:4533-9. 2007....
- Direct care workers in the National Drug Abuse Treatment Clinical Trials Network: characteristics, opinions, and beliefsDennis McCarty
Department of Public Health and Preventive Medicine, Oregon Health and Science University, 3181 SW Sam Jackson Park Rd, Portland, OR 97239, USA
Psychiatr Serv 58:181-90. 2007..Individuals with direct care responsibilities in 348 drug abuse treatment units were surveyed to obtain a description of the workforce and to assess support for evidence-based therapies...
- Comprehensive linkage and linkage heterogeneity analysis of 4344 sibling pairs affected with hypertension from the Family Blood Pressure ProgramTiffany A Greenwood
Polymorphism Research Laboratory, Department of Psychiatry, University of California, San Diego, La Jolla, California 92093 0603, USA
Genet Epidemiol 31:195-210. 2007..Ultimately our results suggest that evidence for linkage heterogeneity can only be detected with large sample sizes, such as the FBPP, which is consistent with theoretical sample size calculations...
- Comparative selection of the K65R and M184V/I mutations in human immunodeficiency virus type 1-infected patients enrolled in a trial of first-line triple-nucleoside analog therapy (Tonus IMEA 021)Christophe Delaunay
Laboratoire de Virologie, Hopital Bichat Claude Bernard, Paris, France
J Virol 79:9572-8. 2005..This convergent genetic pathway to resistance, associated with lower antiretroviral potency, may explain the high selection rate of these mutations in this trial...
- Angiographic diagnosis and endovascular management of nonvariceal gastrointestinal hemorrhageMichael Miller
Department of Radiology, Duke University Medical Center, Durham, NC 27710, USA
Gastroenterol Clin North Am 34:735-52. 2005..To that end, there is a great need for scientific data regarding the safety and efficacy of transcatheter therapy for upper and lower GI bleeding...
- [Angiosarcoma of the liver as a rare cause of rapidly progressive liver failure]Alisan Kahraman
Klinik für Gastroenterologie und Hepatologie, Universitatsklinikum Essen, Hufelandstrasse 55, 45122 Essen
Med Klin (Munich) 101:746-50. 2006..Angiosarcoma of the liver is a rare, highly malignant and sometimes diffusely infiltrating vessel tumor with rapid progression and poor prognosis...