Bruce L Miller

Summary

Affiliation: University of California
Country: USA

Publications

  1. ncbi request reprint International approaches to frontotemporal dementia diagnosis: from social cognition to neuropsychology
    Bruce L Miller
    UCSF Memory and Aging Center, San Francisco, CA, USA
    Ann Neurol 54:S7-10. 2003
  2. ncbi request reprint Accuracy of the clinical evaluation for frontotemporal dementia
    Mario F Mendez
    Department of Neurology, University of California at Los Angeles, USA
    Arch Neurol 64:830-5. 2007
  3. pmc Neuropsychological correlates of dominance, warmth, and extraversion in neurodegenerative disease
    Marc Sollberger
    Memory and Aging Center, UCSF Department of Neurology, University of California San Francisco, 350 Parnassus Avenue, San Francisco, CA 94143 1207, USA
    Cortex 48:674-82. 2012
  4. ncbi request reprint Performance in specific language tasks correlates with regional volume changes in progressive aphasia
    Serena Amici
    Department of Neurology, Memory and Aging Center, University of California, San Francisco, USA
    Cogn Behav Neurol 20:203-11. 2007
  5. pmc Greater medial temporal hypometabolism and lower cortical amyloid burden in ApoE4-positive AD patients
    Manja Lehmann
    Department of Neurology, Memory and Aging Center, University of California, San Francisco, California, USA
    J Neurol Neurosurg Psychiatry 85:266-73. 2014
  6. pmc Clinical-neuroimaging characteristics of dysexecutive mild cognitive impairment
    Judy Pa
    Memory and Aging Center, Department of Neurology, University of California, San Francisco, CA 94117, USA
    Ann Neurol 65:414-23. 2009
  7. pmc Interpersonal traits change as a function of disease type and severity in degenerative brain diseases
    Marc Sollberger
    Memory and Aging Center, University of California, San Francisco, CA 94143 1207, USA
    J Neurol Neurosurg Psychiatry 82:732-9. 2011
  8. pmc Frontotemporal dementia in a Brazilian kindred with the c9orf72 mutation
    Leonel T Takada
    Memory and AgingCenter, University of California, San Francisco, 350 Parnassus Ave, Ste 905, San Francisco, CA 94143 1207, USA
    Arch Neurol 69:1149-53. 2012
  9. pmc Different regional patterns of cortical thinning in Alzheimer's disease and frontotemporal dementia
    An Tao Du
    Center for Imaging of Neurodegenerative Diseases, Department of Veterans Affairs Medical Center, San Francisco, CA 94121, USA
    Brain 130:1159-66. 2007
  10. pmc The neural basis of surface dyslexia in semantic dementia
    Stephen M Wilson
    Department of Neurology, Memory and Aging Center, University of California, San Francisco, San Francisco, CA 94143 1207, USA
    Brain 132:71-86. 2009

Detail Information

Publications121 found, 100 shown here

  1. ncbi request reprint International approaches to frontotemporal dementia diagnosis: from social cognition to neuropsychology
    Bruce L Miller
    UCSF Memory and Aging Center, San Francisco, CA, USA
    Ann Neurol 54:S7-10. 2003
  2. ncbi request reprint Accuracy of the clinical evaluation for frontotemporal dementia
    Mario F Mendez
    Department of Neurology, University of California at Los Angeles, USA
    Arch Neurol 64:830-5. 2007
    ..Without a definitive clinical test, the early diagnosis of frontotemporal dementia (FTD) can be difficult...
  3. pmc Neuropsychological correlates of dominance, warmth, and extraversion in neurodegenerative disease
    Marc Sollberger
    Memory and Aging Center, UCSF Department of Neurology, University of California San Francisco, 350 Parnassus Avenue, San Francisco, CA 94143 1207, USA
    Cortex 48:674-82. 2012
    ..In this study, we hypothesized that different combinations of cognitive, neuropsychiatric, and emotional measures would predict different interpersonal traits in patients with neurodegenerative diseases...
  4. ncbi request reprint Performance in specific language tasks correlates with regional volume changes in progressive aphasia
    Serena Amici
    Department of Neurology, Memory and Aging Center, University of California, San Francisco, USA
    Cogn Behav Neurol 20:203-11. 2007
    ..Patterns of language impairment have long been used clinically to localize brain damage in stroke patients. The same approach might be useful in the differential diagnosis of progressive aphasia owing to neurodegenerative disease...
  5. pmc Greater medial temporal hypometabolism and lower cortical amyloid burden in ApoE4-positive AD patients
    Manja Lehmann
    Department of Neurology, Memory and Aging Center, University of California, San Francisco, California, USA
    J Neurol Neurosurg Psychiatry 85:266-73. 2014
    ..We aimed to assess the relationship between amyloid deposition, glucose metabolism and ApoE4 genotype in a clinically heterogeneous population of AD patients...
  6. pmc Clinical-neuroimaging characteristics of dysexecutive mild cognitive impairment
    Judy Pa
    Memory and Aging Center, Department of Neurology, University of California, San Francisco, CA 94117, USA
    Ann Neurol 65:414-23. 2009
    ..The goal of the study was to compare clinical and neuroimaging characteristics of two single-domain MCI subgroups: amnestic MCI and dysexecutive MCI...
  7. pmc Interpersonal traits change as a function of disease type and severity in degenerative brain diseases
    Marc Sollberger
    Memory and Aging Center, University of California, San Francisco, CA 94143 1207, USA
    J Neurol Neurosurg Psychiatry 82:732-9. 2011
    ....
  8. pmc Frontotemporal dementia in a Brazilian kindred with the c9orf72 mutation
    Leonel T Takada
    Memory and AgingCenter, University of California, San Francisco, 350 Parnassus Ave, Ste 905, San Francisco, CA 94143 1207, USA
    Arch Neurol 69:1149-53. 2012
    ....
  9. pmc Different regional patterns of cortical thinning in Alzheimer's disease and frontotemporal dementia
    An Tao Du
    Center for Imaging of Neurodegenerative Diseases, Department of Veterans Affairs Medical Center, San Francisco, CA 94121, USA
    Brain 130:1159-66. 2007
    ..In conclusion, the characteristic patterns of cortical thinning in Alzheimer's disease and FTD suggest that cortical thickness may be a useful surrogate marker for these types of dementia...
  10. pmc The neural basis of surface dyslexia in semantic dementia
    Stephen M Wilson
    Department of Neurology, Memory and Aging Center, University of California, San Francisco, San Francisco, CA 94143 1207, USA
    Brain 132:71-86. 2009
    ....
  11. pmc Effects of Alzheimer disease on fronto-parietal brain N-acetyl aspartate and myo-inositol using magnetic resonance spectroscopic imaging
    Xiaoping Zhu
    Department of Radiology, VA Medical Center, University of California, San Francisco, CA 94121, USA
    Alzheimer Dis Assoc Disord 20:77-85. 2006
    ..However, the NAA and mI changes are not correlated with each other, suggesting that they represent different processes that might help staging of AD...
  12. pmc Divergent network connectivity changes in behavioural variant frontotemporal dementia and Alzheimer's disease
    Juan Zhou
    Memory and Aging Center, Department of Neurology, University of California, San Francisco, CA 94117, USA
    Brain 133:1352-67. 2010
    ..Further developed, intrinsic connectivity network signatures may provide simple, inexpensive, and non-invasive biomarkers for dementia differential diagnosis and disease monitoring...
  13. pmc Frontal paralimbic network atrophy in very mild behavioral variant frontotemporal dementia
    William W Seeley
    UCSF Memory and Aging Center, University of California San Francisco, 350 Parnassus Avenue, San Francisco, CA 94143 1207, USA
    Arch Neurol 65:249-55. 2008
    ..Behavioral variant frontotemporal dementia (bvFTD) strikes hardest at the frontal lobes, but the sites of earliest injury remain unclear...
  14. pmc Rule violation errors are associated with right lateral prefrontal cortex atrophy in neurodegenerative disease
    Katherine L Possin
    Department of Neurology, University of California San Francisco, San Francisco, California, USA
    J Int Neuropsychol Soc 15:354-64. 2009
    ..These data underscore the importance of right lateral PFC in behavioral monitoring and highlight the potential of RV error assessment for identifying patients with damage to this region...
  15. pmc Oculomotor function in frontotemporal lobar degeneration, related disorders and Alzheimer's disease
    Siobhan Garbutt
    Memory and Aging Center, Department of Neurology, University of California, San Francisco, CA 94143 1207, USA
    Brain 131:1268-81. 2008
    ..These data suggest that oculomotor assessment may aid in the diagnosis of FTLD and related disorders...
  16. pmc Neural correlates of syntactic processing in the nonfluent variant of primary progressive aphasia
    Stephen M Wilson
    Memory and Aging Center, Department of Neurology, University of California, San Francisco, California 94143, USA
    J Neurosci 30:16845-54. 2010
    ..We conclude that in nonfluent PPA, the posterior IFC is not only structurally damaged, but also functionally abnormal, suggesting a critical role for this region in the breakdown of syntactic processing in this syndrome...
  17. pmc Frontotemporal dementia due to C9ORF72 mutations: clinical and imaging features
    Sharon J Sha
    Department of Neurology, University of California, San Francisco, USA
    Neurology 79:1002-11. 2012
    ..To describe the phenotype of patients with C9FTD/ALS (C9ORF72) hexanucleotide repeat expansion...
  18. pmc Anterior temporal lobe degeneration produces widespread network-driven dysfunction
    Christine C Guo
    1 Memory and Ageing Centre, Department of Neurology, University of California, San Francisco, USA
    Brain 136:2979-91. 2013
    ..The findings provide a neurophysiological basis for the theory that semantic processing is orchestrated through interactions between a critical anterior temporal lobe hub and modality-selective processing nodes. ..
  19. pmc Longitudinal MRI and cognitive change in healthy elderly
    Joel H Kramer
    Department of Neurology, San Francisco Medical Center, University of California, San Francisco, CA 94143, USA
    Neuropsychology 21:412-8. 2007
    ..The association between WMSH and EXEC further highlights the cognitive sequealae associated with cerebrovascular disease in normal elderly...
  20. ncbi request reprint Neuroanatomical correlates of impaired recognition of emotion in dementia
    Howard J Rosen
    University of California at San Francisco Department of Neurology, Memory and Aging Center, 350 Parnassus Avenue, Suite 706, Box 1207, San Francisco, CA 94143 1207, USA
    Neuropsychologia 44:365-73. 2006
    ....
  21. pmc Anti-saccade performance predicts executive function and brain structure in normal elders
    Jacob B Mirsky
    Department of Neurology, Memory and Aging Center, University of California, San Francisco, CA 94143, USA
    Cogn Behav Neurol 24:50-8. 2011
    ..To assess the neuropsychological and anatomical correlates of anti-saccade (AS) task performance in normal elders...
  22. pmc Language networks in semantic dementia
    Federica Agosta
    Memory and Aging Center, Department of Neurology, University of California, San Francisco, 350 Parnassus Avenue, Suite 905, San Francisco, CA 94143 1207, USA
    Brain 133:286-99. 2010
    ....
  23. pmc White matter damage in frontotemporal dementia and Alzheimer's disease measured by diffusion MRI
    Yu Zhang
    Center for Imaging of Neurodegenerative Diseases, Department of Veterans Affairs Medical Center, San Francisco, CA 94121, USA
    Brain 132:2579-92. 2009
    ..Taken together, the results suggest that white matter degradation measured with DTI may improve the diagnostic differentiation between FTD and Alzheimer's disease...
  24. pmc Age effects on atrophy rates of entorhinal cortex and hippocampus
    An Tao Du
    Magnetic Resonance Unit 114M, Department of Veterans Affairs Medical Center, 4150, Clement Street, San Francisco, CA 94121, USA
    Neurobiol Aging 27:733-40. 2006
    ..In conclusion, age and presence of lacunes should be taken into consideration in imaging studies of CN subjects and AD patients to predict AD progression and assess the response to treatment trials...
  25. pmc Frontotemporal dementia in eight Chinese individuals
    Steven Z Chao
    Department of Neurology, Memory and Aging Center, University of California San Francisco, San Francisco, CA, USA
    Neurocase 19:76-84. 2013
    ..Additional study of FTD in diverse ethnic groups needs to address barriers to clinical presentation, including factors that may be culturally specific...
  26. pmc Nonfluent/agrammatic PPA with in-vivo cortical amyloidosis and Pick's disease pathology
    Francesca Caso
    Memory and Aging Center, University of California, San Francisco, CA 94143 1207, USA
    Behav Neurol 26:95-106. 2013
    ..This patient demonstrates that biomarkers indicating brain amyloidosis should not be considered conclusive evidence that AD pathology accounts for a typical FTD clinical/anatomical syndrome...
  27. pmc Clinical characterization of bvFTD due to FUS neuropathology
    Suzee E Lee
    University of California, San Francisco, Memory and Aging Center, San Francisco, CA 94143 1207, USA
    Neurocase 18:305-17. 2012
    ..This patient demonstrates the striking focality associated with FUS neuropathology in patients with bvFTD...
  28. pmc TDP-43 frontotemporal lobar degeneration and autoimmune disease
    Zachary A Miller
    UCSF Memory and Aging Center, University of California San Francisco, San Francisco, California 94143 1207, USA
    J Neurol Neurosurg Psychiatry 84:956-62. 2013
    ..Given the association between systemic inflammation and other neurodegenerative processes, links between autoimmunity and FTD need to be explored...
  29. pmc Role of right pregenual anterior cingulate cortex in self-conscious emotional reactivity
    Virginia E Sturm
    UCSF Department of Neurology, Memory and Aging Center, 350 Parnassus Avenue, Suite 905, Box 1207, San Francisco, California 94143 1207, USA
    Soc Cogn Affect Neurosci 8:468-74. 2013
    ....
  30. pmc Double dissociation in the anatomy of socioemotional disinhibition and executive functioning in dementia
    Casey E Krueger
    Memory and Aging Center, Department of Neurology, University of California, San Francisco, USA
    Neuropsychology 25:249-59. 2011
    ....
  31. pmc White matter damage in primary progressive aphasias: a diffusion tensor tractography study
    Sebastiano Galantucci
    Memory and Ageing Centre, Department of Neurology, University of California, San Francisco, San Francisco, CA 94143 1207, USA
    Brain 134:3011-29. 2011
    ..These results highlight the potential value of diffusion tensor imaging as a new tool in the multimodal diagnostic evaluation of primary progressive aphasia...
  32. ncbi request reprint Patterns of brain atrophy that differentiate corticobasal degeneration syndrome from progressive supranuclear palsy
    Adam L Boxer
    Memory and Aging Center, Department of Neurology, University of California, San Francisco, CA 94143 1207, USA
    Arch Neurol 63:81-6. 2006
    ..Progressive brain atrophy is associated with the corticobasal degeneration syndrome (CBDS) and progressive supranuclear palsy (PSP). Regional differences in brain atrophy may reflect the clinical features of disease...
  33. pmc Dissociations in hippocampal and frontal contributions to episodic memory performance
    Joel H Kramer
    Department of Neurology, University of California, San Francisco Medical Center, San Francisco, CA 94143, USA
    Neuropsychology 19:799-805. 2005
    ....
  34. pmc Visual search patterns in semantic dementia show paradoxical facilitation of binding processes
    Indre V Viskontas
    Memory and Aging Center, Department of Neurology, University of California, San Francisco, 350 Parnassus Ave, Ste 905, San Francisco, CA 94143, USA
    Neuropsychologia 49:468-78. 2011
    ....
  35. pmc The frontal-anatomic specificity of design fluency repetitions and their diagnostic relevance for behavioral variant frontotemporal dementia
    Katherine L Possin
    Department of Neurology, University of California, San Francisco, San Francisco, California 94143 1207, USA
    J Int Neuropsychol Soc 18:834-44. 2012
    ..These results highlight the frontal-anatomic specificity of design fluency repetitions. In addition, the results indicate that the propensity to make these errors supports the diagnosis of bvFTD. (JINS, 2012, 18, 1-11)...
  36. pmc Behavioral variant frontotemporal dementia with corticobasal degeneration pathology: phenotypic comparison to bvFTD with Pick's disease
    Katherine P Rankin
    University of California San Francisco, San Francisco, CA, USA
    J Mol Neurosci 45:594-608. 2011
    ..Despite a remarkable overlap between the two patient types, bvFTD patients with underlying CBD pathology show subtle clinical features that may distinguish them from patients with Pick's disease neuropathology...
  37. pmc Apolipoprotein E epsilon4 is associated with disease-specific effects on brain atrophy in Alzheimer's disease and frontotemporal dementia
    Federica Agosta
    Memory and Aging Center, Department of Neurology, University of California, 350 Parnassus Avenue, Suite 905, San Francisco, CA 94143, USA
    Proc Natl Acad Sci U S A 106:2018-22. 2009
    ..The atrophy patterns in epsilon4 carriers may indicate that they are at greater risk for clinical progression...
  38. pmc Rivastigmine is associated with restoration of left frontal brain activity in Parkinson's disease
    Katherine L Possin
    University of California, San Francisco, Department of Neurology, San Francisco, California, USA
    Mov Disord 28:1384-90. 2013
    ..PD patients with cognitive impairment show numerous regions of decreased spontaneous brain function compared with controls, and rivastigmine is associated with performance-related normalization in the left frontal cortex function...
  39. pmc Intrinsic connectivity networks in healthy subjects explain clinical variability in Alzheimer's disease
    Manja Lehmann
    Memory and Aging Center, Department of Neurology, University of California, San Francisco, CA 94158, USA
    Proc Natl Acad Sci U S A 110:11606-11. 2013
    ..Our findings indicate that the posterior DMN and precuneus network are commonly affected in AD variants, whereas syndrome-specific neurodegenerative patterns are driven by the involvement of specific networks outside the DMN. ..
  40. pmc Predicting regional neurodegeneration from the healthy brain functional connectome
    Juan Zhou
    Memory and Aging Center, Department of Neurology, University of California, San Francisco, San Francisco, CA 94143, USA
    Neuron 73:1216-27. 2012
    ..Molecular pathological approaches may help clarify what makes each epicenter vulnerable to its targeting disease and how toxic protein species travel between networked brain structures...
  41. pmc Abeta amyloid and glucose metabolism in three variants of primary progressive aphasia
    Gil D Rabinovici
    Memory and Aging Center, University of California San Francisco, San Francisco, CA 94143, USA
    Ann Neurol 64:388-401. 2008
    ....
  42. pmc Patterns of white matter atrophy in frontotemporal lobar degeneration
    Linda L Chao
    Center for Imaging of Neurodegenerative Diseases, San Francisco Department of Veterans Affairs Medical Center, San Francisco, CA 94121, USA
    Arch Neurol 64:1619-24. 2007
    ..Structural magnetic resonance imaging (MRI) has been used to investigate the in vivo pathology of frontotemporal lobar degeneration. However, few neuroimaging studies have focused on white matter (WM) alterations in this disease...
  43. pmc C-reactive protein is related to memory and medial temporal brain volume in older adults
    Brianne Magouirk Bettcher
    Department of Neurology, University of California, San Francisco, Memory and Aging Center, San Francisco, CA, USA
    Brain Behav Immun 26:103-8. 2012
    ..These findings underscore a potential role for inflammation in cognitive aging as a modifiable risk factor...
  44. pmc Neuropsychological, behavioral, and anatomical evolution in right temporal variant frontotemporal dementia: a longitudinal and post-mortem single case analysis
    Maya L Henry
    a Memory and Aging Center, Department of Neurology, University of California San Francisco, San Francisco, CA, USA
    Neurocase 20:100-9. 2014
    ..Findings support the view that left and right anterior temporal lobes serve as semantic hubs that may be affected differentially in semantic variant by early, relatively unilateral damage. ..
  45. pmc Intrinsic connectivity network disruption in progressive supranuclear palsy
    Raquel C Gardner
    Memory and Aging Center, Department of Neurology, University of California, San Francisco, San Francisco, CA, USA
    Ann Neurol 73:603-16. 2013
    ..Progressive supranuclear palsy (PSP) has been conceptualized as a large-scale network disruption, but the specific network targeted has not been fully characterized. We sought to delineate the affected network in patients with clinical PSP...
  46. pmc Neural basis of interpersonal traits in neurodegenerative diseases
    Marc Sollberger
    Memory and Aging Center, Department of Neurology, University of California, San Francisco, CA 94143 1207, USA
    Neuropsychologia 47:2812-27. 2009
    ..In addition, these findings indicate that interpersonal traits are subserved by complex neural networks rather than discrete anatomic areas...
  47. pmc Selective frontoinsular von Economo neuron and fork cell loss in early behavioral variant frontotemporal dementia
    Eun Joo Kim
    Memory and Aging Center, University of California, San Francisco, San Francisco, CA 94143, USA
    Cereb Cortex 22:251-9. 2012
    ..Right-sided VEN and fork cell losses, however, correlated with each other and with anatomical, functional, and behavioral severity. This work identifies region-specific neuronal targets in early bvFTD...
  48. pmc Diverging patterns of amyloid deposition and hypometabolism in clinical variants of probable Alzheimer's disease
    Manja Lehmann
    UCSF Memory and Ageing Centre, Department of Neurology, Box 1207, San Francisco, CA 94158 1207, USA
    Brain 136:844-58. 2013
    ....
  49. pmc Patterns of brain atrophy in clinical variants of frontotemporal lobar degeneration
    Po H Lu
    Department of Neurology, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA
    Dement Geriatr Cogn Disord 35:34-50. 2013
    ..Using magnetic resonance imaging (MRI), tensor-based morphometry (TBM) was used to determine distinct patterns of atrophy between these three clinical groups...
  50. pmc Sporadic corticobasal syndrome due to FTLD-TDP
    Maria Carmela Tartaglia
    Memory and Aging Center, Department of Neurology, University of California, 1207, 350 Parnassus Ave, Ste 905, San Francisco, CA 94143 1207, USA
    Acta Neuropathol 119:365-74. 2010
    ..These findings confirm that FTLD-TDP should be included in the pathological differential diagnosis for sporadic CBS...
  51. pmc Neuroanatomical correlates of cognitive self-appraisal in neurodegenerative disease
    Howard J Rosen
    Department of Neurology, University of California at San Francisco, San Francisco, CA, USA
    Neuroimage 49:3358-64. 2010
    ..We hypothesize that emotional/physiological processing carried out by vmPFC is an important factor mediating self-appraisal accuracy in dementia...
  52. pmc ASL perfusion MRI predicts cognitive decline and conversion from MCI to dementia
    Linda L Chao
    Center for Imaging of Neurodegenerative Disease, San Francisco, CA, USA
    Alzheimer Dis Assoc Disord 24:19-27. 2010
    ..03). These results suggest that hypoperfusion as detected by ASL-MRI can predict subsequent clinical, functional, and cognitive decline and may be useful for identifying candidates for future Alzheimer disease treatment trials...
  53. pmc Cognitive and behavioral challenges in caring for patients with frontotemporal dementia and amyotrophic lateral sclerosis
    Jennifer Merrilees
    University of California, San Francisco, USA
    Amyotroph Lateral Scler 11:298-302. 2010
    ..This paper provides a guide for healthcare providers caring for patients with FTD-ALS exhibiting behavioral, cognitive, and emotional symptoms. Strategies are suggested to help minimize the impact of negative symptoms...
  54. pmc Concordance and discordance between brain perfusion and atrophy in frontotemporal dementia
    Soichiro Shimizu
    Center for Imaging of Neurodegenerative Diseases, Veterans Affairs Medical Center, Department of Radiology and Biomedical Imaging, University of California, San Francisco, 4150 Clement Street, 114M, San Francisco, CA 94121, USA
    Brain Imaging Behav 4:46-54. 2010
    ..Detection of discordance between brain perfusion and structure in FTD might aid diagnosis and staging of the disease...
  55. pmc MRI patterns of atrophy and hypoperfusion associations across brain regions in frontotemporal dementia
    Duygu Tosun
    Center for Imaging Neurodegenerative Diseases, Veterans Affairs Medical Center, San Francisco, CA 94121, USA
    Neuroimage 59:2098-109. 2012
    ....
  56. pmc Clinicopathological correlations in corticobasal degeneration
    Suzee E Lee
    Memory and Aging Center, University of California San Francisco, San Francisco, CA 94143, USA
    Ann Neurol 70:327-40. 2011
    ..To characterize cognitive and behavioral features, physical findings, and brain atrophy patterns in pathology-proven corticobasal degeneration (CBD) and corticobasal syndrome (CBS) with known histopathology...
  57. pmc Patterns of cerebral hypoperfusion in amnestic and dysexecutive MCI
    Linda L Chao
    Center for Imaging of Neurodegenerative Diseases, San Francisco VA Medical Center, 4150 Clement Street, San Francisco, CA 94121, USA
    Alzheimer Dis Assoc Disord 23:245-52. 2009
    ..These data further suggest that cognitive impairment in MCI is related to cerebral hypoperfusion...
  58. pmc Magnetic resonance imaging correlates of set shifting
    Joel H Kramer
    Department of Neurology, University of California San Francisco, San Francisco, CA 94143, USA
    J Int Neuropsychol Soc 13:386-92. 2007
    ..Follow-up analyses indicated that frontal contributions to shifting were not related to working memory. Results highlight the importance of carefully controlling for component cognitive processes when studying executive functioning...
  59. pmc A case-controlled study of altered visual art production in Alzheimer's and FTLD
    Katherine P Rankin
    University of California, San Francisco, CA, USA
    Cogn Behav Neurol 20:48-61. 2007
    ..To characterize dementia-induced changes in visual art production...
  60. pmc Multiple cognitive deficits in amnestic mild cognitive impairment
    Joel H Kramer
    San Francisco Medical Center, University of California, San Francisco, CA 94143, USA
    Dement Geriatr Cogn Disord 22:306-11. 2006
    ..To determine if more widespread cognitive deficits are present in a narrowly defined group of patients with the amnestic form of mild cognitive impairment (MCI)...
  61. pmc Seizures and epileptiform activity in the early stages of Alzheimer disease
    Keith A Vossel
    Gladstone Institute of Neurological Disease, San Francisco, California2Memory and Aging Center, Department of Neurology, University of California, San Francisco, California
    JAMA Neurol 70:1158-66. 2013
    ..We report key features of AD-related seizures and epileptiform activity that are instructive for clinical practice and highlight similarities between AD and transgenic animal models of the disease...
  62. pmc Plasma acetylcholinesterase activity correlates with intracerebral β-amyloid load
    Adi Alkalay
    Helen Wills Neuroscience Institute, University of California Berkeley, CA, USA
    Curr Alzheimer Res 10:48-56. 2013
    ..We examined the relationship between amyloid-beta (Aβ) plaques and plasma cholinesterase activity in a heterogeneous dementia population...
  63. pmc MRI signatures of brain macrostructural atrophy and microstructural degradation in frontotemporal lobar degeneration subtypes
    Yu Zhang
    Department of Veterans Affairs Medical Center, Center for Imaging of Neurodegenerative Diseases, San Francisco, CA 94121, USA
    J Alzheimers Dis 33:431-44. 2013
    ..The findings suggest that DTI in general and radial diffusivity in particular are more powerful measures for the classification of FTLD patients from controls than brain atrophy...
  64. pmc Detecting sarcasm from paralinguistic cues: anatomic and cognitive correlates in neurodegenerative disease
    Katherine P Rankin
    Memory and Aging Center, University of California San Francisco, Department of Neurology, San Francisco, CA 94143 1207, USA
    Neuroimage 47:2005-15. 2009
    ....
  65. pmc Executive functions and the down-regulation and up-regulation of emotion
    Anett Gyurak
    Departments of Psychiatry and Psychology, Stanford University, San Francisco, CA, USA
    Cogn Emot 26:103-18. 2012
    ..These findings contribute to our understanding of emotion-cognition interaction, suggesting a link between emotion-regulatory abilities and individual differences in complex executive functions...
  66. pmc Increased metabolic vulnerability in early-onset Alzheimer's disease is not related to amyloid burden
    Gil D Rabinovici
    Memory and Aging Center, University of California San Francisco, San Francisco, CA 94143, USA
    Brain 133:512-28. 2010
    ..Our data are consistent with a model in which both early amyloid-beta accumulation and increased vulnerability to amyloid-beta pathology play critical roles in the pathogenesis of Alzheimer's disease in young patients...
  67. pmc Connected speech production in three variants of primary progressive aphasia
    Stephen M Wilson
    Memory and Aging Center, Department of Neurology, University of California, San Francisco, 350 Parnassus Avenue, Suite 905, San Francisco, CA 94143, USA
    Brain 133:2069-88. 2010
    ....
  68. pmc Neuroanatomical correlates of behavioural disorders in dementia
    Howard J Rosen
    Department of Neurology, Memory and Aging Center, University of California, San Francisco, CA 94143 1207, USA
    Brain 128:2612-25. 2005
    ..Furthermore, the findings underscore the utility of studying patients with dementia for understanding the neuroanatomical basis of social and emotional functions...
  69. pmc Identifying cognitively healthy elderly individuals with subsequent memory decline by using automated MR temporoparietal volumes
    Gloria C Chiang
    Department of Radiology, University of California, San Francisco, 505 Parnassus Ave, Room M391, San Francisco, CA, 94143, USA
    Radiology 259:844-51. 2011
    ..To determine whether automated temporoparietal brain volumes can be used to accurately predict future memory decline among a multicenter cohort of cognitively healthy elderly individuals...
  70. pmc A tensor based morphometry study of longitudinal gray matter contraction in FTD
    Simona M Brambati
    Memory and Aging Center, UCSF Department of Neurology, 350 Parnassus Ave, Suite 706, San Francisco, CA 94143, USA
    Neuroimage 35:998-1003. 2007
    ..These results suggest that TBM might be useful in tracking progression of regional atrophy in FTD...
  71. ncbi request reprint Anatomical correlates of sentence comprehension and verbal working memory in neurodegenerative disease
    Serena Amici
    Memory and Aging Center, Department of Neurology, University of California, San Francisco, San Francisco, California 94143 1207, USA
    J Neurosci 27:6282-90. 2007
    ..This study reconciles two opposing views, which hold that sentence comprehension and vWM rely on either the same or different anatomical resources...
  72. pmc Clinical, cognitive and anatomical evolution from nonfluent progressive aphasia to corticobasal syndrome: a case report
    Maria Luisa Gorno-Tempini
    Department of Neurology, University of California San Francisco, San Francisco, CA 94143 1207, USA
    Neurocase 10:426-36. 2004
    ..This case demonstrates the clinical overlap between FTLD and CBS and shows that the two can appear in the same patient at different stages of the disease in relation to the progression of anatomical damage...
  73. pmc Progranulin mutations as risk factors for Alzheimer disease
    David C Perry
    Department of Neurology, University of California, San Francisco, CA 94158, USA
    JAMA Neurol 70:774-8. 2013
    ..We describe 2 patients with progranulin gene mutations and evidence of Alzheimer disease (AD) pathology. We also conducted a literature review...
  74. ncbi request reprint Challenging the clinical utility of the 14-3-3 protein for the diagnosis of sporadic Creutzfeldt-Jakob disease
    Michael D Geschwind
    Department of Neurology, University of California, San Francisco Medical Center, San Francisco, CA 94143, USA
    Arch Neurol 60:813-6. 2003
    ..Previous studies have suggested that, in the proper clinical context, the 14-3-3 protein in cerebrospinal fluid is a reliable marker for sporadic CJD...
  75. ncbi request reprint Portraits of artists: emergence of visual creativity in dementia
    Bruce L Miller
    Department of Neurology, University of California, San Francisco, CA 94143, USA
    Arch Neurol 61:842-4. 2004
    ..Art in the context of dementia provides a unique window into the cognitive processes of various brain regions and an opportunity for rehabilitation...
  76. ncbi request reprint Sporadic Pick's disease: a tauopathy characterized by a spectrum of pathological tau isoforms in gray and white matter
    Victoria Zhukareva
    Department of Pathology and Laboratory Medicine, Center for Neurodegenerative Disease Research, University of Pennsylvania, 3600 Spruce Street, Philadelphia, PA 19104 4283, USA
    Ann Neurol 51:730-9. 2002
    ....
  77. ncbi request reprint Frontotemporal dementia: genetics and genetic counseling dilemmas
    Jill S Goldman
    Memory and Aging Center, University of California, San Francisco, Department of Neurology, San Francisco, California 94143 1207, USA
    Neurologist 10:227-34. 2004
    ..The objective of this paper is to enable physicians to recognize hereditary patterns and genetic concerns of FTD families and to understand genetic counseling strategies...
  78. ncbi request reprint White matter lesions are associated with cortical atrophy more than entorhinal and hippocampal atrophy
    An Tao Du
    Magnetic Resonance Unit 114M, Department of Veterans Affairs Medical Center, 4150, Clement Street, San Francisco, CA 94121, USA
    Neurobiol Aging 26:553-9. 2005
    ..Further, AD pathology and subcortical vascular disease may independently affect cortical atrophy...
  79. ncbi request reprint Patterns of cognitive and emotional empathy in frontotemporal lobar degeneration
    Katherine P Rankin
    Memory and Aging Center, University of California San Francisco, California 94145 1203, USA
    Cogn Behav Neurol 18:28-36. 2005
    ..To examine the relationship between empathy and cognition in frontotemporal lobar degeneration (FTLD)...
  80. ncbi request reprint Patterns of cerebral atrophy in primary progressive aphasia
    Howard J Rosen
    Department of Neurology, Memory and Aging Center, University of California at San Francisco, CA 94143 1207, USA
    Am J Geriatr Psychiatry 10:89-97. 2002
    ..Different clinical syndromes in PPA are associated with different patterns of atrophy. In the future, combined analysis of imaging and clinical characteristics may allow more accurate etiologic diagnosis...
  81. ncbi request reprint Stereotypical movements and frontotemporal dementia
    Mario F Mendez
    Department of Neurology, University of California at Los Angeles, 11301 Wilshire Boulevard, Los Angeles, CA 90073, USA
    Mov Disord 20:742-5. 2005
    ....
  82. ncbi request reprint When sporadic disease is not sporadic: the potential for genetic etiology
    Jill S Goldman
    University of California, Memory and Aging Center, San Francisco 94143 1207, USA
    Arch Neurol 61:213-6. 2004
    ..Approximately 2% of Alzheimer disease cases and 10% to 15% of prion disease cases are due to mutations in autosomal dominant genes. Mutations have been found in patients without family histories of neurological disease...
  83. ncbi request reprint Non-Alzheimer's disease dementias: anatomic, clinical, and molecular correlates
    Craig E Hou
    Department of Neurology, University of California at San Francisco, USA
    Can J Psychiatry 49:164-71. 2004
    ..We also discuss the pharmacologic treatment of these disorders...
  84. ncbi request reprint A neurocomputational model of analogical reasoning and its breakdown in frontotemporal lobar degeneration
    Robert G Morrison
    Department of Psychology, University of California, Los Angelesm 90095 1563, USA
    J Cogn Neurosci 16:260-71. 2004
    ..Using the "Learning and Inference with Schemas and Analogies" model, we provide a specific account of how such deficits may arise within neural networks supporting analogical problem solving...
  85. ncbi request reprint Relationship between positive and negative symptoms and neuropsychological scores in frontotemporal dementia and Alzheimer's disease
    Kyle Brauer Boone
    Department of Psychiatry, Harbor UCLA Medical Center, Torrance, California 90509, USA
    J Int Neuropsychol Soc 9:698-709. 2003
    ..These findings add to the existing literature relating negative symptoms to anterior cerebral hypofunction, and suggest that positive symptoms, at least in this population, may be tied to increased posterior activation...
  86. ncbi request reprint Art and the brain: the influence of frontotemporal dementia on an accomplished artist
    Joshua Chang Mell
    Genetics Graduate Group, University of California at Davis, USA
    Neurology 60:1707-10. 2003
    ..The study of artistic development in the setting of FTD suggests that language is not required for, and may even inhibit, certain types of visual creativity...
  87. ncbi request reprint Sporadic Creutzfeldt-Jakob disease mimicking variant Creutzfeldt-Jakob disease
    Jennifer Martindale
    Department of Neurology, University of California San Francisco, 94143, USA
    Arch Neurol 60:767-70. 2003
    ..The determination of the form of prion disease and early diagnosis are important for prognostic, public health, and epidemiologic reasons...
  88. ncbi request reprint Distinctive neuropsychological patterns in frontotemporal dementia, semantic dementia, and Alzheimer disease
    Joel H Kramer
    University of California Medical Center, San Francisco, California 94143, USA
    Cogn Behav Neurol 16:211-8. 2003
    ..To assess the ability of a brief neuropsychological bedside screening battery to discriminate between Alzheimer disease, frontotemporal dementia, and semantic dementia...
  89. ncbi request reprint Relational integration and executive function in Alzheimer's disease
    James A Waltz
    Departjment of Psychology, University of California, Los Angeles, CA 90095 1563, USA
    Neuropsychology 18:296-305. 2004
    ....
  90. pmc Double dissociation of social functioning in frontotemporal dementia
    Katherine P Rankin
    University of California San Francisco, USA
    Neurology 60:266-71. 2003
    ..Efforts to characterize changes in social functioning in frontotemporal dementia (FTD) have failed to elicit clear dissociation between frontal and temporal variants of the disease based on behavioral measures...
  91. pmc Cognition and anatomy in three variants of primary progressive aphasia
    Maria Luisa Gorno-Tempini
    Department of Neurology, UCSF Memory and Aging Center, University of California San Francisco, 350 Parnassus Avenue, San Francisco, CA 94143, USA
    Ann Neurol 55:335-46. 2004
    ..Cognitive, genetic, and anatomical features indicate that different PPA clinical variants may correspond to different underlying pathological processes...
  92. ncbi request reprint 17q-linked frontotemporal dementia-amyotrophic lateral sclerosis without tau mutations with tau and alpha-synuclein inclusions
    Kirk C Wilhelmsen
    Ernest Gallo Clinic and Research Center, Emeryville, CA, USA
    Arch Neurol 61:398-406. 2004
    ..The most common familial form of this condition is caused by mutations in the microtubule-associated protein tau gene (MAP tau) and is associated with neuronal or glial tau inclusions...
  93. ncbi request reprint Laboratory investigations and treatment in frontotemporal dementia
    Florence Pasquier
    CHRU Clinique Neurologie, Lille France
    Ann Neurol 54:S32-5. 2003
  94. ncbi request reprint Very early-onset familial Alzheimer's disease: a novel presenilin 1 mutation
    Jill S Goldman
    UCSF Memory and Aging Center, San Francisco, CA 94143, USA
    Int J Geriatr Psychiatry 17:649-51. 2002
    ..Early-onset familial Alzheimer's disease (EOFAD) is linked to mutations in three autosomal dominant genes: PS1, PS2 and APP. The clinical presentation and age of onset of mutations is variable...
  95. ncbi request reprint Frontotemporal lobar degeneration: demographic characteristics of 353 patients
    Julene K Johnson
    Department of Neurology, Memory and Aging Center, University of California, San Francisco, 94117, USA
    Arch Neurol 62:925-30. 2005
    ..The publication of consensus criteria for FTLD, however, prompted systematic studies. The criteria categorize FTLD into 3 subgroups: frontotemporal dementia, semantic dementia, and progressive nonfluent aphasia...
  96. ncbi request reprint Acquired sociopathy and frontotemporal dementia
    Mario F Mendez
    Department of Neurology and Psychiatry, University of California at Los Angeles, USA
    Dement Geriatr Cogn Disord 20:99-104. 2005
    ..It is not understood why some patients with frontotemporal dementia (FTD) manifest sociopathic behavior...
  97. ncbi request reprint Continuum of frontal lobe impairment in amyotrophic lateral sclerosis
    Jennifer M Murphy
    Department of Neurology, ALS Center, University of California, San Francisco, CA 94117, USA
    Arch Neurol 64:530-4. 2007
    ..To identify the nature and prevalence of cognitive and behavioral abnormalities in patients with amyotrophic lateral sclerosis (ALS)...
  98. pmc Association of GSK3B with Alzheimer disease and frontotemporal dementia
    Barbara A J Schaffer
    Department of Neurology, David Geffen School of Medicine, University of California, Los Angeles, 2506 Gonda, 695 Charles E Young Dr S, Los Angeles, CA 90095 1761, USA
    Arch Neurol 65:1368-74. 2008
    ..As a known tau kinase, GSK3B is a promising candidate gene in the remaining cases of FTD and in AD, for which tau mutations have not been found...
  99. pmc Gene expression study on peripheral blood identifies progranulin mutations
    Giovanni Coppola
    Department of Neurology, Program in Neurogenetics, David Geffen School of Medicine, University of California at Los Angeles, Los Angeles, CA 90095, USA
    Ann Neurol 64:92-6. 2008
    ..This proof-of-principle report supports the use of gene quantification as diagnostic screen for PGRN mutations and suggests a potential role for progranulin in Alzheimer's disease...
  100. pmc Concomitant TAR-DNA-binding protein 43 pathology is present in Alzheimer disease and corticobasal degeneration but not in other tauopathies
    Kunihiro Uryu
    Center for Neurodegenerative Disease Research, Department of Pathology and Laboratory Medicine, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA
    J Neuropathol Exp Neurol 67:555-64. 2008
    ..These findings provide further insight into the burden and clinical significance of TDP-43 pathology in disorders other than FTLD-U and amyotrophic lateral sclerosis...
  101. doi request reprint Distraction during relational reasoning: the role of prefrontal cortex in interference control
    Daniel C Krawczyk
    Center for BrainHealth, The University of Texas at Dallas, Dallas, TX 75235, USA
    Neuropsychologia 46:2020-32. 2008
    ..These results demonstrate that intact prefrontal cortex (PFC) is necessary for controlling interference from perceptual and semantic distractors in order to reason from relational structure...