Ian Meng

Summary

Affiliation: University of New England
Country: USA

Publications

  1. pmc The role of corneal afferent neurons in regulating tears under normal and dry eye conditions
    Ian D Meng
    Department of Biomedical Sciences, College of Osteopathic Medicine, University of New England, 11 Hills Beach Rd, Biddeford, ME 04005, USA Electronic address
    Exp Eye Res 117:79-87. 2013
  2. pmc Corneal dry-responsive neurons in the spinal trigeminal nucleus respond to innocuous cooling in the rat
    Masayuki Kurose
    Division of Oral Physiology, Department of Oral Biological Sciences, Niigata University, Graduate School of Medical and Dental Sciences, Niigata, Japan
    J Neurophysiol 109:2517-22. 2013
  3. pmc Chronic morphine exposure increases the proportion of on-cells in the rostral ventromedial medulla in rats
    Ian D Meng
    Department of Physiology, College of Osteopathic Medicine, University of New England, 11 Hills Beach Rd Biddeford, ME 04005, USA
    Life Sci 80:1915-20. 2007
  4. ncbi request reprint Antinociception and modulation of rostral ventromedial medulla neuronal activity by local microinfusion of a cannabinoid receptor agonist
    I D Meng
    Department of Neurology, University of California, San Francisco, CA 94143 0114, USA
    Neuroscience 124:685-93. 2004
  5. ncbi request reprint Kappa opioids inhibit physiologically identified medullary pain modulating neurons and reduce morphine antinociception
    I D Meng
    Department of Neurology, University of California, San Francisco, California, USA
    J Neurophysiol 93:1138-44. 2005
  6. ncbi request reprint An analgesia circuit activated by cannabinoids
    I D Meng
    Department of Neurology, W M Keck Foundation Center for Integrative Neuroscience, University of California, San Francisco 94143 0114, USA
    Nature 395:381-3. 1998
  7. ncbi request reprint The cannabinoid receptor agonist, WIN 55,212-2, inhibits cool-specific lamina I medullary dorsal horn neurons
    A Ogawa
    Department of Physiology, College of Osteopathic Medicine, University of New England, Biddeford, ME 04005, USA
    Neuroscience 143:265-72. 2006
  8. ncbi request reprint Local application of the cannabinoid receptor agonist, WIN 55,212-2, to spinal trigeminal nucleus caudalis differentially affects nociceptive and non-nociceptive neurons
    Alex M Papanastassiou
    Department of Neurology, University of California, San Francisco, CA 94143 0114, USA
    Pain 107:267-75. 2004
  9. ncbi request reprint Differential responses of rostral subnucleus caudalis and upper cervical dorsal horn neurons to mechanical and chemical stimulation of the parotid gland in rats
    Akiko Ogawa
    Department of Oral Diagnosis, School of Dentistry, Nihon University, Kanda Surugadai, Chiyoda ku, Tokyo 101 8310, Japan
    Brain Res 1106:123-33. 2006
  10. ncbi request reprint From migraine to chronic daily headache: the biological basis of headache transformation
    Ian D Meng
    Department of Physiology, University of New England College of Osteopathic Medicine, Biddeford, ME 04005, USA
    Headache 47:1251-8. 2007

Collaborators

Detail Information

Publications11

  1. pmc The role of corneal afferent neurons in regulating tears under normal and dry eye conditions
    Ian D Meng
    Department of Biomedical Sciences, College of Osteopathic Medicine, University of New England, 11 Hills Beach Rd, Biddeford, ME 04005, USA Electronic address
    Exp Eye Res 117:79-87. 2013
    ..Furthermore, the dry eye condition itself may modify the properties of corneal afferents and affect their ability to regulate secretion, a possibility just now being explored. ..
  2. pmc Corneal dry-responsive neurons in the spinal trigeminal nucleus respond to innocuous cooling in the rat
    Masayuki Kurose
    Division of Oral Physiology, Department of Oral Biological Sciences, Niigata University, Graduate School of Medical and Dental Sciences, Niigata, Japan
    J Neurophysiol 109:2517-22. 2013
    ....
  3. pmc Chronic morphine exposure increases the proportion of on-cells in the rostral ventromedial medulla in rats
    Ian D Meng
    Department of Physiology, College of Osteopathic Medicine, University of New England, 11 Hills Beach Rd Biddeford, ME 04005, USA
    Life Sci 80:1915-20. 2007
    ....
  4. ncbi request reprint Antinociception and modulation of rostral ventromedial medulla neuronal activity by local microinfusion of a cannabinoid receptor agonist
    I D Meng
    Department of Neurology, University of California, San Francisco, CA 94143 0114, USA
    Neuroscience 124:685-93. 2004
    ..These results indicate that cannabinoids act directly within the RVM to affect off-cell activity, providing one mechanism by which cannabinoids produce antinociception...
  5. ncbi request reprint Kappa opioids inhibit physiologically identified medullary pain modulating neurons and reduce morphine antinociception
    I D Meng
    Department of Neurology, University of California, San Francisco, California, USA
    J Neurophysiol 93:1138-44. 2005
    ....
  6. ncbi request reprint An analgesia circuit activated by cannabinoids
    I D Meng
    Department of Neurology, W M Keck Foundation Center for Integrative Neuroscience, University of California, San Francisco 94143 0114, USA
    Nature 395:381-3. 1998
    ..These results show that analgesia produced by cannabinoids and opioids involves similar brainstem circuitry and that cannabinoids are indeed centrally acting analgesics with a new mechanism of action...
  7. ncbi request reprint The cannabinoid receptor agonist, WIN 55,212-2, inhibits cool-specific lamina I medullary dorsal horn neurons
    A Ogawa
    Department of Physiology, College of Osteopathic Medicine, University of New England, Biddeford, ME 04005, USA
    Neuroscience 143:265-72. 2006
    ..These results demonstrate a potential mechanism by which cannabinoids produce hypothermia, and also suggest that cannabinoids may affect non-noxious thermal discrimination...
  8. ncbi request reprint Local application of the cannabinoid receptor agonist, WIN 55,212-2, to spinal trigeminal nucleus caudalis differentially affects nociceptive and non-nociceptive neurons
    Alex M Papanastassiou
    Department of Neurology, University of California, San Francisco, CA 94143 0114, USA
    Pain 107:267-75. 2004
    ..Furthermore, the particular sensitivity of PDC activity, a measure of neuronal hyperexcitability, to cannabinoid receptor agonists may be relevant to the treatment of persistent craniofacial pain...
  9. ncbi request reprint Differential responses of rostral subnucleus caudalis and upper cervical dorsal horn neurons to mechanical and chemical stimulation of the parotid gland in rats
    Akiko Ogawa
    Department of Oral Diagnosis, School of Dentistry, Nihon University, Kanda Surugadai, Chiyoda ku, Tokyo 101 8310, Japan
    Brain Res 1106:123-33. 2006
    ..The present data indicate that the hyperalgesia and referred pain associated with parotitis may result from sensitization of C1/C2, but not Vi/Vc nociceptive neurons...
  10. ncbi request reprint From migraine to chronic daily headache: the biological basis of headache transformation
    Ian D Meng
    Department of Physiology, University of New England College of Osteopathic Medicine, Biddeford, ME 04005, USA
    Headache 47:1251-8. 2007
    ....
  11. ncbi request reprint Mustard oils and cannabinoids excite sensory nerve fibres through the TRP channel ANKTM1
    Sven Eric Jordt
    Department of Cellular and Molecular Pharmacology University of California, San Francisco, California 94143 2140, USA
    Nature 427:260-5. 2004
    ..These findings identify a cellular and molecular target for the pungent action of mustard oils and support an emerging role for TRP channels as ionotropic cannabinoid receptors...

Research Grants2

  1. Trigeminal Mechanisms of Cannabinoid Analgesia
    Ian Meng; Fiscal Year: 2005
    ..abstract_text> ..
  2. Chronic morphine-induced sensitization of trigeminal dura sensitive neurons
    Ian D Meng; Fiscal Year: 2010
    ..Understanding the neuro-adaptive changes that occur with chronic morphine exposure will lead the way to new therapeutic strategies to treat headache patients while reducing the risk of developing MOH. ..