JAMES MENEGAZZI

Summary

Affiliation: University of Pittsburgh
Country: USA

Publications

  1. pmc Post-resuscitation hemodynamics and relationship to the duration of ventricular fibrillation
    James J Menegazzi
    Department of Emergency Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA
    Resuscitation 78:355-8. 2008
  2. ncbi request reprint Overcoming ACLS dogma: how quickly should we change?
    James J Menegazzi
    Prehosp Emerg Care 7:410-3. 2003
  3. doi request reprint Derivation of clinical predictors of failed rescue shock during out-of-hospital ventricular fibrillation
    James J Menegazzi
    Department of Emergency Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15213, USA
    Prehosp Emerg Care 12:347-51. 2008
  4. pmc The effect of ischemia on ventricular fibrillation as measured by fractal dimension and frequency measures
    Lawrence D Sherman
    St Francis Hospital, Federal Way, WA, USA
    Resuscitation 75:499-505. 2007
  5. ncbi request reprint Effects of an impedance threshold device on hemodynamics and restoration of spontaneous circulation in prolonged porcine ventricular fibrillation
    James J Menegazzi
    Department of Emergency Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA
    Prehosp Emerg Care 11:179-85. 2007
  6. pmc Drug administration in animal studies of cardiac arrest does not reflect human clinical experience
    Joshua C Reynolds
    School of Medicine, University of Pittsburgh, Pittsburgh, PA 15213, United States
    Resuscitation 74:13-26. 2007
  7. ncbi request reprint Association of delay to first intervention with return of spontaneous circulation in a swine model of cardiac arrest
    Jon C Rittenberger
    University of Pittsburgh, Department of Emergency Medicine, Pittsburgh, PA 15213, USA
    Resuscitation 73:154-60. 2007
  8. ncbi request reprint Adenosine A1 receptor antagonism hastens the decay in ventricular fibrillation waveform morphology during porcine cardiac arrest
    Timothy J Mader
    The Department of Emergency Medicine, Baystate Medical Center Tufts University School of Medicine, 759 Chestnut Street, Springfield, MA 01199, United States
    Resuscitation 71:254-9. 2006
  9. doi request reprint The effect of adenosine A1 receptor antagonism on return of spontaneous circulation and short-term survival in prolonged ventricular fibrillation
    Timothy J Mader
    Department of Emergency Medicine, Baystate Medical Center Tufts University School of Medicine, Boston, Massachusetts, USA
    Prehosp Emerg Care 12:352-8. 2008
  10. ncbi request reprint A randomized comparison of manual, mechanical and high-impulse chest compression in a porcine model of prolonged ventricular fibrillation
    Amy E Betz
    Department of Emergency Medicine, University of Pittsburgh School of Medicine, 230 McKee Place, Suite 400, Pittsburgh, PA 15213, USA
    Resuscitation 69:495-501. 2006

Research Grants

  1. Derivation of Innovative Treatments for Cardiac Death
    JAMES MENEGAZZI; Fiscal Year: 2005
  2. Physiology of Prolonged Ventricular Fibrillation
    JAMES MENEGAZZI; Fiscal Year: 2008

Collaborators

Detail Information

Publications19

  1. pmc Post-resuscitation hemodynamics and relationship to the duration of ventricular fibrillation
    James J Menegazzi
    Department of Emergency Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA
    Resuscitation 78:355-8. 2008
    ..We sought to characterize the time-course of these patterns, and to determine whether these differed based on duration of the VF insult...
  2. ncbi request reprint Overcoming ACLS dogma: how quickly should we change?
    James J Menegazzi
    Prehosp Emerg Care 7:410-3. 2003
    ..At the end of the year 2000 there was insufficient evidence to recommend any other approach than shock as soon as possible and perform CPR at all other times...
  3. doi request reprint Derivation of clinical predictors of failed rescue shock during out-of-hospital ventricular fibrillation
    James J Menegazzi
    Department of Emergency Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15213, USA
    Prehosp Emerg Care 12:347-51. 2008
    ..Failed rescue shocks have been shown to decrease the likelihood of survival in the treatment of out-of-hospital ventricular fibrillation (VF). Avoidance of failed shocks may improve survival...
  4. pmc The effect of ischemia on ventricular fibrillation as measured by fractal dimension and frequency measures
    Lawrence D Sherman
    St Francis Hospital, Federal Way, WA, USA
    Resuscitation 75:499-505. 2007
    ..The scaling exponent (ScE), the logarithm of the absolute correlations (LAC) and the Hurst exponent (HE) are three measures of the fractal dimension of VF...
  5. ncbi request reprint Effects of an impedance threshold device on hemodynamics and restoration of spontaneous circulation in prolonged porcine ventricular fibrillation
    James J Menegazzi
    Department of Emergency Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA
    Prehosp Emerg Care 11:179-85. 2007
    ..An impedance threshold device (ITD) has been designed to enhance circulation during CPR by creating a negative intrathoracic pressure during the relaxation phase of chest compression...
  6. pmc Drug administration in animal studies of cardiac arrest does not reflect human clinical experience
    Joshua C Reynolds
    School of Medicine, University of Pittsburgh, Pittsburgh, PA 15213, United States
    Resuscitation 74:13-26. 2007
    ..Our previous work has shown the mean time to first drug administration in clinical trials is 19.4min. We hypothesized that the average time to drug administration in large animal experiments occurs earlier than in OOHCA clinical trials...
  7. ncbi request reprint Association of delay to first intervention with return of spontaneous circulation in a swine model of cardiac arrest
    Jon C Rittenberger
    University of Pittsburgh, Department of Emergency Medicine, Pittsburgh, PA 15213, USA
    Resuscitation 73:154-60. 2007
    ..We sought to determine the duration of circulatory arrest after which maximal drug treatment and a rescue shock would fail to achieve return of spontaneous circulation (ROSC)...
  8. ncbi request reprint Adenosine A1 receptor antagonism hastens the decay in ventricular fibrillation waveform morphology during porcine cardiac arrest
    Timothy J Mader
    The Department of Emergency Medicine, Baystate Medical Center Tufts University School of Medicine, 759 Chestnut Street, Springfield, MA 01199, United States
    Resuscitation 71:254-9. 2006
    ..The objective of this study was to determine the effect of ADO receptor antagonism, as measured by the scaling exponent (ScE), on the degeneration of VF over time during the circulatory phase of cardiac arrest...
  9. doi request reprint The effect of adenosine A1 receptor antagonism on return of spontaneous circulation and short-term survival in prolonged ventricular fibrillation
    Timothy J Mader
    Department of Emergency Medicine, Baystate Medical Center Tufts University School of Medicine, Boston, Massachusetts, USA
    Prehosp Emerg Care 12:352-8. 2008
    ..We have previously shown that ADO A1 receptor (ADOA1R) antagonism hastens the time-dependent decay in VF waveform morphology during the circulatory phase of cardiac arrest...
  10. ncbi request reprint A randomized comparison of manual, mechanical and high-impulse chest compression in a porcine model of prolonged ventricular fibrillation
    Amy E Betz
    Department of Emergency Medicine, University of Pittsburgh School of Medicine, 230 McKee Place, Suite 400, Pittsburgh, PA 15213, USA
    Resuscitation 69:495-501. 2006
    ..We hypothesized that HI (very rapid acceleration of the down-stroke) would produce greater CPPs than MAN or MECH, and that HI would also produce a higher rate of ROSC...
  11. ncbi request reprint Dynamic nature of electrocardiographic waveform predicts rescue shock outcome in porcine ventricular fibrillation
    Christopher B Lightfoot
    Department of Emergency Medicine, Center for Emergency Medicine of Western Pennsylvania, University of Pittsburgh, Pittsburgh, PA 15213, USA
    Ann Emerg Med 42:230-41. 2003
    ..This study examined whether the scaling exponent could predict rescue shock success and whether unsuccessful rescue shocks altered the structure of the ventricular fibrillation waveform and the responsiveness to subsequent rescue shocks...
  12. ncbi request reprint Immediate defibrillation versus interventions first in a swine model of prolonged ventricular fibrillation
    James J Menegazzi
    Department of Emergency Medicine, 230 McKee Place, Suite 400, Pittsburgh, PA 15213, USA
    Resuscitation 59:261-70. 2003
    ..We also sought to determine the predictive value of the ScE in determining post-shock outcomes...
  13. ncbi request reprint Ventricular fibrillation scaling exponent can guide timing of defibrillation and other therapies
    James J Menegazzi
    Department of Emergency Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA
    Circulation 109:926-31. 2004
    ..The scaling exponent (ScE) of the ventricular fibrillation (VF) waveform correlates with duration of VF and predicts defibrillation outcome. We compared 4 therapeutic approaches to the treatment of VF of various durations...
  14. ncbi request reprint Angular velocity: a new method to improve prediction of ventricular fibrillation duration
    Lawrence D Sherman
    Department of Emergency Medicine, University of Pittsburg School of Medicine, Pittsburgh, PA 15213, USA
    Resuscitation 60:79-90. 2004
    ..The combination of ScE and AV can be used in developing strategies for the treatment of VF during the different clinical phases of VF...
  15. ncbi request reprint Waveform analysis of ventricular fibrillation to predict defibrillation
    Clifton W Callaway
    University of Pittsburgh, School of Medicine, Pittsburgh, Pennsylvania 15213, USA
    Curr Opin Crit Care 11:192-9. 2005
    ..Quantitative analysis of the ventricular fibrillation waveform may distinguish coarse ventricular fibrillation from fine ventricular fibrillation, allowing more appropriate delivery of rescue shocks...
  16. doi request reprint Use of prehospital-induced hypothermia after out-of-hospital cardiac arrest: a survey of the National Association of Emergency Medical Services Physicians
    Brian P Suffoletto
    Department of Emergency Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15213, USA
    Prehosp Emerg Care 12:52-6. 2008
    ..We sought to determine the prevalence of EMS agencies that use prehospital IH. We also sought to determine what perceived barriers to initiating IH might exist and the understanding EMS physicians have of guidelines for IH...
  17. ncbi request reprint Why isn't hypothermia after cardiac arrest the standard of care?
    James J Menegazzi
    Prehosp Emerg Care 9:475-6. 2005
  18. ncbi request reprint A randomized, controlled comparison of cardiopulmonary resuscitation performed on the floor and on a moving ambulance stretcher
    John A Kim
    Affiliated Residency in Emergency Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA
    Prehosp Emerg Care 10:68-70. 2006
    ..Recent studies have demonstrated that cardiopulmonary resuscitation (CPR) of poor quality is associated with worsened outcomes...
  19. ncbi request reprint Time to give the first medication during resuscitation in out-of-hospital cardiac arrest
    Jon C Rittenberger
    Department of Emergency Medicine, University of Pittsburgh, Pittsburgh, PA 15213, USA
    Resuscitation 70:201-6. 2006
    ..Then, the mean time and ranges of reported study medication delivery in clinical trials where medication was the experimental intervention was determined...

Research Grants2

  1. Derivation of Innovative Treatments for Cardiac Death
    JAMES MENEGAZZI; Fiscal Year: 2005
    ..We will determine whether changes in the recommended sequence of resuscitation interventions can be ustified in certain clinical situations, and which should receive future prospective study. ..
  2. Physiology of Prolonged Ventricular Fibrillation
    JAMES MENEGAZZI; Fiscal Year: 2008
    ..These studies are novel because they will use a recently discovered, clinically available indicator (the ScE) in a model that will also allow examination of resuscitation outcomes. ..