Jacek Mamczarz

Summary

Affiliation: University of Maryland
Country: USA

Publications

  1. doi request reprint Galantamine counteracts development of learning impairment in guinea pigs exposed to the organophosphorus poison soman: clinical significance
    Jacek Mamczarz
    Division of Translational Toxicology, Department Epidemiology and Public Health, University of Maryland School of Medicine, 10 S Pine St Suite 900, Baltimore, MD 21210, USA
    Neurotoxicology 32:785-98. 2011
  2. pmc Delayed hippocampal effects from a single exposure of prepubertal guinea pigs to sub-lethal dose of chlorpyrifos: a magnetic resonance imaging and spectroscopy study
    Roger J Mullins
    Department of Diagnostic Radiology and Nuclear Medicine, University of Maryland School of Medicine, Baltimore, MD 21201, United States
    Neurotoxicology 36:42-8. 2013
  3. pmc Prenatal exposure of guinea pigs to the organophosphorus pesticide chlorpyrifos disrupts the structural and functional integrity of the brain
    Roger J Mullins
    Department of Diagnostic Radiology and Nuclear Medicine, University of Maryland School of Medicine, Baltimore, MD 21201, United States Program in Neuroscience, University of Maryland School of Medicine, Baltimore, MD 21201, United States
    Neurotoxicology 48:9-20. 2015
  4. doi request reprint An acute exposure to a sub-lethal dose of soman triggers anxiety-related behavior in guinea pigs: interactions with acute restraint
    Jacek Mamczarz
    Department of Pharmacology and Experimental Therapeutics, University of Maryland School of Medicine, Baltimore, MD 21201, USA
    Neurotoxicology 31:77-84. 2010
  5. ncbi request reprint Preclinical investigation of the topical administration of phenserine: transdermal flux, cholinesterase inhibition, and cognitive efficacy
    Tadanobu Utsuki
    Drug Design and Development Section, Laboratory of Neurosciences, National Institute on Aging, National Institutes of Health, Baltimore, Maryland, USA
    J Pharmacol Exp Ther 321:353-61. 2007

Collaborators

  • Edson X Albuquerque
  • Su Xu
  • Nigel H Greig
  • Roger J Mullins
  • Rao P Gullapalli
  • Edna F R Pereira
  • Tadanobu Utsuki
  • Spencer W Todd
  • Joseph D Pescrille
  • Tetsumi Irie
  • Edward L Spangler
  • Nao Uchimura
  • Harold W Holloway
  • Qian sheng Yu
  • Hiroshi Moriuchi
  • Mitsuru Irikura
  • Donald K Ingram

Detail Information

Publications5

  1. doi request reprint Galantamine counteracts development of learning impairment in guinea pigs exposed to the organophosphorus poison soman: clinical significance
    Jacek Mamczarz
    Division of Translational Toxicology, Department Epidemiology and Public Health, University of Maryland School of Medicine, 10 S Pine St Suite 900, Baltimore, MD 21210, USA
    Neurotoxicology 32:785-98. 2011
    ..In conclusion, learning impairment develops months after a single exposure to 1xLD50 soman, and galantamine prevents both the acute toxicity and the delayed cognitive deficits triggered by this OP poison...
  2. pmc Delayed hippocampal effects from a single exposure of prepubertal guinea pigs to sub-lethal dose of chlorpyrifos: a magnetic resonance imaging and spectroscopy study
    Roger J Mullins
    Department of Diagnostic Radiology and Nuclear Medicine, University of Maryland School of Medicine, Baltimore, MD 21201, United States
    Neurotoxicology 36:42-8. 2013
    ....
  3. pmc Prenatal exposure of guinea pigs to the organophosphorus pesticide chlorpyrifos disrupts the structural and functional integrity of the brain
    Roger J Mullins
    Department of Diagnostic Radiology and Nuclear Medicine, University of Maryland School of Medicine, Baltimore, MD 21201, United States Program in Neuroscience, University of Maryland School of Medicine, Baltimore, MD 21201, United States
    Neurotoxicology 48:9-20. 2015
    ..These findings reveal the lasting effect of prenatal exposure to CPF as well as the danger of mother to child transmission of CPF in the environment...
  4. doi request reprint An acute exposure to a sub-lethal dose of soman triggers anxiety-related behavior in guinea pigs: interactions with acute restraint
    Jacek Mamczarz
    Department of Pharmacology and Experimental Therapeutics, University of Maryland School of Medicine, Baltimore, MD 21201, USA
    Neurotoxicology 31:77-84. 2010
    ..It is concluded that a single exposure to sub-lethal doses of soman triggers long-lasting anxiogenesis and decreased locomotor activity and that acute restraint stress modifies the magnitude of these effects...
  5. ncbi request reprint Preclinical investigation of the topical administration of phenserine: transdermal flux, cholinesterase inhibition, and cognitive efficacy
    Tadanobu Utsuki
    Drug Design and Development Section, Laboratory of Neurosciences, National Institute on Aging, National Institutes of Health, Baltimore, Maryland, USA
    J Pharmacol Exp Ther 321:353-61. 2007
    ..Particular benefits over oral therapies might include avoiding first-pass metabolic effects and improved dosing compliance...