R Scott Mackin

Summary

Affiliation: University of California
Country: USA

Publications

  1. pmc Association of age at depression onset with cognitive functioning in individuals with late-life depression and executive dysfunction
    R Scott Mackin
    Department of Psychiatry, University of California, San Francisco, San Francisco, CA Center for Imaging of Neurodegenerative Disease, Veterans Administration Medical Center, San Francisco, CA Electronic address
    Am J Geriatr Psychiatry 22:1633-41. 2014
  2. pmc Cognitive outcomes after psychotherapeutic interventions for major depression in older adults with executive dysfunction
    R Scott Mackin
    Department of Psychiatry, University of California, San Francisco, San Francisco, CA Center for Imaging of Neurodegenerative Disease, San Francisco, CA Veterans Administration Medical Center, San Francisco, CA Electronic address
    Am J Geriatr Psychiatry 22:1496-503. 2014
  3. pmc Problem solving therapy for the treatment of depression for a patient with Parkinson's disease and mild cognitive impairment: a case study
    R Scott Mackin
    Department of Psychiatry, University of California, San Francisco, CA, USA
    Neuropsychiatr Dis Treat 2:375-9. 2006
  4. doi request reprint The effect of subsyndromal symptoms of depression and white matter lesions on disability for individuals with mild cognitive impairment
    R Scott Mackin
    Center for Imaging of Neurodegenerative Diseases, Veterans Administration Medical Center, San Francisco, CA Department of Psychiatry, University of California, San Francisco, CA Electronic address
    Am J Geriatr Psychiatry 21:906-14. 2013
  5. pmc Patterns of reduced cortical thickness in late-life depression and relationship to psychotherapeutic response
    R Scott Mackin
    Center for Imaging of Neurodegenerative Diseases, Veterans Administration Medical Center, University of California, San Francisco, CA Department of Psychiatry, University of California, San Francisco, CA Electronic address
    Am J Geriatr Psychiatry 21:794-802. 2013
  6. pmc Longitudinal stability of subsyndromal symptoms of depression in individuals with mild cognitive impairment: relationship to conversion to dementia after 3 years
    R Scott Mackin
    Department of Psychiatry, University of California, San Francisco, CA, USA
    Int J Geriatr Psychiatry 27:355-63. 2012
  7. pmc Pattern of cognitive impairment in older veterans with posttraumatic stress disorder evaluated at a memory disorders clinic
    R Scott Mackin
    Department of Psychiatry, University of California, San Francisco, CA, USA
    Int J Geriatr Psychiatry 27:637-42. 2012
  8. pmc Cognitive functioning in individuals with severe compulsive hoarding behaviors and late life depression
    R Scott Mackin
    Department of Psychiatry, University of California, San Francisco, USA
    Int J Geriatr Psychiatry 26:314-21. 2011
  9. pmc The effect of cognitive impairment on mental healthcare costs for individuals with severe psychiatric illness
    R Scott Mackin
    Department of Psychiatry, University of California, San Francisco, CA 94143 0984, USA
    Am J Geriatr Psychiatry 19:176-84. 2011
  10. ncbi request reprint Evidence-based psychotherapeutic interventions for geriatric depression
    R Scott Mackin
    Department of Psychiatry and Langley Porter Psychiatric Institute, University of California San Francisco, 401 Parnassus Avenue, Box F 0984, San Francisco, CA 94143 0984, USA
    Psychiatr Clin North Am 28:805-20, vii-viii. 2005

Collaborators

Detail Information

Publications29

  1. pmc Association of age at depression onset with cognitive functioning in individuals with late-life depression and executive dysfunction
    R Scott Mackin
    Department of Psychiatry, University of California, San Francisco, San Francisco, CA Center for Imaging of Neurodegenerative Disease, Veterans Administration Medical Center, San Francisco, CA Electronic address
    Am J Geriatr Psychiatry 22:1633-41. 2014
    ..To compare patterns of cognitive performance in older adults with late-onset depression (LOD; ≥65 years of age) with that of older adults with early-onset depression (EOD; <65 years)...
  2. pmc Cognitive outcomes after psychotherapeutic interventions for major depression in older adults with executive dysfunction
    R Scott Mackin
    Department of Psychiatry, University of California, San Francisco, San Francisco, CA Center for Imaging of Neurodegenerative Disease, San Francisco, CA Veterans Administration Medical Center, San Francisco, CA Electronic address
    Am J Geriatr Psychiatry 22:1496-503. 2014
    ..The purpose of this study was to determine the impact of psychotherapy on cognitive functioning in older adults with late-life depression (LLD) and executive dysfunction...
  3. pmc Problem solving therapy for the treatment of depression for a patient with Parkinson's disease and mild cognitive impairment: a case study
    R Scott Mackin
    Department of Psychiatry, University of California, San Francisco, CA, USA
    Neuropsychiatr Dis Treat 2:375-9. 2006
    ..These results suggest that PST may be an effective treatment for the treatment of depression for individuals with a PD and concurrent MCI...
  4. doi request reprint The effect of subsyndromal symptoms of depression and white matter lesions on disability for individuals with mild cognitive impairment
    R Scott Mackin
    Center for Imaging of Neurodegenerative Diseases, Veterans Administration Medical Center, San Francisco, CA Department of Psychiatry, University of California, San Francisco, CA Electronic address
    Am J Geriatr Psychiatry 21:906-14. 2013
    ..To assess the effect of subsyndromal symptoms of depression (SSD) on ratings of disability for individuals with mild cognitive impairment (MCI)...
  5. pmc Patterns of reduced cortical thickness in late-life depression and relationship to psychotherapeutic response
    R Scott Mackin
    Center for Imaging of Neurodegenerative Diseases, Veterans Administration Medical Center, University of California, San Francisco, CA Department of Psychiatry, University of California, San Francisco, CA Electronic address
    Am J Geriatr Psychiatry 21:794-802. 2013
    ..This study was conducted to evaluate patterns of cortical thickness in LLD and in relation to psychotherapy treatment outcomes...
  6. pmc Longitudinal stability of subsyndromal symptoms of depression in individuals with mild cognitive impairment: relationship to conversion to dementia after 3 years
    R Scott Mackin
    Department of Psychiatry, University of California, San Francisco, CA, USA
    Int J Geriatr Psychiatry 27:355-63. 2012
    ..To evaluate the degree to which longitudinal stability of subsyndromal symptoms of depression (SSD) is associated with conversion to dementia in patients with mild cognitive impairment (MCI)...
  7. pmc Pattern of cognitive impairment in older veterans with posttraumatic stress disorder evaluated at a memory disorders clinic
    R Scott Mackin
    Department of Psychiatry, University of California, San Francisco, CA, USA
    Int J Geriatr Psychiatry 27:637-42. 2012
    ..We determined the pattern of clinically significant cognitive impairment (CI) among older veterans with posttraumatic stress disorder (PTSD) evaluated in a memory disorders clinic...
  8. pmc Cognitive functioning in individuals with severe compulsive hoarding behaviors and late life depression
    R Scott Mackin
    Department of Psychiatry, University of California, San Francisco, USA
    Int J Geriatr Psychiatry 26:314-21. 2011
    ....
  9. pmc The effect of cognitive impairment on mental healthcare costs for individuals with severe psychiatric illness
    R Scott Mackin
    Department of Psychiatry, University of California, San Francisco, CA 94143 0984, USA
    Am J Geriatr Psychiatry 19:176-84. 2011
    ..This study was conducted to determine the effect of cognitive impairment (CI) on mental healthcare costs for older low-income adults with severe psychiatric illness...
  10. ncbi request reprint Evidence-based psychotherapeutic interventions for geriatric depression
    R Scott Mackin
    Department of Psychiatry and Langley Porter Psychiatric Institute, University of California San Francisco, 401 Parnassus Avenue, Box F 0984, San Francisco, CA 94143 0984, USA
    Psychiatr Clin North Am 28:805-20, vii-viii. 2005
  11. pmc The sensitivity and specificity of cognitive screening instruments to detect cognitive impairment in older adults with severe psychiatric illness
    R Scott Mackin
    Department of Psychiatry and Langley Porter Psychiatric Institute, University of California, San Francisco, San Francisco, CA 94143, USA
    J Geriatr Psychiatry Neurol 23:94-9. 2010
    ..Brief cognitive screening instruments are frequently used to evaluate cognitive functioning in CMHCs, but the validity of these measures for detecting CI has not been adequately evaluated in this patient population...
  12. ncbi request reprint Cognitive and psychiatric predictors of medical treatment adherence among older adults in primary care clinics
    R Scott Mackin
    Department of Psychiatry, University of California, San Francisco, CA 94143 0984, USA
    Int J Geriatr Psychiatry 22:55-60. 2007
    ..Treatment non-adherence has been associated with a number of factors in older adults; however few studies have delineated the role of cognition and psychiatric status...
  13. doi request reprint Impaired financial capacity in late life depression is associated with cognitive performance on measures of executive functioning and attention
    R Scott Mackin
    Department of Psychiatry and Langley Porter Psychiatric Institute, University of California, San Francisco, San Francisco, California 94143 0984, USA
    J Int Neuropsychol Soc 15:793-8. 2009
    ..Our results suggest impairments of financial capacity in LLD are largely explained by cognitive functioning in these domains...
  14. pmc Incidence and documentation of cognitive impairment among older adults with severe mental illness in a community mental health setting
    R Scott Mackin
    Department of Psychiatry, University of California, San Francisco, CA, USA
    Am J Geriatr Psychiatry 17:75-82. 2009
    ..Few studies have explored the incidence and documentation of cognitive impairments in this patient population...
  15. pmc Problem-solving therapy and supportive therapy in older adults with major depression and executive dysfunction: effect on disability
    George S Alexopoulos
    Department of Psychiatry, Weill Cornell Medical College, White Plains, NY 10605, USA
    Arch Gen Psychiatry 68:33-41. 2011
    ..Older patients with depression and executive dysfunction represent a population with significant disability and a high likelihood of failing pharmacotherapy...
  16. pmc Different associations of white matter lesions with depression and cognition
    Jun Young Lee
    Center for Imaging of Neurodegenerative Diseases, Veterans Affairs Medical Center, San Francisco, CA 94121, USA
    BMC Neurol 12:83. 2012
    ....
  17. pmc Problem-solving therapy and supportive therapy in older adults with major depression and executive dysfunction
    Patricia A Arean
    Department of Psychiatry, University of California, San Francisco, CA 94143, USA
    Am J Psychiatry 167:1391-8. 2010
    ..The purpose of this study was to determine whether problem-solving therapy is an effective treatment in older patients with depression and executive dysfunction, a population likely to be resistant to antidepressant drugs...
  18. pmc Accelerating rates of cognitive decline and imaging markers associated with β-amyloid pathology
    Philip S Insel
    From the Center for Imaging of Neurodegenerative Diseases P S I, R S M, R L N, D T, M W W, Department of Veterans Affairs Medical Center, San Francisco Departments of Radiology and Biomedical Imaging P S I, D T, M W W and Psychiatry R S M, University of California, San Francisco Clinical Memory Research Unit, Faculty of Medicine P S I, N M, Lund University Memory Clinic N M and Department of Neurology N M, Skane University Hospital, Lund University MedTech West and the Department of Clinical Neuroscience and Rehabilitation M S, University of Gothenburg, Sweden Department of Neurology M C D, P S A, Keck School of Medicine, University of Southern California, Los Angeles Helen Wills Neuroscience Institute W J J, University of California, Berkeley and Life Sciences Division M S, W J J, Lawrence Berkeley National Laboratory, Berkeley CA
    Neurology 86:1887-96. 2016
    ..To estimate points along the spectrum of β-amyloid pathology at which rates of change of several measures of neuronal injury and cognitive decline begin to accelerate...
  19. pmc Chronic Depressive Symptomatology in Mild Cognitive Impairment Is Associated with Frontal Atrophy Rate which Hastens Conversion to Alzheimer Dementia
    Simona Sacuiu
    Center for Imaging of Neurodegenerative Diseases, Veterans Affairs Medical Center, San Francisco, CA Department of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, CA Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Sweden
    Am J Geriatr Psychiatry 24:126-35. 2016
    ..Investigate the association of chronic depressive symptomatology (chrDS) with cortical atrophy rates and conversion to Alzheimer dementia (AD) over 3 years in mild cognitive impairment (MCI)...
  20. doi request reprint Cognitive and functional changes associated with Aβ pathology and the progression to mild cognitive impairment
    Philip S Insel
    Clinical Memory Research Unit, Faculty of Medicine, Lund University, Lund, Sweden Center for Imaging of Neurodegenerative Diseases, Department of Veterans Affairs Medical Center, San Francisco, CA, USA Department of Radiology and Biomedical Imaging, University of California, San Francisco, CA, USA Electronic address
    Neurobiol Aging 48:172-181. 2016
    ..Composites incorporating both cognitive and functional measures may substantially increase the power of a trial in a preclinical (Aβ+) AD population with subtle evidence of cognitive dysfunction...
  21. pmc Assessing risk for preclinical β-amyloid pathology with APOE, cognitive, and demographic information
    Philip S Insel
    Clinical Memory Research Unit, Faculty of Medicine, Lund University, Lund, Sweden Center for Imaging of Neurodegenerative Diseases, Department of Veterans Affairs Medical Center, San Francisco, CA, USA Department of Radiology and Biomedical Imaging, University of California, San Francisco, CA, USA
    Alzheimers Dement (Amst) 4:76-84. 2016
    ..This study's objective was to evaluate the extent to which inexpensive and easily obtainable information can reduce the number of screen failures by increasing the proportion of Aβ+ participants identified for screening...
  22. pmc Patterns of alcohol and drug use among depressed older adults seeking outpatient psychiatric services
    Derek D Satre
    Department of Psychiatry, University of California, San Francisco, 94143, USA
    Am J Geriatr Psychiatry 19:695-703. 2011
    ....
  23. pmc The transitional association between β-amyloid pathology and regional brain atrophy
    Philip S Insel
    Department of Veterans Affairs Medical Center, Center for Imaging of Neurodegenerative Diseases, San Francisco, CA, USA Electronic address
    Alzheimers Dement 11:1171-9. 2015
    ..To determine the relationship between Aβ and atrophy, we compared the performance of the usual dichotomization of cerebrospinal fluid (CSF) Aβ to identify subjects as Aβ+ and Aβ- with a trilinear spline model of CSF Aβ...
  24. pmc Neuroimaging abnormalities in adults with sickle cell anemia: associations with cognition
    R Scott Mackin
    From the Department of Psychiatry R S M, University of California, San Francisco Center for Imaging of Neurodegenerative Diseases R S M, P I, D T, J B, M W W, San Francisco Veterans Administration Medical Center, San Francisco Hematology Oncology Department E P V, L D N, Children s Hospital and Research Center Oakland Keck School of Medicine J I G, University of Southern California Departments of Anesthesiology and Pediatrics J I G, Children s Hospital Los Angeles, CA Rho, Inc K K, Research Triangle Park, NC Department of Pediatrics F D A, University of Miami Miller School of Medicine and Holtz Children s Hospital, Miami, FL and Veterans Administration Medical Center M W W, and Departments of Radiology, Medicine, Psychiatry, and Neurology, University of California, San Francisco
    Neurology 82:835-41. 2014
    ..This study was conducted to determine the relationship of frontal lobe cortical thickness and basal ganglia volumes to measures of cognition in adults with sickle cell anemia (SCA)...
  25. doi request reprint PATTERNS OF CLINICALLY SIGNIFICANT COGNITIVE IMPAIRMENT IN HOARDING DISORDER
    R Scott Mackin
    Department of Psychiatry, University of California, San Francisco, California
    Depress Anxiety 33:211-8. 2016
    ..However, there have been no studies evaluating the degree to which cognitive dysfunction in these domains reflects clinically significant cognitive impairment (CI)...
  26. doi request reprint Comparison of a peer facilitated support group to cognitive behavior therapy: Study protocol for a randomized controlled trial for hoarding disorder
    Soo Y Uhm
    Department of Psychiatry, University of California, San Francisco, California, USA
    Contemp Clin Trials 50:98-105. 2016
    ..Secondary outcomes include reduction in other indices of hoarding symptomology, including functional impairment, physical clutter, cognition, and changes in neuropsychological functioning. ..
  27. pmc Neuropsychological and dimensional behavioral trait profiles in Costa Rican ADHD sib pairs: Potential intermediate phenotypes for genetic studies
    Viviana A Peskin
    Department of Psychiatry, University of California, San Francisco, San Francisco, California
    Am J Med Genet B Neuropsychiatr Genet 168:247-57. 2015
    ..The use of multigenerational families from a genetically isolated population may facilitate the identification of ADHD risk genes in the face of phenotypic and genetic heterogeneity...
  28. pmc Cerebrospinal fluid α-synuclein and Lewy body-like symptoms in normal controls, mild cognitive impairment, and Alzheimer's disease
    R Scott Mackin
    Department of Veterans Affairs Medical Center, Center for Imaging of Neurodegenerative Diseases, San Francisco, CA, USA Department of Psychiatry, University of California, San Francisco, CA, USA
    J Alzheimers Dis 43:1007-16. 2015
    ..Co-occurrence of Lewy body pathology is common in Alzheimer's disease (AD) patients, but it is unknown if reduced CSF α-synuclein is associated with Lewy body-like symptomatology in AD...
  29. ncbi request reprint Relationship of the Wender Utah Rating Scale to objective measures of attention
    R Scott Mackin
    Department of Psychiatry, University of California, San Francisco, 94143 0984, USA
    Compr Psychiatry 46:468-71. 2005
    ..59, P < .01). Thus, poor performance on a sensitive, but nonspecific, measure of attention with executive function, response speed, and visuomotor coordination components was related to greater self-report of childhood ADHD symptoms...