J P Lynch

Summary

Affiliation: University of Michigan
Country: USA

Publications

  1. ncbi request reprint Usual interstitial pneumonia
    J P Lynch
    Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, University of Michigan Medical Center, Ann Arbor, Michigan 48109 0360, USA
    Semin Respir Crit Care Med 22:357-86. 2001
  2. ncbi request reprint Computed tomographic scanning in sarcoidosis
    Joseph P Lynch
    Division of Pulmonary and Critical Care Medicine, University of Michigan Medical Center, Ann Arbor, Michigan 48109 0360, USA
    Semin Respir Crit Care Med 24:393-418. 2003
  3. ncbi request reprint Hospital-acquired pneumonia: risk factors, microbiology, and treatment
    J P Lynch
    Division of Pulmonary and Critical Care Medicine, University of Michigan Medical Center, 3916 Tubman Center, Ann Arbor, MI 48109, USA
    Chest 119:373S-384S. 2001
  4. ncbi request reprint Corticosteroids in idiopathic pulmonary fibrosis
    J P Lynch
    Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, University of Michigan Medical Center, 3916 Taubman Center, Ann Arbor, MI 48109, USA
    Curr Opin Pulm Med 7:298-308. 2001
  5. ncbi request reprint Steroids in idiopathic pulmonary fibrosis: a prospective assessment of adverse reactions, response to therapy, and survival
    K R Flaherty
    Division of Pulmonary and Critical Care, University of Michigan Health System, Ann Arbor, Michigan 48109-0360, USA
    Am J Med 110:278-82. 2001
  6. ncbi request reprint Histopathologic variability in usual and nonspecific interstitial pneumonias
    K R Flaherty
    Department of Radiology, University of Michigan Health System, University of Michigan School of Public Health, Ann Arbor, Michigan 48109-0360, USA
    Am J Respir Crit Care Med 164:1722-7. 2001
  7. pmc Pulmonary hypertension associated with lung transplantation obliterative bronchiolitis and vascular remodeling of the allograft
    R Saggar
    Division of Pulmonary and Critical Care Medicine, Department of Medicine, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA
    Am J Transplant 8:1921-30. 2008
  8. pmc CXCR3 chemokine ligands during respiratory viral infections predict lung allograft dysfunction
    S S Weigt
    Division of Pulmonary and Critical Care Medicine, Department of Medicine, David Geffen School of Medicine, at UCLA, Los Angeles, CA, USA
    Am J Transplant 12:477-84. 2012
  9. ncbi request reprint ENA-78 is an important angiogenic factor in idiopathic pulmonary fibrosis
    M P Keane
    Division of Pulmonary and Critical Care Medicine, Department of Medicine, UCLA School of Medicine, Los Angeles, California 90095 1922, USA
    Am J Respir Crit Care Med 164:2239-42. 2001
  10. pmc Aspergillus colonization of the lung allograft is a risk factor for bronchiolitis obliterans syndrome
    S S Weigt
    Division of Pulmonary and Critical Care Medicine, Department of Medicine, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA
    Am J Transplant 9:1903-11. 2009

Collaborators

Detail Information

Publications17

  1. ncbi request reprint Usual interstitial pneumonia
    J P Lynch
    Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, University of Michigan Medical Center, Ann Arbor, Michigan 48109 0360, USA
    Semin Respir Crit Care Med 22:357-86. 2001
    ..In this article, we discuss diagnostic criteria for UIP (both histopathological and radiographic), natural history and clinical course, and therapeutic approaches (both current and future)...
  2. ncbi request reprint Computed tomographic scanning in sarcoidosis
    Joseph P Lynch
    Division of Pulmonary and Critical Care Medicine, University of Michigan Medical Center, Ann Arbor, Michigan 48109 0360, USA
    Semin Respir Crit Care Med 24:393-418. 2003
    ..This article discusses the salient HRCT features of sarcoidosis, accuracy of CT in the differential diagnosis, and correlations of HRCT with disease extent and activity, pulmonary function, and lesion reversibility...
  3. ncbi request reprint Hospital-acquired pneumonia: risk factors, microbiology, and treatment
    J P Lynch
    Division of Pulmonary and Critical Care Medicine, University of Michigan Medical Center, 3916 Tubman Center, Ann Arbor, MI 48109, USA
    Chest 119:373S-384S. 2001
    ..For pseudomonal HAP, we advise combination therapy with an antipseudomonal beta-lactam plus an aminoglycoside or a fluoroquinolone (eg, ciprofloxacin)...
  4. ncbi request reprint Corticosteroids in idiopathic pulmonary fibrosis
    J P Lynch
    Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, University of Michigan Medical Center, 3916 Taubman Center, Ann Arbor, MI 48109, USA
    Curr Opin Pulm Med 7:298-308. 2001
    ....
  5. ncbi request reprint Steroids in idiopathic pulmonary fibrosis: a prospective assessment of adverse reactions, response to therapy, and survival
    K R Flaherty
    Division of Pulmonary and Critical Care, University of Michigan Health System, Ann Arbor, Michigan 48109-0360, USA
    Am J Med 110:278-82. 2001
    ..Whether this difference reflects an effect of treatment or less severe disease can be determined only in a randomized trial...
  6. ncbi request reprint Histopathologic variability in usual and nonspecific interstitial pneumonias
    K R Flaherty
    Department of Radiology, University of Michigan Health System, University of Michigan School of Public Health, Ann Arbor, Michigan 48109-0360, USA
    Am J Respir Crit Care Med 164:1722-7. 2001
    ..001), although survival in the two UIP groups was comparable (p = 0.16). Lobar histologic variability is frequent in patients with IIP, patients with a histologic pattern of UIP in any lobe should be classified as having UIP...
  7. pmc Pulmonary hypertension associated with lung transplantation obliterative bronchiolitis and vascular remodeling of the allograft
    R Saggar
    Division of Pulmonary and Critical Care Medicine, Department of Medicine, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA
    Am J Transplant 8:1921-30. 2008
    ..4%, p < 0.0001, and 77% vs. 35%, p = 0.004, respectively). PH is common in LT recipients with pathologic OB/BOS and is associated with a vasculopathy of the allograft pulmonary circulation...
  8. pmc CXCR3 chemokine ligands during respiratory viral infections predict lung allograft dysfunction
    S S Weigt
    Division of Pulmonary and Critical Care Medicine, Department of Medicine, David Geffen School of Medicine, at UCLA, Los Angeles, CA, USA
    Am J Transplant 12:477-84. 2012
    ..CXCR3 chemokine concentrations provide prognostic information and this may have important implications for the development of novel treatment strategies to modify outcomes after CARV infection...
  9. ncbi request reprint ENA-78 is an important angiogenic factor in idiopathic pulmonary fibrosis
    M P Keane
    Division of Pulmonary and Critical Care Medicine, Department of Medicine, UCLA School of Medicine, Los Angeles, California 90095 1922, USA
    Am J Respir Crit Care Med 164:2239-42. 2001
    ..These findings support the notion that ENA-78 may be an important additional factor that regulates angiogenic activity in IPF...
  10. pmc Aspergillus colonization of the lung allograft is a risk factor for bronchiolitis obliterans syndrome
    S S Weigt
    Division of Pulmonary and Critical Care Medicine, Department of Medicine, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA
    Am J Transplant 9:1903-11. 2009
    ....
  11. ncbi request reprint Antimicrobial resistance in Streptococcus pneumoniae: implications for patients with community-acquired pneumonia
    C E Chenoweth
    Department of Internal Medicine, University of Michigan Health System, Ann Arbor 48109 0378, USA
    Mayo Clin Proc 75:1161-8. 2000
    ..In this article, we provide an overview of the development of S pneumoniae resistance to commonly used antibiotics and discuss the implications of the development of resistance on treatment decisions...
  12. ncbi request reprint Diagnosis of unilateral mainstem bronchial obstruction following single-lung transplantation with routine spirometry
    G R Neagos
    Division of Pulmonary and Critical Care Medicine, University of Michigan Medical Center, Ann Arbor 48109 0360
    Chest 103:1255-8. 1993
    ..This unique aberration in the flow-volume curve sheds new insight into the physiologic abnormalities of spirometry in patients receiving lung transplants...
  13. ncbi request reprint Lung mechanics and dyspnea after lung transplantation for chronic airflow obstruction
    F J Martinez
    Department of Internal Medicine, University of Michigan School of Medicine, Ann Arbor, USA
    Am J Respir Crit Care Med 153:1536-43. 1996
    ..EELV increases in SLT recipients at peak exercise, although overall aerobic response is preserved and respiratory sensation is similar...
  14. ncbi request reprint Pulmonary function tests in interstitial lung disease: what role do they have?
    E H Alhamad
    Division of Pulmonary and Critical Care Medicine, University of Michigan Medical Center, Ann Arbor, USA
    Clin Chest Med 22:715-50, ix. 2001
    ....
  15. pmc Critical role for the chemokine MCP-1/CCR2 in the pathogenesis of bronchiolitis obliterans syndrome
    J A Belperio
    Department of Medicine, Division of Pulmonary and Critical Care Medicine, University of California Los Angeles School of Medicine, Los Angeles, California 90024 1922, USA
    J Clin Invest 108:547-56. 2001
    ..Lymphocyte infiltration was not reduced under these conditions. We suggest that MCP-1/CCR2 signaling plays an important role in recruitment of mononuclear phagocytes, a pivotal event in the pathogenesis of BOS...
  16. ncbi request reprint Lymphoproliferative disease after lung transplantation: comparison of presentation and outcome of early and late cases
    S Paranjothi
    Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Washington University School of Medicine, St. Louis, Missouri 63110, USA
    J Heart Lung Transplant 20:1054-63. 2001
    ..PTLD that is confined to the allograft appears to have a somewhat better prognosis than disease that involves other sites...
  17. pmc Radiological versus histological diagnosis in UIP and NSIP: survival implications
    K R Flaherty
    Division of Pulmonary and Critical Care Medicine, University of Michigan Health System, Ann Arbor, MI, USA
    Thorax 58:143-8. 2003
    ..High resolution computed tomography (HRCT) has an important diagnostic role in idiopathic interstitial pneumonia (IIP). We hypothesised that the HRCT appearance would have an impact on survival in patients with IIP...