Yair Lotan

Summary

Affiliation: University of Texas Southwestern Medical Center
Country: USA

Publications

  1. ncbi request reprint Should we screen for bladder cancer in a high-risk population?: A cost per life-year saved analysis
    Yair Lotan
    Department of Urology, University of Texas Southwestern Medical Center, Dallas, Texas 75390 9110, USA
    Cancer 107:982-90. 2006
  2. doi request reprint Predictive value of combined immunohistochemical markers in patients with pT1 urothelial carcinoma at radical cystectomy
    Shahrokh F Shariat
    Department of Urology, University of Texas Southwestern Medical Center, Dallas, Texas, USA
    J Urol 182:78-84; discussion 84. 2009
  3. doi request reprint Predictive value of the differential expression of the urokinase plasminogen activation axis in radical prostatectomy patients
    Amit Gupta
    Department of Urology, University of Texas Southwestern Medical Center, Dallas, Texas 75390 9110, USA
    Eur Urol 55:1124-33. 2009
  4. doi request reprint Prospective evaluation of a molecular marker panel for prediction of recurrence and cancer-specific survival after radical cystectomy
    Yair Lotan
    Department of Urology, University of Texas Southwestern Medical Center Dallas, TX 75390, USA
    Eur Urol 64:465-71. 2013
  5. doi request reprint Predicting clinical outcomes after radical nephroureterectomy for upper tract urothelial carcinoma
    Eugene K Cha
    Department of Urology, Weill Cornell Medical College, New York Presbyterian Hospital, New York, NY 10065, USA
    Eur Urol 61:818-25. 2012
  6. doi request reprint Radical nephroureterectomy for pathologic T4 upper tract urothelial cancer: can oncologic outcomes be improved with multimodality therapy?
    Ramy F Youssef
    UT Southwestern Medical Center, Dallas, TX, USA
    Int Braz J Urol 39:614-21. 2013
  7. doi request reprint Oncological outcomes after radical nephroureterectomy for upper tract urothelial carcinoma: comparison over the three decades
    Mehrad Adibi
    Department of Urology, UT Southwestern Medical Center, Dallas, TX 75390 9110, USA
    Int J Urol 19:1060-6. 2012
  8. ncbi request reprint Outcomes of radical cystectomy for transitional cell carcinoma of the bladder: a contemporary series from the Bladder Cancer Research Consortium
    Shahrokh F Shariat
    Department of Urology, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390, USA
    J Urol 176:2414-22; discussion 2422. 2006
  9. doi request reprint Impact of smoking and smoking cessation on outcomes in bladder cancer patients treated with radical cystectomy
    Michael Rink
    Department of Urology, Weill Cornell Medical College, New York Presbyterian Hospital, New York, NY 10065, USA
    Eur Urol 64:456-64. 2013
  10. ncbi request reprint Concomitant carcinoma in situ is a feature of aggressive disease in patients with organ-confined TCC at radical cystectomy
    Shahrokh F Shariat
    Department of Urology, University of Texas Southwestern Medical Center, Dallas, TX 75390 9110, USA
    Eur Urol 51:152-60. 2007

Collaborators

Detail Information

Publications131 found, 100 shown here

  1. ncbi request reprint Should we screen for bladder cancer in a high-risk population?: A cost per life-year saved analysis
    Yair Lotan
    Department of Urology, University of Texas Southwestern Medical Center, Dallas, Texas 75390 9110, USA
    Cancer 107:982-90. 2006
    ..The U.S. Food and Drug Administration recently approved screening high-risk patients for bladder cancer using urine-based markers. The cost and life-years saved associated with bladder cancer screening were evaluated...
  2. doi request reprint Predictive value of combined immunohistochemical markers in patients with pT1 urothelial carcinoma at radical cystectomy
    Shahrokh F Shariat
    Department of Urology, University of Texas Southwestern Medical Center, Dallas, Texas, USA
    J Urol 182:78-84; discussion 84. 2009
    ..We tested whether the combination of immunohistochemical markers could risk stratify cases of pT1 urothelial carcinoma of the bladder at radical cystectomy...
  3. doi request reprint Predictive value of the differential expression of the urokinase plasminogen activation axis in radical prostatectomy patients
    Amit Gupta
    Department of Urology, University of Texas Southwestern Medical Center, Dallas, Texas 75390 9110, USA
    Eur Urol 55:1124-33. 2009
    ..This axis is involved in cell proliferation, angiogenesis, extracellular matrix degradation, invasion, and metastases...
  4. doi request reprint Prospective evaluation of a molecular marker panel for prediction of recurrence and cancer-specific survival after radical cystectomy
    Yair Lotan
    Department of Urology, University of Texas Southwestern Medical Center Dallas, TX 75390, USA
    Eur Urol 64:465-71. 2013
    ..There are no prospective studies validating the clinical utility of markers in bladder cancer...
  5. doi request reprint Predicting clinical outcomes after radical nephroureterectomy for upper tract urothelial carcinoma
    Eugene K Cha
    Department of Urology, Weill Cornell Medical College, New York Presbyterian Hospital, New York, NY 10065, USA
    Eur Urol 61:818-25. 2012
    ..Novel prognostic factors for patients after radical nephroureterectomy (RNU) for upper tract urothelial carcinoma (UTUC) have recently been described...
  6. doi request reprint Radical nephroureterectomy for pathologic T4 upper tract urothelial cancer: can oncologic outcomes be improved with multimodality therapy?
    Ramy F Youssef
    UT Southwestern Medical Center, Dallas, TX, USA
    Int Braz J Urol 39:614-21. 2013
    ..To report the outcomes of patients with pathologic T4 UTUC and investigate the potential impact of peri-operative chemotherapy combined with radical nephroureterectomy (RNU) and regional lymph node dissection (LND) on oncologic outcomes...
  7. doi request reprint Oncological outcomes after radical nephroureterectomy for upper tract urothelial carcinoma: comparison over the three decades
    Mehrad Adibi
    Department of Urology, UT Southwestern Medical Center, Dallas, TX 75390 9110, USA
    Int J Urol 19:1060-6. 2012
    ..To evaluate temporal trends in clinicopathological features and oncological outcomes after radical nephroureterectomy for upper tract urothelial carcinoma...
  8. ncbi request reprint Outcomes of radical cystectomy for transitional cell carcinoma of the bladder: a contemporary series from the Bladder Cancer Research Consortium
    Shahrokh F Shariat
    Department of Urology, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390, USA
    J Urol 176:2414-22; discussion 2422. 2006
    ..We present the characteristics and outcomes of a large, contemporary, consecutive series of patients treated with radical cystectomy and pelvic lymphadenectomy for transitional cell carcinoma of the bladder...
  9. doi request reprint Impact of smoking and smoking cessation on outcomes in bladder cancer patients treated with radical cystectomy
    Michael Rink
    Department of Urology, Weill Cornell Medical College, New York Presbyterian Hospital, New York, NY 10065, USA
    Eur Urol 64:456-64. 2013
    ..Cigarette smoking is the best-established risk factor for urothelial carcinoma development...
  10. ncbi request reprint Concomitant carcinoma in situ is a feature of aggressive disease in patients with organ-confined TCC at radical cystectomy
    Shahrokh F Shariat
    Department of Urology, University of Texas Southwestern Medical Center, Dallas, TX 75390 9110, USA
    Eur Urol 51:152-60. 2007
    ..The aim of this study was to assess whether presence of concomitant CIS has a detrimental effect on cancer control after radical cystectomy...
  11. doi request reprint Combination of multiple molecular markers can improve prognostication in patients with locally advanced and lymph node positive bladder cancer
    Shahrokh F Shariat
    Department of Urology, University of Texas Southwestern Medical Center, Dallas, Texas 10065, USA
    J Urol 183:68-75. 2010
    ..We also assessed whether the combination of molecular markers is superior to any individual biomarker...
  12. doi request reprint Survivin as a prognostic marker for urothelial carcinoma of the bladder: a multicenter external validation study
    Shahrokh F Shariat
    Departments of Urology and Pathology, University of Texas Southwestern Medical Center, Dallas, Texas, USA
    Clin Cancer Res 15:7012-9. 2009
    ..The aim of the current study was to externally validate the value of survivin as a prognostic marker for bladder cancer in a large multi-institutional cohort of patients treated with radical cystectomy...
  13. ncbi request reprint Use of combined apoptosis biomarkers for prediction of bladder cancer recurrence and mortality after radical cystectomy
    Jose A Karam
    Department of Urology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA
    Lancet Oncol 8:128-36. 2007
    ....
  14. doi request reprint p53 expression in patients with advanced urothelial cancer of the urinary bladder
    Shahrokh F Shariat
    Department of Urology, University of Texas Southwestern Medical Center, Dallas, TX, USA
    BJU Int 105:489-95. 2010
    ..To test whether assessing p53 expression could improve the ability to predict disease recurrence and disease-specific survival in a multi-institutional cohort of patients with advanced urothelial carcinoma of the urinary bladder (UCB)...
  15. doi request reprint Impact of renal function on eligibility for chemotherapy and survival in patients who have undergone radical nephro-ureterectomy
    Evanguelos Xylinas
    Department of Urology, Division of Medical Oncology SFS, Weill Cornell Medical College, New York Presbyterian Hospital, New York, NY 10065, USA
    BJU Int 112:453-61. 2013
    ..73 m(2) , respectively. Taken together with the rest of the literature, the findings of the study support the use of cisplatin-based chemotherapy, when indicated, in the neoadjuvant rather than adjuvant setting...
  16. doi request reprint The impact of previous ureteroscopic tumor ablation on oncologic outcomes after radical nephrouretectomy for upper urinary tract urothelial carcinoma
    Cenk Gurbuz
    University of Texas Southwestern Medical Center, Dallas, Texas 75390 9110, USA
    J Endourol 25:775-9. 2011
    ..Our data support the continued role of ureteroscopic ablation of UTUC in appropriately selected patients...
  17. ncbi request reprint Nomograms provide improved accuracy for predicting survival after radical cystectomy
    Shahrokh F Shariat
    Department of Urology, University of Texas Southwestern Medical Center, Dallas, Texas, and The Brady Urological Institute, The Johns Hopkins Hospital, Baltimore, MD, USA
    Clin Cancer Res 12:6663-76. 2006
    ....
  18. doi request reprint Association of angiogenesis related markers with bladder cancer outcomes and other molecular markers
    Shahrokh F Shariat
    Department of Urology, University of Texas Southwestern Medical Center, Dallas, Texas, USA
    J Urol 183:1744-50. 2010
    ....
  19. doi request reprint Primary adenocarcinoma of the urinary bladder: value of cell cycle biomarkers
    Payal Kapur
    Dept of Pathology, University of Texas Southwestern, 5323 Harry Hines Blvd, Dallas, TX 75390 9110, USA
    Am J Clin Pathol 135:822-30. 2011
    ..04). Stage, lymph node involvement, combined alterations of p27 and Ki-67, and combined alterations of all 5 biomarkers were associated with increased probability of disease recurrence and cancer-specific mortality (P < .05)...
  20. ncbi request reprint Caveolin-1 overexpression is associated with aggressive prostate cancer recurrence
    Jose A Karam
    Department of Urology, University of Texas Southwestern Medical Center, Dallas, TX 75390 9110, USA
    Prostate 67:614-22. 2007
    ....
  21. doi request reprint Bladder cancer screening in a high risk asymptomatic population using a point of care urine based protein tumor marker
    Yair Lotan
    Department of Urology, University of Texas Southwestern Medical Center, Dallas, Texas 75390 9110, USA
    J Urol 182:52-7; discussion 58. 2009
    ..We evaluated whether screening high risk asymptomatic individuals with a bladder tumor marker can lead to earlier detection and resultant down staging of bladder cancer...
  22. ncbi request reprint Prostate cancer disease-free survival after radical retropubic prostatectomy in patients older than 70 years compared to younger cohorts
    Bahaa S Malaeb
    Department of Urology, University of Minnesota, Minneapolis, MN 55455, USA
    Urol Oncol 25:291-7. 2007
    ..To evaluate the feasibility of radical retropubic prostatectomy (RRP) as an option for treating men older than 70 years with organ confined prostate cancer and to compare biochemical progression-free survival with younger cohorts...
  23. doi request reprint Upper urinary tract urothelial carcinoma with loco-regional nodal metastases: insights from the Upper Tract Urothelial Carcinoma Collaboration
    Ramy F Youssef
    UT Southwestern Medical Center, Dallas, TX, USA
    BJU Int 108:1286-91. 2011
    ..To describe a multicentre experience with preoperative platinum-based chemotherapy before radical nephroureterectomy (RNU) in patients with upper tract urothelial carcinoma (UTUC) with loco-regional nodal metastases...
  24. doi request reprint Urothelial carcinoma at the uretero-enteric junction: multi-center evaluation of oncologic outcomes after radical nephroureterectomy
    Ramy F Youssef
    University of Texas Southwestern Medical Center, Dallas, TX 75390, USA
    Urol Oncol 31:676-81. 2013
    ..Therefore, we evaluated oncologic outcomes of patients treated for urothelial carcinoma at the UEJ...
  25. ncbi request reprint Decreased DOC-2/DAB2 expression in urothelial carcinoma of the bladder
    Jose A Karam
    Department of Urology, University of Texas Southwestern Medical Center at Dallas, Dallas, Texas, USA
    Clin Cancer Res 13:4400-6. 2007
    ..Little is known about the expression of this gene in urothelial carcinoma of the bladder (UCB). We profiled DOC-2/DAB2 expression in mouse and human normal and neoplastic urothelia...
  26. pmc Impact of smoking on oncologic outcomes of upper tract urothelial carcinoma after radical nephroureterectomy
    Michael Rink
    Department of Urology, Weill Cornell Medical College, New York Presbyterian Hospital, New York, NY 10065, USA
    Eur Urol 63:1082-90. 2013
    ..Cigarette smoking is a common risk factor for developing upper tract urothelial carcinoma (UTUC)...
  27. doi request reprint Prognostic value of extranodal extension and other lymph node parameters in patients with upper tract urothelial carcinoma
    Harun Fajkovic
    Department of Urology, Weill Cornell Medical College, New York Presbyterian Hospital, New York, New York 10065, USA
    J Urol 187:845-51. 2012
    ..We assessed the prognostic value of extranodal extension and other lymph node parameters in a large multicenter cohort of patients with lymph node metastasis after radical nephroureterectomy...
  28. ncbi request reprint Intermediate comparison of partial nephrectomy and radiofrequency ablation for clinical T1a renal tumours
    Joshua M Stern
    Department of Urology, University of Texas, Southwestern Medical Center, Dallas, TX 75390 9110, USA
    BJU Int 100:287-90. 2007
    ....
  29. ncbi request reprint Ki-67 is an independent predictor of bladder cancer outcome in patients treated with radical cystectomy for organ-confined disease
    Vitaly Margulis
    Department of Urology, University of Texas Southwestern Medical Center, Dallas, Texas 75390 9110, USA
    Clin Cancer Res 12:7369-73. 2006
    ..We also assessed malignant lymph nodes from 50 of the 226 cystectomy patients...
  30. doi request reprint Obesity is associated with worse outcomes in patients with T1 high grade urothelial carcinoma of the bladder
    Luis A Kluth
    Department of Urology, Weill Cornell Medical College, New York Presbyterian Hospital, New York, New York 10065, USA
    J Urol 190:480-6. 2013
    ..We hypothesized that higher body mass index is associated with worse outcomes in patients with clinical primary T1 high grade urothelial carcinoma of the bladder...
  31. doi request reprint Disease-free survival as a surrogate for overall survival in upper tract urothelial carcinoma
    Harun Fajkovic
    Department of Urology, Weill Cornell Medical College, New York Presbyterian Hospital, 525 East 68th St, Starr 900, New York, NY 10065, USA
    World J Urol 31:5-11. 2013
    ..We hypothesized that disease-free survival (DFS) could be a surrogate endpoint for OS in upper tract urothelial carcinoma (UTUC) patients treated with radical nephroureterectomy (RNU)...
  32. doi request reprint The impact of tumor multifocality on outcomes in patients treated with radical nephroureterectomy
    Thomas F Chromecki
    Department of Urology, Weill Cornell Medical College, New York Presbyterian Hospital, New York, NY 10065, USA
    Eur Urol 61:245-53. 2012
    ..The prognostic impact of multifocal upper-tract urothelial carcinoma (UTUC) is poorly understood...
  33. ncbi request reprint Cooperative effect of cell-cycle regulators expression on bladder cancer development and biologic aggressiveness
    Shahrokh F Shariat
    Department of Urology, University of Texas Southwestern Medical Center, Dallas, TX 75390 9110, USA
    Mod Pathol 20:445-59. 2007
    ..In contrast to the use of single biological markers, evaluation of their combined status may improve prognostic models and help identify patients who might benefit from adjuvant therapies and in decision-making...
  34. ncbi request reprint Survivin expression in patients with non-muscle-invasive urothelial cell carcinoma of the bladder
    Jose A Karam
    Department of Urology, University of Texas Southwestern Medical Center at Dallas, Dallas, Texas 75390 9110, USA
    Urology 70:482-6. 2007
    ..Our objectives were to evaluate the association of survivin expression with the presence of urothelial cell carcinoma of the bladder and clinical outcomes in patients with non-muscle-invasive urothelial cell carcinoma of the bladder...
  35. ncbi request reprint Prognostic value of syndecan-1 expression in patients treated with radical prostatectomy
    Shahrokh F Shariat
    Department of Urology, University of Texas Southwestern Medical Center, Dallas, TX 75390 9110, USA
    BJU Int 101:232-7. 2008
    ....
  36. doi request reprint Advanced patient age is associated with inferior cancer-specific survival after radical nephroureterectomy
    Shahrokh F Shariat
    University of Texas Southwestern, Dallas, TX, USA
    BJU Int 105:1672-7. 2010
    ..To assess the impact of patient age on outcomes after radical nephroureterectomy (RNU) for upper tract urothelial carcinoma (UTUC)...
  37. ncbi request reprint Multiple biomarkers improve prediction of bladder cancer recurrence and mortality in patients undergoing cystectomy
    Shahrokh F Shariat
    Department of Urology, University of Texas Southwestern Medical Center, Dallas, Texas 75390 9110, USA
    Cancer 112:315-25. 2008
    ....
  38. doi request reprint Predictive value of plasma hepatocyte growth factor/scatter factor levels in patients with clinically localized prostate cancer
    Amit Gupta
    Department of Urology, The University of Texas Southwestern Medical Center, Dallas, Texas 75390 9110, USA
    Clin Cancer Res 14:7385-90. 2008
    ..We assessed whether preoperative plasma levels of HGF can enhance the accuracy of standard models for predicting pathologic features and clinical outcomes...
  39. doi request reprint Preoperative multivariable prognostic model for prediction of nonorgan confined urothelial carcinoma of the upper urinary tract
    Vitaly Margulis
    Department of Urology, UT Southwestern Medical Center, Dallas, Texas 75390 9110, USA
    J Urol 184:453-8. 2010
    ..We created a prognostic tool for the accurate preoperative prediction of nonorgan confined upper tract urothelial carcinoma...
  40. doi request reprint BAP1 immunohistochemistry predicts outcomes in a multi-institutional cohort with clear cell renal cell carcinoma
    Payal Kapur
    Department of Pathology PK, University of Texas Southwestern Medical Center, Dallas, Texas Department of Urology PK, yl, VM, University of Texas Southwestern Medical Center, Dallas, Texas Department of Internal Medicine JB, University of Texas Southwestern Medical Center, Dallas, Texas Department of Developmental Biology JB, University of Texas Southwestern Medical Center, Dallas, Texas Simmons Cancer Center XJX, JB, University of Texas Southwestern Medical Center, Dallas, Texas Department of Urology, Penn State Milton S Hershey Medical Center JDR, Hershey, Pennsylvania Department of Pathology, University of Pittsburgh Medical Center MTT, Pittsburgh, Pennsylvania Department of Urology, University of Munich PN, AB, Munich, Germany Department of Urology, Paracelsus Klinik Golzheim, Dusseldorf, Germany PB Department of Urology, Central Hospital of Bolzano CS, Bolzano, Italy Department of Urology, Medical University of Vienna, Vienna General Hospital CS, SFS, Vienna, Bogot
    J Urol 191:603-10. 2014
    ..We investigated the clinicopathological significance and oncologic outcomes of BAP1 loss using a previously validated immunohistochemical assay...
  41. doi request reprint Prediction of true nodal status in patients with pathological lymph node negative upper tract urothelial carcinoma at radical nephroureterectomy
    Evanguelos Xylinas
    Department of Urology, Weill Cornell Medical College, New York Presbyterian Hospital, New York, New York 10065, USA
    J Urol 189:468-73. 2013
    ..We developed a pathological nodal staging model that allows quantification of the likelihood that a patient with pathologically node negative disease has, indeed, no lymph node metastasis...
  42. doi request reprint Impact of histological variants on oncological outcomes of patients with urothelial carcinoma of the bladder treated with radical cystectomy
    Evanguelos Xylinas
    Department of Urology, Weill Cornell Medical College, New York, NY 10065, USA
    Eur J Cancer 49:1889-97. 2013
    ..To investigate the impact of variant histologies of urothelial carcinoma of the bladder (UCB) on oncologic outcomes after radical cystectomy (RC)...
  43. ncbi request reprint The influence of clinical and pathological stage discrepancy on cancer specific survival in patients treated for renal cell carcinoma
    Robert S Svatek
    Department of Urology, University of Texas Southwestern Medical Center, Dallas, Texas 75390 9110, USA
    J Urol 176:1321-5; discussion 125. 2006
    ....
  44. ncbi request reprint Variability in the performance of nuclear matrix protein 22 for the detection of bladder cancer
    Shahrokh F Shariat
    Department of Urology, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390, USA
    J Urol 176:919-26; discussion 926. 2006
    ..We assessed variability in the diagnostic performance of NMP22 for detecting recurrence and progression in patients with Ta, T1, and/or CIS transitional cell carcinoma of the bladder in a large international cohort...
  45. ncbi request reprint Laparoscopic interstitial laser coagulation of renal tissue with and without hilar occlusion in the porcine model
    Matthew T Gettman
    Department of Pathology, The University of Texas Southwestern Medical Center at Dallas, Dallas, Texas 75390 9110, USA
    J Endourol 16:565-70. 2002
    ..To evaluate the safety and efficacy of interstitial laser coagulation (ILC), applied via a laparoscopic approach, with and without hilar occlusion in the porcine model...
  46. ncbi request reprint Discrepancy between clinical and pathologic stage: impact on prognosis after radical cystectomy
    Shahrokh F Shariat
    Department of Urology, University of Texas Southwestern Medical Center, Dallas, Texas 75390 9110, USA
    Eur Urol 51:137-49; discussion 149-51. 2007
    ..We compared clinical and pathologic staging in a large, contemporary, consecutive series of patients who were treated with radical cystectomy and pelvic lymphadenectomy, and determined the effect of stage discrepancy on outcomes...
  47. doi request reprint The effect of the approach to radical prostatectomy on the profitability of hospitals and surgeons
    Yair Lotan
    Department of Urology, University of Texas Southwestern Medical Center, Dallas, TX, USA
    BJU Int 105:1531-5. 2010
    ....
  48. doi request reprint Prospective comparison of molecular signatures in urothelial cancer of the bladder and the upper urinary tract--is there evidence for discordant biology?
    Laura Maria Krabbe
    Department of Urology, University of Texas Southwestern Medical Center, Dallas, Texas Department of Urology, University of Muenster Medical Center, Muenster, Germany
    J Urol 191:926-31. 2014
    ..We prospectively evaluate molecular profiles of upper tract urothelial carcinoma and bladder cancer using a cell cycle biomarker panel...
  49. doi request reprint Comprehensive handbook for developing a bladder cancer cystectomy database
    Yair Lotan
    The University of Texas Southwestern Medical Center, Dallas, TX 75390, USA
    Urol Oncol 31:812-26. 2013
    ..In an effort to standardize data collection for research regarding bladder cancer, the Bladder Cancer Working Group sought to provide a handbook that can be used as a guide for prospective or retrospective data collection...
  50. ncbi request reprint Expression of cyclooxygenase-2 in normal urothelium, and superficial and advanced transitional cell carcinoma of bladder
    Vitaly Margulis
    Department of Urology, University of Texas Southwestern Medical Center at Dallas, Dallas, Texas 75390 9110, USA
    J Urol 177:1163-8. 2007
    ....
  51. doi request reprint Predictors of survival in patients with soft tissue surgical margin involvement at radical cystectomy
    Evanguelos Xylinas
    Department of Urology, Weill Cornell Medical College, New York Presbyterian Hospital, New York, NY, USA
    Ann Surg Oncol 20:1027-34. 2013
    ..We sought to describe the oncologic outcomes, identify predictors, and assess the impact of location and multifocality in patients with positive STSMs at RC...
  52. doi request reprint Biomolecular predictors of urothelial cancer behavior and treatment outcomes
    Michael Rink
    Department of Urology, New York Presbyterian Hospital, Weill Medical College of Cornell University, New York, NY 10065, USA
    Curr Urol Rep 13:122-35. 2012
    ..We discuss the predictive and prognostic value of biomarkers at different stages of UCB. There is no doubt that a panel of biomarkers will eventually improve our clinical decision-making with regard to treatment and follow-up...
  53. doi request reprint Risk stratification of organ confined bladder cancer after radical cystectomy using cell cycle related biomarkers
    Shahrokh F Shariat
    Department of Urology, Weill Cornell Medical Center, New York, NY, USA
    J Urol 187:457-62. 2012
    ..We tested whether assessing the expression of cell cycle related proteins (p53, pRB, p21 and p27) could predict clinical outcomes after radical cystectomy in patients with organ confined urothelial carcinoma of the bladder...
  54. pmc High-risk patients with hematuria are not evaluated according to guideline recommendations
    Keren Elias
    Department of Urology, University of Texas Southwestern Medical Center at Dallas, TX, USA
    Cancer 116:2954-9. 2010
    ..To determine whether high-risk patients with hematuria receive evaluation according to guideline recommendations...
  55. doi request reprint Outcomes of patients with clinical T1 grade 3 urothelial cell bladder carcinoma treated with radical cystectomy
    Amit Gupta
    Department of Urology, University of Texas Southwestern Medical Center, Dallas, Texas 75390 9110, USA
    Urology 71:302-7. 2008
    ..The aim of the present study was to assess the pathologic features and clinical outcomes of patients with clinical T1 grade 3 urothelial cell bladder carcinoma (UCBC) treated with radical cystectomy...
  56. doi request reprint General anesthesia and contrast-enhanced computed tomography to optimize renal percutaneous radiofrequency ablation: multi-institutional intermediate-term results
    Amit Gupta
    Department of Urology, The University of Texas Southwestern Medical Center, Dallas, Texas 75390 9110, USA
    J Endourol 23:1099-105. 2009
    ..We evaluated intermediate-term outcomes of patients undergoing percutaneous contrast-enhanced computed tomography (CT)-guided radiofrequency ablation (RFA) under general anesthesia (GA) at two high-volume centers...
  57. doi request reprint Bilharzial vs non-bilharzial related bladder cancer: pathological characteristics and value of cyclooxygenase-2 expression
    Ramy Youssef
    Urology and Pathology, University of Texas Southwestern Medical Center, Dallas, Texas, USA
    BJU Int 108:31-7. 2011
    ..We also determined the clinico-pathological differences between BBC and NBBC...
  58. ncbi request reprint Despite PSA screening and the control by radical prostatectomy, patients treatment fails and have a PSA recurrence
    Yair Lotan
    Department of Urology, The University of Texas Southwestern Medical Center, Dallas, TX 75309 9110, USA
    Eur Urol 52:453-4. 2007
  59. ncbi request reprint Survivin expression is associated with bladder cancer presence, stage, progression, and mortality
    Shahrokh F Shariat
    Department of Urology, University of Texas Southwestern Medical Center at Dallas, Texas 75390 9110, USA
    Cancer 109:1106-13. 2007
    ....
  60. ncbi request reprint Efficacy of ablative high-dose-per-fraction radiation for implanted human renal cell cancer in a nude mouse model
    Lance Walsh
    Department of Urology, The University of Texas Southwestern Medical Center, Dallas, Texas 75390 9110, USA
    Eur Urol 50:795-800; discussion 800. 2006
    ..We investigated the use of ablative hypofractionation in treating human renal cell carcinoma using a nude mouse model...
  61. ncbi request reprint Preoperative plasma HER2 and epidermal growth factor receptor for staging and prognostication in patients with clinically localized prostate cancer
    Shahrokh F Shariat
    Department of Urology, University of Texas Southwestern Medical Center at Dallas, Dallas, Texas 75390 9110, USA
    Clin Cancer Res 13:5377-84. 2007
    ..We tested the hypothesis that plasma levels of HER2 and/or EGFR are associated with prostate cancer stage and prognosis in patients with clinically localized disease...
  62. ncbi request reprint Soluble Fas--a promising novel urinary marker for the detection of recurrent superficial bladder cancer
    Robert S Svatek
    Department of Urology, University of Texas Southwestern Medical Center, Dallas, Texas 75390 9110, USA
    Cancer 106:1701-7. 2006
    ....
  63. ncbi request reprint Predictive value of primary Gleason pattern 4 in patients with Gleason score 7 tumours treated with radical prostatectomy
    Seyed M Khoddami
    Department of Urology, The University of Texas South Western Medical Center, Dallas, USA
    BJU Int 94:42-6. 2004
    ..To examine whether Gleason score (GS) 3 + 4 and 4 + 3 cancers at radical prostatectomy behave differently and whether this behaviour is independently associated with prostate cancer outcome...
  64. ncbi request reprint The percent of biopsy cores positive for cancer is a predictor of advanced pathological stage and poor clinical outcomes in patients treated with radical prostatectomy
    Yair Lotan
    Departments of Urology and Pathology, University of Texas Southwestern Medical Center at Dallas, Dallas, Texas 75390 9110, USA
    J Urol 171:2209-14. 2004
    ..We examined if the percent of positive biopsies is associated with features of biologically aggressive prostate cancer, biochemical progression and development of distant metastases in patients undergoing radical prostatectomy (RP)...
  65. pmc Laparoscopic partial nephrectomy using holmium laser in a porcine model
    Yair Lotan
    Department of Urology, University of Texas Southwestern Medical Center at Dallas, 75390 9110, USA
    JSLS 8:51-5. 2004
    ..To evaluate the utility of the holmium laser for partial nephrectomy in a porcine model...
  66. doi request reprint Prognostic role of cell cycle and proliferative biomarkers in patients with clear cell renal cell carcinoma
    Bishoy A Gayed
    Departments of Urology and Pathology PK, University of Texas Southwestern Medical Center, Dallas, Texas
    J Urol 190:1662-7. 2013
    ..In this proof of principle study we systematically evaluate the association of aberrant expression of cell cycle regulators and proliferative markers and their effect on oncologic outcomes of patients with clear cell renal carcinoma...
  67. doi request reprint Impact of smoking on outcomes of patients with a history of recurrent nonmuscle invasive bladder cancer
    Michael Rink
    Department of Urology, Weill Cornell Medical College New York Presbyterian Hospital, New York, New York 10065, USA
    J Urol 188:2120-7. 2012
    ..We investigated the effects of cigarette smoking status, cumulative exposure and time from cessation on disease recurrence and progression in patients with a history of recurrent nonmuscle invasive bladder cancer...
  68. doi request reprint Comparative analysis of oncologic outcomes of partial ureterectomy vs radical nephroureterectomy in upper tract urothelial carcinoma
    Aditya Bagrodia
    Department of Urology, University of Texas Southwestern Medical Center, Dallas, TX 75390 9110, USA
    Urology 81:972-7. 2013
    ..To compare oncologic outcomes in an international cohort of patients who underwent either partial ureterectomy (PU) or radical nephroureterectomy (RNU) for upper tract urothelial carcinoma (UTUC)...
  69. doi request reprint How much is a kidney worth? Cost-effectiveness of routine imaging after ureteroscopy to prevent silent obstruction
    Tori N Sutherland
    Department of Urology, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA
    J Urol 189:2136-41. 2013
    ..We evaluated the cost-effectiveness of routine postoperative imaging after ureteroscopy...
  70. doi request reprint p53 predictive value for pT1-2 N0 disease at radical cystectomy
    Shahrokh F Shariat
    Department of Urology, University of Texas Southwestern Medical Center, Dallas, USA
    J Urol 182:907-13. 2009
    ..We determined whether p53 expression would improve the prediction of disease progression after radical cystectomy for pT1-2N0M0 UCB...
  71. ncbi request reprint Pre-operative percent free PSA predicts clinical outcomes in patients treated with radical prostatectomy with total PSA levels below 10 ng/ml
    Shahrokh F Shariat
    Department of Urology, The University of Texas Southwestern Medical Center at Dallas, TX 75390 9110, USA
    Eur Urol 49:293-302. 2006
    ..To evaluate the association of total prostate specific antigen (T-PSA) and percent free PSA (%F-PSA) with prostate cancer outcomes in patients treated with radical prostatectomy (RP)...
  72. doi request reprint Human epidermal growth factor receptor 2 expression status provides independent prognostic information in patients with urothelial carcinoma of the urinary bladder
    Christian Bolenz
    Departments of Urology, University of Texas Southwestern Medical Center, Dallas, TX, USA
    BJU Int 106:1216-22. 2010
    ..to test whether the expression of human epidermal growth factor receptor 2 (HER-2) is of prognostic value in a contemporary cohort of patients with urothelial carcinoma of the urinary bladder (UCB)...
  73. ncbi request reprint Association of cyclin D1 and E1 expression with disease progression and biomarkers in patients with nonmuscle-invasive urothelial cell carcinoma of the bladder
    Shahrokh F Shariat
    Department of Urology, University of Texas Southwestern Medical Center at Dallas, Dallas, TX 75390 9110, USA
    Urol Oncol 25:468-75. 2007
    ..To determine the association of cyclin D1 and E1 expression with bladder cancer presence, clinical and molecular characteristics, and disease progression in patients with nonmuscle-invasive urothelial cell carcinoma of the bladder...
  74. ncbi request reprint Characteristics and outcomes of patients with carcinoma in situ only at radical cystectomy
    Shahrokh F Shariat
    Department of Urology, University of Texas Southwestern Medical Center, Dallas, Texas 75390 9110, USA
    Urology 68:538-42. 2006
    ..To describe the cancer-specific outcomes of patients with pathologic carcinoma in situ (CIS) only at radical cystectomy...
  75. ncbi request reprint Contemporary laparoscopic and open radical retropubic prostatectomy: pathologic outcomes and Kattan postoperative nomograms are equivalent
    Sangtae Park
    Department of Urology, University of Texas Southwestern Medical Center, Dallas, Texas 75390 9110, USA
    Urology 69:118-22. 2007
    ....
  76. doi request reprint Prognostic effect of urinary bladder carcinoma in situ on clinical outcome of subsequent upper tract urothelial carcinoma
    Ramy F Youssef
    University of Texas Southwestern Medical Center, Dallas, TX 75390 9110, USA
    Urology 77:861-6. 2011
    ..Urinary bladder CIS was previously reported to be among the independent risk factors for the development of UTUC...
  77. pmc Persistent uroplakin expression in advanced urothelial carcinomas: implications in urothelial tumor progression and clinical outcome
    Hong Ying Huang
    Department of Urology, NYU Cancer Institute, New York University School of Medicine, New York, NY 10016, USA
    Hum Pathol 38:1703-13. 2007
    ..Our results also suggest that UP-positive and -negative carcinomas have different clonal origins or may be derived from different cancer stem cells...
  78. doi request reprint Cost-effectiveness of prostate cancer chemoprevention: a quality of life-years analysis
    Robert S Svatek
    Department of Urology, The University of Texas Southwestern Medical Center, Dallas, TX 75390 9110, USA
    Cancer 112:1058-65. 2008
    ..8% (risk reduction) but questions remain regarding the cost-effectiveness of widespread utilization. The purpose of the current analysis was to evaluate the cost-effectiveness of chemoprevention utilizing a quality-of-life adjustment...
  79. doi request reprint Radiofrequency ablation of small renal cortical tumours in healthy adults: renal function preservation and intermediate oncological outcome
    Joshua M Stern
    Department of Urology, University of Texas Southwestern Medical Center, Dallas, TX, USA
    BJU Int 104:786-9. 2009
    ....
  80. ncbi request reprint Cost comparison of hand assisted laparoscopic nephrectomy and open nephrectomy: analysis of individual parameters
    Yair Lotan
    Department of Urology, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390, USA
    J Urol 170:752-5. 2003
    ..In response to budgetary pressure at our large county hospital we reviewed the published experience and identified the cost components of HAL that could be targeted to decrease procedure cost...
  81. doi request reprint Outcomes of radical nephroureterectomy: a series from the Upper Tract Urothelial Carcinoma Collaboration
    Vitaly Margulis
    Department of Urology, The University of Texas M D Anderson Cancer Center, Houston, Texas, USA
    Cancer 115:1224-33. 2009
    ..A large series of patients treated with radical nephroureterectomy for UTUC were studied, and variables associated with poor prognosis were identified...
  82. ncbi request reprint Evaluation of costs and morbidity associated with laparoscopic radiofrequency ablation and laparoscopic partial nephrectomy for treating small renal tumours
    Karim Bensalah
    Department of Urology, University of Texas South western Medical Center at Dallas, Dallas, Texas 75390 9110, USA
    BJU Int 101:467-71. 2008
    ..To compare the costs and morbidity of laparoscopic radiofrequency ablation (LRFA) and laparoscopic partial nephrectomy (LPN) for treating small localized renal tumours...
  83. doi request reprint Prognostic risk stratification of pathological stage T3N0 bladder cancer after radical cystectomy
    Guru Sonpavde
    Michael E DeBakey Veterans Affairs Medical Center, Dallas, Texas, USA
    J Urol 185:1216-21. 2011
    ....
  84. doi request reprint Sirolimus in metatastic renal cell carcinoma
    James Brugarolas
    Department of Internal Medicine Oncology Division, Simmons Comprehensive Cancer Center, University of Texas Southwestern Medical Center, Dallas, TX, USA
    J Clin Oncol 26:3457-60. 2008
  85. doi request reprint Residual fragments after percutaneous nephrolithotomy: cost comparison of immediate second look flexible nephroscopy versus expectant management
    Jay D Raman
    Department of Urology, University of Texas Southwestern Medical Center, Dallas, Texas, USA
    J Urol 183:188-93. 2010
    ..We performed a cost comparison of immediate second look flexible nephroscopy vs expectant management for post-percutaneous nephrostolithotomy residual fragments...
  86. ncbi request reprint Lymphovascular invasion is independently associated with overall survival, cause-specific survival, and local and distant recurrence in patients with negative lymph nodes at radical cystectomy
    Yair Lotan
    Department of Urology, The University of Texas Southwestern Medical Center at Dallas, Dallas, TX 75390 9110, USA
    J Clin Oncol 23:6533-9. 2005
    ..We hypothesized that bladder cancer patients with associated lymphovascular invasion (LVI) are at increased risk of occult metastases...
  87. doi request reprint Cost comparison of robotic, laparoscopic, and open radical prostatectomy for prostate cancer
    Christian Bolenz
    Department of Urology, University of Texas Southwestern Medical Center at Dallas, TX 75390 9110, USA
    Eur Urol 57:453-8. 2010
    ..Demand and utilization of minimally invasive approaches to radical prostatectomy have increased in recent years, but comparative studies on cost are lacking...
  88. doi request reprint International validation of the prognostic value of lymphovascular invasion in patients treated with radical cystectomy
    Shahrokh F Shariat
    University of Texas Southwestern Medical Center, Dallas, Texas, USA
    BJU Int 105:1402-12. 2010
    ..To externally validate the prognostic value of lymphovascular invasion (LVI) in a large international cohort of patients treated with radical cystectomy (RC) for urothelial carcinoma of the bladder (UCB)...
  89. ncbi request reprint Radiofrequency ablation for T1a tumors in a solitary kidney: promising intermediate oncologic and renal function outcomes
    Jay D Raman
    Department of Urology, University of Texas, Southwestern Medical Center, Dallas, Texas, USA
    Can J Urol 15:3980-5. 2008
    ..The experience with radiofrequency ablation (RFA) in solitary kidneys is limited in numbers and follow-up. Therefore, we report our oncologic and renal function outcomes of RFA for T1a tumors in patients with a solitary kidney...
  90. ncbi request reprint Histopathology of surgically managed renal tumors: analysis of a contemporary series
    David A Duchene
    Department of Urology, University of Texas Southwestern Medical Center, Dallas, Texas 75390 9110, USA
    Urology 62:827-30. 2003
    ..A significant proportion of small renal tumors are benign or are low-grade malignancies...
  91. doi request reprint The screening for Occult Renal Disease (SCORED) value is associated with a higher risk for having or developing chronic kidney disease in patients treated for small, unilateral renal masses
    Steven M Lucas
    Department of Urology, University of Texas Southwestern Medical Center at Dallas, Dallas, Texas, USA
    Cancer 113:2681-6. 2008
    ..73 m2). In this study, the authors investigated whether the Screening for Occult Renal Disease (SCORED) model could identify patients with renal masses who were at risk for having or developing CKD...
  92. doi request reprint Impact of body mass index on cost and clinical outcomes after percutaneous nephrostolithotomy
    Aditya Bagrodia
    Department of Urology, University of Texas Southwestern Medical Center, Dallas, Texas 75390 9110, USA
    Urology 72:756-60. 2008
    ..To evaluate the impact of body mass index (BMI) on clinical outcomes and costs associated with percutaneous nephrostolithotomy (PCNL)...
  93. ncbi request reprint Laparoscopic versus open retroperitoneal lymph node dissection: a cost analysis
    Kenneth Ogan
    Clinical Center for Minimally Invasive Urologic Cancer Treatment, Dallas, Texas, USA
    J Urol 168:1945-9; discussion 1949. 2002
    ....
  94. ncbi request reprint Cost-effectiveness of a modified care protocol substituting bladder tumor markers for cystoscopy for the followup of patients with transitional cell carcinoma of the bladder: a decision analytical approach
    Yair Lotan
    Department of Urology, University of Texas Southwestern Medical Center at Dallas, Dallas, TX, USA
    J Urol 167:75-9. 2002
    ....
  95. ncbi request reprint Survivin: a promising biomarker for detection and prognosis of bladder cancer
    Vitaly Margulis
    Department of Urology, The University of Texas M D Anderson Cancer Center, Houston, TX, USA
    World J Urol 26:59-65. 2008
    ..These preliminary findings should now be confirmed in large prospective trials. Furthermore, simplified, quantitative and reproducible assays need to be developed and validated for the detection of Survivin and its different isoforms...
  96. ncbi request reprint Cost-effective treatment for ureteropelvic junction obstruction: a decision tree analysis
    Matthew T Gettman
    Department of Urology, University of Texas Southwestern Medical Center, Dallas, TX, USA
    J Urol 169:228-32. 2003
    ..We determined the optimal treatment for primary ureteropelvic junction obstruction based on cost using a decision tree model...
  97. doi request reprint Contemporary use of perioperative cisplatin-based chemotherapy in patients with muscle-invasive bladder cancer
    Ganesh V Raj
    Department of Urology, University of Texas Southwestern Medical Center at Dallas, Dallas, Texas 75390 9110, USA
    Cancer 117:276-82. 2011
    ..Our objective was to determine the patterns of utilization of neoadjuvant chemotherapy in patients undergoing RC for muscle invasive bladder cancer in a contemporary cohort in a tertiary care center...
  98. ncbi request reprint Predictive value of cell cycle biomarkers in nonmuscle invasive bladder transitional cell carcinoma
    Shahrokh F Shariat
    Department of Urology, University of Texas Southwestern Medical Center, Dallas, Texas 75390 9110, USA
    J Urol 177:481-7; discussion 487. 2007
    ..We determined whether the combined expression of p53, p21, p27 and pRB is associated with outcomes of patients with nonmuscle invasive bladder transitional cell carcinoma...
  99. ncbi request reprint International comparison of cost effectiveness of medical management strategies for nephrolithiasis
    Yair Lotan
    Department of Urology, The University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, TX 75390, USA
    Urol Res 33:223-30. 2005
    ..The differential resource allocation to different components of a healthcare system (i.e. subsidized medication versus surgical treatment) in different countries determines the cost effectiveness of various treatment strategies...
  100. doi request reprint Does obesity impact the costs of partial and radical nephrectomy?
    Karim Bensalah
    Department of Urology, University of Texas Southwestern Medical Center at Dallas, Dallas, Texas 75390 9110, USA
    J Urol 179:1714-7; discussion 1717-8. 2008
    ..We analyzed the impact of obesity on the costs of partial and radical nephrectomy...
  101. ncbi request reprint Correlation of cyclin D1 and E1 expression with bladder cancer presence, invasion, progression, and metastasis
    Shahrokh F Shariat
    Department of Urology, University of Texas Southwestern Medical Center at Dallas, TX 75390 9110, USA
    Hum Pathol 37:1568-76. 2006
    ..Cyclin E1 expression stratifies patients with bladder transitional cell carcinoma into those with more "indolent" behavior and those with features of biologically and clinically aggressive disease...