Angel Lopez-Candales

Summary

Affiliation: University of Pittsburgh
Country: USA

Publications

  1. ncbi request reprint Symptomatic improvement in patients treated with intermittent infusion of inotropes: a double-blind placebo controled pilot study
    Angel Lopez-Candales
    Cardiovascular Institute, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA
    J Med 33:129-46. 2002
  2. ncbi request reprint Metabolic syndrome X: a comprehensive review of the pathophysiology and recommended therapy
    A Lopez-Candales
    Cardiovascular Institute, University of Pittsburgh, Pennsylvania, USA
    J Med 32:283-300. 2001
  3. ncbi request reprint The importance of increased interatrial septal thickness in patients with atrial fibrillation: a transesophageal echocardiographic study
    Angel Lopez-Candales
    Cardiovascular Institute at the University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania 15213, USA
    Echocardiography 22:408-14. 2005
  4. ncbi request reprint Mitral valve contour in short axis: a useful view in the diagnosis of mitral valve prolapse
    Angel Lopez-Candales
    FACC of the Cardiovascular Institute, University of Pittsburgh Medical Center, Pittsburgh, Pensylvania, USA
    J Med 35:221-31. 2004
  5. ncbi request reprint Are there any ethnic differences in the number of coronary artery bypass and valve heart surgeries among Caucasians, African Americans and Puerto Ricans? The western New York experience
    Angel Lopez-Candales
    University of Pittsburgh Medical Center, Cardiovascular Institute, S560 Scaife Hall, 200 Lothrop Street Pittsburgh, PA 15213, USA
    J Med 35:211-20. 2004
  6. ncbi request reprint Need for hospice and palliative care services in patients with end-stage heart failure treated with intermittent infusion of inotropes
    Angel L López-Candales
    University of Pittsburgh Medical Center, Cardiovascular Institute, Pittsburgh, Pennsylvania 15213, USA
    Clin Cardiol 27:23-8. 2004
  7. ncbi request reprint Cardiovascular diseases: a review of the Hispanic perspective. Awareness is the first step to action
    Angel Lopez-Candales
    University of Pittsburgh Medical Center, Cardiovascular Institute, Pittsburgh, PA 15213, USA
    J Med 33:227-45. 2002
  8. ncbi request reprint Is the presence of interatrial septal hypertrophy a marker for atrial fibrillation in the elderly?
    Angel Lopez-Candales
    University of Pittsburgh Medical Center, University of Pittsburgh Cardiovascular Institute, PA 15213, USA
    Am J Geriatr Cardiol 11:399-403. 2002
  9. ncbi request reprint Comparative echocardiographic analysis of mitral and tricuspid annular motion: differences explained with proposed anatomic-structural correlates
    Angel Lopez-Candales
    Cardiovascular Institute, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania 15213 2582, USA
    Echocardiography 24:353-9. 2007
  10. ncbi request reprint Tricuspid annular systolic velocity: a useful measurement in determining right ventricular systolic function regardless of pulmonary artery pressures
    Neil Saxena
    Cardiovascular Institute at the University of Pittsburgh Medical Center, 200 Lothrop Street, Pittsburgh, PA 15213, USA
    Echocardiography 23:750-5. 2006

Collaborators

Detail Information

Publications48

  1. ncbi request reprint Symptomatic improvement in patients treated with intermittent infusion of inotropes: a double-blind placebo controled pilot study
    Angel Lopez-Candales
    Cardiovascular Institute, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA
    J Med 33:129-46. 2002
    ..Furthermore, infusion of inotropes resulted in a significant improvement on 6-minute walk test scores than placebo. It also appears that milrinone confers all these benefits sooner than dobutamine...
  2. ncbi request reprint Metabolic syndrome X: a comprehensive review of the pathophysiology and recommended therapy
    A Lopez-Candales
    Cardiovascular Institute, University of Pittsburgh, Pennsylvania, USA
    J Med 32:283-300. 2001
    ....
  3. ncbi request reprint The importance of increased interatrial septal thickness in patients with atrial fibrillation: a transesophageal echocardiographic study
    Angel Lopez-Candales
    Cardiovascular Institute at the University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania 15213, USA
    Echocardiography 22:408-14. 2005
    ..Although several reports have suggested that AF in humans may be a consequence of these mechanisms, no study has correlated the presence of AF with interatrial septal thickness (IAST)...
  4. ncbi request reprint Mitral valve contour in short axis: a useful view in the diagnosis of mitral valve prolapse
    Angel Lopez-Candales
    FACC of the Cardiovascular Institute, University of Pittsburgh Medical Center, Pittsburgh, Pensylvania, USA
    J Med 35:221-31. 2004
    ..These findings should be validated in a double blind prospective study...
  5. ncbi request reprint Are there any ethnic differences in the number of coronary artery bypass and valve heart surgeries among Caucasians, African Americans and Puerto Ricans? The western New York experience
    Angel Lopez-Candales
    University of Pittsburgh Medical Center, Cardiovascular Institute, S560 Scaife Hall, 200 Lothrop Street Pittsburgh, PA 15213, USA
    J Med 35:211-20. 2004
    ..It also emphasizes the need to promptly identify these deficiencies, particularly when considering that Hispanics are the most rapidly increasing minority ethnic population in the United States...
  6. ncbi request reprint Need for hospice and palliative care services in patients with end-stage heart failure treated with intermittent infusion of inotropes
    Angel L López-Candales
    University of Pittsburgh Medical Center, Cardiovascular Institute, Pittsburgh, Pennsylvania 15213, USA
    Clin Cardiol 27:23-8. 2004
    ..However, there are no data on the need for these services among patients with end-stage heart failure receiving intermittent infusion of intravenous inotropes...
  7. ncbi request reprint Cardiovascular diseases: a review of the Hispanic perspective. Awareness is the first step to action
    Angel Lopez-Candales
    University of Pittsburgh Medical Center, Cardiovascular Institute, Pittsburgh, PA 15213, USA
    J Med 33:227-45. 2002
    ....
  8. ncbi request reprint Is the presence of interatrial septal hypertrophy a marker for atrial fibrillation in the elderly?
    Angel Lopez-Candales
    University of Pittsburgh Medical Center, University of Pittsburgh Cardiovascular Institute, PA 15213, USA
    Am J Geriatr Cardiol 11:399-403. 2002
    ..Although the stimulus for the increased thickness of the atrial septum remains elusive, IST may identify a structural cause for atrial fibrillation in elderly patients that is easily identified by transthoracic echocardiography...
  9. ncbi request reprint Comparative echocardiographic analysis of mitral and tricuspid annular motion: differences explained with proposed anatomic-structural correlates
    Angel Lopez-Candales
    Cardiovascular Institute, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania 15213 2582, USA
    Echocardiography 24:353-9. 2007
    ..We elected to use M-mode to examine the extent and timing of mitral and tricuspid AM events...
  10. ncbi request reprint Tricuspid annular systolic velocity: a useful measurement in determining right ventricular systolic function regardless of pulmonary artery pressures
    Neil Saxena
    Cardiovascular Institute at the University of Pittsburgh Medical Center, 200 Lothrop Street, Pittsburgh, PA 15213, USA
    Echocardiography 23:750-5. 2006
    ....
  11. doi request reprint Utility of right ventricular tissue Doppler imaging: correlation with right heart catheterization
    Navin Rajagopalan
    Cardiovascular Institute, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania 15513 2582, USA
    Echocardiography 25:706-11. 2008
    ..The objective of this study was to correlate tissue Doppler imaging of the right ventricle (RV) with pulmonary hemodynamics in patients referred for right heart catheterization...
  12. doi request reprint Identifying left ventricular dysfunction in pulmonary hypertension
    Navin Rajagopalan
    Cardiovascular Institute, University of Pittsburgh Medical Center, PA 15213 2582, USA
    Congest Heart Fail 15:218-21. 2009
    ..01). Patients with PH demonstrate abnormal LV function as quantified by elevated LV MPI, which correlates significantly with pulmonary vascular resistance and cardiac index...
  13. ncbi request reprint An abnormal right ventricular apical angle is indicative of global right ventricular impairment
    Angel Lopez-Candales
    Cardiovascular Institute, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania 15213 2582, USA
    Echocardiography 23:361-8. 2006
    ....
  14. doi request reprint Chronic pulmonary hypertension shortens the duration of mitral annular systolic and diastolic tissue Doppler signals
    Angel Lopez-Candales
    Cardiovascular Institute, University of Pittsburgh, Scaife 560, 200 Lothrop Street, Pittsburgh, PA 15213 2582, USA
    Int J Cardiovasc Imaging 28:513-9. 2012
    ..Whether this is a result of altered LV geometry and/or confounded by the presence of relatively faster heart rates in cPH patients will require further study...
  15. doi request reprint Apical systolic eccentricity index: a better marker of right ventricular compromise in pulmonary hypertension
    Angel Lopez-Candales
    Cardiovascular Institute, University of Pittsburgh, Scaife 560, 200 Lothrop Street, Pittsburgh, PA 15213 2582, USA
    Echocardiography 27:534-8. 2010
    ..However, this measurement does not take into account the remodeling that occurs in the right ventricle (RV) during chronic pulmonary hypertension (cPH)...
  16. ncbi request reprint Right ventricular dyssynchrony in heart failure: a tissue Doppler imaging study
    Navin Rajagopalan
    Cardiovascular Institute, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania 15213 2582, USA
    J Card Fail 12:263-7. 2006
    ..We used tissue Doppler imaging to determine whether right ventricular dyssynchrony is also present in HF patients...
  17. ncbi request reprint Correlation of tricuspid annular velocities with invasive hemodynamics in pulmonary hypertension
    Navin Rajagopalan
    Cardiovascular Institute, University of Pittsburgh Medical Center, Pittsburgh, PA 15213 2582, USA
    Congest Heart Fail 13:200-4. 2007
    ..0 L/min/m2 with 89% sensitivity and 87% specificity. In conclusion, tissue Doppler imaging of the tricuspid annulus is a complementary method to assess right ventricular function in pulmonary hypertensive patients...
  18. ncbi request reprint Relation of right ventricular free wall mechanical delay to right ventricular dysfunction as determined by tissue Doppler imaging
    Angel Lopez-Candales
    Cardiovascular Institute at the University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA
    Am J Cardiol 96:602-6. 2005
    ..01) and significantly delayed time to peak strain (459 +/- 76 vs 388 +/- 29 ms, p < 0.0005) values than in healthy volunteers; a very strong correlation between RV mechanical delay and RV fractional area change (r = -0.89) was noted...
  19. pmc Tissue Doppler imaging of right ventricular decompensation in pulmonary hypertension
    Marc A Simon
    Cardiovascular Institute, University of Pittsburgh, Pittsburgh, PA 15213, USA
    Congest Heart Fail 15:271-6. 2009
    ..0001). RV free wall strain decreases in PH without hemodynamically decompensated RV function suggesting it may be a preceding step in the development of RV failure. This may be of particular use in following patients sequentially...
  20. ncbi request reprint Right ventricular systolic function is not the sole determinant of tricuspid annular motion
    Angel Lopez-Candales
    Cardiovascular Institute, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA
    Am J Cardiol 98:973-7. 2006
    ..TAPSE <2.0 cm is associated with some degree of either RV or LV dysfunction, whereas a value >2.0 cm suggests normal biventricular systolic function...
  21. ncbi request reprint Abnormal right ventricular myocardial strain generation in mild pulmonary hypertension
    Angel Lopez-Candales
    Cardiovascular Institute at the University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania 15213 2582, USA
    Echocardiography 24:615-22. 2007
    ....
  22. pmc Right ventricular dyssynchrony in patients with pulmonary hypertension is associated with disease severity and functional class
    Angel Lopez-Candales
    Cardiovascular Institute at the University of Pittsburgh Medical Center, Pittsburgh, PA, USA
    Cardiovasc Ultrasound 3:23. 2005
    ..Abnormalities in right ventricular function are known to occur in patients with pulmonary arterial hypertension...
  23. ncbi request reprint Right ventricular function following cardiac resynchronization therapy
    Navin Rajagopalan
    Cardiovascular Institute, University of Pittsburgh Medical Center, Pittsburgh, PA, USA
    Am J Cardiol 100:1434-6. 2007
    ..In conclusion, CRT resulted in improved RV function measured as RV S(m). CRT had beneficial effects on RV function independent of improvement in left ventricular ejection fraction...
  24. doi request reprint A delayed time of the peak tricuspid regurgitation signal: marker of right ventricular dysfunction
    Angel Lopez-Candales
    Cardiovascular Institute, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
    Am J Med Sci 336:224-9. 2008
    ..Worsening degrees of tricuspid regurgitation (TR) have been associated with worse outcomes. We investigated the time it takes for the TR jet to attain its maximum peak (tmpTR) with measures of right ventricular (RV) function...
  25. ncbi request reprint Large atrial appendage thrombus in the presence of severe mitral regurgitation: contradictory hemodynamics or expected findings
    Angel Lopez-Candales
    Cardiovascular Institute at the University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania 15213, USA
    Echocardiography 21:625-9. 2004
    ..However, additional confounding factors could have acted as potential mechanisms to enhance thrombosis in this setting and consequently are discussed...
  26. doi request reprint Ratio of right to left ventricular ejection: a pilot study using Doppler to detect interventricular dyssynchrony
    Angel Lopez-Candales
    Cardiovascular Institute at the University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania 15213 2582, USA
    Clin Cardiol 34:366-71. 2011
    ..However, alterations between RV and left ventricular (LV) ejection should be easily identified during routine echocardiographic examinations...
  27. doi request reprint The effect of chronic pulmonary hypertension on diastolic annular tissue velocities: a pilot study
    Angel Lopez-Candales
    Cardiovascular Institute, Division of Cardiology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
    Am J Med Sci 341:344-9. 2011
    ..However, the effect of chronic elevations in pulmonary artery systolic pressure (PASP) on individual diastolic annular velocities has not been well characterized...
  28. doi request reprint Evidence of robust coupling of atrioventricular mechanical function of the right side of the heart: insights from M-mode analysis of annular motion
    Raveen Bazaz
    Cardiovascular Institute at the University of Pittsburgh, Pittsburgh, Pennsylvania 15213 2582, USA
    Echocardiography 25:557-61. 2008
    ..However, whether any relationship exists between annular ascent and descent components remains uninvestigated...
  29. ncbi request reprint Identifying right ventricular dysfunction with tissue Doppler imaging in pulmonary hypertension
    Navin Rajagopalan
    Cardiovascular Institute, University of Pittsburgh Medical Center, Pittsburgh, PA 15213 2582, USA
    Int J Cardiol 128:359-63. 2008
    ..Standard echocardiographic assessment of right ventricular (RV) function is problematic due to the complex RV geometry. We used tissue Doppler imaging to identify RV dysfunction in patients with pulmonary hypertension (PH)...
  30. doi request reprint Right ventricular outflow tract spectral signal: a useful marker of right ventricular systolic performance and pulmonary hypertension severity
    Angel Lopez-Candales
    Cardiovascular Institute, University of Pittsburgh Medical Center, Scaife 560, 200 Lothrop Street, Pittsburgh, PA 15213 2582, USA
    Eur J Echocardiogr 11:509-15. 2010
    ..Right ventricular outflow tract (RVOT) acceleration shortens with chronic pulmonary hypertension (cPH). However, the overall value of this spectral Doppler signal in the assessment of PH patients is not well understood...
  31. pmc Unusual echocardiographic features seen in a case of giant cell myocarditis
    Minisha Kochar
    Department of Medicine, University of Pittsburgh, Pennsylvania, USA
    Can J Cardiol 24:855-6. 2008
    ..Treatment with methylprednisolone and cyclosporine was promptly initiated. Several apical clots were noted during treatment, but the patient attained full recovery with treatment...
  32. doi request reprint Altered early left ventricular diastolic wall velocities in pulmonary hypertension: a tissue Doppler study
    Angel Lopez-Candales
    Cardiovascular Institute, University of Pittsburgh, Pittsburgh, Pennsylvania 15213 2582, USA
    Echocardiography 26:1159-66. 2009
    ..Left ventricular diastolic dysfunction (LVDD) is known to occur in severe chronic pulmonary hypertension (PH); however, the mechanism(s) remains unclear...
  33. doi request reprint Normal parameters of right ventricular mechanics with exertion in healthy individuals: a tissue Doppler imaging study
    Michael Curren
    Cardiovascular Institute, University of Pittsburgh, Pennsylvania 15213 2582, USA
    Am J Med Sci 341:23-7. 2011
    ..This study attempts to determine RV mechanics at rest and immediately after exercise in healthy subjects using TDI and to define normal values...
  34. doi request reprint Pulmonary hypertension affects left ventricular basal twist: a novel use for speckle-tracking imaging
    Gautam V Ramani
    Cardiovascular Institute at the University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania 15213 2582, USA
    Echocardiography 26:44-51. 2009
    ..Chronic pulmonary hypertension (PH) results in right ventricular (RV) mechanical dyssynchrony. However, its effects on left ventricular (LV) mechanics have not been examined...
  35. doi request reprint Normal range of mechanical variables in pulmonary hypertension: a tissue Doppler imaging study
    Angel Lopez-Candales
    Cardiovascular Institute, University of Pittsburgh, Pittsburgh, Pennsylvania 15213 2582, USA
    Echocardiography 25:864-72. 2008
    ..However, to what extent these mechanical properties are expected to identify RV dysfunction in PH patients is less clear...
  36. ncbi request reprint Impact of body mass index on markers of left ventricular thickness and mass calculation: results of a pilot analysis
    Ranjini Krishnan
    Department of Medicine, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA
    Echocardiography 22:203-10. 2005
    ..Accordingly, we investigated if a particular correlation exists between BMI and echocardiographic markers of ventricular function...
  37. ncbi request reprint Elevated brain natriuretic peptide and troponin I in a woman with generalized weakness and chest pain
    Joanne Simpson
    Department of Medicine, University of Pittsburgh Medical Center, Presbyterian Hospital, Pittsburgh, Pennsylvania, USA
    Echocardiography 22:267-71. 2005
    ..We reviewed the literature regarding the use of echocardiography and the clinical significance of abnormal cardiac markers in patients presenting pulmonary embolism...
  38. doi request reprint Differences in the duration of total ejection between right and left ventricles in chronic pulmonary hypertension
    Angel Lopez-Candales
    Cardiovascular Institute, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania 15213 2582, USA
    Echocardiography 28:509-15. 2011
    ....
  39. doi request reprint New annular tissue Doppler markers of pulmonary hypertension
    Angel Lopez-Candales
    Cardiovascular Institute, University of Pittsburgh, 200 Lothrop Street, Pittsburgh, PA 15213 2582, USA
    Echocardiography 27:969-76. 2010
    ..However, the effect of chronic pulmonary hypertension (cPH) on these TDI annular events has not been well described...
  40. doi request reprint Right ventricular apical contractility in acute pulmonary embolism: the McConnell sign revisited
    Angel Lopez-Candales
    Cardiovascular Institute at the University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania 15213 2582, USA
    Echocardiography 27:614-20. 2010
    ....
  41. pmc An unusual clinical presentation resembling superior vena cava syndrome post heart surgery
    Angel Lopez-Candales
    Cardiothoracic Division, Department of Surgery, The Cardiovascular Institute, University of Pittsburgh Medical Center, Pittsburgh, PA, USA
    Cardiovasc Ultrasound 3:31. 2005
    ....
  42. doi request reprint Role of baseline echocardiography in the preoperative management of liver transplant candidates
    Matthew E Harinstein
    Heart and Vascular Institute, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA
    Am J Cardiol 110:1852-5. 2012
    ..Based on these findings, patients should not be excluded from consideration for LT based solely on the presence of an ICS or PH...
  43. ncbi request reprint Continuing medical education activity in echocardiography
    Pohoey Fan
    Cardiovascular Institute at the University of Pittsburgh Medical Center, Pittsburgh, PA University of Puerto Rico, Rio Piedras, Puerto Rico
    Echocardiography 28:508. 2011
    ..Article Title: Differences in the Duration of Total Ejection between Right and Left Ventricles in Chronic Pulmonary Hypertension (Echocardiography 2011;28:508)...
  44. doi request reprint Noninvasive estimation of pulmonary vascular resistance in pulmonary hypertension
    Navin Rajagopalan
    Cardiovascular Institute, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA
    Echocardiography 26:489-94. 2009
    ..Determination of pulmonary vascular resistance (PVR) in patients with suspected or known pulmonary hypertension (PH) requires right heart catheterization. Our purpose was to use Doppler echocardiography to estimate PVR in patients with PH...
  45. doi request reprint Constrictive-like physiology in severe pulmonary hypertension: the effect of the Valsalva maneuver
    Angel Lopez-Candales
    Cardiovascular Institute, University of Pittsburgh, Pittsburgh, PA 15213 2582, USA
    South Med J 104:282-4. 2011
    ..The clinical relevance of this finding and the pathophysiologic implications are reviewed and discussed...
  46. ncbi request reprint Atypical echocardiographic findings of endocarditis in an immunocompromised patient
    Dustin P Letts
    Cardiovascular Institute, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania 15213, USA
    Echocardiography 21:715-9. 2004
    ..This case report illustrates atypical echocardiographic manifestations of endocarditis and paravalvular abscess in an immunocompromised patient...
  47. pmc Coronary artery to left ventricle fistula
    Angel Lopez-Candales
    Cardiovascular Institute, University of Pittsburgh Medical Center, Pittsburgh, PA, USA
    Cardiovasc Ultrasound 3:35. 2005
    ..Coronary cameral fistulas are an uncommon entity, the etiology of which may be congenital or traumatic. They involve abnormal termination of a coronary artery, usually the right coronary, into a cardiac chamber, usually the right ventricle...
  48. doi request reprint Chronic pulmonary hypertension causes significant interventricular spatiotemporal dyssynchrony when onset of diastolic flow signals are assessed by color m-mode
    Angel Lopez-Candales
    Division of Cardiovascular Diseases at the University of Cincinnati, Cincinnati, Ohio 45267 0542, USA
    Echocardiography 29:653-60. 2012
    ..The spatiotemporal resolution of CMM offers a unique opportunity to study the effect of chronic pulmonary hypertension (cPH) on biventricular diastolic function...