Ning Liu

Summary

Affiliation: University of Texas Southwestern Medical Center
Country: USA

Publications

  1. doi request reprint Regulation of skeletal muscle development and disease by microRNAs
    Ning Liu
    Department of Molecular Biology, University of Texas Southwestern Medical Center, Dallas, TX, 75390, USA
    Results Probl Cell Differ 56:165-90. 2015
  2. pmc microRNA-206 promotes skeletal muscle regeneration and delays progression of Duchenne muscular dystrophy in mice
    Ning Liu
    Department of Molecular Biology, University of Texas Southwestern Medical Center, Dallas, Texas 75390 9148, USA
    J Clin Invest 122:2054-65. 2012
  3. pmc Mice lacking microRNA 133a develop dynamin 2–dependent centronuclear myopathy
    Ning Liu
    Department of Molecular Biology and 2Department of Pathology, University of Texas Southwestern Medical Center, Dallas, Texas 75930 9148, USA
    J Clin Invest 121:3258-68. 2011
  4. pmc microRNA-133a regulates cardiomyocyte proliferation and suppresses smooth muscle gene expression in the heart
    Ning Liu
    Department of Molecular Biology, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA
    Genes Dev 22:3242-54. 2008
  5. pmc Requirement of MEF2A, C, and D for skeletal muscle regeneration
    Ning Liu
    Departments of Molecular Biology, Internal Medicine, and Pathology, University of Texas Southwestern Medical Center, Dallas, TX 75390
    Proc Natl Acad Sci U S A 111:4109-14. 2014
  6. pmc Control of mitochondrial metabolism and systemic energy homeostasis by microRNAs 378 and 378*
    Michele Carrer
    Department of Molecular Biology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA
    Proc Natl Acad Sci U S A 109:15330-5. 2012
  7. pmc MicroRNA control of muscle development and disease
    Andrew H Williams
    Department of Molecular Biology, University of Texas Southwestern Medical Center, 6000 Harry Hines Blvd, Dallas, TX 75390, USA
    Curr Opin Cell Biol 21:461-9. 2009
  8. pmc An intragenic MEF2-dependent enhancer directs muscle-specific expression of microRNAs 1 and 133
    Ning Liu
    Departments of Molecular Biology and Pathology, University of Texas Southwestern Medical Center, Dallas, TX 75390 9148, USA
    Proc Natl Acad Sci U S A 104:20844-9. 2007
  9. pmc MicroRNA regulatory networks in cardiovascular development
    Ning Liu
    Department of Molecular Biology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA
    Dev Cell 18:510-25. 2010
  10. pmc Severe muscle wasting and denervation in mice lacking the RNA-binding protein ZFP106
    Douglas M Anderson
    Department of Molecular Biology, University of Texas Southwestern Medical Center, Dallas, TX 75390 Hamon Center for Regenerative Science and Medicine, University of Texas Southwestern Medical Center, Dallas, TX 75390 Senator Paul D Wellstone Muscular Dystrophy Cooperative Research Center, University of Texas Southwestern Medical Center, Dallas, TX 75390
    Proc Natl Acad Sci U S A 113:E4494-E4503. 2016

Collaborators

  • Eric N Olson
  • Rhonda Bassel-Duby
  • Eva van Rooij
  • Matthew W Hulver
  • Hui Li
  • Mauro Giacca
  • Jonathan Graff
  • Chad E Grueter
  • Douglas M Anderson
  • Kelli J Carroll
  • Andrew H Williams
  • John McAnally
  • Mayssa H Mokalled
  • Mark E Hatley
  • Jamie L Russell
  • Michele Carrer
  • Catherine A Makarewich
  • Lorena Zentilin
  • Benjamin R Nelson
  • Kelly M Anderson
  • Yun Liu
  • Jessica Cannavino
  • Svetlana Bezprozvannaya
  • Weichun Lin
  • Beibei Chen
  • Bercin K Cenik
  • Sean C Goetsch
  • Hector R Aguilar
  • Madlyn I Frisard
  • Douglas P Millay
  • Wei Tang
  • Xiang Luo
  • Doug E Frantz
  • Rene L Galindo
  • Matthew R Garcia
  • David Finkelstein
  • Helen Coe
  • Jay W Schneider

Detail Information

Publications17

  1. doi request reprint Regulation of skeletal muscle development and disease by microRNAs
    Ning Liu
    Department of Molecular Biology, University of Texas Southwestern Medical Center, Dallas, TX, 75390, USA
    Results Probl Cell Differ 56:165-90. 2015
    ....
  2. pmc microRNA-206 promotes skeletal muscle regeneration and delays progression of Duchenne muscular dystrophy in mice
    Ning Liu
    Department of Molecular Biology, University of Texas Southwestern Medical Center, Dallas, Texas 75390 9148, USA
    J Clin Invest 122:2054-65. 2012
    ..Our findings reveal an essential role for miR-206 in satellite cell differentiation during skeletal muscle regeneration and indicate that miR-206 slows progression of Duchenne muscular dystrophy...
  3. pmc Mice lacking microRNA 133a develop dynamin 2–dependent centronuclear myopathy
    Ning Liu
    Department of Molecular Biology and 2Department of Pathology, University of Texas Southwestern Medical Center, Dallas, Texas 75930 9148, USA
    J Clin Invest 121:3258-68. 2011
    ..Our findings reveal an essential role for miR-133a in the maintenance of adult skeletal muscle structure, function, bioenergetics, and myofiber identity; they also identify a potential modulator of centronuclear myopathies...
  4. pmc microRNA-133a regulates cardiomyocyte proliferation and suppresses smooth muscle gene expression in the heart
    Ning Liu
    Department of Molecular Biology, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA
    Genes Dev 22:3242-54. 2008
    ....
  5. pmc Requirement of MEF2A, C, and D for skeletal muscle regeneration
    Ning Liu
    Departments of Molecular Biology, Internal Medicine, and Pathology, University of Texas Southwestern Medical Center, Dallas, TX 75390
    Proc Natl Acad Sci U S A 111:4109-14. 2014
    ..These findings reveal essential and redundant roles of MEF2A, C, and D in satellite cell differentiation and identify a MEF2-dependent transcriptome associated with skeletal muscle regeneration. ..
  6. pmc Control of mitochondrial metabolism and systemic energy homeostasis by microRNAs 378 and 378*
    Michele Carrer
    Department of Molecular Biology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA
    Proc Natl Acad Sci U S A 109:15330-5. 2012
    ..Thus, these miRNAs provide potential targets for pharmacologic intervention in obesity and metabolic syndrome...
  7. pmc MicroRNA control of muscle development and disease
    Andrew H Williams
    Department of Molecular Biology, University of Texas Southwestern Medical Center, 6000 Harry Hines Blvd, Dallas, TX 75390, USA
    Curr Opin Cell Biol 21:461-9. 2009
    ..We review findings that point to the importance of microRNA-mediated control of gene expression during muscle development and disease, and consider the potential of microRNAs as therapeutic targets...
  8. pmc An intragenic MEF2-dependent enhancer directs muscle-specific expression of microRNAs 1 and 133
    Ning Liu
    Departments of Molecular Biology and Pathology, University of Texas Southwestern Medical Center, Dallas, TX 75390 9148, USA
    Proc Natl Acad Sci U S A 104:20844-9. 2007
    ....
  9. pmc MicroRNA regulatory networks in cardiovascular development
    Ning Liu
    Department of Molecular Biology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA
    Dev Cell 18:510-25. 2010
    ..We discuss the roles of miRNAs as regulators of cardiac form and function, unresolved questions in the field, and issues for the future...
  10. pmc Severe muscle wasting and denervation in mice lacking the RNA-binding protein ZFP106
    Douglas M Anderson
    Department of Molecular Biology, University of Texas Southwestern Medical Center, Dallas, TX 75390 Hamon Center for Regenerative Science and Medicine, University of Texas Southwestern Medical Center, Dallas, TX 75390 Senator Paul D Wellstone Muscular Dystrophy Cooperative Research Center, University of Texas Southwestern Medical Center, Dallas, TX 75390
    Proc Natl Acad Sci U S A 113:E4494-E4503. 2016
    ..These findings reveal a central role for Zfp106 in the maintenance of nerve-muscle signaling, and highlight the involvement of aberrant RNA processing in neuromuscular disease pathogenesis...
  11. pmc DNA binding-dependent and -independent functions of the Hand2 transcription factor during mouse embryogenesis
    Ning Liu
    Department of Molecular Biology, University of Texas Southwestern Medical Center, 6000 Harry Hines Boulevard, Dallas, TX 75390 9148, USA
    Development 136:933-42. 2009
    ..These findings suggest that Hand2 regulates tissue growth and development in vivo through DNA binding-dependent and -independent mechanisms...
  12. pmc A mouse model for adult cardiac-specific gene deletion with CRISPR/Cas9
    Kelli J Carroll
    Department of Molecular Biology and the Hamon Center for Regenerative Science and Medicine, University of Texas Southwestern Medical Center, Dallas, TX 75390 9148
    Proc Natl Acad Sci U S A 113:338-43. 2016
    ..This method will be useful for disease modeling and provides a means of rapidly editing genes of interest in the heart. ..
  13. pmc Myocardin-related transcription factors are required for cardiac development and function
    Mayssa H Mokalled
    Department of Molecular Biology, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390, United States
    Dev Biol 406:109-16. 2015
    ..Together, these findings demonstrate redundant but essential roles of the MRTFs in maintenance of cardiac structure and function and as indispensible links in cardiac cytoskeletal gene regulatory networks. ..
  14. pmc A mouse model of rhabdomyosarcoma originating from the adipocyte lineage
    Mark E Hatley
    Department of Molecular Biology, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390, USA
    Cancer Cell 22:536-46. 2012
    ..Our findings suggest that adipocyte progenitors can be a cell of origin for Sonic hedgehog-driven ERMS, showing that RMS can originate from nonskeletal muscle precursors...
  15. pmc A signature pattern of stress-responsive microRNAs that can evoke cardiac hypertrophy and heart failure
    Eva van Rooij
    Department of Molecular Biology, University of Texas Southwestern Medical Center, Dallas, TX 75390 9148, USA
    Proc Natl Acad Sci U S A 103:18255-60. 2006
    ....
  16. doi request reprint MicroRNAs flex their muscles
    Eva van Rooij
    Department of Molecular Biology, University of Texas Southwestern Medical Center, Dallas, TX 75390 9148, USA
    Trends Genet 24:159-66. 2008
    ..The myriad roles of microRNAs in muscle biology pose interesting prospects for their therapeutic manipulation in muscle disease...
  17. pmc Regulated expression of pH sensing G Protein-coupled receptor-68 identified through chemical biology defines a new drug target for ischemic heart disease
    Jamie L Russell
    Departments of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas, USA
    ACS Chem Biol 7:1077-83. 2012
    ....