Qing Lin

Summary

Affiliation: University of Texas Medical Branch
Country: USA

Publications

  1. pmc Regulation of AMPA receptors in spinal nociception
    Yun Wang
    Department of Anesthesiology, Beijing Chaoyang Hospital, Capital Medical University, Beijing 100020, PR China
    Mol Pain 6:5. 2010
  2. pmc Effects of general anesthetics on visceral pain transmission in the spinal cord
    Yun Wang
    Department of Anesthesiology, Beijing Chaoyang Hospital, Capital Medical University, Beijing, PR China
    Mol Pain 4:50. 2008
  3. pmc Roles of TRPV1 and neuropeptidergic receptors in dorsal root reflex-mediated neurogenic inflammation induced by intradermal injection of capsaicin
    Qing Lin
    Department of Neuroscience and Cell Biology, The University of Texas Medical Branch, Galveston, Texas 77555 1069, USA
    Mol Pain 3:30. 2007
  4. ncbi request reprint Involvement of peripheral neuropeptide Y receptors in sympathetic modulation of acute cutaneous flare induced by intradermal capsaicin
    Q Lin
    Department of Anatomy and Neuroscience, Marine Biomedical Institute, The University of Texas Medical Branch, 301 University Boulevard, Galveston, TX 77555 1069, USA
    Neuroscience 123:337-47. 2004
  5. ncbi request reprint Sympathetic modulation of acute cutaneous flare induced by intradermal injection of capsaicin in anesthetized rats
    Qing Lin
    Department of Anatomy and Neurosciences, Marine Biomedical Institute, The University of Texas Medical Branch, Texas 77555 1069, USA
    J Neurophysiol 89:853-61. 2003
  6. pmc Sensitization of primary afferent nociceptors induced by intradermal capsaicin involves the peripheral release of calcitonin gene-related Peptide driven by dorsal root reflexes
    Dingge Li
    Department of Neuroscience and Cell Biology, University of Texas Medical Branch, Galveston, Texas 77555 1069, USA
    J Pain 9:1155-68. 2008
  7. pmc The effects of sympathetic outflow on upregulation of vanilloid receptors TRPV(1) in primary afferent neurons evoked by intradermal capsaicin
    Xijin Xu
    Department of Neuroscience and Cell Biology, University of Texas Medical Branch, Galveston, TX 77555, USA
    Exp Neurol 222:93-107. 2010
  8. ncbi request reprint Sympathetic modulation of activity in Adelta- and C-primary nociceptive afferents after intradermal injection of capsaicin in rats
    Yong Ren
    Department of Neuroscience and Cell Biology, The University of Texas Medical Branch, 301 University Blvd, Galveston, TX 77555 1069, USA
    J Neurophysiol 93:365-77. 2005
  9. ncbi request reprint Effect of protein kinase C blockade on phosphorylation of NR1 in dorsal horn and spinothalamic tract cells caused by intradermal capsaicin injection in rats
    Xiaoju Zou
    Department of Anatomy and Neurosciences, Marine Biomedical Institute, The University of Texas Medical Branch, Galveston, TX 77555 1069, USA
    Brain Res 1020:95-105. 2004
  10. pmc Increases in transient receptor potential vanilloid-1 mRNA and protein in primary afferent neurons stimulated by protein kinase C and their possible role in neurogenic inflammation
    Xijin Xu
    Department of Neuroscience and Cell Biology, University of Texas Medical Branch, Galveston, Texas 77555 1069, USA
    J Neurosci Res 87:482-94. 2009

Collaborators

  • Jing Wu
  • Peng Wang
  • Jing Wang
  • Junfa Li
  • Xuan Zhang
  • Y Ren
  • W D Willis
  • Li Fang
  • Xiaoju Zou
  • Xijin Xu
  • Yun Wang
  • Dingge Li
  • Rui Qing Sun
  • Nada B Lawand
  • Yun Yue
  • Susan M Carlton
  • Jingzhen Song
  • Sandra Valencia-de Ita
  • Xiaomin Shi
  • Kerui Gong
  • Zhiguo Wu
  • Huai Yu Tan
  • Gregory L Hargett
  • Junhui Du
  • Ammar Yamani
  • Anne C Bopp
  • Claire E Hulsebosch
  • Olivera Nesic
  • Hj Nauta
  • Changcheng Yin
  • Zhong Zhang
  • Jinhua Piao
  • Hualiang Huang
  • Gilberto Castaneda-Hernandez
  • Chun Lei
  • Xiangbin Wang
  • Tiean Xia
  • Yixin Song
  • Guobing Xu
  • Yi Jun Tu
  • Jing Yin Yan

Detail Information

Publications25

  1. pmc Regulation of AMPA receptors in spinal nociception
    Yun Wang
    Department of Anesthesiology, Beijing Chaoyang Hospital, Capital Medical University, Beijing 100020, PR China
    Mol Pain 6:5. 2010
    ....
  2. pmc Effects of general anesthetics on visceral pain transmission in the spinal cord
    Yun Wang
    Department of Anesthesiology, Beijing Chaoyang Hospital, Capital Medical University, Beijing, PR China
    Mol Pain 4:50. 2008
    ..This would help elucidate the mechanism of antivisceral nociception by general anesthetics at the cellular and molecular levels and aid in development of novel therapeutic strategies to improve clinical management of visceral pain...
  3. pmc Roles of TRPV1 and neuropeptidergic receptors in dorsal root reflex-mediated neurogenic inflammation induced by intradermal injection of capsaicin
    Qing Lin
    Department of Neuroscience and Cell Biology, The University of Texas Medical Branch, Galveston, Texas 77555 1069, USA
    Mol Pain 3:30. 2007
    ..However, no direct evidence demonstrates that the release of inflammatory substances is due to the triggering of DRRs and how activation of TRPV1 receptors initiates neurogenic inflammation via triggering DRRs...
  4. ncbi request reprint Involvement of peripheral neuropeptide Y receptors in sympathetic modulation of acute cutaneous flare induced by intradermal capsaicin
    Q Lin
    Department of Anatomy and Neuroscience, Marine Biomedical Institute, The University of Texas Medical Branch, 301 University Boulevard, Galveston, TX 77555 1069, USA
    Neuroscience 123:337-47. 2004
    ..Both substances are involved, at least in part, in modulation of the responses of CAP sensitive afferents thereby affecting their ability to evoke the release of inflammatory agents from primary afferents...
  5. ncbi request reprint Sympathetic modulation of acute cutaneous flare induced by intradermal injection of capsaicin in anesthetized rats
    Qing Lin
    Department of Anatomy and Neurosciences, Marine Biomedical Institute, The University of Texas Medical Branch, Texas 77555 1069, USA
    J Neurophysiol 89:853-61. 2003
    ..Peripheral alpha(1)-adrenoceptors thus modulate the ability of capsaicin sensitive afferents to evoke the release of inflammatory agents from primary afferents by DRRs...
  6. pmc Sensitization of primary afferent nociceptors induced by intradermal capsaicin involves the peripheral release of calcitonin gene-related Peptide driven by dorsal root reflexes
    Dingge Li
    Department of Neuroscience and Cell Biology, University of Texas Medical Branch, Galveston, Texas 77555 1069, USA
    J Pain 9:1155-68. 2008
    ..Capsaicin injection evoked increases in numbers of single and double labeled TRPV(1) and CGRP neurons in ipsilateral dorsal root ganglia (DRG). After dorsal rhizotomy, these evoked expressions were significantly inhibited...
  7. pmc The effects of sympathetic outflow on upregulation of vanilloid receptors TRPV(1) in primary afferent neurons evoked by intradermal capsaicin
    Xijin Xu
    Department of Neuroscience and Cell Biology, University of Texas Medical Branch, Galveston, TX 77555, USA
    Exp Neurol 222:93-107. 2010
    ..Thus, this study proposes a potential new mechanism of sympathetic modulation of neurogenic inflammation...
  8. ncbi request reprint Sympathetic modulation of activity in Adelta- and C-primary nociceptive afferents after intradermal injection of capsaicin in rats
    Yong Ren
    Department of Neuroscience and Cell Biology, The University of Texas Medical Branch, 301 University Blvd, Galveston, TX 77555 1069, USA
    J Neurophysiol 93:365-77. 2005
    ....
  9. ncbi request reprint Effect of protein kinase C blockade on phosphorylation of NR1 in dorsal horn and spinothalamic tract cells caused by intradermal capsaicin injection in rats
    Xiaoju Zou
    Department of Anatomy and Neurosciences, Marine Biomedical Institute, The University of Texas Medical Branch, Galveston, TX 77555 1069, USA
    Brain Res 1020:95-105. 2004
    ..Combined with our previous findings, these results strongly suggest that NR1 subunits in spinal dorsal horn neurons are phosphorylated following CAP injection, and this phosphorylation is catalyzed by PKC, as well as by PKA...
  10. pmc Increases in transient receptor potential vanilloid-1 mRNA and protein in primary afferent neurons stimulated by protein kinase C and their possible role in neurogenic inflammation
    Xijin Xu
    Department of Neuroscience and Cell Biology, University of Texas Medical Branch, Galveston, Texas 77555 1069, USA
    J Neurosci Res 87:482-94. 2009
    ..Thus, up-regulation of TRPV(1) receptors in DRG neurons seems critical for initiating acute neurogenic inflammation...
  11. ncbi request reprint Protein kinases regulate the phosphorylation of the GluR1 subunit of AMPA receptors of spinal cord in rats following noxious stimulation
    Li Fang
    Division of Neurosurgery, Department of Surgery, The University of Texas Medical Branch, Galveston, TX 77555 1069, USA
    Brain Res Mol Brain Res 118:160-5. 2003
    ....
  12. ncbi request reprint Calcitonin gene-related peptide receptor activation produces PKA- and PKC-dependent mechanical hyperalgesia and central sensitization
    Rui Qing Sun
    Department of Neuroscience and Cell Biology, The University of Texas Medical Branch, 301 University Blvd, Galveston, Texas 77555 1069, USA
    J Neurophysiol 92:2859-66. 2004
    ....
  13. ncbi request reprint Involvement of peripheral purinoceptors in sympathetic modulation of capsaicin-induced sensitization of primary afferent fibers
    Yong Ren
    Department of Neuroscience and Cell Biology, University of Texas Medical Branch, 301 University Blvd, Galveston, TX 77555 1069, USA
    J Neurophysiol 96:2207-16. 2006
    ..Combined with our previous study, our data also provide further evidence that the sensitization of primary afferent nociceptors is subject to sympathetic modulation by activation of P2X as well as alpha(1)-adrenergic receptors...
  14. ncbi request reprint Calcium/calmodulin dependent protein kinase II regulates the phosphorylation of cyclic AMP-responsive element-binding protein of spinal cord in rats following noxious stimulation
    Li Fang
    Division of Neurosurgery, Department of Surgery, The University of Texas Medical Branch, Galveston, TX 77555 1069, USA
    Neurosci Lett 374:1-4. 2005
    ..These results suggest that increased phosphorylation of CREB protein may contribute to central sensitization following acute peripheral noxious stimuli, and the effect may be regulated through the activation of CaM kinase cascades...
  15. pmc Peripheral and central sensitization in remote spinal cord regions contribute to central neuropathic pain after spinal cord injury
    Susan M Carlton
    Department of Neuroscience and Cell Biology, University of Texas Medical Branch, Galveston, TX 77555 1069, USA
    Pain 147:265-76. 2009
    ..We hypothesize that reactive glia in the cervical cord release pro-inflammatory substances which drive chronic CNP. Thus a complex cascade of events spanning many cord segments underlies above-level CNP...
  16. ncbi request reprint Sympathetic influence on capsaicin-evoked enhancement of dorsal root reflexes in rats
    Jing Wang
    Dept of Anatomy and Neuroscience, The Univ of Texas Medical Branch, 301 University Blvd, Galveston, TX 77555 1069, USA
    J Neurophysiol 92:2017-26. 2004
    ....
  17. ncbi request reprint Role of calcitonin gene-related peptide in the sensitization of dorsal horn neurons to mechanical stimulation after intradermal injection of capsaicin
    Rui Qing Sun
    Department of Neuroscience and Cell Biology, The University of Texas Medical Branch, 301 University Blvd, Galveston, TX 77555 1069, USA
    J Neurophysiol 92:320-6. 2004
    ..The effect could be blocked by CGRP(8-37) dose-dependently. Collectively, these results suggest that CGRP and its receptors are involved in the spinal cord central sensitization induced by intradermal injection of capsaicin...
  18. ncbi request reprint The effects of sympathectomy on capsaicin-evoked fos expression of spinal dorsal horn GABAergic neurons
    Xiaoju Zou
    Department of Anatomy and Neuroscience, Marine Biomedical Institute, The University of Texas Medical Branch, Galveston, TX 77555 1069, USA
    Brain Res 958:322-9. 2002
    ....
  19. ncbi request reprint Effects of protein kinase a activation on the responses of primate spinothalamic tract neurons to mechanical stimuli
    Qing Lin
    Department of Anatomy and Neurosciences, Marine Biomedical Institute, The University of Texas Medical Branch, Galveston, Texas 77555 1069, USA
    J Neurophysiol 88:214-21. 2002
    ..We speculate that the PKA signal transduction cascade may contribute more to secondary mechanical hyperalgesia than to secondary mechanical allodynia...
  20. ncbi request reprint Calcium-calmodulin-dependent protein kinase II contributes to spinal cord central sensitization
    Li Fang
    Department of Anatomy and Neurosciences, Marine Biomedical Institute, The University of Texas Medical Branch, Galveston, Texas 77555 1069, USA
    J Neurosci 22:4196-204. 2002
    ..This study reveals that CaMK II contributes to central sensitization in a manner similar to its role in the processes underlying long-term potentiation...
  21. ncbi request reprint Signal transduction in chronic pain
    Jing Wu
    The University of Texas Medical Branch, Galveston, Texas, USA
    Int Anesthesiol Clin 45:73-81. 2007
  22. pmc The role of c-AMP-dependent protein kinase in spinal cord and post synaptic dorsal column neurons in a rat model of visceral pain
    Jing Wu
    Department of Neurology, University of Texas Health Science Center, Houston, TX 77030, United States
    Neurochem Int 50:710-8. 2007
    ..The results of our study suggest that the PKA signal transduction cascade may contribute to visceral nociceptive changes in spinal PSDC pathways...
  23. ncbi request reprint Role of the Na+-K+-2Cl- cotransporter in the development of capsaicin-induced neurogenic inflammation
    Sandra Valencia-de Ita
    Seccion Externa de Farmacologia, Centro de Investigacion y de Estudios Avanzados del Instituto Politecnico Nacional, Mexico, DF Mexico
    J Neurophysiol 95:3553-61. 2006
    ..Taken together these results suggest that NKCC is involved in the increases in DRR activity, neurogenic inflammation and hyperalgesia and allodynia induced by intradermal CAP...
  24. ncbi request reprint Fusion of chemotactic peptide to a single-chain bi-specific antibody (scBsAb) potentiates its cytotoxicity to target tumour cells
    Jingzhen Song
    Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Datun Road, Beijing 100101, People s Republic of China
    Biotechnol Appl Biochem 45:147-54. 2006
    ..The results indicated that fusion of chemotactic peptide to BsAb potentiated its cytotoxicity to tumour cells in vitro. It suggests that 18TBHL may be a promising candidate agent in cancer immunotherapy...
  25. ncbi request reprint N-terminal-pro-B-type natriuretic peptide (NT-proBNP): reference range for Chinese apparently healthy people and clinical performance in Chinese elderly patients with heart failure
    Xiaomin Shi
    Department of Medicine Laboratory, Peking University First Hospital, 8 Xi Shi Ku Street, Beijing 100034, PR China
    Clin Chim Acta 360:122-7. 2005
    ..We established a reference range for Chinese apparently healthy people based on age and gender and evaluated the clinical performance of NT-proBNP in the diagnosis of asymptomatic and symptomatic HF...