Jue Lin

Summary

Affiliation: University of California
Country: USA

Publications

  1. pmc Analyses and comparisons of telomerase activity and telomere length in human T and B cells: insights for epidemiology of telomere maintenance
    Jue Lin
    Department of Biochemistry and Biophysics, University of California, San Francisco, San Francisco, CA 94143, United States
    J Immunol Methods 352:71-80. 2010
  2. doi request reprint Telomeres and lifestyle factors: roles in cellular aging
    Jue Lin
    University of California, San Francisco, CA 94158, USA
    Mutat Res 730:85-9. 2012
  3. ncbi request reprint Cell aging in relation to stress arousal and cardiovascular disease risk factors
    Elissa S Epel
    UCSF Department of Psychiatry, San Francisco, CA, USA
    Psychoneuroendocrinology 31:277-87. 2006
  4. pmc Stress appraisals and cellular aging: a key role for anticipatory threat in the relationship between psychological stress and telomere length
    Aoife O'Donovan
    Department of Psychiatry, University of California, San Francisco, CA, USA
    Brain Behav Immun 26:573-9. 2012
  5. pmc Dynamics of telomerase activity in response to acute psychological stress
    Elissa S Epel
    Department of Psychiatry, University of California, San Francisco, 3333 Calif St, Suite 465, San Francisco, CA 94143, USA
    Brain Behav Immun 24:531-9. 2010
  6. pmc Dietary restraint and telomere length in pre- and postmenopausal women
    Amy Kiefer
    UCSF Department of Psychiatry, University of California, San Francisco, California, USA
    Psychosom Med 70:845-9. 2008
  7. pmc Telomere length trajectory and its determinants in persons with coronary artery disease: longitudinal findings from the heart and soul study
    Ramin Farzaneh-Far
    Division of Cardiology, San Francisco General Hospital, San Francisco, California, USA
    PLoS ONE 5:e8612. 2010
  8. pmc Childhood trauma associated with short leukocyte telomere length in posttraumatic stress disorder
    Aoife O'Donovan
    Department of Psychiatry, University of California, San Francisco, California Northern California Institute for Research and Education, San Francisco, California, USA
    Biol Psychiatry 70:465-71. 2011
  9. pmc Changes in stress, eating, and metabolic factors are related to changes in telomerase activity in a randomized mindfulness intervention pilot study
    JENNIFER DAUBENMIER
    Osher Center for Integrative Medicine, Department of Medicine, University of California, San Francisco, CA, USA
    Psychoneuroendocrinology 37:917-28. 2012
  10. pmc Leukocyte telomere length predicts SSRI response in major depressive disorder: A preliminary report
    Christina M Hough
    Department of Psychiatry, University of California San Francisco UCSF School of Medicine, San Francisco, CA, USA
    Mol Neuropsychiatry 2:88-96. 2016

Collaborators

Detail Information

Publications32

  1. pmc Analyses and comparisons of telomerase activity and telomere length in human T and B cells: insights for epidemiology of telomere maintenance
    Jue Lin
    Department of Biochemistry and Biophysics, University of California, San Francisco, San Francisco, CA 94143, United States
    J Immunol Methods 352:71-80. 2010
    ..55, r<0.001), indicating possible common mechanisms for telomerase activity regulation in these two cell subtypes. These data will facilitate the understanding of leukocyte aging and its relationship to human health...
  2. doi request reprint Telomeres and lifestyle factors: roles in cellular aging
    Jue Lin
    University of California, San Francisco, CA 94158, USA
    Mutat Res 730:85-9. 2012
    ..Lastly, we propose possible biochemical mechanisms that mediate these associations and discuss future directions...
  3. ncbi request reprint Cell aging in relation to stress arousal and cardiovascular disease risk factors
    Elissa S Epel
    UCSF Department of Psychiatry, San Francisco, CA, USA
    Psychoneuroendocrinology 31:277-87. 2006
    ..These findings may implicate telomerase as a novel and important mediator of the effects of psychological stress on physical health and disease...
  4. pmc Stress appraisals and cellular aging: a key role for anticipatory threat in the relationship between psychological stress and telomere length
    Aoife O'Donovan
    Department of Psychiatry, University of California, San Francisco, CA, USA
    Brain Behav Immun 26:573-9. 2012
    ..Exaggerated anticipatory threat appraisals may be a common and modifiable psychological mechanism of psychological stress effects on cellular aging...
  5. pmc Dynamics of telomerase activity in response to acute psychological stress
    Elissa S Epel
    Department of Psychiatry, University of California, San Francisco, 3333 Calif St, Suite 465, San Francisco, CA 94143, USA
    Brain Behav Immun 24:531-9. 2010
    ....
  6. pmc Dietary restraint and telomere length in pre- and postmenopausal women
    Amy Kiefer
    UCSF Department of Psychiatry, University of California, San Francisco, California, USA
    Psychosom Med 70:845-9. 2008
    ....
  7. pmc Telomere length trajectory and its determinants in persons with coronary artery disease: longitudinal findings from the heart and soul study
    Ramin Farzaneh-Far
    Division of Cardiology, San Francisco General Hospital, San Francisco, California, USA
    PLoS ONE 5:e8612. 2010
    ..We sought to investigate the longitudinal trajectory of telomere length, and to identify the independent predictors of telomere shortening, in persons with coronary artery disease...
  8. pmc Childhood trauma associated with short leukocyte telomere length in posttraumatic stress disorder
    Aoife O'Donovan
    Department of Psychiatry, University of California, San Francisco, California Northern California Institute for Research and Education, San Francisco, California, USA
    Biol Psychiatry 70:465-71. 2011
    ..We also examined childhood trauma, a risk factor for both PTSD and short LTL, as a potential contributor to short LTL in PTSD...
  9. pmc Changes in stress, eating, and metabolic factors are related to changes in telomerase activity in a randomized mindfulness intervention pilot study
    JENNIFER DAUBENMIER
    Osher Center for Integrative Medicine, Department of Medicine, University of California, San Francisco, CA, USA
    Psychoneuroendocrinology 37:917-28. 2012
    ....
  10. pmc Leukocyte telomere length predicts SSRI response in major depressive disorder: A preliminary report
    Christina M Hough
    Department of Psychiatry, University of California San Francisco UCSF School of Medicine, San Francisco, CA, USA
    Mol Neuropsychiatry 2:88-96. 2016
    ..Our data suggest that short LTL may serve as a vulnerability index of poorer response to SSRI treatment, but this needs examination in larger samples...
  11. pmc Tired telomeres: Poor global sleep quality, perceived stress, and telomere length in immune cell subsets in obese men and women
    Aric A Prather
    Department of Psychiatry, University of California, San Francisco, United States Electronic address
    Brain Behav Immun 47:155-62. 2015
    ..These findings provide preliminary evidence that poorer global sleep quality is related to telomere length in several immune cell types, which may serve as a pathway linking sleep and disease risk in obese individuals. ..
  12. pmc Maternal estriol concentrations in early gestation predict infant telomere length
    Sonja Entringer
    Departments of Pediatrics S E, C B, P D W, Obstetrics and Gynecology P D W, Epidemiology P D W, and Psychiatry and Human Behavior P D W, University of California, Irvine California 92697 Department of Obstetrics, Gynecology, and Reproductive Sciences H N S, University of Pittsburgh, Pittsburgh, Pennsylvania 15213 Departments of Psychiatry E S E, and Biochemistry and Biophysics E H B, University of California, San Francisco, San Francisco, California 94143 and Institute for Medical Psychology S E, C B, Charite University Medicine, 10117 Berlin, Germany
    J Clin Endocrinol Metab 100:267-73. 2015
    ..The initial setting of telomere length (TL) in early life has important implications for telomere maintenance and related disorders throughout the life span. However, little is known about the predictors of this initial setting...
  13. pmc Maternal psychosocial stress during pregnancy is associated with newborn leukocyte telomere length
    Sonja Entringer
    Department of Pediatrics, University of California, Irvine, School of Medicine, Irvine, CA 92697, USA
    Am J Obstet Gynecol 208:134.e1-7. 2013
    ..The objective of the present study was to determine how early in life this effect of stress on LTL is apparent by quantifying the association of maternal psychosocial stress during pregnancy with newborn telomere length...
  14. pmc Greater endogenous estrogen exposure is associated with longer telomeres in postmenopausal women at risk for cognitive decline
    Jue Lin
    Department of Biochemistry and Biophysics, University of California, San Francisco, CA 94118, USA
    Brain Res 1379:224-31. 2011
    ..The results suggest that the endogenous estrogens may be associated with deceleration of cellular aging. This is the first study to examine associations between endogenous estrogens, telomere length and telomerase activity...
  15. pmc Systematic and Cell Type-Specific Telomere Length Changes in Subsets of Lymphocytes
    Jue Lin
    Department of Biochemistry and Biophysics, University of California San Francisco, San Francisco, CA 94143, USA
    J Immunol Res 2016:5371050. 2016
    ..These results suggest systematically coordinated, yet cell type-specific responses to factors and pathways contribute to telomere length regulation. ..
  16. pmc Association between kidney function and telomere length: the heart and soul study
    Nisha Bansal
    Department of Medicine, University of California, San Francisco, USA
    Am J Nephrol 36:405-11. 2012
    ..Telomere attrition is a novel risk factor for cardiovascular disease. Studies of telomere length in relation to kidney function are limited. We explored the association of kidney function with telomere length and telomere shortening...
  17. doi request reprint Increased telomerase activity and comprehensive lifestyle changes: a pilot study
    Dean Ornish
    Department of Medicine, University of California, San Francisco, CA, USA
    Lancet Oncol 9:1048-57. 2008
    ..We aimed to assess whether 3 months of intensive lifestyle changes increased telomerase activity in peripheral blood mononuclear cells (PBMC)...
  18. pmc Telomere shortening in formerly abused and never abused women
    Janice Humphreys
    Department of Family Health Care Nursing, School of Nursing, University of California, San Francisco, CA 94143, USA
    Biol Res Nurs 14:115-23. 2012
    ..Findings from this descriptive study suggest a link between IPV exposure, duration of IPV-related stress, and telomere length molecular mechanisms that regulate cellular aging...
  19. pmc The power of exercise: buffering the effect of chronic stress on telomere length
    Eli Puterman
    Department of Psychiatry, University of California San Francisco, San Francisco, California, USA
    PLoS ONE 5:e10837. 2010
    ..We predicted that chronic stress would be related to short telomere length (TL) in sedentary individuals, whereas in those who exercise, stress would not have measurable effects on telomere shortening...
  20. pmc Association of marine omega-3 fatty acid levels with telomeric aging in patients with coronary heart disease
    Ramin Farzaneh-Far
    Division of Cardiology, Room 5G1, San Francisco General Hospital, 1001 Potrero Ave, San Francisco, CA 94110, USA
    JAMA 303:250-7. 2010
    ..Increased dietary intake of marine omega-3 fatty acids is associated with prolonged survival in patients with coronary heart disease. However, the mechanisms underlying this protective effect are poorly understood...
  21. pmc Leukocyte telomere length and mortality in the National Health and Nutrition Examination Survey, 1999-2002
    Belinda L Needham
    From the aDepartment of Epidemiology and Center for Social Epidemiology and Population Health, University of Michigan, Ann Arbor, MI bDivision of General Medical Disciplines, Stanford University, Stanford, CA cDepartment of Psychiatry, dDivision of General Internal Medicine, and eDepartment of Biochemistry and Biophysics, University of California, San Francisco, CA
    Epidemiology 26:528-35. 2015
    ..We also examined moderating effects of age, sex, race/ethnicity, and education...
  22. pmc Associations of ghrelin with eating behaviors, stress, metabolic factors, and telomere length among overweight and obese women: preliminary evidence of attenuated ghrelin effects in obesity?
    Julia Buss
    University of California, San Francisco, School of Nursing, United States
    Appetite 76:84-94. 2014
    ..Furthermore, ghrelin is associated with metabolic and cardiovascular health, and may have anti-aging effects, but these effects may be attenuated in obesity. ..
  23. pmc Chronic stress elevates telomerase activity in rats
    Annaliese K Beery
    Robert Wood Johnson Health and Society Scholar at University of California at San Francisco, San Francisco, CA 04143, USA
    Biol Lett 8:1063-6. 2012
    ..This significant increase suggests a potential mechanism for resilience to stress-related replicative senescence...
  24. pmc Shorter leukocyte telomere length in midlife women with poor sleep quality
    Aric A Prather
    Robert Wood Johnson Foundation Health and Society Scholars Program, Center for Health and Community, University of California San Francisco, 3333 California Street, Suite 465, San Francisco, CA 94118, USA
    J Aging Res 2011:721390. 2011
    ..Conclusions. This study provides the first evidence that poor sleep quality explains significant variation in LTL, a marker of cellular aging...
  25. pmc Stress exposure in intrauterine life is associated with shorter telomere length in young adulthood
    Sonja Entringer
    Department of Pediatrics, University of California, Irvine, CA 92697, USA
    Proc Natl Acad Sci U S A 108:E513-8. 2011
    ..This observation may help shed light on an important biological pathway underlying the developmental origins of adult health and disease risk...
  26. pmc Soda and cell aging: associations between sugar-sweetened beverage consumption and leukocyte telomere length in healthy adults from the National Health and Nutrition Examination Surveys
    Cindy W Leung
    Cindy W Leung is with the Center for Health and Community, School of Medicine, University of California, San Francisco Barbara A Laraia is with the School of Public Health, University of California, Berkeley Belinda Needham is with the Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor David H Rehkopf is with the Department of Medicine, Stanford University, Palo Alto, CA Nancy E Adler and Elissa S Epel are with the Center for Health and Community and the Department of Psychiatry, School of Medicine, University of California, San Francisco Jue Lin and Elizabeth H Blackburn are with the Department of Biochemistry and Biophysics, University of California, San Francisco
    Am J Public Health 104:2425-31. 2014
    ..We tested whether leukocyte telomere length maintenance, which underlies healthy cellular aging, provides a link between sugar-sweetened beverage (SSB) consumption and the risk of cardiometabolic disease...
  27. doi request reprint Telomere length change plateaus at 4 years of age in Latino children: associations with baseline length and maternal change
    Janet M Wojcicki
    Department of Pediatrics, University of California, San Francisco, San Francisco, CA, USA
    Mol Genet Genomics 291:1379-89. 2016
    ..While some of this shared variance is genetic, there are likely environmental factors that need to be further identified that impact rate of telomere length change. ..
  28. doi request reprint Human telomere biology: A contributory and interactive factor in aging, disease risks, and protection
    Elizabeth H Blackburn
    Department of Biochemistry and Biophysics, University of California, San Francisco, CA 94143, USA
    Science 350:1193-8. 2015
    ..These and other recent findings highlight both causal and potentiating roles for telomere attrition in human diseases. ..
  29. doi request reprint Leukocyte telomere length: Effects of schizophrenia, age, and gender
    Owen M Wolkowitz
    University of California San Francisco School of Medicine UCSF, San Francisco, CA, USA
    J Psychiatr Res 85:42-48. 2016
    ..One putative marker of biological aging is leukocyte telomere length (LTL), which typically shortens with age...
  30. pmc Automated Assay of Telomere Length Measurement and Informatics for 100,000 Subjects in the Genetic Epidemiology Research on Adult Health and Aging (GERA) Cohort
    Kyle Lapham
    Department of Biochemistry and Biophysics, University of California, San Francisco, California 94158 2517
    Genetics 200:1061-72. 2015
    ..The GERA cohort represents the largest currently available such resource, linked to comprehensive electronic health and genotype data for analysis. ..
  31. pmc Psychiatric disorders and leukocyte telomere length: Underlying mechanisms linking mental illness with cellular aging
    Daniel Lindqvist
    Department of Clinical Sciences, Section for Psychiatry, Lund University, Lund, Sweden Department of Psychiatry, University of California San Francisco UCSF, School of Medicine, San Francisco, CA, USA
    Neurosci Biobehav Rev 55:333-64. 2015
    ..A deeper understanding of cellular aging in psychiatric illnesses could lead to re-conceptualizing them as systemic illnesses with manifestations inside and outside the brain and could identify new treatment targets. ..
  32. pmc Accelerated telomere shortening in response to life stress
    Elissa S Epel
    Department of Psychiatry, University of California, 3333 California Street, Suite 465, San Francisco, CA 94143, USA
    Proc Natl Acad Sci U S A 101:17312-5. 2004
    ..These findings have implications for understanding how, at the cellular level, stress may promote earlier onset of age-related diseases...