Wei Liao

Summary

Affiliation: University of California
Country: USA

Publications

  1. ncbi request reprint Knockdown of apolipoprotein B, an atherogenic apolipoprotein, in HepG2 cells by lentivirus-mediated siRNA
    Wei Liao
    Department of Medicine, Division of Endocrinology and Metabolism, University of California, San Diego, La Jolla, CA 92093, USA
    Biochem Biophys Res Commun 344:478-83. 2006
  2. ncbi request reprint Proteasome inhibition induces differential heat shock protein response but not unfolded protein response in HepG2 cells
    Wei Liao
    The Department of Medicine, Division of Endocrinology and Metabolism, University of California San Diego School of Medicine, La Jolla, California 92093 0673, USA
    J Cell Biochem 99:1085-95. 2006
  3. ncbi request reprint Suppression of PPAR-gamma attenuates insulin-stimulated glucose uptake by affecting both GLUT1 and GLUT4 in 3T3-L1 adipocytes
    Wei Liao
    Department of Medicine, Division of Endocrinology and Metabolism, University of California, San Diego, La Jolla, CA 92093, USA
    Am J Physiol Endocrinol Metab 293:E219-27. 2007
  4. ncbi request reprint Ubiquitin-dependent and -independent proteasomal degradation of apoB associated with endoplasmic reticulum and Golgi apparatus, respectively, in HepG2 cells
    Wei Liao
    The Section of Endocrinology and Metabolism, Department of Medicine, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030 3498, USA
    J Cell Biochem 89:1019-29. 2003
  5. ncbi request reprint Lentiviral short hairpin ribonucleic acid-mediated knockdown of GLUT4 in 3T3-L1 adipocytes
    Wei Liao
    Department of Medicine, Division of Endocrinology and Metabolism, University of California, San Diego, La Jolla, 92093, USA
    Endocrinology 147:2245-52. 2006
  6. pmc Cellular determinants of hepatitis C virus assembly, maturation, degradation, and secretion
    Pablo Gastaminza
    The Scripps Research Institute, Maildrop SBR 10, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA
    J Virol 82:2120-9. 2008
  7. ncbi request reprint Blocking microsomal triglyceride transfer protein interferes with apoB secretion without causing retention or stress in the ER
    Wei Liao
    Mammalian Cell and Molecular Biology Laboratory, San Diego State University, San Diego, CA 92182 4614, USA
    J Lipid Res 44:978-85. 2003
  8. pmc Cloning of apoB intrabodies: specific knockdown of apoB in HepG2 cells
    Wei Liao
    Department of Medicine and Molecular and Cellular Biology, Baylor College of Medicine, St Luke s Episcopal Hospital, Houston, TX, USA
    Biochem Biophys Res Commun 373:235-40. 2008

Detail Information

Publications8

  1. ncbi request reprint Knockdown of apolipoprotein B, an atherogenic apolipoprotein, in HepG2 cells by lentivirus-mediated siRNA
    Wei Liao
    Department of Medicine, Division of Endocrinology and Metabolism, University of California, San Diego, La Jolla, CA 92093, USA
    Biochem Biophys Res Commun 344:478-83. 2006
    ..Our studies indicate that lentiviral siRNAs provide an excellent approach for delivering siRNA into HepG2 cells and may be used for gene therapy for hyperlipidemia...
  2. ncbi request reprint Proteasome inhibition induces differential heat shock protein response but not unfolded protein response in HepG2 cells
    Wei Liao
    The Department of Medicine, Division of Endocrinology and Metabolism, University of California San Diego School of Medicine, La Jolla, California 92093 0673, USA
    J Cell Biochem 99:1085-95. 2006
    ..Our study also suggests that HSPs play important roles in directing proteasomal degradation and protein aggregate formation...
  3. ncbi request reprint Suppression of PPAR-gamma attenuates insulin-stimulated glucose uptake by affecting both GLUT1 and GLUT4 in 3T3-L1 adipocytes
    Wei Liao
    Department of Medicine, Division of Endocrinology and Metabolism, University of California, San Diego, La Jolla, CA 92093, USA
    Am J Physiol Endocrinol Metab 293:E219-27. 2007
    ....
  4. ncbi request reprint Ubiquitin-dependent and -independent proteasomal degradation of apoB associated with endoplasmic reticulum and Golgi apparatus, respectively, in HepG2 cells
    Wei Liao
    The Section of Endocrinology and Metabolism, Department of Medicine, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030 3498, USA
    J Cell Biochem 89:1019-29. 2003
    ....
  5. ncbi request reprint Lentiviral short hairpin ribonucleic acid-mediated knockdown of GLUT4 in 3T3-L1 adipocytes
    Wei Liao
    Department of Medicine, Division of Endocrinology and Metabolism, University of California, San Diego, La Jolla, 92093, USA
    Endocrinology 147:2245-52. 2006
    ..These studies indicate that lentiviral shRNA constructs provide an excellent approach to deliver functional siRNAs into 3T3-L1 adipocytes for studying insulin signaling and adipocyte biology...
  6. pmc Cellular determinants of hepatitis C virus assembly, maturation, degradation, and secretion
    Pablo Gastaminza
    The Scripps Research Institute, Maildrop SBR 10, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA
    J Virol 82:2120-9. 2008
    ..These results suggest that by coopting the VLDL assembly, maturation, degradation, and secretory machinery of the cell, HCV acquires its hepatocyte tropism and, by mimicry, its tendency to persist...
  7. ncbi request reprint Blocking microsomal triglyceride transfer protein interferes with apoB secretion without causing retention or stress in the ER
    Wei Liao
    Mammalian Cell and Molecular Biology Laboratory, San Diego State University, San Diego, CA 92182 4614, USA
    J Lipid Res 44:978-85. 2003
    ..The rapid degradation of secretion-incompetent apoB in the ER may block the induction of proteins associated with unfolded protein and heat shock responses...
  8. pmc Cloning of apoB intrabodies: specific knockdown of apoB in HepG2 cells
    Wei Liao
    Department of Medicine and Molecular and Cellular Biology, Baylor College of Medicine, St Luke s Episcopal Hospital, Houston, TX, USA
    Biochem Biophys Res Commun 373:235-40. 2008
    ..This study demonstrates the utility of an intrabody to specifically block the secretion of a protein determinant of plasma LDL as a therapeutic strategy for the treatment of hyperlipidemia...