Milton Levin

Summary

Affiliation: University of Connecticut
Country: USA

Publications

  1. doi request reprint Immunomodulatory effects of exposure to polychlorinated biphenyls and perfluoroalkyl acids in East Greenland ringed seals (Pusa hispida)
    Milton Levin
    Department of Pathobiology and Veterinary Science, University of Connecticut, 61 North Eagleville Road, Storrs, CT 06269 3089, United States Electronic address
    Environ Res 151:244-250. 2016
  2. doi request reprint Validation of a commercial canine assay kit to measure pinniped cytokines
    Milton Levin
    Department of Pathobiology and Veterinary Science, University of Connecticut, 61 North Eagleville Road, Storrs, CT 06269 3089, United States Center for Environmental Sciences and Engineering, University of Connecticut, 3107 Horsebarn Hill Road, Storrs, CT 06269 4210, United States Electronic address
    Vet Immunol Immunopathol 160:90-6. 2014
  3. ncbi request reprint Specific non-coplanar PCB-mediated modulation of bottlenose dolphin and beluga whale phagocytosis upon in vitro exposure
    Milton Levin
    Department of Pathobiology and Veterinary Science, University of Connecticut, Storrs, Connecticut 06269, USA
    J Toxicol Environ Health A 67:1517-35. 2004
  4. ncbi request reprint Immunomodulatory effects upon in vitro exposure of California sea lion and southern sea otter peripheral blood leukocytes to domoic acid
    Milton Levin
    Department of Pathobiology and Veterinary Science, University of Connecticut, 61 North, Eagleville Road, U 3089, Storrs, Connecticut 06269, USA
    J Wildl Dis 46:541-50. 2010
  5. pmc Immunomodulatory effects of domoic acid differ between in vivo and in vitro exposure in mice
    Milton Levin
    Department of Pathobiology and Veterinary Science, University of Connecticut, Storrs, CT 06269, USA
    Mar Drugs 6:636-59. 2008
  6. ncbi request reprint Immunomodulatory effects of organochlorine mixtures upon in vitro exposure of peripheral blood leukocytes differ between free-ranging and captive southern sea otters (Enhydra lutris)
    Milton Levin
    Department of Pathobiology and Veterinary Science, University of Connecticut, 61 North Eagleville Road, U 89 Storrs, CT 06269, USA
    Vet Immunol Immunopathol 119:269-77. 2007
  7. ncbi request reprint Non-coplanar PCBs induce calcium mobilization in bottlenose dolphin and beluga whale, but not in mouse leukocytes
    Milton Levin
    Department of Pathobiology and Veterinary Science, University of Connecticut, Storrs, Connecticut 06269, USA
    J Toxicol Environ Health A 70:1220-31. 2007
  8. ncbi request reprint Modulation of the respiratory burst by organochlorine mixtures in marine mammals, humans, and mice
    Milton Levin
    Department of Pathobiology and Veterinary Science, University of Connecticut, Storrs, Connecticut 06269, USA
    J Toxicol Environ Health A 70:73-83. 2007
  9. ncbi request reprint Non-coplanar PCB-mediated modulation of human leukocyte phagocytosis: a new mechanism for immunotoxicity
    Milton Levin
    Department of Pathobiology and Veterinary Science, University of Connecticut, Storrs, Connecticut 06269, USA
    J Toxicol Environ Health A 68:1977-93. 2005
  10. ncbi request reprint Association between lymphocyte proliferation and polychlorinated biphenyls in free-ranging harbor seal (Phoca vitulina) pups from British Columbia, Canada
    Milton Levin
    Department of Pathobiology and Veterinary Science, University of Connecticut, 61 North Eagleville Road, U 89, Storrs, Connecticut 06269, USA
    Environ Toxicol Chem 24:1247-52. 2005

Collaborators

Detail Information

Publications15

  1. doi request reprint Immunomodulatory effects of exposure to polychlorinated biphenyls and perfluoroalkyl acids in East Greenland ringed seals (Pusa hispida)
    Milton Levin
    Department of Pathobiology and Veterinary Science, University of Connecticut, 61 North Eagleville Road, Storrs, CT 06269 3089, United States Electronic address
    Environ Res 151:244-250. 2016
    ..Taken together, these data suggest this population of ringed seals is not currently at high risk of altered lymphocyte proliferation from exposure to the POPs or PFASs in this study...
  2. doi request reprint Validation of a commercial canine assay kit to measure pinniped cytokines
    Milton Levin
    Department of Pathobiology and Veterinary Science, University of Connecticut, 61 North Eagleville Road, Storrs, CT 06269 3089, United States Center for Environmental Sciences and Engineering, University of Connecticut, 3107 Horsebarn Hill Road, Storrs, CT 06269 4210, United States Electronic address
    Vet Immunol Immunopathol 160:90-6. 2014
    ..g. physical examination, hematology, and serum chemistry. ..
  3. ncbi request reprint Specific non-coplanar PCB-mediated modulation of bottlenose dolphin and beluga whale phagocytosis upon in vitro exposure
    Milton Levin
    Department of Pathobiology and Veterinary Science, University of Connecticut, Storrs, Connecticut 06269, USA
    J Toxicol Environ Health A 67:1517-35. 2004
    ..This is the first report demonstrating the immunomodulatory effects of OCs on dolphin and beluga phagocytosis, and the first overall demonstration of immunomodulatory effects on phagocytosis mediated specifically by non-coplanar PCBs...
  4. ncbi request reprint Immunomodulatory effects upon in vitro exposure of California sea lion and southern sea otter peripheral blood leukocytes to domoic acid
    Milton Levin
    Department of Pathobiology and Veterinary Science, University of Connecticut, 61 North, Eagleville Road, U 3089, Storrs, Connecticut 06269, USA
    J Wildl Dis 46:541-50. 2010
    ....
  5. pmc Immunomodulatory effects of domoic acid differ between in vivo and in vitro exposure in mice
    Milton Levin
    Department of Pathobiology and Veterinary Science, University of Connecticut, Storrs, CT 06269, USA
    Mar Drugs 6:636-59. 2008
    ..Modulation of cytosolic calcium suggests that DA exerts its effects through ionotropic glutamate subtype surface receptors at least on monocytes. This study is the first to identify DA as an immunotoxic chemical in a mammalian species...
  6. ncbi request reprint Immunomodulatory effects of organochlorine mixtures upon in vitro exposure of peripheral blood leukocytes differ between free-ranging and captive southern sea otters (Enhydra lutris)
    Milton Levin
    Department of Pathobiology and Veterinary Science, University of Connecticut, 61 North Eagleville Road, U 89 Storrs, CT 06269, USA
    Vet Immunol Immunopathol 119:269-77. 2007
    ..Understanding differences in toxicity to different populations of sea otters will have important implications for risk assessment as well as conservation and management strategies...
  7. ncbi request reprint Non-coplanar PCBs induce calcium mobilization in bottlenose dolphin and beluga whale, but not in mouse leukocytes
    Milton Levin
    Department of Pathobiology and Veterinary Science, University of Connecticut, Storrs, Connecticut 06269, USA
    J Toxicol Environ Health A 70:1220-31. 2007
    ..These results demonstrate for the first time the direct effects of non-coplanar PCBs on Ca2+ mobilization in marine mammals, which may be involved in the modulation of phagocytosis previously observed in these species...
  8. ncbi request reprint Modulation of the respiratory burst by organochlorine mixtures in marine mammals, humans, and mice
    Milton Levin
    Department of Pathobiology and Veterinary Science, University of Connecticut, Storrs, Connecticut 06269, USA
    J Toxicol Environ Health A 70:73-83. 2007
    ..Elucidating the relative sensitivities to the immunomodulatory effects of OC mixtures between different species may have important implications for risk assessment as well as conservation and management strategies...
  9. ncbi request reprint Non-coplanar PCB-mediated modulation of human leukocyte phagocytosis: a new mechanism for immunotoxicity
    Milton Levin
    Department of Pathobiology and Veterinary Science, University of Connecticut, Storrs, Connecticut 06269, USA
    J Toxicol Environ Health A 68:1977-93. 2005
    ..Our results are cause for concern as they suggest an AhR-independent pathway through which non-coplanar PCBs modulate phagocytosis, the immune system's first line of defense, possibly increasing the risk to developing infectious disease...
  10. ncbi request reprint Association between lymphocyte proliferation and polychlorinated biphenyls in free-ranging harbor seal (Phoca vitulina) pups from British Columbia, Canada
    Milton Levin
    Department of Pathobiology and Veterinary Science, University of Connecticut, 61 North Eagleville Road, U 89, Storrs, Connecticut 06269, USA
    Environ Toxicol Chem 24:1247-52. 2005
    ..Further research is needed to evaluate the relative roles of natural and contaminant-related influences on the immune system of marine mammals...
  11. ncbi request reprint PCBs and TCDD, alone and in mixtures, modulate marine mammal but not B6C3F1 mouse leukocyte phagocytosis
    Milton Levin
    Department of Pathobiology and Veterinary Science, University of Connecticut, Storrs, Connecticut 06269, USA
    J Toxicol Environ Health A 68:635-56. 2005
    ....
  12. doi request reprint Effects of organochlorines, individually and in mixtures, on B-cell proliferation in marine mammals and mice
    Chiharu Mori
    Department of Pathobiology and Veterinary Science, University of Connecticut, Storrs, Connecticut 06269, USA
    J Toxicol Environ Health A 71:266-75. 2008
    ..These findings may be helpful in more accurately characterizing the immunotoxic potential of OC in different target species and help in more relevant risk assessment...
  13. ncbi request reprint Immunomodulatory effects of in vitro exposure to organochlorines on T-cell proliferation in marine mammals and mice
    Chiharu Mori
    Department of Pathobiology and Veterinary Science, University of Connecticut, Storrs, Connecticut 06269, USA
    J Toxicol Environ Health A 69:283-302. 2006
    ..These findings will be useful to better characterize the risk associated with OC exposure and possibly lead to new conservation and management strategies...
  14. doi request reprint Saxitoxin increases phocine distemper virus replication upon in-vitro infection in harbor seal immune cells
    Andrea L Bogomolni
    Department of Pathobiology and Veterinary Science, University of Connecticut, 61 North Eagleville Rd, Storrs, CT 06269, USA Biology Department, Woods Hole Oceanographic Institution, Woods Hole, MA 02543, USA Electronic address
    Harmful Algae 51:89-96. 2016
    ..Given the concurrent increase in morbillivirus epizootics and HAB events in the last 25 years, the relationship between low level toxin exposure and host susceptibility to morbillivirus needs to be further explored...
  15. doi request reprint In Vitro Exposure of Harbor Seal Immune Cells to Aroclor 1260 Alters Phocine Distemper Virus Replication
    Andrea Bogomolni
    Department of Pathobiology and Veterinary Science, University of Connecticut, 61 North Eagleville Rd, Storrs, CT, 06268, USA
    Arch Environ Contam Toxicol 70:121-32. 2016
    ....