G M Leinninger
Affiliation: University of Michigan
- Location, location, location: the CNS sites of leptin action dictate its regulation of homeostatic and hedonic pathwaysG M Leinninger
Division of Metabolism, Endocrinology and Diabetes, Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, MI 48109 0678, USA
Int J Obes (Lond) 33:S14-7. 2009..Understanding the unique neuroanatomical and functional roles for each locus of leptin action will be important to identify how specific aspects of food intake contribute to obesity...
- Leptin action via neurotensin neurons controls orexin, the mesolimbic dopamine system and energy balanceGina M Leinninger
Division of Metabolism, Endocrinology, and Diabetes, Department of Internal Medicine, University of Michigan, Ann Arbor, MI 48109, USA
Cell Metab 14:313-23. 2011..Thus, LHA LepRb(Nts) neurons mediate physiologic leptin action on OX neurons and the mesolimbic DA system, and contribute importantly to the control of energy balance...
- LRb signals act within a distributed network of leptin-responsive neurones to mediate leptin actionG M Leinninger
Division of Metabolism, Endocrinology and Diabetes, Department of Medicine, University of Michigan Medical School, Ann Arbor, MI 48109 0678, USA
Acta Physiol (Oxf) 192:49-59. 2008..It will be important to define the molecular mechanisms by which leptin acts to regulate neurophysiology in each of these LRb-expressing neural populations in order to understand the totality of leptin action...