Robert D Langer

Summary

Affiliation: University of California
Country: USA

Publications

  1. ncbi request reprint Stability of electrocardiographic classification pre- and postglucose challenge
    Robert D Langer
    University of California, San Diego, Department of Family and Preventive Medicine, Division of Epidemiology, 0607, La Jolla, CA 92093 0607, USA
    Am J Epidemiol 155:577-9. 2002
  2. ncbi request reprint Relationships between symptoms and venous disease: the San Diego population study
    Robert D Langer
    Department of Family and Preventive Medicine, University of California, San Diego, La Jalla 92093 0978, USA
    Arch Intern Med 165:1420-4. 2005
  3. ncbi request reprint Baseline associations between postmenopausal hormone therapy and inflammatory, haemostatic, and lipid biomarkers of coronary heart disease. The Women's Health Initiative Observational Study
    Robert D Langer
    Department of Family and Preventive Medicine, University of California, San Diego, 9500 Gilman Drive, MC 0978, La Jolla, CA 92093 0978, USA
    Thromb Haemost 93:1108-16. 2005
  4. pmc Chronic venous disease in an ethnically diverse population: the San Diego Population Study
    Michael H Criqui
    Department of Family and Preventive Medicine, School of Medicine, University of California, San Diego, San Diego, CA 92093, USA
    Am J Epidemiol 158:448-56. 2003
  5. doi request reprint Association between different measures of blood pressure and coronary artery calcium in postmenopausal women
    Matthew A Allison
    University of California San Diego, La Jolla, California, USA
    Hypertension 52:833-40. 2008
  6. pmc Risk factors for chronic venous disease: the San Diego Population Study
    Michael H Criqui
    Department of Family and Preventive Medicine, University of California, San Diego, CA, USA
    J Vasc Surg 46:331-7. 2007
  7. ncbi request reprint Renal artery calcium: relationship to systemic calcified atherosclerosis
    Matthew A Allison
    Departments of Family and Preventive Medicine, University of California, San Diego, La Jolla, CA, USA
    Vasc Med 11:232-8. 2006
  8. pmc Vasomotor symptoms and coronary artery calcium in postmenopausal women
    Matthew A Allison
    University of California San Diego, La Jolla, CA 92093 0965, USA
    Menopause 17:1136-45. 2010
  9. ncbi request reprint Ethnicity and peripheral arterial disease: the San Diego Population Study
    Michael H Criqui
    Department of Family and Preventive Medicine, School of Medicine, University of California, San Diego, La Jolla, California, USA
    Circulation 112:2703-7. 2005
  10. doi request reprint Neighborhood Environment and Physical Activity Among Older Women: Findings From the San Diego Cohort of the Women's Health Initiative
    Jacqueline Kerr
    Dept of Family and Preventive Medicine, University of California, San Diego, San Diego, CA
    J Phys Act Health 11:1070-7. 2014

Detail Information

Publications62

  1. ncbi request reprint Stability of electrocardiographic classification pre- and postglucose challenge
    Robert D Langer
    University of California, San Diego, Department of Family and Preventive Medicine, Division of Epidemiology, 0607, La Jolla, CA 92093 0607, USA
    Am J Epidemiol 155:577-9. 2002
    ..More ECGs worsened than improved, and the variability pre- and postglucose was at least as great as that between clinic visits conducted 8 years apart...
  2. ncbi request reprint Relationships between symptoms and venous disease: the San Diego population study
    Robert D Langer
    Department of Family and Preventive Medicine, University of California, San Diego, La Jalla 92093 0978, USA
    Arch Intern Med 165:1420-4. 2005
    ..The associations between symptoms and venous disease of the lower extremities are poorly characterized...
  3. ncbi request reprint Baseline associations between postmenopausal hormone therapy and inflammatory, haemostatic, and lipid biomarkers of coronary heart disease. The Women's Health Initiative Observational Study
    Robert D Langer
    Department of Family and Preventive Medicine, University of California, San Diego, 9500 Gilman Drive, MC 0978, La Jolla, CA 92093 0978, USA
    Thromb Haemost 93:1108-16. 2005
    ..Some associations differed between women with and without incident CHD, especially for EP, where inflammatory and thrombotic markers were higher in cases. These associations remain speculative pending confirmation in randomized trials...
  4. pmc Chronic venous disease in an ethnically diverse population: the San Diego Population Study
    Michael H Criqui
    Department of Family and Preventive Medicine, School of Medicine, University of California, San Diego, San Diego, CA 92093, USA
    Am J Epidemiol 158:448-56. 2003
    ..7%, 0.6%, and 1.3% for legs visibly and functionally normal. However, visible disease did not invariably predict functional disease, or vice versa, and venous thrombotic events occurred in the absence of either...
  5. doi request reprint Association between different measures of blood pressure and coronary artery calcium in postmenopausal women
    Matthew A Allison
    University of California San Diego, La Jolla, California, USA
    Hypertension 52:833-40. 2008
    ..03 to 2.90; P=0.04). In postmenopausal women, higher levels of pulse pressure and systolic blood pressure were strong determinants of CAC, whereas diastolic blood pressure was inversely related...
  6. pmc Risk factors for chronic venous disease: the San Diego Population Study
    Michael H Criqui
    Department of Family and Preventive Medicine, University of California, San Diego, CA, USA
    J Vasc Surg 46:331-7. 2007
    ..The etiology of chronic venous disease in the lower limbs is unclear, and very limited data are available on potential risk factors from representative population studies...
  7. ncbi request reprint Renal artery calcium: relationship to systemic calcified atherosclerosis
    Matthew A Allison
    Departments of Family and Preventive Medicine, University of California, San Diego, La Jolla, CA, USA
    Vasc Med 11:232-8. 2006
    ..These relationships are independent of traditional CVD risk factors...
  8. pmc Vasomotor symptoms and coronary artery calcium in postmenopausal women
    Matthew A Allison
    University of California San Diego, La Jolla, CA 92093 0965, USA
    Menopause 17:1136-45. 2010
    ..We assessed whether vasomotor symptoms (VMS) are associated with coronary artery calcium (CAC) and how hormone therapy (HT) may influence this association...
  9. ncbi request reprint Ethnicity and peripheral arterial disease: the San Diego Population Study
    Michael H Criqui
    Department of Family and Preventive Medicine, School of Medicine, University of California, San Diego, La Jolla, California, USA
    Circulation 112:2703-7. 2005
    ..Previous studies have indicated higher rates of peripheral arterial disease (PAD) in blacks than in non-Hispanic whites (NHWs), with limited information available for Hispanics and Asians. The reason for the PAD excess in blacks is unclear...
  10. doi request reprint Neighborhood Environment and Physical Activity Among Older Women: Findings From the San Diego Cohort of the Women's Health Initiative
    Jacqueline Kerr
    Dept of Family and Preventive Medicine, University of California, San Diego, San Diego, CA
    J Phys Act Health 11:1070-7. 2014
    ..Environmental measures at different spatial levels have seldom been compared. Findings from previous studies are generally inconsistent...
  11. pmc Oophorectomy, hormone therapy, and subclinical coronary artery disease in women with hysterectomy: the Women's Health Initiative coronary artery calcium study
    Matthew A Allison
    University of California San Diego, La Jolla, CA, USA
    Menopause 15:639-47. 2008
    ..In this study, we aimed to determine the associations between coronary artery calcium (CAC) and hysterectomy, oophorectomy, and hormone therapy use with a focus on the duration of menopause for which there was no hormone therapy use...
  12. pmc Mortality related to actigraphic long and short sleep
    Daniel F Kripke
    Department of Psychiatry, University of California, San Diego, La Jolla, CA 92037, USA
    Sleep Med 12:28-33. 2011
    ..5 h or shorter than 6.5 h predicts increased mortality risk. This study examined if prospectively-determined objective sleep duration, as estimated by wrist actigraphy, was associated with mortality risks...
  13. ncbi request reprint Sex and time differences in the associations of non-high-density lipoprotein cholesterol versus other lipid and lipoprotein factors in the prediction of cardiovascular death (The Rancho Bernardo Study)
    Denise von Muhlen
    Division of Epidemiology, Department of Family and Preventive Medicine, University of California San Diego, La Jolla, CA 93093 0607, USA
    Am J Cardiol 91:1311-5. 2003
    ..Thus, non-HDL cholesterol is not superior to individual lipids, lipoproteins, or their ratios in the prediction of cardiovascular death in older adults...
  14. pmc Ethnicity, sleep, mood, and illumination in postmenopausal women
    Daniel F Kripke
    Department of Psychiatry, University of California, San Diego, CA, USA
    BMC Psychiatry 4:8. 2004
    ..This study examined how ethnic differences in sleep and depression were related to environmental illumination and circadian rhythms...
  15. ncbi request reprint Quantified duplex augmentation in healthy subjects and patients with venous disease: San Diego population study
    Arnost Fronek
    Department of Surgery, VA San Diego Healthcare System, San Diego, USA
    J Vasc Surg 37:1054-8. 2003
    ....
  16. ncbi request reprint Naps and circadian rhythms in postmenopausal women
    In Young Yoon
    Department of Psychiatry, 0667, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA 92093 0667, USA
    J Gerontol A Biol Sci Med Sci 59:844-8. 2004
    ..Napping patterns and relationships among naps, circadian rhythms, and nocturnal sleep were evaluated in postmenopausal women. Naps and nocturnal sleep were compared between depressed women and healthy volunteers...
  17. ncbi request reprint Ethnic-specific prevalence of peripheral arterial disease in the United States
    Matthew A Allison
    Department of Family and Preventive Medicine, University of California San Diego, California, USA
    Am J Prev Med 32:328-33. 2007
    ..The aim of this study was to estimate the age-, gender-, and ethnic-specific burden of PAD in the United States for the year 2000...
  18. ncbi request reprint Postmenopausal hormone therapy and migraine headache
    Anastasia L Misakian
    University of California San Diego School of Medicine, San Diego, California, USA
    J Womens Health (Larchmt) 12:1027-36. 2003
    ..No population-based studies have examined the association between hormone therapy (HT) and migraine among postmenopausal women...
  19. ncbi request reprint Bleeding patterns of the hormone replacement therapies in the postmenopausal estrogen and progestin interventions trial
    Etta A Lindenfeld
    Department of Psychiatry, University of California, San Diego, California 92037, USA
    Obstet Gynecol 100:853-63. 2002
    ..To explore whether significant differences exist between bleeding patterns with common regimens of hormone replacement therapy using two different progestogens...
  20. ncbi request reprint Atherosclerotic calcification and intimal medial thickness of the carotid arteries
    Matthew A Allison
    University of California at San Diego, 8950 Villa La Jolla Drive, Suite C203, La Jolla, CA 92037, USA
    Int J Cardiol 103:98-104. 2005
    ..The purpose of this study was to determine the significance and magnitude of association between IMT and atherosclerotic calcification of the carotid arteries...
  21. ncbi request reprint The Women's Health Initiative Observational Study: baseline characteristics of participants and reliability of baseline measures
    Robert D Langer
    Department of Family and Preventive Medicine, University of California, San Diego, La Jolla, CA 92037, USA
    Ann Epidemiol 13:S107-21. 2003
  22. pmc Light exposure is related to social and emotional functioning and to quality of life in older women
    Michael A Grandner
    Joint Doctoral Program in Clinical Psychology, San Diego State University, and University of California, San Diego, La Jolla, CA, United States
    Psychiatry Res 143:35-42. 2006
    ..Increased light exposure is related to improved quality of life and social and emotional functioning...
  23. ncbi request reprint Mitral and aortic annular calcification are highly associated with systemic calcified atherosclerosis
    Matthew A Allison
    Department of Family and Preventive Medicine, University of California San Diego, San Diego, California, USA
    Circulation 113:861-6. 2006
    ..The aim of this study was to determine whether atherosclerotic calcification in multiple vascular areas is significantly associated with aortic or mitral annular calcification independent of traditional risk factors...
  24. doi request reprint Neighborhood environment and physical activity among older women: findings from the San Diego Cohort of the women's health initiative
    Jacqueline Kerr
    Dept of Family and Preventive Medicine, University of California, San Diego, San Diego, CA
    J Phys Act Health 11:1070-7. 2014
    ..Environmental measures at different spatial levels have seldom been compared. Findings from previous studies are generally inconsistent...
  25. pmc Hypnotics' association with mortality or cancer: a matched cohort study
    Daniel F Kripke
    Scripps Clinic Viterbi Family Sleep Center, La Jolla, California, USA
    BMJ Open 2:e000850. 2012
    ..An estimated 6%-10% of US adults took a hypnotic drug for poor sleep in 2010. This study extends previous reports associating hypnotics with excess mortality...
  26. doi request reprint The Cardiovascular Research Network: a new paradigm for cardiovascular quality and outcomes research
    Alan S Go
    Kaiser Permanente Northern California, University of California, San Francisco, Calif, USA
    Circ Cardiovasc Qual Outcomes 1:138-47. 2008
    ..More robust data are also needed on how well clinical trials are translated into contemporary community practice and the associated resource use, costs, and outcomes...
  27. ncbi request reprint Depression and endogenous melatonin in postmenopausal women
    Arja Tuunainen
    Department of Psychiatry, University of California San Diego, 9500 Gilman Drive, Dept 0667, La Jolla, CA 92093 0667, USA
    J Affect Disord 69:149-58. 2002
    ..Previous reports on melatonin secretion in depression are numerous but conflicting. There are very few studies relating the duration of the nocturnal melatonin peak to depression, and the results of those studies have been equivocal...
  28. ncbi request reprint Hormone replacement and the prevention of cardiovascular disease
    Robert D Langer
    University of California at San Diego, School of Medicine, La Jolla, California 92037, USA
    Am J Cardiol 89:36E-46E; discussion 46E. 2002
    ..This information should be considered when deciding whether to use HRT in an individual woman, and if so, which formulation to use...
  29. ncbi request reprint Evening light exposure: implications for sleep and depression
    Geralyn M Wallace-Guy
    Department of Psychiatry and the Sam and Rose Stein Institute for Research on Aging, University of California San Diego, La Jolla, California 92093, USA
    J Am Geriatr Soc 50:738-9. 2002
    ..To examine whether dim illumination in the evening is a factor in sleep disturbances of aging, depression, and circadian phase advance...
  30. pmc Self-reported sleep latency in postmenopausal women
    Doo Heum Park
    Department of Psychiatry, Konkuk University School of Medicine, Seoul, Korea
    J Korean Med Sci 22:1007-14. 2007
    ..Therapeutic approaches suggested for trouble falling asleep might include increased daylight exposure, improvements in general health, and modification of anti-hypertensive pharmacotherapy...
  31. pmc Calcium plus vitamin D supplementation and the risk of incident diabetes in the Women's Health Initiative
    Ian H De Boer
    Division of Nephrology, University of Washington, 1959 NE Pacific Street, Seattle, WA 98195, USA
    Diabetes Care 31:701-7. 2008
    ..We examined the effect of calcium plus vitamin D supplementation on the incidence of drug-treated diabetes in postmenopausal women...
  32. doi request reprint Relation of demographic factors, menstrual history, reproduction and medication use to sex hormone levels in postmenopausal women
    Anne McTiernan
    Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA
    Breast Cancer Res Treat 108:217-31. 2008
    ..These results suggest that while age, oophorectomy status, and NSAID use may be associated with selected sex hormone concentrations, few menstrual or reproductive factors affect endogenous sex hormones in the postmenopausal period...
  33. ncbi request reprint Influence of estrogen plus progestin on breast cancer and mammography in healthy postmenopausal women: the Women's Health Initiative Randomized Trial
    Rowan T Chlebowski
    Harbor UCLA Research and Education Institute, Torrance 90502, USA
    JAMA 289:3243-53. 2003
    ..Outstanding issues not previously addressed include characteristics of breast cancers observed among women using hormones and whether diagnosis may be influenced by hormone effects on mammography...
  34. pmc Conjugated equine estrogens and breast cancer risk in the Women's Health Initiative clinical trial and observational study
    Ross L Prentice
    Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA 98109 1024, USA
    Am J Epidemiol 167:1407-15. 2008
    ....
  35. ncbi request reprint Estrogen plus progestin and the risk of peripheral arterial disease: the Women's Health Initiative
    Judith Hsia
    Department of Medicine, George Washington University, Washington, DC, USA
    Circulation 109:620-6. 2004
    ..This analysis evaluates clinical peripheral arterial disease among generally healthy women in the Women's Health Initiative randomized trial of estrogen plus progestin...
  36. pmc Effects of estrogen with and without progestin and obesity on symptomatic gastroesophageal reflux
    Zongli Zheng
    Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
    Gastroenterology 135:72-81. 2008
    ..An association between female hormones and symptomatic gastroesophageal reflux disease (GERD) and may be modified by obesity is suggested but not proven. Factors affecting GERD progression, however, are largely unknown...
  37. doi request reprint A prospective study of the effect of hypertension and baseline blood pressure on cognitive decline and dementia in postmenopausal women: the Women's Health Initiative Memory Study
    Karen C Johnson
    Department of Preventive Medicine, University of Tennessee Health Science Center, Memphis, Tennesse 38163, USA
    J Am Geriatr Soc 56:1449-58. 2008
    ..To examine the relationship between baseline hypertension, blood pressure, and the development of cognitive decline in participants in the Women's Health Initiative Memory Study (WHIMS)...
  38. pmc Cystatin-C, renal function, and incidence of hip fracture in postmenopausal women
    Andrea Z LaCroix
    Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109 1024, USA
    J Am Geriatr Soc 56:1434-41. 2008
    ..To evaluate the association between chronic kidney disease and incident hip fracture using serum cystatin-C as a biomarker of renal function calculated without reference to muscle mass...
  39. pmc Usefulness of baseline lipids and C-reactive protein in women receiving menopausal hormone therapy as predictors of treatment-related coronary events
    Paul F Bray
    Cardeza Foundation for Hematologic Research and Jefferson Medical College, Philadelphia, Pennsylvania, USA
    Am J Cardiol 101:1599-1605. 2008
    ..However, women with favorable lipid levels, especially LDL/HDL cholesterol ratio <2.5, did not have increased risk of coronary heart disease with CEE with or without MPA irrespective of hs-CRP...
  40. ncbi request reprint Estrogen therapy and coronary-artery calcification
    JoAnn E Manson
    Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02215, USA
    N Engl J Med 356:2591-602. 2007
    ..We examined the relationship between estrogen therapy and coronary-artery calcium in the context of a randomized clinical trial...
  41. ncbi request reprint Postmenopausal hormone therapy: critical reappraisal and a unified hypothesis
    Lawrence S Phillips
    General Clinical Research Center, Emory University Hospital, Division of Endocrinology and Metabolism, Department of Medicine, Emory University School of Medicine, Atlanta, Georgia 30322, USA
    Fertil Steril 83:558-66. 2005
    ....
  42. ncbi request reprint Low-fat dietary pattern and risk of cardiovascular disease: the Women's Health Initiative Randomized Controlled Dietary Modification Trial
    Barbara V Howard
    MedStar Research Institute Howard University, Washington, DC, USA
    JAMA 295:655-66. 2006
    ..Multiple epidemiologic studies and some trials have linked diet with cardiovascular disease (CVD) prevention, but long-term intervention data are needed...
  43. ncbi request reprint Conjugated equine estrogens and coronary heart disease: the Women's Health Initiative
    Judith Hsia
    Department of Medicine, George Washington University, Washington, DC, USA
    Arch Intern Med 166:357-65. 2006
    ..These trials did not address the role of unopposed estrogen for coronary protection...
  44. ncbi request reprint Calcium plus vitamin D supplementation and the risk of fractures
    Rebecca D Jackson
    Division of Endocrinology, Ohio State University, 485 McCampbell, 1581 Dodd Dr, Columbus, OH 43210, USA
    N Engl J Med 354:669-83. 2006
    ..The efficacy of calcium with vitamin D supplementation for preventing hip and other fractures in healthy postmenopausal women remains equivocal...
  45. ncbi request reprint Combined analysis of Women's Health Initiative observational and clinical trial data on postmenopausal hormone treatment and cardiovascular disease
    Ross L Prentice
    Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA 98109 1024, USA
    Am J Epidemiol 163:589-99. 2006
    ..An application to postmenopausal hormone treatment effects on coronary heart disease among younger women is also provided...
  46. ncbi request reprint Venous thrombosis and conjugated equine estrogen in women without a uterus
    J David Curb
    University of Hawaii and Pacific Health Research Institute, Honolulu, USA
    Arch Intern Med 166:772-80. 2006
    ..Clinical trial data on the effects of estrogen alone on VT are limited...
  47. ncbi request reprint Association between reported alcohol intake and cognition: results from the Women's Health Initiative Memory Study
    Mark A Espeland
    Department of Public Health Sciences, Wake Forest University School of Medicine, Winston Salem, NC 27157, USA
    Am J Epidemiol 161:228-38. 2005
    ..Moderate levels of alcohol intake may be associated with better cognition and reduced risk of significant cognitive decline; however, confounding associations with unmeasured factors cannot be ruled out...
  48. ncbi request reprint Tissue plasminogen activator antigen and D-dimer as markers for atherothrombotic risk among healthy postmenopausal women
    Aruna D Pradhan
    Division of Preventive Medicine, Brigham and Women s Hospital and Harvard Medical School, 900 Commonwealth Ave East, Boston, Mass 02215, USA
    Circulation 110:292-300. 2004
    ..Few studies have evaluated this relationship in women. In addition, although menopausal hormone therapy (HT) may alter markers of fibrinolytic function, the relevance of this effect for coronary risk assessment has not been studied...
  49. ncbi request reprint Effects of conjugated equine estrogen in postmenopausal women with hysterectomy: the Women's Health Initiative randomized controlled trial
    Garnet L Anderson
    Fred Hutchinson Cancer Research Center, Seattle, Wash 98109 1024, USA
    JAMA 291:1701-12. 2004
    ..Despite decades of use and considerable research, the role of estrogen alone in preventing chronic diseases in postmenopausal women remains uncertain...
  50. pmc Calcium, vitamin D supplementation, and physical function in the Women's Health Initiative
    Robert L Brunner
    University of Nevada School of Medicine, PMB 251, MS 145, Reno, NV 89557, USA
    J Am Diet Assoc 108:1472-9. 2008
    ..Now we examine whether the treatment affected self-reported physical functioning and objective measures of physical functioning...
  51. pmc Abdominal aortic aneurysm events in the women's health initiative: cohort study
    Frank A Lederle
    VA Medical Center, Minneapolis, MN 55417, USA
    BMJ 337:a1724. 2008
    ..To assess the association between potential risk factors and subsequent clinically important abdominal aortic aneurysm events (repairs and ruptures) in women...
  52. pmc Hip bone density predicts breast cancer risk independently of Gail score: results from the Women's Health Initiative
    Zhao Chen
    Division of Epidemiology and Biostatistics, University of Arizona College of Public Health, Tucson, Arizona 85724 5211, USA
    Cancer 113:907-15. 2008
    ..The objective of the current study was to investigate whether hip BMD predicts postmenopausal breast cancer risk independently of the Gail score...
  53. doi request reprint Low-fat dietary pattern and risk of treated diabetes mellitus in postmenopausal women: the Women's Health Initiative randomized controlled dietary modification trial
    Lesley F Tinker
    Women s Health Initiative, Fred Hutchinson Cancer Research Center, PO Box 19024, Mail Stop M3 A410, Seattle, WA 98109, USA
    Arch Intern Med 168:1500-11. 2008
    ..This study was undertaken to assess the effects of a low-fat dietary pattern on incidence of treated diabetes among generally healthy postmenopausal women...
  54. ncbi request reprint Calcium plus vitamin D supplementation and the risk of colorectal cancer
    Jean Wactawski-Wende
    Department of Social and Preventive Medicine, University at Buffalo, 270 Farber Hall, Buffalo, NY 14214, USA
    N Engl J Med 354:684-96. 2006
    ..However, randomized-trial evidence that calcium with vitamin D supplementation is beneficial in the primary prevention of colorectal cancer is lacking...
  55. ncbi request reprint Effects of tibolone and continuous combined conjugated equine estrogen/medroxyprogesterone acetate on the endometrium and vaginal bleeding: results of the OPAL study
    Robert D Langer
    Gesinger Health System, Danville, PA 17822 3003, USA
    Am J Obstet Gynecol 195:1320-7. 2006
    ..5 mg), continuous combined conjugated equine estrogen/medroxyprogesterone acetate [0.625/2.5 mg], and placebo on the endometrium and vaginal bleeding; these results are the subject of this report...
  56. ncbi request reprint Effects of E2 and E2/norgestimate hormone therapy on elevated baseline lipids
    Robert D Langer
    Center for Health Research and Rural Advocacy, Geisinger Health System, 100 North Academy Avenue, MC 30 03, Danville, PA 17822, USA
    J Reprod Med 51:610-6. 2006
    ..To evaluate lipid effects of estradiol/ norgestimate hormone therapy in postmenopausal women with elevated lipid levels...
  57. pmc Cardiovascular disease, its risk factors and treatment, and age-related macular degeneration: Women's Health Initiative Sight Exam ancillary study
    Ronald Klein
    Department of Ophthalmology and Visual Sciences, University of Wisconsin, Madison, Wisconsin 53726, USA
    Am J Ophthalmol 143:473-83. 2007
    ..To examine the association of cardiovascular disease (CVD), CVD risk factors, and CVD treatment with age-related macular degeneration (AMD)...
  58. ncbi request reprint Low-fat dietary pattern and risk of colorectal cancer: the Women's Health Initiative Randomized Controlled Dietary Modification Trial
    Shirley A A Beresford
    Department of Epidemiology, University of Washington, Seattle, WA 98195 7236, USA
    JAMA 295:643-54. 2006
    ..Observational studies and polyp recurrence trials are not conclusive regarding the effects of a low-fat dietary pattern on risk of colorectal cancer, necessitating a primary prevention trial...
  59. doi request reprint Estrogen plus progestin and breast cancer detection by means of mammography and breast biopsy
    Rowan T Chlebowski
    Los Angeles Biomedical Research Institute at Harbor UCLA Medical Center, Torrance, CA 90502, USA
    Arch Intern Med 168:370-7; quiz 345. 2008
    ..The effect of combined hormone therapy on breast cancer detection is not established...
  60. pmc Associations between age-related nuclear cataract and lutein and zeaxanthin in the diet and serum in the Carotenoids in the Age-Related Eye Disease Study, an Ancillary Study of the Women's Health Initiative
    Suzen M Moeller
    Department of Ophthalmology and Visual Sciences, University of Wisconsin, Madison, WI 53726 2336, USA
    Arch Ophthalmol 126:354-64. 2008
    ..To evaluate associations between nuclear cataract (determined from slitlamp photographs between May 2001 and January 2004) and lutein and zeaxanthin in the diet and serum in patients between 1994 and 1998 and macula between 2001 and 2004...
  61. ncbi request reprint Statin use and incident frailty in women aged 65 years or older: prospective findings from the Women's Health Initiative Observational Study
    Andrea Z LaCroix
    Fred Hutchinson Cancer Research Center, Seattle, WA 98109 1024, USA
    J Gerontol A Biol Sci Med Sci 63:369-75. 2008
    ..This study examines associations between current use, duration, and potency of statin medications and incident frailty in initially nonfrail women 65 years old or older...
  62. ncbi request reprint Low-fat dietary pattern and risk of invasive breast cancer: the Women's Health Initiative Randomized Controlled Dietary Modification Trial
    Ross L Prentice
    Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Wash 98109, USA
    JAMA 295:629-42. 2006
    ..The hypothesis that a low-fat dietary pattern can reduce breast cancer risk has existed for decades but has never been tested in a controlled intervention trial...