Melissa Lamar

Summary

Affiliation: University of Illinois at Chicago
Country: USA

Publications

  1. pmc Cognitive and connectome properties detectable through individual differences in graphomotor organization
    Melissa Lamar
    Department of Psychiatry, University of Illinois at Chicago, Chicago, IL 60612, United States Graduate Program in Neuroscience, University of Illinois at Chicago, Chicago, IL 60612, United States Electronic address
    Neuropsychologia 85:301-9. 2016
  2. pmc What Metabolic Syndrome Contributes to Brain Outcomes in African American & Caucasian Cohorts
    Melissa Lamar
    University of Illinois at Chicago, 1601 West Taylor Street MC912, Chicago, IL 60612, USA
    Curr Alzheimer Res 12:640-7. 2015
  3. pmc In vivo quantification of white matter microstructure for use in aging: a focus on two emerging techniques
    Melissa Lamar
    Department of Psychiatry, University of Illinois at Chicago, Chicago, IL Graduate Program in Neuroscience, University of Illinois at Chicago, Chicago, IL Electronic address
    Am J Geriatr Psychiatry 22:111-21. 2014
  4. pmc Prefrontal vulnerabilities and whole brain connectivity in aging and depression
    Melissa Lamar
    Department of Psychiatry, University of Illinois at Chicago, 1601W Taylor St, MC912, Chicago, IL 60601, USA
    Neuropsychologia 51:1463-70. 2013
  5. pmc Differential associations between types of verbal memory and prefrontal brain structure in healthy aging and late life depression
    Melissa Lamar
    Department of Psychiatry, University of Illinois at Chicago, 1601 West Taylor Street, MC912, Chicago, IL 60612, USA
    Neuropsychologia 50:1823-9. 2012
  6. doi request reprint Down syndrome with and without dementia: an in vivo proton Magnetic Resonance Spectroscopy study with implications for Alzheimer's disease
    Melissa Lamar
    Department of Psychological Medicine, Section of Brain Maturation, Institute of Psychiatry, King s College London, London, England, UK
    Neuroimage 57:63-8. 2011
  7. ncbi request reprint Serotonin and the neural processing of facial emotions in adults with autism: an fMRI study using acute tryptophan depletion
    Eileen M Daly
    Department of Forensic and Neurodevelopmental Science, Institute of Psychiatry, King s College London, London, England
    Arch Gen Psychiatry 69:1003-13. 2012
  8. pmc Quantitative tract-specific measures of uncinate and cingulum in major depression using diffusion tensor imaging
    Aifeng Zhang
    Department of Psychiatry, University of Illinois Chicago, Chicago, IL 60612, USA
    Neuropsychopharmacology 37:959-67. 2012
  9. pmc Response inhibition and serotonin in autism: a functional MRI study using acute tryptophan depletion
    Eileen Daly
    1 Sackler Institute of Translational Neurodevelopment, Department of Forensic and Neurodevelopmental Science, Institute of Psychiatry, King s College London, UK
    Brain 137:2600-10. 2014
  10. doi request reprint The impact of region-specific leukoaraiosis on working memory deficits in dementia
    Melissa Lamar
    MRC Center for Neurodegeneration, Department of Psychology Section of Brain Maturation, Institute of Psychiatry, King s College London, M6 01, P050 De Crespigny Park, London SE5 8AH, United Kingdom
    Neuropsychologia 46:2597-601. 2008

Detail Information

Publications31

  1. pmc Cognitive and connectome properties detectable through individual differences in graphomotor organization
    Melissa Lamar
    Department of Psychiatry, University of Illinois at Chicago, Chicago, IL 60612, United States Graduate Program in Neuroscience, University of Illinois at Chicago, Chicago, IL 60612, United States Electronic address
    Neuropsychologia 85:301-9. 2016
    ..Taken together, these results enhance our knowledge of the brain-behavior relationships underlying unprompted graphomotor organization during dCDT. ..
  2. pmc What Metabolic Syndrome Contributes to Brain Outcomes in African American & Caucasian Cohorts
    Melissa Lamar
    University of Illinois at Chicago, 1601 West Taylor Street MC912, Chicago, IL 60612, USA
    Curr Alzheimer Res 12:640-7. 2015
    ..Care providers may wish to monitor a broader spectrum of risk including components of MetS like blood pressure and cholesterol levels when considering brain-behavior relationships in adults from diverse populations...
  3. pmc In vivo quantification of white matter microstructure for use in aging: a focus on two emerging techniques
    Melissa Lamar
    Department of Psychiatry, University of Illinois at Chicago, Chicago, IL Graduate Program in Neuroscience, University of Illinois at Chicago, Chicago, IL Electronic address
    Am J Geriatr Psychiatry 22:111-21. 2014
    ..More specifically, the methods highlighted in this review may prove more sensitive (and specific) for determining the contribution of myelin versus axonal integrity to the aging of white matter in brain. ..
  4. pmc Prefrontal vulnerabilities and whole brain connectivity in aging and depression
    Melissa Lamar
    Department of Psychiatry, University of Illinois at Chicago, 1601W Taylor St, MC912, Chicago, IL 60601, USA
    Neuropsychologia 51:1463-70. 2013
    ..It appears that the whole brain impact of specific fronto-limbic vulnerabilities in aging may be eclipsed in the presence of disease-specific neuropathology like that seen in late life depression...
  5. pmc Differential associations between types of verbal memory and prefrontal brain structure in healthy aging and late life depression
    Melissa Lamar
    Department of Psychiatry, University of Illinois at Chicago, 1601 West Taylor Street, MC912, Chicago, IL 60612, USA
    Neuropsychologia 50:1823-9. 2012
    ..More specifically, it points toward a network of predominantly anterior brain regions that may underlie the executive contribution to list-learning in older adults with depression...
  6. doi request reprint Down syndrome with and without dementia: an in vivo proton Magnetic Resonance Spectroscopy study with implications for Alzheimer's disease
    Melissa Lamar
    Department of Psychological Medicine, Section of Brain Maturation, Institute of Psychiatry, King s College London, London, England, UK
    Neuroimage 57:63-8. 2011
    ..mI] may modify risk for dementia in this vulnerable population...
  7. ncbi request reprint Serotonin and the neural processing of facial emotions in adults with autism: an fMRI study using acute tryptophan depletion
    Eileen M Daly
    Department of Forensic and Neurodevelopmental Science, Institute of Psychiatry, King s College London, London, England
    Arch Gen Psychiatry 69:1003-13. 2012
    ....
  8. pmc Quantitative tract-specific measures of uncinate and cingulum in major depression using diffusion tensor imaging
    Aifeng Zhang
    Department of Psychiatry, University of Illinois Chicago, Chicago, IL 60612, USA
    Neuropsychopharmacology 37:959-67. 2012
    ..In the MDD group, the severity of depression is associated with reduced NNF in the right UF. These findings have implications for both clinical manifestations of depression as well as its pathophysiology...
  9. pmc Response inhibition and serotonin in autism: a functional MRI study using acute tryptophan depletion
    Eileen Daly
    1 Sackler Institute of Translational Neurodevelopment, Department of Forensic and Neurodevelopmental Science, Institute of Psychiatry, King s College London, UK
    Brain 137:2600-10. 2014
    ..Together these factors may partially explain the severity of autistic behaviours and/or provide a novel (tractable) treatment target. ..
  10. doi request reprint The impact of region-specific leukoaraiosis on working memory deficits in dementia
    Melissa Lamar
    MRC Center for Neurodegeneration, Department of Psychology Section of Brain Maturation, Institute of Psychiatry, King s College London, M6 01, P050 De Crespigny Park, London SE5 8AH, United Kingdom
    Neuropsychologia 46:2597-601. 2008
    ..Results suggest involvement of anterior (fronto-striatal) and more posterior (inferior parietal) white matter tracts in higher order WM deficits in dementia...
  11. pmc Brain connectivity in late-life depression and aging revealed by network analysis
    Rebecca A Charlton
    Department of Psychiatry, University of Illinois at Chicago, Chicago, IL Department of Psychology, Goldsmiths University of London, London, United Kingdom Electronic address
    Am J Geriatr Psychiatry 23:642-50. 2015
    ..Graph theory metrics describe the organizational configuration of both the global network and specified brain regions...
  12. pmc Digital Clock Drawing: differentiating "thinking" versus "doing" in younger and older adults with depression
    Jamie Cohen
    1Department of Psychiatry, University of Illinois at Chicago, Chicago, Illinois
    J Int Neuropsychol Soc 20:920-8. 2014
    ..51; p=.01). The dCDT differentiated aspects of psychomotor slowing in depression regardless of age, while dCDT/cognitive associates for younger adults with depression mimicked patterns of older euthymics...
  13. doi request reprint The impact of subcortical white matter disease on mood in euthymic older adults: a diffusion tensor imaging study
    Melissa Lamar
    Department of Psychology, Institute of Psychiatry, King s College, London, UK
    Am J Geriatr Psychiatry 18:634-42. 2010
    ..We aimed to address these issues with non-demented euthymic older adults...
  14. doi request reprint Acute tryptophan depletion promotes an anterior-to-posterior fMRI activation shift during task switching in older adults
    Melissa Lamar
    Department of Psychology, Institute of Psychiatry, King s College London, Guy s Campus, London United Kingdom Section of Brain Maturation, Department of Forensic and Neurodevelopmental Science, Institute of Psychiatry, King s College London, De Crespigny Park, London, United Kingdom Department of Psychiatry, University of Illinois at Chicago, Chicago, Illinois
    Hum Brain Mapp 35:712-22. 2014
    ..g., in vascular or late life depression)...
  15. pmc The impact of vascular comorbidities on qualitative error analysis of executive impairment in Alzheimer's disease
    Melissa Lamar
    Departments of Psychology and Section of Brain Maturation, Institute of Psychiatry, King s College London, London, England
    J Int Neuropsychol Soc 16:77-83. 2010
    ..Understanding the contribution of VC to patterns of impairment in AD may provide support for directed patient and caregiver education concerning the presentation of a more severe pattern of cognitive impairment in affected individuals...
  16. ncbi request reprint 5-HT, prefrontal function and aging: fMRI of inhibition and acute tryptophan depletion
    Melissa Lamar
    Department of Psychology, Institute of Psychiatry, King s College London, London, UK
    Neurobiol Aging 30:1135-46. 2009
    ..Maintaining successful Simon performance during ATD is achieved by increasing cerebellar and parietal contributions to compensate for decreased fronto-cingulo-striatal involvement...
  17. pmc Graph theory analysis of cortical-subcortical networks in late-life depression
    Olusola Ajilore
    Department of Psychiatry, University of Illinois at Chicago, Chicago, IL Electronic address
    Am J Geriatr Psychiatry 22:195-206. 2014
    ..The purpose of this study was to use interregional correlations of cortical and subcortical volumes to examine cortical-subcortical structural network properties in subjects with LLD compared with healthy comparison subjects...
  18. doi request reprint Memory complaints with and without memory impairment: the impact of leukoaraiosis on cognition
    Melissa Lamar
    Institute of Psychiatry, King s College London, London, United Kingdom
    J Int Neuropsychol Soc 17:1104-12. 2011
    ....
  19. pmc Metabolic Aberrations Impact Biophysical Integrity of Macromolecular Protein Pools in the Default Mode Network
    Shaolin Yang
    Department of Psychiatry, University of Illinois at Chicago, Chicago, IL
    Diabetes 65:3464-3472. 2016
    ....
  20. pmc Investigating the separate and interactive associations of trauma and depression on neurocognition in urban dwelling adults
    Aimee James Karstens
    Department of Psychology, University of Illinois at Chicago, Chicago, IL 60612, United States
    J Psychiatr Res 89:6-13. 2017
    ..We investigated the separate and interactive associations of trauma and depression on neurocognition in a sample of ethnically diverse urban dwellers, and explored the impact of age on these effects...
  21. pmc Preliminary analysis of age of illness onset effects on symptom profiles in major depressive disorder
    Rebecca A Charlton
    Department of Psychiatry, University of Illinois at Chicago, Chicago, IL, USA
    Int J Geriatr Psychiatry 28:1166-74. 2013
    ..Major depressive disorder (MDD) is prevalent across the lifespan, but relatively little is known about how age of illness onset impacts the cognitive and affective presentation of MDD...
  22. doi request reprint The dysexecutive syndrome associated with ischaemic vascular disease and related subcortical neuropathology: a Boston process approach
    Melissa Lamar
    Department of Psychology, Section of Brain Maturation, Institute of Psychiatry, King s College London, London, UK
    Behav Neurol 22:53-62. 2010
    ..e., the dysexecutive phenotype, associated with ischaemic vascular disease and relate it to fundamental impairments of gating subserved by basal ganglia-thalamic pathways within and across various dementia syndromes...
  23. doi request reprint Effects of acute tryptophan depletion on neural processing of facial expressions of emotion in humans
    Eileen Daly
    Section of Brain Maturation, Department of Psychological Medicine and Psychiatry, Institute of Psychiatry, King s College London, London, UK
    Psychopharmacology (Berl) 210:499-510. 2010
    ..Acute tryptophan depletion (ATD) temporarily lowers brain serotonin (5-HT) synthesis, and behavioral studies have shown that this alters the processing of facial expressions of emotion...
  24. pmc Impaired macromolecular protein pools in fronto-striato-thalamic circuits in type 2 diabetes revealed by magnetization transfer imaging
    Shaolin Yang
    Department of Psychiatry, University of Illinois at Chicago, Chicago, IL Department of Radiology, University of Illinois at Chicago, Chicago, IL Department of Bioengineering, University of Illinois at Chicago, Chicago, IL
    Diabetes 64:183-92. 2015
    ....
  25. doi request reprint Associations between vascular risk and mood in euthymic older adults: preliminary findings
    Rebecca A Charlton
    Department of Psychiatry, University of Illinois at Chicago, Chicago, IL Electronic address
    Am J Geriatr Psychiatry 22:936-45. 2014
    ..We explore whether vascular risk is associated with endorsement of depressive symptoms among euthymic older adults and examine associations with cognitive function...
  26. doi request reprint Aging effects on functional auditory and visual processing using fMRI with variable sensory loading
    Michael Cliff
    Department of Psychological Medicine, Institute of Psychiatry, King s College London, London, UK
    Cortex 49:1304-13. 2013
    ..This study provides evidence for age-related functional decline in visual and auditory processing, and regional alterations in functional brain processing, using non-invasive neuroimaging...
  27. pmc Association of brain network efficiency with aging, depression, and cognition
    Olusola Ajilore
    Department of Psychiatry, University of Illinois at Chicago, Chicago, IL Electronic address
    Am J Geriatr Psychiatry 22:102-10. 2014
    ..The purpose of this study was to compare four measures of network efficiency derived from novel techniques for understanding white matter connectivity on their associations with aging, depression, and cognition...
  28. pmc Alterations in working memory as a function of leukoaraiosis in dementia
    Melissa Lamar
    Institute of Psychiatry, King s College London, Department of Psychology, De Crespigny Park, London, UK
    Neuropsychologia 45:245-54. 2007
    ..LA may disconnect the frontal lobes from subcortical and cortical structures that form the neuronal networks critical for these WM functions...
  29. pmc Domain-specific impairment in cognitive control among remitted youth with a history of major depression
    Amy T Peters
    Departments of Psychology and Psychiatry, University of Illinois at Chicago, Chicago, Illinois
    Early Interv Psychiatry . 2015
    ....
  30. pmc Pulse Pressure Is Associated With Early Brain Atrophy and Cognitive Decline: Modifying Effects of APOE-ε4
    Daniel A Nation
    Department of Psychology, University of Southern California, Los Angeles Veterans Affairs San Diego Healthcare System Department of Psychiatry, University of California, San Diego, La Jolla, CA The Framingham Heart Study, FraminghamDepartments of Biostatistics Department of Neurology, Boston University School of Medicine, Boston, MA Department of Psychiatry, University of Illinois at Chicago, Chicago, IL Drexel Neuroscience Institute, College of Medicine, Drexel University, Philadelphia, PA
    Alzheimer Dis Assoc Disord 30:210-5. 2016
    ..Findings indicate arterial stiffening, indexed by pulse pressure, may play a role in early cognitive decline and brain atrophy in mid to late life, particularly among APOE-ε4 carriers. ..
  31. doi request reprint Comparison of deck- and trial-based approaches to advantageous decision making on the Iowa Gambling Task
    Ravindran Visagan
    School of Biomedical and Health Sciences, Guy s Campus, and Department of Psychology, Institute of Psychiatry, King s College London, London, United Kingdom
    Psychol Assess 24:455-63. 2012
    ....