G J LaHoste
Affiliation: University of New Orleans
- Attenuation of Rhes activity significantly delays the appearance of behavioral symptoms in a mouse model of Huntington's diseaseBrandon A Baiamonte
Applied Biopsychology Program, Department of Psychology, University of New Orleans, New Orleans, Louisiana, United States of America
PLoS ONE 8:e53606. 2013..HD(+)/Rhes(-/-) mice showed significantly delayed expression of HD-like symptoms in this in vivo model. Drugs that block or inhibit the actions of Rhes may be useful as the first treatments for HD...
- Carbamazepine reduces dopamine-mediated behavior in chronic neuroleptic-treated and untreated rats: implications for treatment of tardive dyskinesia and hyperdopaminergic statesG J LaHoste
Department of Psychology, University of New Orleans, Lake Front Louisiana 70148, USA
Exp Clin Psychopharmacol 8:125-32. 2000..Striatal D1 DA receptor density was elevated by chronic CBZ but unaffected by HAL. These findings suggest that by reducing DA supersensitivity, CBZ may be useful in treating TD and other hyperdopaminergic states...
- Dopamine D1 receptors synergize with D2, but not D3 or D4, receptors in the striatum without the involvement of action potentialsG J LaHoste
Department of Psychology, University of New Orleans, New Orleans, Louisiana 70148, USA
J Neurosci 20:6666-71. 2000....
- Rhes, the Ras homolog enriched in striatum, is reduced under conditions of dopamine supersensitivityL M Harrison
Department of Psychology, University of New Orleans, 2000 Lakeshore Drive, LA 70148, USA
Neuroscience 137:483-92. 2006..These findings suggest that rhes mRNA expression is maintained by dopamine and may play a role in determining normal dopamine receptor sensitivity...
- Dopamine D4 receptor gene polymorphism is associated with attention deficit hyperactivity disorderG J LaHoste
Department of Physical Medicine and Rehabilitation, University of California, Irvine 92717 4550, USA
Mol Psychiatry 1:121-4. 1996....