Genomes and Genes
Affiliation: University of California
- Impact of scanner hardware and imaging protocol on image quality and compartment volume precision in the ADNI cohortFrithjof Kruggel
Department of Biomedical Engineering, University of California, Irvine, CA 92697 2755, USA
Neuroimage 49:2123-33. 2010..Two likely factors explaining this finding are scanner-dependent geometrical inaccuracies and differences in the white/grey matter tissue contrast...
- Robust parametrization of brain surface meshesFrithjof Kruggel
Department of Biomedical Engineering, University of California, 204 Rockwell Engineering Center, Irvine, CA 92697 2755, USA
Med Image Anal 12:291-9. 2008..A multi-resolution scheme provides the robustness required to map the highly detailed and convoluted brain surface. More than 1000 datasets were successfully processed by this mature and robust approach...
- Texture-based segmentation of diffuse lesions of the brain's white matterFrithjof Kruggel
204 Rockwell Engineering Center, University of California, Irvine, CA 92697 2755, USA
Neuroimage 39:987-96. 2008..Texture-based segmentation can be considered as a general method for lesion segmentation, and an outline for adapting this method to similar problems is presented...
- Quantitative comparison of high-resolution MRI and myelin-stained histology of the human cerebral cortexSergey Osechinskiy
Department of Biomed ical Engineering, University of California, Irvine, CA 92697, USA
Conf Proc IEEE Eng Med Biol Soc 2009:85-9. 2009....
- Hippocampal atrophy as a quantitative trait in a genome-wide association study identifying novel susceptibility genes for Alzheimer's diseaseSteven G Potkin
Department of Psychiatry and Human Behavior, University of California Irvine, Irvine, CA, USA
PLoS ONE 4:e6501. 2009..With the exception of APOE epsilon4 allele, the common genetic risk factors for sporadic Alzheimer's Disease (AD) are unknown...
- Effects of advanced aging on the neural correlates of successful recognition memoryTracy H Wang
Center for the Neurobiology of Learning and Memory, and Department of Neurobiology and Behavior, University of California, Irvine, Irvine, CA 92697 3800, United States
Neuropsychologia 47:1352-61. 2009..The findings for the medial parietal cortex underscore the sensitivity of this cortical region to increasing age...
- Automatic segmentation of human brain sulciFaguo Yang
Signal and Image Processing Laboratory, Department of Biomedical Engineering, University of California, Irvine, CA 92697 2755, USA
Med Image Anal 12:442-51. 2008..Then, vertices are collected into sulcal regions by a watershed-like growing method. Experimental results demonstrate that the method is accurate and robust...
- PDE-based reconstruction of the cerebral cortex from MR imagesSergey Osechinskiy
Department of Biomedical Engineering, University of California, Irvine, CA 92697, USA
Conf Proc IEEE Eng Med Biol Soc 2010:4278-83. 2010..In addition, the deformable model may use the distance field as a constraint on thickness of the reconstructed cortical layer...
- Gender and age effects in structural brain asymmetry as measured by MRI texture analysisVassili A Kovalev
Max Planck Institute of Cognitive Neuroscience, Stephanstrasse 1a, D 04103 Leipzig, Germany
Neuroimage 19:895-905. 2003..Thus, it should be considered as another tool for digital morphometry in neuroscience...
- Texture anisotropy of the brain's white matter as revealed by anatomical MRIVassili Kovalev
United Institute of Informatics Problems, Belarus National Academy of Sciences, 220012 Minsk, Belarus
IEEE Trans Med Imaging 26:678-85. 2007..02). Texture analysis of anatomical MRI-T1 brain datasets provides quantitative information about macroscopic WM characteristics and helps discriminating between normal and pathological aging...
- Quasi-real-time neurosurgery support by MRI processing via grid computingHeiko Lippmann
Max Planck Institute for Human Cognitive and Brain Sciences, Stephanstrasse 1, D 04103 Leipzig, Germany
Neurosurg Clin N Am 16:65-75. 2005....
- Structural correlates of mild cognitive impairmentHenrike Wolf
Department of Psychiatry, University of Leipzig, Leipzig, Germany
Neurobiol Aging 25:913-24. 2004..Widespread brain atrophy may be the step to determine the transition from MCI to dementia. Brain volume reserve effects appear to be involved in both of these steps...
- An object-based approach for detecting small brain lesions: application to Virchow-Robin spacesXavier Descombes
Ariana, common project CNRS INRIA UNSA, INRIA, BP93, 2004 route des Lucioles, 06902 Sophia Antipolis Cedex, France
IEEE Trans Med Imaging 23:246-55. 2004..A Reversible Jump Markov Chain Monte Carlo algorithm (RJMCMC) optimizes the proposed model, obtained by multiplying the prior and the data model. Example results are shown on T1-weighted MRI datasets of elderly subjects...
- Age dependency of the hemodynamic response as measured by functional near-infrared spectroscopyMatthias L Schroeter
Max Planck Institute of Cognitive Neuroscience, Stephanstrasse 1a, 04103 Leipzig, Germany
Neuroimage 19:555-64. 2003..In summary, our findings suggest that aging decreases the hemodynamic response in the frontal association cortex during functional activation, omitting the primary motor cortex...
- Do quiescent arachnoid cysts alter CNS functional organization?: A fMRI and morphometric studyMargret Hund-Georgiadis
Max Planck Institute of Cognitive Neuroscience, Leipzig, Germany
Neurology 59:1935-9. 2002..To investigate whether congenital and clinically quiescent arachnoid cysts (AC) in the left temporal fossa alter the functional organization of adjacent cortices...
- Computional cost of nonrigid registration algorithms based on fluid dynamicsGert Wollny
Max Plank Institute of Cognitive Neuroscience, 04103 Leipzig, Germany
IEEE Trans Med Imaging 21:946-52. 2002..Numerical experiments show that relaxation is currently the best approach, especially when reducing the cost/iteration by focusing the updates on deformation spots...
- ICA of fMRI group study dataMarkus Svensén
Max Planck Institute of Cognitive Neuroscience, Leipzig, Germany
Neuroimage 16:551-63. 2002....
- Theta-power differences in patients with mild cognitive impairment under rest condition and during haptic tasksMartin Grunwald
University of Leipzig, Department of Psychiatry, EEG Research Laboratory and Memory Clinic, Leipzig, Germany
Alzheimer Dis Assoc Disord 16:40-8. 2002..The results show that haptic tasks are sensitive to early perceptive-cognitive and functional deficits in patients with MCI...