Esther Krook-Magnuson

Summary

Affiliation: University of California
Country: USA

Publications

  1. pmc How might novel technologies such as optogenetics lead to better treatments in epilepsy?
    Esther Krook-Magnuson
    Department of Anatomy and Neurobiology, University of California, 192 Irvine Hall, Irvine, CA, 92697, USA
    Adv Exp Med Biol 813:319-36. 2014
  2. pmc On-demand optogenetic control of spontaneous seizures in temporal lobe epilepsy
    Esther Krook-Magnuson
    Department of Anatomy and Neurobiology, University of California, Irvine, California 92697 1280, USA
    Nat Commun 4:1376. 2013
  3. pmc New dimensions of interneuronal specialization unmasked by principal cell heterogeneity
    Esther Krook-Magnuson
    Department of Anatomy and Neurobiology, University of California, Irvine, CA 92697 1280, USA
    Trends Neurosci 35:175-84. 2012
  4. pmc Ivy and neurogliaform interneurons are a major target of μ-opioid receptor modulation
    Esther Krook-Magnuson
    Department of Anatomy and Neurobiology, University of California, Irvine, California 92697 1280, USA
    J Neurosci 31:14861-70. 2011
  5. pmc In vivo evaluation of the dentate gate theory in epilepsy
    Esther Krook-Magnuson
    Department of Anatomy and Neurobiology, University of California, Irvine, USA
    J Physiol 593:2379-88. 2015
  6. pmc Closed-loop optogenetic intervention in mice
    Caren Armstrong
    Department of Anatomy and Neurobiology, University of California, Irvine, School of Medicine, Irvine, California, USA
    Nat Protoc 8:1475-93. 2013
  7. pmc Future of seizure prediction and intervention: closing the loop
    Vivek Nagaraj
    Graduate Program in Neuroscience, University of Minnesota, Minneapolis, MN Weldon School of Biomedical Engineering, Purdue University, West Lafayette, IN Department of Anatomy and Neurobiology, University of California, Irvine, CA INSERM U1099 LTSI, University of Rennes 1, Rennes, France and Department of Biomedical Engineering, University of Minnesota, Minneapolis, MN
    J Clin Neurophysiol 32:194-206. 2015
  8. pmc Beyond the hammer and the scalpel: selective circuit control for the epilepsies
    Esther Krook-Magnuson
    Department of Anatomy and Neurobiology, University of California, Irvine, Irvine, California, USA
    Nat Neurosci 18:331-8. 2015
  9. pmc Neurogliaform and Ivy Cells: A Major Family of nNOS Expressing GABAergic Neurons
    Caren Armstrong
    Department of Anatomy and Neurobiology, University of California Irvine Irvine, CA, USA
    Front Neural Circuits 6:23. 2012

Detail Information

Publications9

  1. pmc How might novel technologies such as optogenetics lead to better treatments in epilepsy?
    Esther Krook-Magnuson
    Department of Anatomy and Neurobiology, University of California, 192 Irvine Hall, Irvine, CA, 92697, USA
    Adv Exp Med Biol 813:319-36. 2014
    ..We then turn to the use of optogenetics, including on-demand optogenetics in the study of epilepsies, which highlights the powerful potential of optogenetics for epilepsy research. ..
  2. pmc On-demand optogenetic control of spontaneous seizures in temporal lobe epilepsy
    Esther Krook-Magnuson
    Department of Anatomy and Neurobiology, University of California, Irvine, California 92697 1280, USA
    Nat Commun 4:1376. 2013
    ..A clinical approach built on these principles may overcome many of the side-effects of currently available treatment options...
  3. pmc New dimensions of interneuronal specialization unmasked by principal cell heterogeneity
    Esther Krook-Magnuson
    Department of Anatomy and Neurobiology, University of California, Irvine, CA 92697 1280, USA
    Trends Neurosci 35:175-84. 2012
    ..This organization represents a novel form of interneuron specialization, providing interneurons with the potential to selectively regulate specific information-processing streams...
  4. pmc Ivy and neurogliaform interneurons are a major target of μ-opioid receptor modulation
    Esther Krook-Magnuson
    Department of Anatomy and Neurobiology, University of California, Irvine, California 92697 1280, USA
    J Neurosci 31:14861-70. 2011
    ..Given the prominence of this cell type in and beyond CA1, as well as its unique role in microcircuitry, opioid modulation of neurogliaform cells has wide implications...
  5. pmc In vivo evaluation of the dentate gate theory in epilepsy
    Esther Krook-Magnuson
    Department of Anatomy and Neurobiology, University of California, Irvine, USA
    J Physiol 593:2379-88. 2015
    ..These data indicate that the dentate gyrus is a critical node in the temporal lobe seizure network, and provide the first in vivo support for the dentate 'gate' hypothesis...
  6. pmc Closed-loop optogenetic intervention in mice
    Caren Armstrong
    Department of Anatomy and Neurobiology, University of California, Irvine, School of Medicine, Irvine, California, USA
    Nat Protoc 8:1475-93. 2013
    ..We describe the basic construction of a complete system, and we include our downloadable custom closed-loop detection software, which can be used for this purpose. ..
  7. pmc Future of seizure prediction and intervention: closing the loop
    Vivek Nagaraj
    Graduate Program in Neuroscience, University of Minnesota, Minneapolis, MN Weldon School of Biomedical Engineering, Purdue University, West Lafayette, IN Department of Anatomy and Neurobiology, University of California, Irvine, CA INSERM U1099 LTSI, University of Rennes 1, Rennes, France and Department of Biomedical Engineering, University of Minnesota, Minneapolis, MN
    J Clin Neurophysiol 32:194-206. 2015
    ..Seizure prediction and therapies maximize efficacy, whereas minimizing side effects through improved specificity may represent the future of epilepsy treatments. ..
  8. pmc Beyond the hammer and the scalpel: selective circuit control for the epilepsies
    Esther Krook-Magnuson
    Department of Anatomy and Neurobiology, University of California, Irvine, Irvine, California, USA
    Nat Neurosci 18:331-8. 2015
    ..In this Perspective, we discuss promising uses of these technologies for the study of seizures and epilepsy, as well as potential use of these strategies for clinical therapies. ..
  9. pmc Neurogliaform and Ivy Cells: A Major Family of nNOS Expressing GABAergic Neurons
    Caren Armstrong
    Department of Anatomy and Neurobiology, University of California Irvine Irvine, CA, USA
    Front Neural Circuits 6:23. 2012
    ....